Page last updated: 2024-09-02

triptolide and Proteinuria

triptolide has been researched along with Proteinuria in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (18.18)29.6817
2010's7 (63.64)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Ji, B; Liu, J; Ma, Y; Shen, Q; Xu, H; Yin, Y; Yu, J1
Ji, B; Liu, J; Shen, Q; Xu, H; Yin, Y; Yu, J1
Chen, D; Fu, L; Gu, J; He, L; Jing, Y; Li, L; Mei, C; Mei, S; Qi, N; Wu, M; Yang, M; Zhang, D1
Chen, Z; Hou, Q; Liu, Z; Wang, L; Zhang, L; Zhu, X1
Chen, H; Li, Z; Song, H; Sun, L; Tang, X; Wang, D; Yan, Q; Zhao, X1
Du, L; Fu, H; Jin, X; Liu, A; Mao, J; Shen, H; Shu, Q; Wang, J; Wu, L1
Chen, D; Dai, B; Li, L; Liu, H; Liu, S; Ma, Y; Mao, Z; Mei, C; Wang, X; Yu, S1
Chen, ZH; Li, LS; Liu, ZH; Qin, WS; Zeng, CH; Zheng, CX1
Chen, ZH; Hong, YM; Li, LS; Liu, ZH; Lu, YZ; Qin, WS; Zeng, CH; Zheng, CX1
Cao, L; Chen, Y; Du, L; Fu, H; Liu, A; Mao, J; Wang, D; Xia, Y; Yao, S1
Dong, J; Liu, MX; Xu, HB; Yang, XL; Yang, YJ1

Trials

1 trial(s) available for triptolide and Proteinuria

ArticleYear
Efficacy of triptolide for children with moderately severe Henoch-Schönlein purpura nephritis presenting with nephrotic range proteinuria: a prospective and controlled study in China.
    BioMed research international, 2013, Volume: 2013

    Topics: Biopsy; Child; Child, Preschool; China; Diterpenes; Drugs, Chinese Herbal; Epoxy Compounds; Female; Humans; IgA Vasculitis; Kaplan-Meier Estimate; Male; Nephritis; Phenanthrenes; Proteinuria

2013

Other Studies

10 other study(ies) available for triptolide and Proteinuria

ArticleYear
Minnelide combined with Angptl3 knockout completely protects mice with adriamycin nephropathy via suppression of TGF-β1-Smad2 and p53 pathways.
    International immunopharmacology, 2023, Volume: 115

    Topics: Angiopoietin-Like Protein 3; Animals; Doxorubicin; Female; Kidney Diseases; Mice; Mice, Knockout; Podocytes; Proteinuria; Transforming Growth Factor beta1; Tumor Suppressor Protein p53

2023
Minnelide combined with anti-ANGPTL3-FLD monoclonal antibody completely protects mice with adriamycin nephropathy by promoting autophagy and inhibiting apoptosis.
    Cell death & disease, 2023, 09-09, Volume: 14, Issue:9

    Topics: Animals; Antibodies, Monoclonal; Apoptosis; Autophagy; Doxorubicin; Female; Kidney Diseases; Mice; Mice, Inbred C57BL; Proteinuria

2023
Triptolide delays disease progression in an adult rat model of polycystic kidney disease through the JAK2-STAT3 pathway.
    American journal of physiology. Renal physiology, 2018, 09-01, Volume: 315, Issue:3

    Topics: Animals; Apoptosis; Blood Urea Nitrogen; Cell Line; Cell Proliferation; Creatinine; Disease Models, Animal; Disease Progression; Diterpenes; Epoxy Compounds; Humans; Interleukin-6; Janus Kinase 2; Kidney; Male; Phenanthrenes; Phosphorylation; Polycystic Kidney Diseases; Proteinuria; Rats, Transgenic; Receptors, Interleukin-6; Signal Transduction; STAT3 Transcription Factor; Suppressor of Cytokine Signaling 3 Protein

2018
Triptolide attenuates proteinuria and podocyte apoptosis via inhibition of NF-κB/GADD45B.
    Scientific reports, 2018, Jul-18, Volume: 8, Issue:1

