triptolide has been researched along with Cancer of Prostate in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 13 (92.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, Y; Feng, H; Li, Y; Tang, H; Xu, H | 1 |
| Cao, QQ; Dong, YF; Gu, X; Li, W; Liao, K; Liu, BD; Liu, Y; Wan, ZJ; Zhu, Q | 1 |
| Chen, JC; Jiang, MJ; Lu, P; Shen, G; Song, RJ; Xu, C; Zhang, W; Zhou, YQ | 1 |
| Guo, Q; Hu, SB; Liang, BL; Luo, Y; Nan, XX; Wei, YB; Xu, YF; Yang, JR; Yi, L; Zhang, H; Zhu, N | 1 |
| Chai, CS; Hao, L; Huang, WW; Lei, M; Tamgue, O; Wei, YM; Zambe, JC; Zhang, B | 1 |
| Feng, H; Li, Y; Tang, H; Xu, H | 1 |
| Han, Y; Huang, W; Lei, M; Mao, L; Yan, J; Zhang, Z; Zhao, F | 1 |
| Feng, QQ; Gu, X; Li, W; Liu, BD; Lu, D | 1 |
| Chen, X; Fan, B; Wang, L; Wang, S; Yang, D; Yuan, Q; Yuan, S; Zhang, H | 1 |
| Huo, H; Li, W; Li, XX; Liu, Y; Wang, LM; Wang, Q; Wu, JJ; Yang, L; Yu, Y | 1 |
| Cui, QC; Dou, QP; Kanwar, J; Lu, L; Schmitt, S; Zhang, C; Zhao, C | 1 |
| Chai, C; Gao, K; He, T; Huang, ME; Huang, W; Lei, L; Lei, M; Li, H; Liu, Z; Qiao, X; Shi, C; Wang, J; Yang, Y; Yao, L; Zhang, B; Zheng, Y; Zhong, S; Zhou, P | 1 |
| Xiaowen, H; Yi, S | 1 |
| Guo, J; Ma, YC; Wang, WJ; Yang, D; Zhang, PY; Zhang, R; Zheng, MH | 1 |
14 other study(ies) available for triptolide and Cancer of Prostate
| Article | Year |
|---|---|
Semisynthesis of triptolide analogues: effect of B-ring substituents on cytotoxic activities.
Topics: Antineoplastic Agents; Cell Proliferation; Diterpenes; Drug Screening Assays, Antitumor; Epoxy Compounds; Glioma; Humans; Male; Models, Molecular; Molecular Structure; Organic Chemicals; Phenanthrenes; Prostatic Neoplasms; Structure-Activity Relationship; Tumor Cells, Cultured | 2014 |
Alteration of Androgen Receptor Protein Stability by Triptolide in LNCaP Cells.
Topics: Antineoplastic Agents, Alkylating; Blotting, Western; Calpain; Cell Line, Tumor; Cell Proliferation; Cycloheximide; Diterpenes; Epoxy Compounds; Humans; Male; Phenanthrenes; Prostatic Neoplasms; Protein Stability; Receptors, Androgen | 2018 |
pH-triggered charge-reversal and redox-sensitive drug-release polymer micelles codeliver doxorubicin and triptolide for prostate tumor therapy.
Topics: Adsorption; Animals; Cell Line, Tumor; Diterpenes; Doxorubicin; Drug Carriers; Drug Delivery Systems; Drug Liberation; Drug Synergism; Epoxy Compounds; Humans; Hydrogen-Ion Concentration; Male; Maleic Anhydrides; Mice, Inbred BALB C; Mice, Nude; Micelles; Nanoparticles; Oxidation-Reduction; Particle Size; Phenanthrenes; Polymers; Prostatic Neoplasms; Proton Magnetic Resonance Spectroscopy; Static Electricity | 2018 |
Triptolide inhibits the multidrug resistance in prostate cancer cells via the downregulation of MDR1 expression.
Topics: Antineoplastic Agents, Alkylating; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Cell Cycle; Cell Proliferation; Diterpenes; Down-Regulation; Drug Resistance, Multiple; Epoxy Compounds; Humans; Male; Phenanthrenes; Prostatic Neoplasms; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured | 2013 |
Triptolide inhibits histone methyltransferase EZH2 and modulates the expression of its target genes in prostate cancer cells.
