triptolide has been researched along with Neoplasms in 36 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (2.78) | 18.2507 |
| 2000's | 4 (11.11) | 29.6817 |
| 2010's | 22 (61.11) | 24.3611 |
| 2020's | 9 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Buckton, LK; McAlpine, SR; McConnell, JR | 1 |
| Ahn, MR; Maruta, H | 1 |
| Emami, SA; Taleghani, A; Tayarani-Najaran, Z | 1 |
| Kinghorn, AD; Ren, Y | 1 |
| Hua, D; Wu, X | 1 |
| Cai, XJ; Chen, YH; Jin, J; Li, JM; Xu, YY; Yuan, Y; Zhang, RY | 1 |
| Dai, L; He, GN; Song, J | 1 |
| Deng, G; Guo, Q; Lin, P; Wang, S; Xia, X; Xu, R | 1 |
| Chen, L; Fu, CM; Li, J; Li, JX; Luo, RF; Luo, YY; Shi, JF; Zhang, JM | 1 |
| Datan, E; He, QL; Lin, GQ; Liu, JO; Minn, I; Pomper, MG; Romo, D; Tong, L; Yu, B; Zhao, Q | 1 |
| Dhanasekaran, DN; Han, Y; Jo, H; Kim, H; Kim, S; Kim, SJ; Lee, J; Song, YS; Wang, W; Yang, KM | 1 |
| Huang, SW; Lu, ST; Wu, B; Xu, HB; Zhang, LJ; Zhuo, RX | 1 |
| Sun, X; Yan, P | 1 |
| Liu, BW; Luan, ZH; Ren, JH; Wang, YH; Wei, YM; Xue, HQ | 1 |
| Wang, B; Wang, Y; Yang, X | 1 |
| Hua, ZC; Lin, Y; Lu, M; Yang, X; Zhang, J; Zheng, W; Zhuang, H | 1 |
| Ben Yebdri, F; Goulet, ML; Hiscott, J; Lin, R; Stojdl, DF; Tang, VA; Van Grevenynghe, J; Wu, JH | 1 |
| Bai, XY; Wang, CH; Wang, CY | 1 |
| Park, B | 1 |
| Al-Assaad, AS; Angagaw, MH; Ayers, M; Blanchard, R; Booher, RN; Dolinski, BM; Fawell, SE; Gilliland, G; Harmonay, L; Hatch, H; Hirsch, HA; Im, EK; Kondic, AG; Lee, J; Lennon, XQ; Loboda, A; Long, BJ; Mauro, D; Merkel, CE; Miselis, N; Monahan, JW; Nebozhyn, M; Nguyen, T; Pucci, V; Schuller, AG; Shi, B; Strack, P; Wang, Y; Zawel, L; Zhang, T | 1 |
| Fan, Y; Shan, Y; Wang, C; Xu, W; Xu, X; Yang, J; Zhuang, B | 1 |
| Chen, MW; Chen, Y; Cheng, KJ; Jiang, QW; Lv, M; Mei, XL; Qin, WM; Qiu, JG; Shi, Z; Wei, MN; Wei, X; Xue, YQ; Yang, Y; Zhang, WJ; Zhang, X; Zheng, DW | 1 |
| Datan, E; He, QL; Head, SA; Liu, JO; Minn, I; Pomper, MG; Wang, Q; Xu, P; Yu, B | 1 |
| Li, R; Shen, C; Tao, Y; Tian, X; Wang, F; Wang, Z; Zhang, Q; Zhang, X; Zhang, Y | 1 |
| Kapoor, S | 1 |
| Bunz, F | 1 |
| Liao, M; Luo, Y; Shi, C | 1 |
| Pan, J | 1 |
| Dou, QP; Liu, J; Yang, H | 1 |
| Chen, Y; Dai, M; Ding, J; Feng, JM; Jiang, Y; Li, YC; Li, Z; Luo, ZG; Miao, ZH; Tong, LJ; Yu, B; Zhou, ZL | 1 |
| Liu, Z; Ma, L; Zhou, GB | 1 |
| Cao, X; Chen, L; Jiang, F; Lin, B; Liu, J; Lu, N; Wang, G; Wu, H; Yan, T; Yan, X; Zeng, JZ; Zeng, W; Zhang, C; Zhang, XK; Zhou, H | 1 |
| Capranico, G; Ding, J; He, JX; Li, YC; Manzo, SG; Marinello, J; Miao, ZH; Wang, YQ; Zhou, ZL | 1 |
| Chen, X; Lang, L; Li, Y; Liu, X; Tang, K; Wang, C | 1 |
| Chang, W; Kao, PN; Lee, KY; Qiu, D; Rosen, GD | 1 |
| Anderson, E; Chang, WT; Gotmare, S; Kang, JJ; Lee, KY; Rosen, GD; Ross, JA; Wei, K | 1 |
16 review(s) available for triptolide and Neoplasms
| Article | Year |
|---|---|
Regulating the master regulator: Controlling heat shock factor 1 as a chemotherapy approach.
