triptolide has been researched along with Diabetic Glomerulosclerosis in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (6.25) | 29.6817 |
| 2010's | 9 (56.25) | 24.3611 |
| 2020's | 6 (37.50) | 2.80 |
| Authors | Studies |
|---|---|
| Gu, D; Pang, R | 1 |
| An, X; Fan, D; Tian, R; Yan, M; Yin, Z; Zhang, J; Zhou, Y | 1 |
| Gao, J; Liang, Z; Liu, X; Ma, N; Zhao, F | 1 |
| Gao, Y; Guo, Z; Liu, Y | 1 |
| Cai, BL; Huang, F; Lin, N; Mao, X; Su, XH; Wang, JR; Wang, KX; Wu, AG; Zhang, YG | 1 |
| An, X; Fan, D; Li, Y; Qian, Q; Wang, P; Yan, M; Yang, Y; Ying, Z | 1 |
| Fang, QJ; Liu, BH; Liu, YL; Sun, W; Tu, Y; Wan, YG; Wan, ZY; Wang, WW; Wu, W; Yee, HY; Yuan, CC | 1 |
| Chang, B; Chang, Y; Chen, L; Han, F; Han, Z; Li, C; Sun, B; Wang, S; Yang, J | 1 |
| Chang, Y; Chen, L; Han, F; Li, X; Sun, B; Xue, M; Yang, Y | 1 |
| Chang, Y; Chen, L; Cheng, Y; Han, F; Li, X; Lu, Y; Sun, B; Xue, M; Yang, Y | 1 |
| Hong, YZ; Wang, BF; Yang, XC; Zhu, JJ | 1 |
| Chang, B; Chen, L; Guo, H; Guo, J; Liu, H; Pan, C; Wu, X; Zhou, Y; Zhu, Z | 1 |
| An, ZM; Dong, XG; Guo, Y; Qin, T; Zhou, JL | 1 |
| Gao, Q; Liu, Z; Qin, W; Shen, W; Wang, J; Wang, S; Zeng, C; Zhang, M; Zheng, C; Zhu, X | 1 |
| Li, YS; Liu, LQ; Ma, RX; Xu, Y; Zhang, J | 1 |
| Chen, W; Gong, J; Song, HX | 1 |
1 review(s) available for triptolide and Diabetic Glomerulosclerosis
| Article | Year |
|---|---|
Analysis of the potential molecular biology of triptolide in the treatment of diabetic nephropathy: A narrative review.
Topics: Diabetes Mellitus; Diabetic Nephropathies; Humans; Molecular Biology; Molecular Docking Simulation; Phenanthrenes | 2022 |
1 trial(s) available for triptolide and Diabetic Glomerulosclerosis
| Article | Year |
|---|---|
[Effect of triptolide on urinary monocyte chemottractant protein-1 in patients with diabetic nephropathy].
Topics: Adult; Aged; Chemokine CCL2; Diabetic Nephropathies; Diterpenes; Epoxy Compounds; Female; Humans; Immunosuppressive Agents; Male; Middle Aged; Phenanthrenes; Phytotherapy; Prospective Studies | 2005 |
14 other study(ies) available for triptolide and Diabetic Glomerulosclerosis
| Article | Year |
|---|---|
Triptolide Improves Renal Injury in Diabetic Nephropathy Rats through TGF-β1/Smads Signal Pathway.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Diterpenes; Epoxy Compounds; Kidney; Male; Phenanthrenes; Rats; Rats, Sprague-Dawley; Signal Transduction; Smad Proteins; Transforming Growth Factor beta1 | 2021 |
Prediction of the Potential Mechanism of Triptolide in Improving Diabetic Nephropathy by Utilizing A Network Pharmacology and Molecular Docking Approach.
Topics: Diabetes Mellitus; Diabetic Nephropathies; Diterpenes; Drugs, Chinese Herbal; Epoxy Compounds; Female; Humans; Male; Molecular Docking Simulation; Network Pharmacology; Phenanthrenes | 2022 |
Triptolide inhibits oxidative stress and inflammation via the microRNA-155-5p/brain-derived neurotrophic factor to reduce podocyte injury in mice with diabetic nephropathy.
Topics: Animals; Apoptosis; Brain-Derived Neurotrophic Factor; Diabetes Mellitus; Diabetic Nephropathies; Diterpenes; Epoxy Compounds; Glucose; Inflammation; Irbesartan; Mice; MicroRNAs; Oxidative Stress; Phenanthrenes; Podocytes | 2022 |
[In vitro "benefit-risk" evaluation and network regulation mechanism of Colquhounia Root Tablets and its key material basis].
