Page last updated: 2024-09-02

triptolide and Breast Neoplasms

triptolide has been researched along with Breast Neoplasms in 24 studies

Research

Studies (24)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (4.17)	18.2507
2000's	4 (16.67)	29.6817
2010's	13 (54.17)	24.3611
2020's	6 (25.00)	2.80

Authors

Authors	Studies
Chen, M; Dong, C; Fan, T; Fang, K; Hu, X; Li, R; Shi, S; Sun, Y; Tong, X; Wu, J; Yang, J; Yang, X	1
Du, J; Fei, F; Li, C; Li, Y; Liu, K; Wang, X; Zhang, S; Zheng, M	1
Huang, X; Jiang, Z; Li, H; Li, L; Mei, H; Pan, G; Sun, L; Wang, T; Wang, X; Zhang, L	1
Aguayo-Ortiz, R; Dominguez, L; Melchy-Pérez, E; Rosenstein, Y; Uriostegui-Arcos, M; Valencia-Morales, MDP; Zurita, M	1
Xu, F; Zhu, Y	1
Cao, Z; Fu, C; Gu, H; Li, J; Luo, X; Ma, J; Ren, Y; Shi, J; Wu, Y; Zhang, J	1
Fu, CM; Li, JX; Shi, JF; Wu, YH; Xu, HT; Zhang, JM	1
Deng, Y; He, P; Li, F; Li, Q; Liu, J; Mei, X; Shu, Z; Tong, Y; Yang, J; Yang, Y; Zhang, Y; Zhao, Q	1
Chen, M; Jiang, W; Liang, Z; Liao, X; Mao, A; Qin, Q; Tan, Q; Wei, C; Xiao, C; Yang, W	1
Hu, H; Li, F; Liu, Q; Wang, W; Xu, C; Yu, D	1
Chiu, GN; Tan, BJ	1
Huang, Y; Li, J; Li, X; Liu, R; Shen, X; Yang, Y	1
Andreeff, M; Battula, VL; Chang, JT; Mani, SA; Miura, N; Porter, W; Ramirez-Peña, EQ; Sarkar, TR; Sphyris, N; Taube, JH; Vijay, GV; Werden, SJ	1
Jiang, ZZ; Li, H; Pan, GF; Sun, LX; Yang, J; Zhang, LY	1
Cheng, X; Liang, P; Lu, L; Shi, W; Wang, G; Zhang, D; Zhao, C	1
Li, J; Qu, Z; Su, T; Wang, Y; Xiong, J; Yang, Q; Zhou, S	1
Fu, J; Liang, M	1
Jang, YH; Kang, DW; Kim, MK; Lee, JY; Min, do S; Oh, DH; Park, MH; Park, SY; Woo, TM	1
Marignani, PA; Robertson, GS; Sayat, R; Soundararajan, R	1
Cui, QC; Dou, QP; Kanwar, J; Lu, L; Schmitt, S; Zhang, C; Zhao, C	1
Halaby, R; Messina, ME	1
Chiu, GN; Tan, BH; Tan, BJ	1
Chen, J; Guo, Z; Pei, XF; Underhill, CB; Wang, L; Xu, XM; Yang, J; Yang, S; Zhang, L	1
Adachi, I; Wei, YS	1

Reviews

1 review(s) available for triptolide and Breast Neoplasms

Article	Year
[Mechanisms and application of triptolide against breast cancer]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2021, Volume: 46, Issue:13 Topics: Breast Neoplasms; Diterpenes; Epoxy Compounds; Female; Humans; Phenanthrenes; Tumor Microenvironment	2021

