triptolide has been researched along with Crohn Disease in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, M; Hou, HW; Wang, D; Wang, JM; Wu, R | 1 |
| Gong, J; Gu, L; Li, J; Li, N; Li, Y; Tian, Y; Yu, C; Zhang, W; Zhu, W | 1 |
| Gong, J; Guo, Z; Li, J; Li, N; Li, Y; Wu, R; Zhu, W | 1 |
| Gu, G; Hong, Z; Hu, D; Li, G; Li, J; Liu, S; Ren, H; Ren, J; Wang, G; Wu, X | 1 |
| Li, JS; Li, N; Li, Y; Qi, X; Xie, Y; Yu, C; Zhu, WM | 1 |
| Feng, A; Li, J; Li, N; Li, Y; Shan, T; Xie, Y; Yu, C; Zhu, W | 1 |
1 trial(s) available for triptolide and Crohn Disease
| Article | Year |
|---|---|
T2 enhances in situ level of Foxp3+ regulatory cells and modulates inflammatory cytokines in Crohn's disease.
Topics: Adult; Crohn Disease; Diterpenes; Epoxy Compounds; Female; Forkhead Transcription Factors; Humans; Interleukin-10; Intestinal Mucosa; Male; Middle Aged; Phenanthrenes; T-Lymphocytes, Regulatory; Tripterygium; Tumor Necrosis Factor-alpha | 2014 |
5 other study(ies) available for triptolide and Crohn Disease
| Article | Year |
|---|---|
Triptolide inhibits migration and proliferation of fibroblasts from ileocolonic anastomosis of patients with Crohn's disease via regulating the miR‑16‑1/HSP70 pathway.
Topics: Actins; Adult; Anastomosis, Surgical; Antagomirs; Anti-Inflammatory Agents; Apoptosis; Cell Movement; Cell Proliferation; China; Collagen Type I; Collagen Type III; Crohn Disease; Diterpenes; Down-Regulation; Epoxy Compounds; Female; Fibroblasts; HSP70 Heat-Shock Proteins; Humans; Male; MicroRNAs; Middle Aged; Phenanthrenes; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Up-Regulation | 2019 |
Triptolide induces suppressor of cytokine signaling-3 expression and promotes lamina propria mononuclear cells apoptosis in Crohn's colitis.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; bcl-X Protein; Cells, Cultured; Colon; Crohn Disease; Diterpenes; Epoxy Compounds; Female; Humans; Interleukin-10; Leukocytes, Mononuclear; Male; Mice; Mice, Inbred C3H; Mice, Transgenic; Mucous Membrane; Phenanthrenes; Proto-Oncogene Proteins c-bcl-2; RNA Polymerase II; STAT3 Transcription Factor; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins | 2013 |
Triptolide ameliorates ileocolonic anastomosis inflammation in IL-10 deficient mice by mechanism involving suppression of miR-155/SHIP-1 signaling pathway.
Topics: Anastomosis, Surgical; Animals; Blotting, Western; Colon; Crohn Disease; Cytokines; Diterpenes; Enzyme-Linked Immunosorbent Assay; Epoxy Compounds; Gene Expression; Ileum; Inositol Polyphosphate 5-Phosphatases; Interleukin-10; Leukocyte L1 Antigen Complex; Male; Mice; Mice, Inbred C3H; Mice, Knockout; MicroRNAs; Peroxidase; Phenanthrenes; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; Phosphoric Monoester Hydrolases; Plant Extracts; Postoperative Complications; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Tripterygium | 2013 |
Triptolide ameliorates IL-10-deficient mice colitis by mechanisms involving suppression of IL-6/STAT3 signaling pathway and down-regulation of IL-17.
Topics: Animals; CD4-Positive T-Lymphocytes; Colitis; Colon; Crohn Disease; Cytokine Receptor gp130; Diterpenes; Down-Regulation; Drug Evaluation, Preclinical; Epoxy Compounds; Female; Humans; Immunosuppressive Agents; Interleukin-10; Interleukin-17; Interleukin-6; Male; Mice; Mice, Inbred C3H; Organ Culture Techniques; Phenanthrenes; Phosphorylation; Phytotherapy; Plant Extracts; Protein Processing, Post-Translational; Signal Transduction; STAT3 Transcription Factor | 2010 |
Triptolide ameliorates Crohn's colitis is associated with inhibition of TLRs/NF-κB signaling pathway.
Topics: Animals; Crohn Disease; Diterpenes; Drug Evaluation, Preclinical; Epoxy Compounds; Humans; Interleukin-10; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myeloid Differentiation Factor 88; Phenanthrenes; Phytotherapy; Plant Extracts; Signal Transduction; Tissue Culture Techniques; Toll-Like Receptors; Transcription Factor RelA; Tripterygium | 2011 |