troglitazone has been researched along with Adenomatous Polyposis Coli in 3 studies
Troglitazone: A chroman and thiazolidinedione derivative that acts as a PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) agonist. It was formerly used in the treatment of TYPE 2 DIABETES MELLITUS, but has been withdrawn due to hepatotoxicity.
Adenomatous Polyposis Coli: A polyposis syndrome due to an autosomal dominant mutation of the APC genes (GENES, APC) on CHROMOSOME 5. The syndrome is characterized by the development of hundreds of ADENOMATOUS POLYPS in the COLON and RECTUM of affected individuals by early adulthood.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Seed, B | 1 |
| Saez, E | 1 |
| Tontonoz, P | 1 |
| Nelson, MC | 1 |
| Alvarez, JG | 1 |
| Ming, UT | 1 |
| Baird, SM | 1 |
| Thomazy, VA | 1 |
| Evans, RM | 1 |
3 other studies available for troglitazone and Adenomatous Polyposis Coli
| Article | Year |
|---|---|
PPAR--the good news and the bad.
Topics: Adenomatous Polyposis Coli; Animals; Chromans; Humans; Hypoglycemic Agents; Mice; Receptors, Cytopla | 1998 |
PPARgamma and colorectal carcinoma: conflicts in a nuclear family.
Topics: Adenomatous Polyposis Coli; Animals; Chromans; Colorectal Neoplasms; Humans; Mice; Receptors, Cytopl | 1998 |
Activators of the nuclear receptor PPARgamma enhance colon polyp formation.
Topics: Adenocarcinoma; Adenomatous Polyposis Coli; Animals; Chromans; Diet; Humans; Ligands; Mice; Mice, In | 1998 |