Topics: HSP90 Heat-Shock Proteins; Humans; Neoplasms; Transcription Factors | 2015 |
From bench (laboratory) to bed (hospital/home): How to explore effective natural and synthetic PAK1-blockers/longevity-promoters for cancer therapy.
Topics: Animals; Antineoplastic Agents; Click Chemistry; Drug Discovery; Humans; Longevity; Neoplasms; p21-Activated Kinases; Protein Kinase Inhibitors | 2017 |
Artemisia: a promising plant for the treatment of cancer.
Topics: Animals; Antineoplastic Agents, Phytogenic; Artemisia; Cell Proliferation; Humans; Molecular Structure; Neoplasms; Neoplasms, Experimental; Plant Extracts; Plants, Medicinal | 2020 |
Small-molecule inhibitors targeting small ubiquitin-like modifier pathway for the treatment of cancers and other diseases.
Topics: Humans; Neoplasms; Protein Processing, Post-Translational; Small Ubiquitin-Related Modifier Proteins; Sumoylation; Ubiquitin | 2022 |
A comprehensive review on celastrol, triptolide and triptonide: Insights on their pharmacological activity, toxicity, combination therapy, new dosage form and novel drug delivery routes.
Topics: Diterpenes; Epoxy Compounds; Humans; Neoplasms; Phenanthrenes; Triterpenes | 2023 |
[Research progress on anti-tumor effects and mechanisms of triptolide and its combined application].
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Cell Cycle Checkpoints; Diterpenes; Epoxy Compounds; Humans; Neoplasms; Phenanthrenes; Tripterygium | 2019 |
Triptolide: reflections on two decades of research and prospects for the future.
Topics: Animals; Autoimmune Diseases; Diterpenes; Drug Design; Drug Discovery; Epoxy Compounds; Forecasting; Humans; Inflammation; Neoplasms; Phenanthrenes; Tripterygium | 2021 |
Phytochemicals in Cancer Immune Checkpoint Inhibitor Therapy.
Topics: Animals; Antigens, CD; Antineoplastic Agents; B7 Antigens; B7-H1 Antigen; Camptothecin; CTLA-4 Antigen; Diterpenes; Epoxy Compounds; Flavonoids; Hepatitis A Virus Cellular Receptor 2; Humans; Immune Checkpoint Inhibitors; Immunotherapy; Isothiocyanates; Lymphocyte Activation Gene 3 Protein; Mice; Neoplasms; Phenanthrenes; Phytochemicals; Plant Extracts; Programmed Cell Death 1 Receptor; Receptors, Immunologic; Saponins; Sulfoxides; Terpenes; Tumor Microenvironment | 2021 |
Triptolide: A new star for treating human malignancies.
