troglitazone has been researched along with Anaplastic Astrocytoma in 3 studies
Troglitazone: A chroman and thiazolidinedione derivative that acts as a PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) agonist. It was formerly used in the treatment of TYPE 2 DIABETES MELLITUS, but has been withdrawn due to hepatotoxicity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "However, its expression in brain tumors has not been studied." | 1.31 | Expression of PPARgamma and its ligand-dependent growth inhibition in human brain tumor cell lines. ( Fujieda, M; Kato, M; Nagaya, T; Saito, K; Seo, H; Yoshida, J, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kambe, A | 1 |
| Iguchi, G | 1 |
| Moon, Y | 1 |
| Kamitani, H | 1 |
| Watanabe, T | 1 |
| Eling, TE | 1 |
| Wu, L | 1 |
| Eftekharpour, E | 1 |
| Davies, GF | 1 |
| Roesler, WJ | 1 |
| Juurlink, BH | 1 |
| Kato, M | 1 |
| Nagaya, T | 1 |
| Fujieda, M | 1 |
| Saito, K | 1 |
| Yoshida, J | 1 |
| Seo, H | 1 |
3 other studies available for troglitazone and Anaplastic Astrocytoma
| Article | Year |
|---|---|
Regulation of EP4 expression via the Sp-1 transcription factor: inhibition of expression by anti-cancer agents.
Topics: Antineoplastic Agents; Astrocytoma; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; | 2008 |
Troglitazone selectively inhibits glyoxalase I gene expression.
Topics: Animals; Antioxidants; Astrocytoma; Cell Culture Techniques; Cells, Cultured; Chromans; Gene Express | 2001 |
Expression of PPARgamma and its ligand-dependent growth inhibition in human brain tumor cell lines.
Topics: Antineoplastic Agents; Apoptosis; Astrocytoma; Blotting, Northern; Brain Neoplasms; Cell Division; C | 2002 |