Compounds > triptolide
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triptolide and Liver Neoplasms

triptolide has been researched along with Liver Neoplasms in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's10 (62.50)24.3611
2020's6 (37.50)2.80

Authors

AuthorsStudies
Kong, F; Liu, S; Liu, X; Miao, X; Pei, D; Zheng, Y1
Gong, C; Han, L; Li, Z; Wang, R; Yang, G; Yuan, Y1
Chen, Z; Liu, W; Wang, J; Wu, S; Yang, Y1
Huang, X; Jiang, Z; Miao, Y; Nong, C; Tang, Q; Wang, J; Yu, Q; Yuan, Z; Zhang, H; Zhang, L; Zhu, Y1
Cai, Y; Chen, J; Huang, Y; Leung, GP; Li, J; Seto, SW; Wu, Y; Xu, Z; Zhang, J1
Gong, C; Li, Z; Wang, J; Wang, R; Wang, Y; Yang, G; Yang, M; Yuan, Y1
Chen, Z; Li, SG; Ling, CQ; Miao, YQ; Qin, LP; Qin, WX; Shi, QW; Wang, Y; Yuan, LY1
Guo, QY; Li, WJ; Liao, MM; Lin, N; Mao, X; Mi, GJ; Shen, Y; Wang, XY; Webster, TJ; You, C; Zhang, YQ1
Banerjee, S; Chen, Z; Dudeja, V; Li, X; Mackenzie, T; Saluja, AK; Sangwan, V; Vickers, SM; Wang, H1
Hu, S; Li, Y1
Alsaied, OA; Banerjee, S; Chugh, R; Jensen, EH; Krosch, TC; Saluja, A; Sangwan, V; Vickers, SM1
Hackett, MJ; Hui, KM; Hyeon, T; Ling, D; Na, K; Park, W; Song, C; Xia, H1
Banerjee, S; Saluja, A1
Liu, C; Ma, D; Wang, C; Wang, H; Zhao, S1
Dong, Z; Han, L; Ju, Y; Pan, X; Wang, G; Wang, M; Zhou, Y1
Chen, XH; Ji, YC; Ma, R; Sun, YY; Wang, D; Xiao, L; Yang, YP1

Reviews

1 review(s) available for triptolide and Liver Neoplasms

ArticleYear
Minnelide, a novel drug for pancreatic and liver cancer.
    Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2015, Volume: 15, Issue:4 Suppl

    Topics: Animals; Antineoplastic Agents, Alkylating; Diterpenes; Epoxy Compounds; Humans; Liver Neoplasms; Organophosphates; Pancreatic Neoplasms; Phenanthrenes; Prodrugs

2015

Other Studies

15 other study(ies) available for triptolide and Liver Neoplasms

ArticleYear
Membrane protein-chimeric liposome-mediated delivery of triptolide for targeted hepatocellular carcinoma therapy.
    Drug delivery, 2021, Volume: 28, Issue:1

    Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chemistry, Pharmaceutical; Diterpenes; Drug Carriers; Epoxy Compounds; Humans; Liposomes; Liver Neoplasms; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Particle Size; Phenanthrenes; Random Allocation; Signal Transduction; Surface Properties

2021
Sorafenib and triptolide loaded cancer cell-platelet hybrid membrane-camouflaged liquid crystalline lipid nanoparticles for the treatment of hepatocellular carcinoma.
    Journal of nanobiotechnology, 2021, Nov-08, Volume: 19, Issue:1

    Topics: Animals; Antineoplastic Agents; Apoptosis; Biomimetic Materials; Blood Platelets; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Membrane; Diterpenes; Epoxy Compounds; Humans; Liposomes; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Nanomedicine; Nanoparticles; Phenanthrenes; RAW 264.7 Cells; Sorafenib

2021
Triptolide-mediated downregulation of FLIP
    Medical oncology (Northwood, London, England), 2022, Oct-29, Volume: 40, Issue:1

    Topics: Apoptosis; Carcinoma, Hepatocellular; Caspase 8; Cell Line, Tumor; Diterpenes; Down-Regulation; Humans; Liver Neoplasms; Proteasome Endopeptidase Complex; Receptors, Death Domain; Tumor Necrosis Factor-alpha

2022
Triptolide leads to hepatic intolerance to exogenous lipopolysaccharide and natural-killer-cell mediated hepatocellular damage by inhibiting MHC class I molecules.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2023, Volume: 109

    Topics: Animals; Carcinoma, Hepatocellular; Diterpenes; Histocompatibility Antigens Class I; Killer Cells, Natural; Lipopolysaccharides; Liver Neoplasms; Mice; Mice, Inbred C57BL; Phenanthrenes

2023
Glycyrrhizic Acid-Lipid Framework Nanovehicle Loading Triptolide for Combined Immunochemotherapy.
    ACS applied materials & interfaces, 2023, Sep-06, Volume: 15, Issue:35

    Topics: Carcinoma, Hepatocellular; Glycyrrhizic Acid; Humans; Lipids; Liposomes; Liver Neoplasms

2023
γ-Cyclodextrin metal-organic framework as a carrier to deliver triptolide for the treatment of hepatocellular carcinoma.
    Drug delivery and translational research, 2022, Volume: 12, Issue:5

