troglitazone and Alcohol Drinking studies

troglitazone and Alcohol Drinking

troglitazone has been researched along with Alcohol Drinking in 2 studies

Troglitazone: A chroman and thiazolidinedione derivative that acts as a PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) agonist. It was formerly used in the treatment of TYPE 2 DIABETES MELLITUS, but has been withdrawn due to hepatotoxicity.

Alcohol Drinking: Behaviors associated with the ingesting of ALCOHOLIC BEVERAGES, including social drinking.

Research Excerpts

Excerpt	Relevance	Reference
"Treatment with metformin was less effective than lifestyle modifications, resulting in an average reduction of risk for development of type 2 diabetes by 31% compared with placebo."	2.42	[Progress in the prevention of type 2 diabetes]. ( Schernthaner, G, 2003)
" In addition, we found that rosiglitazone, although less toxic in the study population, was cytotoxic to hepatocytes in some donors (EC(50)<100 microM)."	1.31	Differential in vitro hepatotoxicity of troglitazone and rosiglitazone among cryopreserved human hepatocytes from 37 donors. ( Fackett, A; Hayden, MJ; Hewitt, NJ; Li, AP; Lloyd, S; Sakai, Y; Silber, PM, 2002)

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

0 (0.00)

18.7374

1990's

0 (0.00)

18.2507

2000's

2 (100.00)

29.6817

2010's

0 (0.00)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Lloyd, S	1
Hayden, MJ	1
Sakai, Y	1
Fackett, A	1
Silber, PM	1
Hewitt, NJ	1
Li, AP	1
Schernthaner, G	1

Studies

Lloyd, S

Hayden, MJ

Sakai, Y

Fackett, A

Silber, PM

Hewitt, NJ

Li, AP

Schernthaner, G

Reviews

1 review available for troglitazone and Alcohol Drinking

Article	Year
[Progress in the prevention of type 2 diabetes]. Wiener klinische Wochenschrift, 2003, Nov-28, Volume: 115, Issue:21-22 Topics: Acarbose; Adult; Alcohol Drinking; Angiotensin-Converting Enzyme Inhibitors; Blood Glucose; Chromans	2003

Article

Year

[Progress in the prevention of type 2 diabetes].

Wiener klinische Wochenschrift, 2003, Nov-28, Volume: 115, Issue:21-22

Topics: Acarbose; Adult; Alcohol Drinking; Angiotensin-Converting Enzyme Inhibitors; Blood Glucose; Chromans

2003

Other Studies

1 other study available for troglitazone and Alcohol Drinking

Article	Year
Differential in vitro hepatotoxicity of troglitazone and rosiglitazone among cryopreserved human hepatocytes from 37 donors. Chemico-biological interactions, 2002, Nov-10, Volume: 142, Issue:1-2 Topics: Adenosine Triphosphate; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Alcohol Drinking; C	2002

Article

Year

Differential in vitro hepatotoxicity of troglitazone and rosiglitazone among cryopreserved human hepatocytes from 37 donors.

Chemico-biological interactions, 2002, Nov-10, Volume: 142, Issue:1-2

Topics: Adenosine Triphosphate; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Alcohol Drinking; C

2002