Topics: Animals; Arthritis, Rheumatoid; Cytokines; Diabetic Nephropathies; Drugs, Chinese Herbal; Glomerulonephritis, Membranous; Humans; Mice; Molecular Docking Simulation; Tablets | 2022 |
Deciphering the anti-renal fibrosis mechanism of triptolide in diabetic nephropathy by the integrative approach of network pharmacology and experimental verification.
Topics: Diabetes Mellitus; Diabetic Nephropathies; Diterpenes; Fibrosis; Humans; Network Pharmacology | 2023 |
[Triptolide inhibits NLRP3 inflammasome activation and ameliorates podocyte epithelial-mesenchymal transition induced by high glucose].
Topics: Animals; Caspase 1; Cells, Cultured; Diabetic Nephropathies; Diterpenes; Epithelial-Mesenchymal Transition; Epoxy Compounds; Glucose; Inflammasomes; Interleukin-18; Interleukin-1beta; Mice; NLR Family, Pyrin Domain-Containing 3 Protein; Phenanthrenes; Podocytes | 2019 |
Triptolide prevents extracellular matrix accumulation in experimental diabetic kidney disease by targeting microRNA-137/Notch1 pathway.
Topics: Albuminuria; Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Diet, High-Fat; Diterpenes; Epoxy Compounds; Extracellular Matrix; Gene Expression Regulation; Humans; Kidney; Male; Mesangial Cells; MicroRNAs; Phenanthrenes; Rats, Sprague-Dawley; Receptor, Notch1; Renal Agents; Signal Transduction; Streptozocin; Transfection | 2018 |
Triptolide Suppresses Glomerular Mesangial Cell Proliferation in Diabetic Nephropathy Is Associated with Inhibition of PDK1/Akt/mTOR Pathway.
Topics: Animals; Blotting, Western; Cell Cycle; Cell Proliferation; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Diet, High-Fat; Diterpenes; Epoxy Compounds; Flow Cytometry; Humans; Male; Mesangial Cells; Pentanoic Acids; Phenanthrenes; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction; Streptozocin; TOR Serine-Threonine Kinases | 2017 |
Triptolide Attenuates Renal Tubular Epithelial-mesenchymal Transition Via the MiR-188-5p-mediated PI3K/AKT Pathway in Diabetic Kidney Disease.
Topics: Animals; Cell Line; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Diterpenes; Epithelial-Mesenchymal Transition; Epoxy Compounds; Humans; Male; MicroRNAs; Phenanthrenes; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Rats; Rats, Sprague-Dawley; Signal Transduction | 2018 |
[Effect of triptolide on the expression of RANTES in the renal tissue of diabetic nephropathy rats].
Topics: Animals; Chemokine CCL5; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Diterpenes; Drugs, Chinese Herbal; Epoxy Compounds; Glycated Hemoglobin; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Glomerulus; Kidney Tubules; Phenanthrenes; Rats; RNA, Messenger | 2014 |
Triptolide Improves Diabetic Nephropathy by Regulating Th Cell Balance and Macrophage Infiltration in Rat Models of Diabetic Nephropathy.
Topics: Animals; Diabetic Nephropathies; Disease Models, Animal; Diterpenes; Epoxy Compounds; Immunosuppressive Agents; Macrophages; Male; Phenanthrenes; Rats; Rats, Sprague-Dawley; Th1 Cells; Th2 Cells | 2016 |
Effect of triptolide on expression of oxidative carbonyl protein in renal cortex of rats with diabetic nephropathy.
Topics: Animals; Blood Glucose; Diabetic Nephropathies; Disease Models, Animal; Diterpenes; Drugs, Chinese Herbal; Epoxy Compounds; Gene Expression Regulation; Humans; Kidney Cortex; Oxidative Stress; Phenanthrenes; Protein Carbonylation; Proteins; Random Allocation; Rats; Rats, Sprague-Dawley; Streptozocin; Superoxide Dismutase | 2017 |
Treatment of db/db diabetic mice with triptolide: a novel therapy for diabetic nephropathy.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Glucose; Body Weight; Chemokine CCL2; Desmin; Diabetic Nephropathies; Diterpenes; Epoxy Compounds; Glomerular Filtration Rate; Immunohistochemistry; Kidney; Lipids; Liver; Mice; Mice, Inbred C57BL; Microscopy, Electron; Phenanthrenes; Podocytes; Reactive Oxygen Species; T-Lymphocytes; Tetrazoles; Valine; Valsartan | 2010 |
[Triptolide combined with irbesartan synergistically blocks podocyte injury in a type 2 diabetes rat model].
Topics: Animals; Biphenyl Compounds; Bone Morphogenetic Protein 7; Connective Tissue Growth Factor; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diterpenes; Epoxy Compounds; Irbesartan; Male; Phenanthrenes; Podocytes; Rats; Rats, Wistar; Tetrazoles; Transforming Growth Factor beta1 | 2012 |