    Topics: Carcinoma, Hepatocellular; Diterpenes; Drug Carriers; Epoxy Compounds; Excipients; gamma-Cyclodextrins; Humans; Liver Neoplasms; Metal-Organic Frameworks; Phenanthrenes

2022
C-Myc-dependent repression of two oncogenic miRNA clusters contributes to triptolide-induced cell death in hepatocellular carcinoma cells.
    Journal of experimental & clinical cancer research : CR, 2018, Mar-09, Volume: 37, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Carcinoma, Hepatocellular; Cell Death; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Diterpenes; DNA Helicases; DNA-Binding Proteins; Epoxy Compounds; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Mice; MicroRNAs; Oncogenes; Phenanthrenes; Proto-Oncogene Proteins c-myc; RNA Interference; Xenograft Model Antitumor Assays

2018
Galactosylated chitosan triptolide nanoparticles for overcoming hepatocellular carcinoma: Enhanced therapeutic efficacy, low toxicity, and validated network regulatory mechanisms.
    Nanomedicine : nanotechnology, biology, and medicine, 2019, Volume: 15, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Carcinoma, Hepatocellular; Cell Proliferation; Chitosan; Diterpenes; Epoxy Compounds; Galactose; Humans; Liver Neoplasms; Male; Mice; Mice, Nude; Nanoparticles; Phenanthrenes; Reproduction; Signal Transduction; Tissue Distribution; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2019
miR-204 mediated loss of Myeloid cell leukemia-1 results in pancreatic cancer cell death.
    Molecular cancer, 2013, Sep-11, Volume: 12, Issue:1

    Topics: 3' Untranslated Regions; Animals; Antineoplastic Agents; Base Sequence; Binding Sites; Cell Death; Cell Line, Tumor; Diterpenes; Epithelium; Epoxy Compounds; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Mice; Mice, SCID; MicroRNAs; Myeloid Cell Leukemia Sequence 1 Protein; Organophosphates; Pancreatic Ducts; Pancreatic Neoplasms; Phenanthrenes; RNA Interference; Up-Regulation; Xenograft Model Antitumor Assays

2013
Triptolide sensitizes liver cancer cell lines to chemotherapy in vitro and in vivo.
    Panminerva medica, 2014, Volume: 56, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cell Line, Tumor; Cell Survival; Diterpenes; Dose-Response Relationship, Drug; Drug Synergism; Drugs, Chinese Herbal; Epoxy Compounds; Female; Flow Cytometry; Fluorouracil; Hep G2 Cells; Humans; Liver Neoplasms; Mice; Mice, Nude; Oxidative Stress; Phenanthrenes; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Tripterygium

2014
Sorafenib and triptolide as combination therapy for hepatocellular carcinoma.
    Surgery, 2014, Volume: 156, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Caspase 7; Cell Line, Tumor; Cell Proliferation; Cell Survival; Diterpenes; Drug Synergism; Epoxy Compounds; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Mice; Mice, Nude; Models, Biological; NF-kappa B p50 Subunit; Niacinamide; Organophosphates; Phenanthrenes; Phenylurea Compounds; Prodrugs; Signal Transduction; Sincalide; Sorafenib; Translational Research, Biomedical; Xenograft Model Antitumor Assays

2014
pH-sensitive nanoformulated triptolide as a targeted therapeutic strategy for hepatocellular carcinoma.
    ACS nano, 2014, Aug-26, Volume: 8, Issue:8

    Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Chemistry, Pharmaceutical; Diterpenes; Down-Regulation; Drug Liberation; Epoxy Compounds; Folic Acid; Humans; Hydrogen-Ion Concentration; Liver Neoplasms; Mice; Molecular Targeted Therapy; Nanostructures; Phenanthrenes; Survival Analysis; Xenograft Model Antitumor Assays

2014
Triptolide Inhibits Invasion and Tumorigenesis of Hepatocellular Carcinoma MHCC-97H Cells Through NF-κB Signaling.
    Medical science monitor : international medical journal of experimental and clinical research, 2016, May-30, Volume: 22

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Carcinogenesis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Diterpenes; Epoxy Compounds; Female; Humans; Liver Neoplasms; Matrix Metalloproteinase 9; Mice; Mice, Inbred BALB C; NF-kappa B; Phenanthrenes; Random Allocation; Signal Transduction; Xenograft Model Antitumor Assays

2016
[Combination of triptolide with sodium cantharidinate synergistically enhances apoptosis on
 hepatoma cell line 7721].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2016, Sep-28, Volume: 41, Issue:9

    Topics: Apoptosis; Cantharidin; Carcinoma, Hepatocellular; Caspase 3; Cell Line, Tumor; Diterpenes; Down-Regulation; Drug Therapy, Combination; Epoxy Compounds; Humans; Liver Neoplasms; NF-kappa B; Phenanthrenes; Transcription Factor RelA

2016
Triptolide inhibits viability and induces apoptosis in liver cancer cells through activation of the tumor suppressor gene p53.
    International journal of oncology, 2017, Volume: 50, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cell Survival; Diterpenes; DNA Damage; DNA-Binding Proteins; Enzyme Activation; Epoxy Compounds; Hep G2 Cells; Humans; Liver Neoplasms; Phenanthrenes; Phosphorylation; RNA Interference; RNA, Small Interfering; Tumor Suppressor Protein p53

2017