Topics: Antineoplastic Agents, Alkylating; Diterpenes; Epoxy Compounds; Humans; Neoplasms; Phenanthrenes; Prognosis | 2018 |
Triptolide, A Potential Autophagy Modulator.
Topics: Animals; Apoptosis; Autophagy; Diterpenes; Epoxy Compounds; Humans; Neoplasms; Neuroprotective Agents; Phenanthrenes; Podocytes | 2019 |
The Study of Cellular Mechanism of Triptolide in the Treatment of Cancer, Bone Loss and Cardiovascular Disease and Triptolide's Toxicity.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Arthritis, Rheumatoid; Autophagy; Cardiovascular Diseases; Diterpenes; Epoxy Compounds; Humans; Medicine, Chinese Traditional; Neoplasms; Osteoporosis; Phenanthrenes; Plant Extracts; Signal Transduction; Tripterygium | 2020 |
Traditional Chinese medicine: a treasured natural resource of anticancer drug research and development.
Topics: Alkaloids; Amphibian Venoms; Animals; Antineoplastic Agents, Phytogenic; Berberine; Diterpenes; Drug Combinations; Drug Discovery; Drugs, Chinese Herbal; Epoxy Compounds; Flavonoids; Humans; Matrines; Medicine, Chinese Traditional; Molecular Conformation; Molecular Targeted Therapy; Neoplasms; Phenanthrenes; Plants, Medicinal; Podophyllotoxin; Quinolizines | 2014 |
[Advance in the anti-tumor mechanism of triptolide].
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Diterpenes; Drugs, Chinese Herbal; Epoxy Compounds; Humans; Neoplasms; Phenanthrenes; Tripterygium | 2009 |
RNA polymerase - an important molecular target of triptolide in cancer cells.
Topics: Animals; Cell Division; Diterpenes; DNA-Directed RNA Polymerases; Epoxy Compounds; Humans; Neoplasms; Oncogenes; Phenanthrenes | 2010 |
Targeting tumor proteasome with traditional Chinese medicine.
Topics: Animals; Antineoplastic Agents, Phytogenic; Benzyl Compounds; Curcumin; Diterpenes; Drug Delivery Systems; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Epoxy Compounds; Humans; Medicine, Chinese Traditional; Molecular Structure; Naphthoquinones; Neoplasms; Pentacyclic Triterpenes; Phenanthrenes; Phenols; Proteasome Endopeptidase Complex; Signal Transduction; Triterpenes | 2010 |
The main anticancer bullets of the Chinese medicinal herb, thunder god vine.
Topics: Animals; Diterpenes; Drugs, Chinese Herbal; Epoxy Compounds; Humans; Neoplasms; Pentacyclic Triterpenes; Phenanthrenes; Signal Transduction; Tripterygium; Triterpenes | 2011 |
20 other study(ies) available for triptolide and Neoplasms
| Article | Year |
|---|---|
Development of Potential Antitumor Agents from the Scaffolds of Plant-Derived Terpenoid Lactones.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Biological Products; Diterpenes; Humans; Neoplasms; Sesquiterpenes; Structure-Activity Relationship; Triterpenes | 2020 |
Modulating tumour vascular normalisation using triptolide-loaded NGR-functionalized liposomes for enhanced cancer radiotherapy.
Topics: Animals; Cell Line, Tumor; Diterpenes; Drug Delivery Systems; Humans; Lipopolysaccharides; Liposomes; Mice; Neoplasms | 2023 |
Combination of ferroptosis and pyroptosis dual induction by triptolide nano-MOFs for immunotherapy of Melanoma.
Topics: Cell Line, Tumor; Ferroptosis; Humans; Immunotherapy; Lung Neoplasms; Melanoma; Metal-Organic Frameworks; Neoplasms; Pyroptosis; Reactive Oxygen Species | 2023 |
Codelivery of doxorubicin and triptolide with reduction-sensitive lipid-polymer hybrid nanoparticles for in vitro and in vivo synergistic cancer treatment.
