triptolide has been researched along with Colorectal Neoplasms in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (62.50) | 24.3611 |
| 2020's | 3 (37.50) | 2.80 |
| Authors | Studies |
|---|---|
| Chovancova, B; Kajsik, M; Krizanova, O; Liskova, V; Roller, L | 1 |
| Fan, J; He, H; Song, X; Wang, L; Zhang, Y | 1 |
| Du, F; Hu, Y; Huang, Y; Ji, H; Kaboli, PJ; Li, M; Wang, S; Wu, M; Wu, X; Wu, Z; Xiao, Z; Zhao, Y; Zou, T | 1 |
| Bai, R; Chen, Z; Gao, X; Li, Z; Liang, X; Liang, Z; Su, J; Wei, S; Xie, R; Ye, B | 1 |
| Hua, ZC; Lin, Y; Lu, M; Yang, X; Zhang, J; Zheng, W; Zhuang, H | 1 |
| Li, J; Li, M; Liu, M; Qi, X; Wang, X | 1 |
| Armesilla, AL; Cassidy, J; Darling, JL; Guo, X; Mathew, S; Wang, W; Xu, B | 1 |
| Li, C; Liu, J; Mei, Q; Shen, M; Wang, M; Wang, Y; Wang, Z; Xin, C; Yang, Z; Yue, Z | 1 |
8 other study(ies) available for triptolide and Colorectal Neoplasms
| Article | Year |
|---|---|
Camptothecin, triptolide, and apoptosis inducer kit have differential effects on mitochondria in colorectal carcinoma cells.
Topics: Apoptosis; Camptothecin; Colorectal Neoplasms; Diterpenes; Epoxy Compounds; Humans; Mitochondria; Phenanthrenes | 2022 |
Mechanisms of action of triptolide against colorectal cancer: insights from proteomic and phosphoproteomic analyses.
Topics: Colorectal Neoplasms; Diterpenes; Epoxy Compounds; Humans; Phenanthrenes; Phosphatidylinositol 3-Kinases; Proteome; Proteomics | 2022 |
The Anti-Tumor Mechanism and Target of Triptolide Based on Network Pharmacology and Molecular Docking.
Topics: Antineoplastic Agents, Alkylating; Carcinoma, Non-Small-Cell Lung; Chemokine CCL2; Collagen Type I, alpha 1 Chain; Colorectal Neoplasms; Cyclooxygenase 2; Diterpenes; Epoxy Compounds; Heme Oxygenase-1; Humans; Interleukin-17; Interleukin-6; Interleukin-8; Lung Neoplasms; Matrix Metalloproteinase 2; Mitogen-Activated Protein Kinase 8; Molecular Docking Simulation; Molecular Targeted Therapy; Network Pharmacology; NF-kappa B; Pancreatic Neoplasms; Phenanthrenes; Proto-Oncogene Proteins c-jun; Receptor, ErbB-2; STAT1 Transcription Factor; Structure-Activity Relationship; Toll-Like Receptors; Vascular Endothelial Growth Factor A | 2021 |
Inhibition of RNA polymerase III transcription by Triptolide attenuates colorectal tumorigenesis.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Diterpenes; Epoxy Compounds; Female; Gene Expression Regulation, Neoplastic; HCT116 Cells; Humans; Mice; Phenanthrenes; Promoter Regions, Genetic; RNA, Ribosomal, 5S; RNA, Transfer; Transcription Factor TFIIIB; Transcription, Genetic; Tumor Burden; Xenograft Model Antitumor Assays | 2019 |
Herbal compound triptolide synergistically enhanced antitumor activity of vasostatin120-180.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Calreticulin; Cell Line; Cell Line, Tumor; Colorectal Neoplasms; Diterpenes; Drug Synergism; Drugs, Chinese Herbal; Epoxy Compounds; Ethnopharmacology; HCT116 Cells; Humans; Mice; Mice, Nude; Neoplasms; Neovascularization, Pathologic; Peptide Fragments; Phenanthrenes; Random Allocation; Recombinant Proteins; Tripterygium; Xenograft Model Antitumor Assays | 2013 |
NF-κB signaling inhibition and anticancer activities of LLDT-246 on human colorectal cancer HCT-116 cells in vitro.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Nucleus; Cell Survival; Colorectal Neoplasms; Diterpenes; Down-Regulation; Drug Synergism; Epoxy Compounds; Gene Expression Regulation, Neoplastic; HCT116 Cells; Humans; I-kappa B Proteins; Inhibitory Concentration 50; Mice; Mitochondria; Neoplasm Proteins; NF-kappa B; NF-KappaB Inhibitor alpha; Phenanthrenes; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; STAT3 Transcription Factor; Transcription Factor RelA; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53; Up-Regulation | 2014 |
Triptolide simultaneously induces reactive oxygen species, inhibits NF-kappaB activity and sensitizes 5-fluorouracil in colorectal cancer cell lines.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites, Antineoplastic; Cell Line, Tumor; Cell Survival; Colorectal Neoplasms; Diterpenes; DNA Probes; Drug Agonism; Drug Therapy, Combination; Epoxy Compounds; Fluorouracil; Genes, Reporter; Humans; Luciferases; NF-kappa B; Phenanthrenes; Reactive Oxygen Species | 2010 |
Triptolide inhibits colon-rectal cancer cells proliferation by induction of G1 phase arrest through upregulation of p21.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Cyclin A1; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Cyclin-Dependent Kinase Inhibitor p21; Diterpenes; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Epoxy Compounds; G1 Phase Cell Cycle Checkpoints; GA-Binding Protein Transcription Factor; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Lymphoid Enhancer-Binding Factor 1; Mitogen-Activated Protein Kinase 1; Phenanthrenes; Phosphorylation; Proto-Oncogene Proteins c-akt; T Cell Transcription Factor 1; Up-Regulation | 2012 |