Topics: Cell Line, Tumor; Cell Proliferation; Diterpenes; Down-Regulation; Enhancer of Zeste Homolog 2 Protein; Epoxy Compounds; Gene Expression Regulation, Neoplastic; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Humans; Male; Phenanthrenes; Polycomb Repressive Complex 2; Prostatic Neoplasms; RNA, Messenger | 2013 |
Design, synthesis and structure-activity relationships studies on the D ring of the natural product triptolide.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Diterpenes; Drug Design; Epoxy Compounds; Female; Humans; Male; Models, Molecular; Ovarian Neoplasms; Ovary; Phenanthrenes; Prostate; Prostatic Neoplasms; Structure-Activity Relationship; Tripterygium | 2014 |
Triptolide induces protective autophagy through activation of the CaMKKβ-AMPK signaling pathway in prostate cancer cells.
Topics: AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Autophagy; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinase Kinase; Cell Proliferation; Diterpenes; Endoplasmic Reticulum Stress; Epoxy Compounds; Humans; Immunoenzyme Techniques; Male; Mice; Mice, Nude; Phenanthrenes; Prostatic Neoplasms; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; TOR Serine-Threonine Kinases; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2016 |
[Effects of triptolide on the expression of androgen receptor in human prostate LNCaP cells and its mechanism of action].
Topics: Cell Line, Tumor; Diterpenes; Down-Regulation; Epoxy Compounds; Genetic Vectors; Humans; Male; NF-kappa B; Phenanthrenes; Phosphatidylinositol 3-Kinases; Promoter Regions, Genetic; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; RNA, Messenger; Signal Transduction; Transcriptional Activation | 2015 |
Triptolide inhibits the migration and invasion of human prostate cancer cells via Caveolin-1/CD147/MMPs pathway.
Topics: Antineoplastic Agents, Phytogenic; Basigin; Caveolin 1; Cell Line, Tumor; Cell Movement; Cell Proliferation; Diterpenes; Dose-Response Relationship, Drug; Down-Regulation; Epoxy Compounds; Gene Expression Regulation, Neoplastic; Humans; Male; Matrix Metalloproteinases; Neoplasm Invasiveness; Phenanthrenes; Prostatic Neoplasms; RNA Interference; Signal Transduction; Time Factors; Transfection | 2016 |
MAPKs are not involved in triptolide-induced cell growth inhibition and apoptosis in prostate cancer cell lines with different p53 status.
Topics: Antineoplastic Agents, Alkylating; Apoptosis; Cell Line, Tumor; Cytostatic Agents; Diterpenes; Epoxy Compounds; Humans; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Phenanthrenes; Prostatic Neoplasms; Protein Kinase Inhibitors; Tumor Suppressor Protein p53 | 2011 |
Inhibition of tumor cellular proteasome activity by triptolide extracted from the Chinese medicinal plant 'thunder god vine'.
Topics: Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Breast Neoplasms; Caspase 3; Cyclin-Dependent Kinase Inhibitor p27; Diterpenes; Epoxy Compounds; Female; Humans; I-kappa B Proteins; Male; NF-KappaB Inhibitor alpha; Phenanthrenes; Plants, Medicinal; Poly(ADP-ribose) Polymerases; Prostatic Neoplasms; Proteasome Inhibitors; Tumor Cells, Cultured; Ubiquitin | 2011 |
Triptolide inhibits the proliferation of prostate cancer cells and down-regulates SUMO-specific protease 1 expression.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cysteine Endopeptidases; Disease Progression; Diterpenes; Down-Regulation; Endopeptidases; Epoxy Compounds; Gene Expression Regulation, Neoplastic; Humans; JNK Mitogen-Activated Protein Kinases; Male; Mice; Phenanthrenes; Prostatic Neoplasms; Receptors, Androgen; RNA, Messenger; Transcription, Genetic; Xenograft Model Antitumor Assays | 2012 |
Triptolide sensitizes TRAIL-induced apoptosis in prostate cancer cells via p53-mediated DR5 up-regulation.
Topics: Antineoplastic Agents, Alkylating; Apoptosis; Cell Line, Tumor; Cell Survival; Diterpenes; Epoxy Compounds; Gene Expression Regulation, Neoplastic; Humans; Male; Phenanthrenes; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-mdm2; Receptors, TNF-Related Apoptosis-Inducing Ligand; Signal Transduction; TNF-Related Apoptosis-Inducing Ligand; Tumor Suppressor Protein p53 | 2012 |
[Effects of triptolide on prostate carcinoma in mouse RM-1 cells].
Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Caspase 3; Cell Line, Tumor; Cell Proliferation; Diterpenes; Epoxy Compounds; Male; Mice; Phenanthrenes; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2007 |