Page last updated: 2024-09-02

triptolide and Leukemia

triptolide has been researched along with Leukemia in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (25.00)29.6817
2010's5 (62.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Almlöf, I; Artursson, P; Baranczewski, P; Burgos Morón, E; Calderón-Montaño, JM; Cazares-Körner, C; Darabi, M; Desroses, M; Fayezi, S; Ghassemian, A; Helleday, T; Höglund, A; Homan, E; Jemth, AS; Jenmalm Jensen, A; Koolmeister, T; Llona-Minguez, S; Loseva, O; Lundbäck, T; Mateus, A; Mehdizadeh, A; Sanjiv, K; Scobie, M; Sigmundsson, K; Valerie, NCK; Warpman Berglund, U; Wiita, E1
Chen, S; Huang, K; Lin, G; Wu, X1
Chen, J; Gao, N; Hu, X; Jin, Z; Li, G; Li, Q; Liu, L; Zhang, L; Zhou, J; Zhou, T1
Feng, Y; Liu, S; Lu, X; Su, X; Zhang, D; Zhang, Q; Zhong, L1
Chan, SF; Chen, YY; Chung, JG; Ko, YC; Kuo, CL; Liao, CL; Lin, JJ; Liu, KC; Tang, NY1
Aggarwal, BB; Chaturvedi, MM; Park, B; Sung, B; Yadav, VR1
Andreeff, M; Carter, BZ; Estrov, Z; Evans, RL; Harris, D; Mak, DH; McQueen, T; Schober, WD1
Jin, J; Lou, Y; Tong, X; Yao, H; Zheng, S; Zhu, L1

Other Studies

8 other study(ies) available for triptolide and Leukemia

ArticleYear
Piperazin-1-ylpyridazine Derivatives Are a Novel Class of Human dCTP Pyrophosphatase 1 Inhibitors.
    Journal of medicinal chemistry, 2017, 05-25, Volume: 60, Issue:10

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Enzyme Inhibitors; Humans; Leukemia; Molecular Docking Simulation; Piperazines; Pyridazines; Pyrophosphatases

2017
Triptolide promotes ferroptosis by suppressing Nrf2 to overcome leukemia cell resistance to doxorubicin.
    Molecular medicine reports, 2023, Volume: 27, Issue:1

    Topics: Doxorubicin; Ferroptosis; Humans; Leukemia; Lipids; NF-E2-Related Factor 2; Reactive Oxygen Species

2023
Triptolide induces apoptosis in human leukemia cells through caspase-3-mediated ROCK1 activation and MLC phosphorylation.
    Cell death & disease, 2013, Dec-05, Volume: 4

    Topics: Animals; Apoptosis; Caspase 3; Cell Line, Tumor; Diterpenes; Epoxy Compounds; Fluorescent Antibody Technique; HL-60 Cells; Humans; Immunoblotting; Leukemia; Membrane Potential, Mitochondrial; Mice; Mice, Nude; Phenanthrenes; Phosphorylation; rho-Associated Kinases; rhoA GTP-Binding Protein

2013
Raman spectrum reveals the cell cycle arrest of Triptolide-induced leukemic T-lymphocytes apoptosis.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2015, Apr-15, Volume: 141

    Topics: Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Shape; Cell Survival; Diterpenes; Epoxy Compounds; Humans; Jurkat Cells; Leukemia; Phenanthrenes; Principal Component Analysis; Spectrum Analysis, Raman; T-Lymphocytes

2015
Triptolide induced cell death through apoptosis and autophagy in murine leukemia WEHI-3 cells in vitro and promoting immune responses in WEHI-3 generated leukemia mice in vivo.
    Environmental toxicology, 2017, Volume: 32, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; B-Lymphocytes; Caspase 3; Caspase 8; Caspase 9; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cytochromes c; Diterpenes; DNA Damage; Endoplasmic Reticulum Chaperone BiP; Epoxy Compounds; Leukemia; Lymphocyte Activation; Macrophages; Male; Medicine, Chinese Traditional; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Microscopy, Confocal; Phenanthrenes; Reactive Oxygen Species; Spleen; T-Lymphocytes; Transplantation, Homologous

2017
Triptolide, histone acetyltransferase inhibitor, suppresses growth and chemosensitizes leukemic cells through inhibition of gene expression regulated by TNF-TNFR1-TRADD-TRAF2-NIK-TAK1-IKK pathway.
    Biochemical pharmacology, 2011, Nov-01, Volume: 82, Issue:9

    Topics: Antineoplastic Agents; Cell Line; Cell Proliferation; Diterpenes; Enzyme Inhibitors; Epoxy Compounds; Gene Expression Regulation, Neoplastic; Histone Acetyltransferases; Humans; Inflammation; Leukemia; Molecular Structure; Neoplasm Invasiveness; Neoplasm Metastasis; NF-kappa B; Paclitaxel; Phenanthrenes; Signal Transduction; Thalidomide; Tumor Necrosis Factor-alpha

2011
Triptolide induces caspase-dependent cell death mediated via the mitochondrial pathway in leukemic cells.
    Blood, 2006, Jul-15, Volume: 108, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Apoptosis Regulatory Proteins; Caspase 8; Caspase 9; Caspases; Cell Line, Tumor; Diterpenes; Epoxy Compounds; Humans; Leukemia; Mitochondria; Phenanthrenes; X-Linked Inhibitor of Apoptosis Protein

2006
Triptolide inhibits cyclooxygenase-2 and inducible nitric oxide synthase expression in human colon cancer and leukemia cells.
    Acta biochimica et biophysica Sinica, 2007, Volume: 39, Issue:2

    Topics: Base Sequence; Cell Line, Tumor; Cell Survival; China; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diterpenes; DNA Primers; Epoxy Compounds; Humans; K562 Cells; Leukemia; Medicine, Chinese Traditional; Nitric Oxide Synthase Type II; Phenanthrenes; RNA, Messenger; Transcription, Genetic

2007