    Topics: Animals; Animals, Genetically Modified; Anti-Infective Agents; Antigens, Differentiation; Apoptosis; Cells, Cultured; Diterpenes; Epoxy Compounds; Humans; Immunosuppressive Agents; Metronidazole; NF-kappa B; Phenanthrenes; Podocytes; Proteinuria; Zebrafish; Zebrafish Proteins

2018
Triptolide ameliorates lupus via the induction of miR-125a-5p mediating Treg upregulation.
    International immunopharmacology, 2019, Volume: 71

    Topics: Animals; Antibodies, Antinuclear; Antirheumatic Agents; Cell Proliferation; Disease Models, Animal; Diterpenes; Epoxy Compounds; Female; Humans; Kidney; Lupus Erythematosus, Systemic; Mice; Mice, Inbred C57BL; Mice, Inbred MRL lpr; MicroRNAs; Phenanthrenes; Proteinuria; T-Lymphocytes, Regulatory; Up-Regulation

2019
Triptolide-containing formulation in patients with autosomal dominant polycystic kidney disease and proteinuria: an uncontrolled trial.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2014, Volume: 63, Issue:6

    Topics: Adult; Diterpenes; Epoxy Compounds; Female; Humans; Male; Medicine, East Asian Traditional; Middle Aged; Phenanthrenes; Phytotherapy; Polycystic Kidney, Autosomal Dominant; Proteinuria; Treatment Outcome; Tripterygium

2014
Triptolide protects podocytes from puromycin aminonucleoside induced injury in vivo and in vitro.
    Kidney international, 2008, Volume: 74, Issue:5

    Topics: Animals; Cells, Cultured; Cholesterol; Cytoskeleton; Desmin; Diterpenes; Epoxy Compounds; Glomerular Filtration Rate; Intracellular Signaling Peptides and Proteins; MAP Kinase Signaling System; Membrane Proteins; Mice; Nephrosis; Phenanthrenes; Podocytes; Proteinuria; Puromycin Aminonucleoside; Rats; Reactive Oxygen Species; Serum Albumin; Triglycerides

2008
Triptolide reduces proteinuria in experimental membranous nephropathy and protects against C5b-9-induced podocyte injury in vitro.
    Kidney international, 2010, Volume: 77, Issue:11

    Topics: Administration, Oral; Animals; Cell Line; Complement Membrane Attack Complex; Cytoprotection; Desmin; Disease Models, Animal; Diterpenes; Epoxy Compounds; Female; Glomerulonephritis, Membranous; Heymann Nephritis Antigenic Complex; Immunoglobulin G; Immunosuppressive Agents; Mice; NADPH Oxidases; p38 Mitogen-Activated Protein Kinases; Phenanthrenes; Podocytes; Proteinuria; Rabbits; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reactive Oxygen Species; rho GTP-Binding Proteins; rhoA GTP-Binding Protein; Signal Transduction; Tacrolimus; Time Factors

2010
Clinical outcomes in children with Henoch-Schönlein purpura nephritis grade IIIa or IIIb.
    Pediatric nephrology (Berlin, Germany), 2011, Volume: 26, Issue:7

    Topics: Adolescent; Biopsy; Chi-Square Distribution; Child; Child, Preschool; China; Diterpenes; Drug Therapy, Combination; Epoxy Compounds; Female; Hematuria; Humans; IgA Vasculitis; Immunosuppressive Agents; Male; Nephritis; Nephrotic Syndrome; Phenanthrenes; Prednisone; Proteinuria; Retrospective Studies; Risk Assessment; Risk Factors; Severity of Illness Index; Time Factors; Treatment Outcome

2011
[Preparation and toxicity of triptolide-loaded poly (D,L-lactic acid) nanoparticles].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2004, Volume: 39, Issue:7

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Urea Nitrogen; Delayed-Action Preparations; Diterpenes; Drug Carriers; Drug Delivery Systems; Epoxy Compounds; Lactic Acid; Male; Nanotechnology; Particle Size; Phenanthrenes; Polyesters; Polymers; Proteinuria; Rats; Rats, Wistar; Tripterygium

2004