Other Studies

23 other study(ies) available for triptolide and Breast Neoplasms

Article	Year
A Dual Stimuli-Responsive Nanoplatform Loaded Pt Advanced healthcare materials, 2023, Volume: 12, Issue:28 Topics: Breast Neoplasms; Cell Line, Tumor; Cisplatin; Diterpenes; Female; Humans; Prodrugs; Tumor Microenvironment	2023
EMT-related protein expression in polyploid giant cancer cells and their daughter cells with different passages after triptolide treatment. Medical oncology (Northwood, London, England), 2019, Aug-12, Volume: 36, Issue:9 Topics: Antineoplastic Agents, Alkylating; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Diterpenes; Epithelial-Mesenchymal Transition; Epoxy Compounds; Female; Gene Expression Regulation, Neoplastic; Giant Cells; Humans; Neoplasm Invasiveness; Ovarian Neoplasms; Phenanthrenes; Polyploidy	2019
Antitumor properties of triptolide: phenotype regulation of macrophage differentiation. Cancer biology & therapy, 2020, Volume: 21, Issue:2 Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Breast Neoplasms; Cell Differentiation; Cell Proliferation; Colonic Neoplasms; Diterpenes; Epoxy Compounds; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Mice, Nude; Phenanthrenes; Phenotype; Tumor Cells, Cultured; Tumor Microenvironment; Tumor-Associated Macrophages; Xenograft Model Antitumor Assays	2020
Disruption of TFIIH activities generates a stress gene expression response and reveals possible new targets against cancer. Open biology, 2020, Volume: 10, Issue:6 Topics: Breast Neoplasms; Cell Line, Tumor; Cell Transformation, Neoplastic; Diterpenes; DNA Helicases; DNA-Binding Proteins; Epoxy Compounds; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Models, Biological; Molecular Dynamics Simulation; Phenanthrenes; Phenylenediamines; Pyrimidines; Sequence Analysis, RNA; Transcription Factor TFIIH	2020
The effects of TPL-PEI-CyD on suppressing performance of MCF-7 stem cells. Pakistan journal of pharmaceutical sciences, 2020, Volume: 33, Issue:2(Suppleme Topics: Apoptosis; Breast Neoplasms; CD24 Antigen; Cell Line, Tumor; Cyclodextrins; Diterpenes; Epoxy Compounds; Female; Humans; Hyaluronan Receptors; Imines; MCF-7 Cells; Medicine, Chinese Traditional; Phenanthrenes; Polyethylenes; Stem Cells; Transforming Growth Factor beta1	2020
Novel CD44-targeting and pH/redox-dual-stimuli-responsive core-shell nanoparticles loading triptolide combats breast cancer growth and lung metastasis. Journal of nanobiotechnology, 2021, Jun-23, Volume: 19, Issue:1 Topics: Animals; Apoptosis; Breast Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Cell Proliferation; Diterpenes; Drug Liberation; Epoxy Compounds; Female; Humans; Hyaluronan Receptors; Hyaluronic Acid; Hydrogen-Ion Concentration; Lung Neoplasms; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Oxidation-Reduction; Phenanthrenes; Wound Healing	2021
Triptolide sensitizes breast cancer cells to Doxorubicin through the DNA damage response inhibition. Molecular carcinogenesis, 2018, Volume: 57, Issue:6 Topics: Antineoplastic Agents; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Breast Neoplasms; Cell Line, Tumor; Diterpenes; DNA Breaks, Double-Stranded; DNA Damage; Doxorubicin; Epoxy Compounds; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Phenanthrenes	2018
Triptolide Suppresses Growth of Breast Cancer by Targeting HMGB1 in Vitro and in Vivo. Biological & pharmaceutical bulletin, 2019, Jun-01, Volume: 42, Issue:6 Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Diterpenes; Epoxy Compounds; Female; HMGB1 Protein; Humans; MCF-7 Cells; Mice; Mice, Inbred BALB C; Molecular Targeted Therapy; NF-kappa B; Phenanthrenes; Recombinant Proteins; RNA, Messenger; Signal Transduction; Toll-Like Receptor 4; Tumor Stem Cell Assay; Xenograft Model Antitumor Assays	2019
