Page last updated: 2024-09-02

triptolide and Glioma

triptolide has been researched along with Glioma in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's5 (71.43)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Chen, Y; Feng, H; Li, Y; Tang, H; Xu, H1
Larion, M; Liu, Y; Ruiz-Rodado, V; Xu, G; Yang, C; Yu, D; Zhou, Y1
Yu, JS; Zhang, L1
Chen, YS; Chen, ZP; Guan, S; Guo, CC; Li, WP; Li, WY; Mou, YG; Sai, K; Wang, J; Yang, QY1
Chen, LT; Kao, CA; Lo, YC; So, EC; Wu, SN1
Chen, J; Hu, J; Li, J; Lin, Y; Qiu, P; Su, X; Wang, Y; Wu, S; Yan, G; Zhang, H; Zhang, J; Zhao, S; Zhou, Y; Zhu, W1
Huang, YL; Sun, CF; Xu, QN; Ye, M; Zhou, D; Zhou, YX1

Other Studies

7 other study(ies) available for triptolide and Glioma

ArticleYear
Semisynthesis of triptolide analogues: effect of B-ring substituents on cytotoxic activities.
    Bioorganic & medicinal chemistry letters, 2014, Dec-15, Volume: 24, Issue:24

    Topics: Antineoplastic Agents; Cell Proliferation; Diterpenes; Drug Screening Assays, Antitumor; Epoxy Compounds; Glioma; Humans; Male; Models, Molecular; Molecular Structure; Organic Chemicals; Phenanthrenes; Prostatic Neoplasms; Structure-Activity Relationship; Tumor Cells, Cultured

2014
Triptolide suppresses IDH1-mutated malignancy via Nrf2-driven glutathione metabolism.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 05-05, Volume: 117, Issue:18

    Topics: Amino Acid Transport System y+; Animals; Biosynthetic Pathways; Cell Line, Tumor; Diterpenes; Epoxy Compounds; Gene Expression Regulation, Neoplastic; Glioma; Glutamate-Cysteine Ligase; Glutathione; Humans; Isocitrate Dehydrogenase; Mice; Mutation; NF-E2-Related Factor 2; Phenanthrenes; Reactive Oxygen Species; Synthetic Lethal Mutations; Xenograft Model Antitumor Assays

2020
Triptolide reverses helper T cell inhibition and down-regulates IFN-γ induced PD-L1 expression in glioma cell lines.
    Journal of neuro-oncology, 2019, Volume: 143, Issue:3

    Topics: Antineoplastic Agents, Alkylating; B7-H1 Antigen; CD4-Positive T-Lymphocytes; Coculture Techniques; Diterpenes; Down-Regulation; Epoxy Compounds; Gene Expression Regulation, Neoplastic; Glioma; Humans; Interferon-gamma; Phenanthrenes; T-Lymphocytes, Helper-Inducer; Tumor Cells, Cultured

2019
Triptolide synergistically enhances temozolomide-induced apoptosis and potentiates inhibition of NF-κB signaling in glioma initiating cells.
    The American journal of Chinese medicine, 2014, Volume: 42, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Cell Line, Tumor; Cell Transformation, Neoplastic; Dacarbazine; Disease Models, Animal; Diterpenes; Drug Synergism; Epoxy Compounds; Glioma; Humans; Mice; Neoplasm Transplantation; NF-kappa B; Phenanthrenes; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Stimulation, Chemical; Temozolomide; Transcription, Genetic; X-Linked Inhibitor of Apoptosis Protein

2014
High effectiveness of triptolide, an active diterpenoid triepoxide, in suppressing Kir-channel currents from human glioma cells.
    European journal of pharmacology, 2014, Sep-05, Volume: 738

    Topics: Cell Line, Tumor; Diterpenes; Electrophysiological Phenomena; Epoxy Compounds; Gene Expression Regulation; Glioma; Humans; Kinetics; Membrane Potentials; Phenanthrenes; Potassium; Potassium Channels, Inwardly Rectifying; RNA, Messenger; Scorpion Venoms

2014
Triptolide inhibits proliferation and invasion of malignant glioma cells.
    Journal of neuro-oncology, 2012, Volume: 109, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain Neoplasms; cdc42 GTP-Binding Protein; Cell Cycle; Cell Movement; Cell Proliferation; Cyclin-Dependent Kinases; Diterpenes; Epoxy Compounds; Female; Flow Cytometry; Glioma; Mice; Mice, Nude; Neoplasm Invasiveness; Phenanthrenes; rac GTP-Binding Proteins; rac1 GTP-Binding Protein; RAC2 GTP-Binding Protein; Rats; Retinoblastoma Protein; Tumor Cells, Cultured

2012
[Several monomes from Tripterygium wilfordii inhibit proliferation of glioma cells in vitro].
    Ai zheng = Aizheng = Chinese journal of cancer, 2002, Volume: 21, Issue:10

    Topics: Antineoplastic Agents; Cell Division; Diterpenes; Epoxy Compounds; Glioma; Humans; Inhibitory Concentration 50; Molecular Structure; Pentacyclic Triterpenes; Phenanthrenes; Plant Extracts; Tripterygium; Triterpenes; Tumor Cells, Cultured

2002