Topics: Animals; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Diterpenes; Doxorubicin; Drug Delivery Systems; Drug Synergism; Epoxy Compounds; Flow Cytometry; Humans; Lactic Acid; Lipids; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Neoplasms; Oxidation-Reduction; Particle Size; Phenanthrenes; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2017 |
Herbal compound triptolide synergistically enhanced antitumor activity of vasostatin120-180.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Calreticulin; Cell Line; Cell Line, Tumor; Colorectal Neoplasms; Diterpenes; Drug Synergism; Drugs, Chinese Herbal; Epoxy Compounds; Ethnopharmacology; HCT116 Cells; Humans; Mice; Mice, Nude; Neoplasms; Neovascularization, Pathologic; Peptide Fragments; Phenanthrenes; Random Allocation; Recombinant Proteins; Tripterygium; Xenograft Model Antitumor Assays | 2013 |
Triptolide-mediated inhibition of interferon signaling enhances vesicular stomatitis virus-based oncolysis.
Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Cell Line, Tumor; Combined Modality Therapy; Diterpenes; Epoxy Compounds; Female; HEK293 Cells; Humans; Interferons; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Neoplasms, Experimental; Oncolytic Virotherapy; Oncolytic Viruses; Phenanthrenes; Signal Transduction; Vesicular stomatitis Indiana virus; Virus Replication; Xenograft Model Antitumor Assays | 2013 |
Triptolide, a diterpene, inhibits osteoclastogenesis, induced by RANKL signaling and human cancer cells.
Topics: Animals; Bone Resorption; Cell Differentiation; Cell Line, Tumor; Diterpenes; Epoxy Compounds; Humans; Mice; Neoplasms; Osteoclasts; Osteoporosis; Phenanthrenes; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Signal Transduction | 2014 |
MCL1 and BCL-xL levels in solid tumors are predictive of dinaciclib-induced apoptosis.
Topics: Aniline Compounds; Animals; Antineoplastic Agents; Apoptosis; bcl-X Protein; Bridged Bicyclo Compounds, Heterocyclic; Cell Cycle Checkpoints; Cell Line, Tumor; Cyclic N-Oxides; Disease Models, Animal; Diterpenes; Drug Resistance, Neoplasm; Drug Synergism; Epoxy Compounds; Female; Gene Dosage; Humans; Indolizines; Male; Mice; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasms; Phenanthrenes; Pyridinium Compounds; RNA, Messenger; Sulfonamides; Xenograft Model Antitumor Assays | 2014 |
Inhibition of Cancer Angiogenesis Using Triptolide Nanoparticles.
Topics: Animals; Antineoplastic Agents, Alkylating; Cells, Cultured; Diterpenes; Drug Carriers; Epoxy Compounds; Human Umbilical Vein Endothelial Cells; Humans; Male; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Nanoparticles; Neoplasms; Neovascularization, Pathologic; Phenanthrenes; Rats; Rats, Sprague-Dawley | 2015 |
Synergistic anticancer effects of triptolide and celastrol, two main compounds from thunder god vine.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Proliferation; Diterpenes; Dose-Response Relationship, Drug; Drug Synergism; Epoxy Compounds; G2 Phase Cell Cycle Checkpoints; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Humans; Inhibitory Concentration 50; Mice, Inbred BALB C; Mice, Nude; Molecular Chaperones; Neoplasms; Pentacyclic Triterpenes; Phenanthrenes; Phytotherapy; Plant Extracts; Plants, Medicinal; Reactive Oxygen Species; Time Factors; Transfection; Tripterygium; Triterpenes; Tumor Burden; Xenograft Model Antitumor Assays | 2015 |
Targeted Delivery and Sustained Antitumor Activity of Triptolide through Glucose Conjugation.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Diterpenes; Drug Delivery Systems; Epoxy Compounds; Glucose; HEK293 Cells; Humans; Mice; Neoplasms; Phenanthrenes | 2016 |
Triptolide inhibits tumor growth by induction of cellular senescence.
