triptolide has been researched along with Colonic Neoplasms in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (33.33) | 29.6817 |
| 2010's | 6 (40.00) | 24.3611 |
| 2020's | 4 (26.67) | 2.80 |
| Authors | Studies |
|---|---|
| Blazar, BR; Cuellar, RA; Georg, GI; Gurvich, VJ; Lis, LG; Morgan, ML; Norris, BJ; Patil, S; Schumacher, RJ; Suryanarayanan, R | 1 |
| Cai, XJ; Cao, JW; Fei, WD; Ni, JJ; Wang, Z; Xu, H; Xu, YY; Yang, GY | 1 |
| Huang, X; Jiang, Z; Li, H; Li, L; Mei, H; Pan, G; Sun, L; Wang, T; Wang, X; Zhang, L | 1 |
| Cao, G; Gao, C; Gao, G; Jiang, X; Wang, W; Zhao, J | 1 |
| Cai, SL; Li, B; Li, XQ; Qi, ZP; Yalikong, A; Zhong, YS; Zhou, PH | 1 |
| Li, J; Qi, Y | 1 |
| Hua, ZC; Li, J; Lin, Y; Peng, N; Zhuang, H | 1 |
| Li, G; Liu, Y; Xiao, E; Yuan, L | 1 |
| Banerjee, S; Beyer, G; Chugh, R; Dawra, R; Dudeja, V; Li, L; Majumder, K; Oliveira, A; Saluja, A; Sangwan, V; Skube, SJ; Subramanian, S | 1 |
| Fan, D; Jin, H; Mei, Q; Wang, Z; Xu, R | 1 |
| He, M; Jiang, Y; Li, H; Liu, Y; Peng, K; Song, F; Sun, X; Wu, WK; Yang, Y; Zhao, L | 1 |
| Chung, C; Fidler, JM; Gao, M; Li, K; Rosen, GD; Ross, JA; Wei, K | 1 |
| Chiu, P; Ho, WK; Ko, JK; Leung, WC | 1 |
| Jin, J; Lou, Y; Tong, X; Yao, H; Zheng, S; Zhu, L | 1 |
| Lin, XL; Tang, XY; Tao, WH; Wei, B; Zhu, YQ | 1 |
15 other study(ies) available for triptolide and Colonic Neoplasms
| Article | Year |
|---|---|
Phosphonooxymethyl Prodrug of Triptolide: Synthesis, Physicochemical Characterization, and Efficacy in Human Colon Adenocarcinoma and Ovarian Cancer Xenografts.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Line, Tumor; Colon; Colonic Neoplasms; Diterpenes; Drug Stability; Epoxy Compounds; Female; HT29 Cells; Humans; Mice; Mice, Nude; Organophosphates; Ovarian Neoplasms; Ovary; Phenanthrenes; Prodrugs; Solubility | 2015 |
Combination of metronomic administration and target delivery strategies to improve the anti-angiogenic and anti-tumor effects of triptolide.
Topics: Administration, Metronomic; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Proliferation; Cell Survival; Colonic Neoplasms; Diterpenes; Drug Compounding; Epoxy Compounds; HCT116 Cells; Human Umbilical Vein Endothelial Cells; Humans; Liposomes; Mice; Oligopeptides; Phenanthrenes; Tissue Distribution; Treatment Outcome; Xenograft Model Antitumor Assays | 2020 |
Antitumor properties of triptolide: phenotype regulation of macrophage differentiation.
Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Breast Neoplasms; Cell Differentiation; Cell Proliferation; Colonic Neoplasms; Diterpenes; Epoxy Compounds; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Mice, Nude; Phenanthrenes; Phenotype; Tumor Cells, Cultured; Tumor Microenvironment; Tumor-Associated Macrophages; Xenograft Model Antitumor Assays | 2020 |
Triptolide decreases tumor-associated macrophages infiltration and M2 polarization to remodel colon cancer immune microenvironment via inhibiting tumor-derived CXCL12.
