troglitazone has been researched along with Arrhythmia in 4 studies
Troglitazone: A chroman and thiazolidinedione derivative that acts as a PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) agonist. It was formerly used in the treatment of TYPE 2 DIABETES MELLITUS, but has been withdrawn due to hepatotoxicity.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We previously demonstrated that chronic pretreatment with a thiazolidinedione peroxisome proliferator-activated receptor (PPAR)-gamma activator, troglitazone, improves recovery of left ventricular (LV) function and substrate metabolism after ischemia and reperfusion, without causing arrhythmias." | 3.72 | Deleterious effects of acute treatment with a peroxisome proliferator-activated receptor-gamma activator in myocardial ischemia and reperfusion in pigs. ( Gen, M; Greyson, C; Kinugawa, K; Lee, J; Long, CS; Lu, L; Schwartz, GG; Xu, Y, 2003) |
| "There is evidence that one of the key type 2 diabetes (T2D) loci identified by GWAS exerts its influence early on in life through its impact on pediatric BMI." | 1.38 | Expression analyses of the genes harbored by the type 2 diabetes and pediatric BMI associated locus on 10q23. ( Aziz, AR; Deliard, S; Grant, SF; Zhao, J, 2012) |
| "Troglitazone treatment improved ischemic tolerance by improving glucose metabolism in the myocardium of those rats." | 1.34 | Exacerbation of acidosis during ischemia and reperfusion arrhythmia in hearts from type 2 Diabetic Otsuka Long-Evans Tokushima Fatty rats. ( Anzawa, R; Horikoshi, K; Mochizuki, S; Seki, S; Taniguchi, M, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhao, J | 1 |
| Deliard, S | 1 |
| Aziz, AR | 1 |
| Grant, SF | 1 |
| Xu, Y | 1 |
| Lu, L | 1 |
| Greyson, C | 1 |
| Lee, J | 1 |
| Gen, M | 1 |
| Kinugawa, K | 1 |
| Long, CS | 1 |
| Schwartz, GG | 1 |
| Anzawa, R | 1 |
| Seki, S | 1 |
| Horikoshi, K | 1 |
| Taniguchi, M | 1 |
| Mochizuki, S | 1 |
| Greene, HL | 1 |
4 other studies available for troglitazone and Arrhythmia
| Article | Year |
|---|---|
Expression analyses of the genes harbored by the type 2 diabetes and pediatric BMI associated locus on 10q23.
Topics: Adipocytes; Adipogenesis; Arrhythmias, Cardiac; Body Mass Index; Cell Line; Chromans; Chromosomes, H | 2012 |
Deleterious effects of acute treatment with a peroxisome proliferator-activated receptor-gamma activator in myocardial ischemia and reperfusion in pigs.
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Chromans; Disease Models, Animal; Gene Expression Reg | 2003 |
Exacerbation of acidosis during ischemia and reperfusion arrhythmia in hearts from type 2 Diabetic Otsuka Long-Evans Tokushima Fatty rats.
Topics: Animals; Arrhythmias, Cardiac; Blood Glucose; Chromans; Diabetes Mellitus, Type 2; Diabetic Ketoacid | 2007 |
Drug recalls underscore safety concerns.
Topics: Arrhythmias, Cardiac; Chromans; Cisapride; Drug and Narcotic Control; Gastrointestinal Agents; Human | 2000 |