Topics: Animals; Cell Proliferation; Cellular Senescence; Diterpenes; Epoxy Compounds; Hep G2 Cells; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Phenanthrenes; Signal Transduction; Up-Regulation; Xenograft Model Antitumor Assays | 2017 |
Triptolide and management of systemic malignancies besides pancreatic carcinomas.
Topics: Anti-Inflammatory Agents, Non-Steroidal; bcl-2-Associated X Protein; Cell Division; Diterpenes; Epoxy Compounds; Humans; Neoplasms; Pancreatic Neoplasms; Phenanthrenes; Up-Regulation | 2009 |
Ancient drugs, modern targets.
Topics: ADAM Proteins; ADAM10 Protein; Amyloid Precursor Protein Secretases; Antineoplastic Agents, Alkylating; Diterpenes; Drug Discovery; Drugs, Chinese Herbal; Epoxy Compounds; Humans; Membrane Proteins; Neoplasms; Phenanthrenes | 2009 |
Increased accumulation of hypoxia-inducible factor-1α with reduced transcriptional activity mediates the antitumor effect of triptolide.
Topics: Antineoplastic Agents; Blotting, Western; Cell Line, Tumor; Cell Survival; Diterpenes; Enzyme-Linked Immunosorbent Assay; Epoxy Compounds; Flow Cytometry; Fluorescent Antibody Technique; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunoprecipitation; Neoplasms; Phenanthrenes; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Vascular Endothelial Growth Factors | 2010 |
Antagonist effect of triptolide on AKT activation by truncated retinoid X receptor-alpha.
Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Caspase 8; Caspase 9; Cell Line; Cell Line, Tumor; Diterpenes; Drugs, Chinese Herbal; Enzyme Activation; Epoxy Compounds; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Phenanthrenes; Proto-Oncogene Proteins c-akt; Retinoid X Receptor alpha; Signal Transduction; Tumor Necrosis Factor-alpha | 2012 |
Natural product triptolide mediates cancer cell death by triggering CDK7-dependent degradation of RNA polymerase II.
Topics: Base Sequence; Biological Products; Cell Death; Cell Line, Tumor; Chromatin Immunoprecipitation; Cyclin-Dependent Kinase-Activating Kinase; Cyclin-Dependent Kinases; Diterpenes; DNA Primers; Epoxy Compounds; Humans; Neoplasms; Phenanthrenes; Phosphorylation; Proteolysis; Reverse Transcriptase Polymerase Chain Reaction; RNA Polymerase II | 2012 |
[Identification of two small molecule inhibitors of hypoxia-inducible factor 1 with different cell-based screening model].
Topics: Cell Line, Tumor; Cell Proliferation; Diterpenes; Drug Evaluation, Preclinical; Epoxy Compounds; Humans; Hypoxia-Inducible Factor 1; Lignans; Luciferases; Models, Biological; Neoplasms; Phenanthrenes | 2012 |
PG490 (triptolide) cooperates with tumor necrosis factor-alpha to induce apoptosis in tumor cells.
Topics: Antineoplastic Agents, Alkylating; Apoptosis; Base Sequence; Diterpenes; DNA Primers; Drug Synergism; Epoxy Compounds; Humans; Inhibitor of Apoptosis Proteins; Neoplasms; NF-kappa B; Phenanthrenes; Protein Biosynthesis; Proteins; Transcriptional Activation; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Ubiquitin-Protein Ligases | 1999 |
Triptolide and chemotherapy cooperate in tumor cell apoptosis. A role for the p53 pathway.
Topics: Animals; Antineoplastic Agents; Apoptosis; Base Sequence; Cell Cycle; Diterpenes; DNA Primers; DNA, Neoplasm; Doxorubicin; Drug Synergism; Epoxy Compounds; Humans; Mice; Neoplasms; Oncogene Protein p21(ras); Phenanthrenes; Protein Binding; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2001 |