Page last updated: 2024-11-05

troglitazone and Acute Kidney Injury

troglitazone has been researched along with Acute Kidney Injury in 2 studies

Troglitazone: A chroman and thiazolidinedione derivative that acts as a PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) agonist. It was formerly used in the treatment of TYPE 2 DIABETES MELLITUS, but has been withdrawn due to hepatotoxicity.

Acute Kidney Injury: Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.

Research Excerpts

ExcerptRelevanceReference
"Renal ischemia-reperfusion injury affects the long-term outcome of renal graft survival."1.34Protective effects of peroxisome proliferator-activated receptor gamma ligand on apoptosis and hepatocyte growth factor induction in renal ischemia-reperfusion injury. ( Arakawa, T; Doi, S; Kawai, T; Kohno, N; Masaki, T; Naito, T; Nakashima, A; Takahashi, S; Yorioka, N, 2007)
"Troglitazone is a thiazolidinedione with insulin-sensitizing activities when administered to humans or animals with type 2 diabetes mellitus."1.31Case of the month. Hepatic and renal failure in a patient taking troglitazone and metformin. ( Chaudhry, MU; Simmons, DL, 2001)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Doi, S1
Masaki, T1
Arakawa, T1
Takahashi, S1
Kawai, T1
Nakashima, A1
Naito, T1
Kohno, N1
Yorioka, N1
Chaudhry, MU1
Simmons, DL1

Other Studies

2 other studies available for troglitazone and Acute Kidney Injury

ArticleYear
Protective effects of peroxisome proliferator-activated receptor gamma ligand on apoptosis and hepatocyte growth factor induction in renal ischemia-reperfusion injury.
    Transplantation, 2007, Jul-27, Volume: 84, Issue:2

    Topics: Acute Kidney Injury; Animals; Apoptosis; Blotting, Western; Caspase 3; Chromans; Creatinine; Disease

2007
Case of the month. Hepatic and renal failure in a patient taking troglitazone and metformin.
    The Journal of the Arkansas Medical Society, 2001, Volume: 98, Issue:1

    Topics: Acute Kidney Injury; Chromans; Drug Therapy, Combination; Humans; Hypoglycemic Agents; Liver Failure

2001