Topics: Animals; Apoptosis; Cell Line; Cell Line, Tumor; Cell Proliferation; Chemokine CXCL12; Colonic Neoplasms; Diterpenes; Down-Regulation; Epoxy Compounds; HT29 Cells; Humans; Male; Mice; Mice, Inbred BALB C; NF-kappa B; Phenanthrenes; RAW 264.7 Cells; Tumor Microenvironment; Tumor-Associated Macrophages | 2021 |
A Triptolide Loaded HER2-Targeted Nano-Drug Delivery System Significantly Suppressed the Proliferation of HER2-Positive and BRAF Mutant Colon Cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinogenesis; Cell Cycle; Cell Death; Cell Proliferation; Cell Survival; Colonic Neoplasms; Diterpenes; Drug Delivery Systems; Epoxy Compounds; Female; HT29 Cells; Humans; Inhibitory Concentration 50; Kidney; Liver; Mice; Mice, Inbred BALB C; Mice, Nude; Mutation; Nanomedicine; Nanoparticles; Phenanthrenes; Proto-Oncogene Proteins B-raf; Receptor, ErbB-2; Signal Transduction | 2021 |
RETRACTED: Triptolide inhibits the growth and migration of colon carcinoma cells by down-regulation of miR-191.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Alkylating; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colonic Neoplasms; Diterpenes; Down-Regulation; Epoxy Compounds; Gene Expression Regulation, Neoplastic; Humans; Mice; MicroRNAs; Phenanthrenes; Xenograft Model Antitumor Assays | 2019 |
Herbal compound triptolide synergistically enhanced antitumor activity of amino-terminal fragment of urokinase.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colonic Neoplasms; Diterpenes; Drug Synergism; Epoxy Compounds; HCT116 Cells; Human Umbilical Vein Endothelial Cells; Humans; Male; Mice; Peptides; Phenanthrenes; Signal Transduction; Tumor Burden; Urokinase-Type Plasminogen Activator; Xenograft Model Antitumor Assays | 2013 |
Triptolide synergistically enhances antitumor activity of oxaliplatin in colon carcinoma in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; beta Catenin; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Disease Models, Animal; Diterpenes; Drug Synergism; Epoxy Compounds; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Molecular Structure; Organoplatinum Compounds; Oxaliplatin; Phenanthrenes; Protein Transport | 2014 |
Triptolide abrogates growth of colon cancer and induces cell cycle arrest by inhibiting transcriptional activation of E2F.
Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Cell Cycle Checkpoints; Cell Survival; Colonic Neoplasms; Diterpenes; E2F Transcription Factors; Epoxy Compounds; Female; HCT116 Cells; HT29 Cells; Humans; Mice, Nude; Organophosphates; Phenanthrenes; Xenograft Model Antitumor Assays | 2015 |
Triptolide downregulates Rac1 and the JAK/STAT3 pathway and inhibits colitis-related colon cancer progression.
Topics: Animals; Cell Transformation, Neoplastic; Colitis; Colonic Neoplasms; Dextran Sulfate; Dimethylhydrazines; Diterpenes; Epoxy Compounds; Humans; Interleukin-6; Janus Kinases; Male; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Mice, Nude; Neoplasm Transplantation; Phenanthrenes; rac1 GTP-Binding Protein; Signal Transduction; STAT3 Transcription Factor; Tumor Burden | 2009 |
Triptolide inhibits colon cancer cell proliferation and induces cleavage and translocation of 14-3-3 epsilon.
Topics: 14-3-3 Proteins; Amino Acid Sequence; Animals; Antineoplastic Agents, Alkylating; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Diterpenes; Electrophoresis, Gel, Two-Dimensional; Epoxy Compounds; Humans; Medicine, Chinese Traditional; Mice; Mice, Nude; Molecular Sequence Data; Phenanthrenes; Proteomics; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Transplantation, Heterologous; Tripterygium | 2012 |
PG490-88, a derivative of triptolide, causes tumor regression and sensitizes tumors to chemotherapy.
Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Cycle; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Diterpenes; Drug Resistance, Neoplasm; Drug Synergism; Enzyme Inhibitors; Epoxy Compounds; Humans; Irinotecan; Lung Neoplasms; Mice; Mice, Nude; Phenanthrenes; Transplantation, Heterologous; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2003 |
Herbal diterpenoids induce growth arrest and apoptosis in colon cancer cells with increased expression of the nonsteroidal anti-inflammatory drug-activated gene.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Colonic Neoplasms; Cyclooxygenase 2; Cytokines; Diterpenes; DNA Fragmentation; Epoxy Compounds; Flow Cytometry; Fluorescent Dyes; Gene Expression Regulation, Neoplastic; Growth Differentiation Factor 15; HT29 Cells; Humans; Immunoblotting; Indoles; Phenanthrenes; Poly(ADP-ribose) Polymerase Inhibitors; PPAR gamma; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles | 2007 |
Triptolide inhibits cyclooxygenase-2 and inducible nitric oxide synthase expression in human colon cancer and leukemia cells.
Topics: Base Sequence; Cell Line, Tumor; Cell Survival; China; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diterpenes; DNA Primers; Epoxy Compounds; Humans; K562 Cells; Leukemia; Medicine, Chinese Traditional; Nitric Oxide Synthase Type II; Phenanthrenes; RNA, Messenger; Transcription, Genetic | 2007 |
Synergistic effect of triptolide combined with 5-fluorouracil on colon carcinoma.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites, Antineoplastic; Apoptosis; Carcinoma; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Diterpenes; Drug Synergism; Epoxy Compounds; Fluorouracil; HT29 Cells; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Phenanthrenes; Plant Extracts; Tripterygium; Xenograft Model Antitumor Assays | 2007 |