troglitazone has been researched along with Adenoma, beta-Cell in 2 studies
Troglitazone: A chroman and thiazolidinedione derivative that acts as a PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) agonist. It was formerly used in the treatment of TYPE 2 DIABETES MELLITUS, but has been withdrawn due to hepatotoxicity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Insulinoma cell line beta-cell (INS-1 cells) were treated with PPARalpha ligand (clofibrate) and PPARgamma ligands (troglitazone and thiazolidinedione)." | 3.72 | [The effect of peroxisome proliferator-activated receptor alpha and gamma ligands on free fatty acid-induced INS-1 cell impairment]. ( Chen, ZJ; Yang, LY; Yang, YN, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, LY | 1 |
| Yang, YN | 1 |
| Chen, ZJ | 1 |
| Kawai, T | 1 |
| Hirose, H | 1 |
| Seto, Y | 1 |
| Fujita, H | 2 |
| Ukeda, K | 1 |
| Saruta, T | 1 |
2 other studies available for troglitazone and Adenoma, beta-Cell
| Article | Year |
|---|---|
[The effect of peroxisome proliferator-activated receptor alpha and gamma ligands on free fatty acid-induced INS-1 cell impairment].
Topics: Animals; Anticholesteremic Agents; Apoptosis; Cell Line, Tumor; Chromans; Clofibrate; Fatty Acids, N | 2003 |
Troglitazone ameliorates lipotoxicity in the beta cell line INS-1 expressing PPAR gamma.
Topics: Animals; Base Sequence; Cell Division; Cell Survival; Chromans; DNA Primers; Fatty Acids, Nonesterif | 2002 |