troglitazone has been researched along with Acute Kidney Injury in 2 studies
Troglitazone: A chroman and thiazolidinedione derivative that acts as a PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) agonist. It was formerly used in the treatment of TYPE 2 DIABETES MELLITUS, but has been withdrawn due to hepatotoxicity.
Acute Kidney Injury: Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Renal ischemia-reperfusion injury affects the long-term outcome of renal graft survival." | 1.34 | Protective effects of peroxisome proliferator-activated receptor gamma ligand on apoptosis and hepatocyte growth factor induction in renal ischemia-reperfusion injury. ( Arakawa, T; Doi, S; Kawai, T; Kohno, N; Masaki, T; Naito, T; Nakashima, A; Takahashi, S; Yorioka, N, 2007) |
| "Troglitazone is a thiazolidinedione with insulin-sensitizing activities when administered to humans or animals with type 2 diabetes mellitus." | 1.31 | Case of the month. Hepatic and renal failure in a patient taking troglitazone and metformin. ( Chaudhry, MU; Simmons, DL, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Doi, S | 1 |
| Masaki, T | 1 |
| Arakawa, T | 1 |
| Takahashi, S | 1 |
| Kawai, T | 1 |
| Nakashima, A | 1 |
| Naito, T | 1 |
| Kohno, N | 1 |
| Yorioka, N | 1 |
| Chaudhry, MU | 1 |
| Simmons, DL | 1 |
2 other studies available for troglitazone and Acute Kidney Injury
| Article | Year |
|---|---|
Protective effects of peroxisome proliferator-activated receptor gamma ligand on apoptosis and hepatocyte growth factor induction in renal ischemia-reperfusion injury.
Topics: Acute Kidney Injury; Animals; Apoptosis; Blotting, Western; Caspase 3; Chromans; Creatinine; Disease | 2007 |
Case of the month. Hepatic and renal failure in a patient taking troglitazone and metformin.
Topics: Acute Kidney Injury; Chromans; Drug Therapy, Combination; Humans; Hypoglycemic Agents; Liver Failure | 2001 |