Triptolide Inhibits Breast Cancer Cell Metastasis Through Inducing the Expression of miR-146a, a Negative Regulator of Rho GTPase. Oncology research, 2019, Sep-23, Volume: 27, Issue:9 Topics: Breast Neoplasms; Cell Line, Tumor; Diterpenes; Epoxy Compounds; Female; Humans; MicroRNAs; Neoplasm Metastasis; Phenanthrenes; rho GTP-Binding Proteins; Tripterygium	2019
Role of oxidative stress, endoplasmic reticulum stress and ERK activation in triptolide-induced apoptosis. International journal of oncology, 2013, Volume: 42, Issue:5 Topics: Apoptosis; Breast Neoplasms; Butadienes; Cell Line, Tumor; Cell Proliferation; Cell Survival; Clinical Trials as Topic; Diterpenes; eIF-2 Kinase; Endoplasmic Reticulum Stress; Epoxy Compounds; Eukaryotic Initiation Factor-2; Extracellular Signal-Regulated MAP Kinases; Female; Gene Expression Regulation, Neoplastic; Humans; MAP Kinase Kinase Kinases; Nitriles; Oxidative Stress; Phenanthrenes; Reactive Oxygen Species; Signal Transduction	2013
Triptolide-induced in vitro and in vivo cytotoxicity in human breast cancer stem cells and primary breast cancer cells. Oncology reports, 2014, Volume: 31, Issue:5 Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Breast Neoplasms; Carcinoma, Ductal, Breast; Diterpenes; Drugs, Chinese Herbal; Epoxy Compounds; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplastic Stem Cells; Phenanthrenes; Spheroids, Cellular; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2014
GD3 synthase regulates epithelial-mesenchymal transition and metastasis in breast cancer. Oncogene, 2015, Jun-04, Volume: 34, Issue:23 Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Diterpenes; Epithelial-Mesenchymal Transition; Epoxy Compounds; Female; Forkhead Transcription Factors; Humans; Mice; Neoplasm Metastasis; Neoplasms, Experimental; Phenanthrenes; Prognosis; Promoter Regions, Genetic; Proto-Oncogene Proteins c-met; RNA, Small Interfering; Sialyltransferases; Signal Transduction	2015
Triptolide inhibits human breast cancer MCF-7 cell growth via downregulation of the ERα-mediated signaling pathway. Acta pharmacologica Sinica, 2015, Volume: 36, Issue:5 Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Proliferation; Diterpenes; Dose-Response Relationship, Drug; Down-Regulation; Epoxy Compounds; Estrogen Antagonists; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Mice, Inbred BALB C; Mice, Nude; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phenanthrenes; Phosphorylation; Protein Kinase Inhibitors; RNA Interference; RNA, Messenger; Signal Transduction; Time Factors; Transfection; Tumor Burden; Xenograft Model Antitumor Assays	2015
Triptolide sensitizes human breast cancer cells to tumor necrosis factor‑α‑induced apoptosis by inhibiting activation of the nuclear factor‑κB pathway. Molecular medicine reports, 2016, Volume: 13, Issue:4 Topics: Apoptosis; Baculoviral IAP Repeat-Containing 3 Protein; Breast Neoplasms; Caspase 3; Caspase 9; Cell Line, Tumor; Cell Proliferation; Diterpenes; Epoxy Compounds; Female; Humans; I-kappa B Proteins; Inhibitor of Apoptosis Proteins; MCF-7 Cells; NF-kappa B; Phenanthrenes; Poly(ADP-ribose) Polymerases; RNA, Messenger; Signal Transduction; Tumor Necrosis Factor-alpha; Ubiquitin-Protein Ligases; X-Linked Inhibitor of Apoptosis Protein	2016
Triptolide has anticancer and chemosensitization effects by down-regulating Akt activation through the MDM2/REST pathway in human breast cancer. Oncotarget, 2016, Apr-26, Volume: 7, Issue:17 Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Biomarkers, Tumor; Breast Neoplasms; Cell Cycle; Cell Proliferation; Diterpenes; Down-Regulation; Drug Resistance, Neoplasm; Epoxy Compounds; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Phenanthrenes; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-mdm2; Repressor Proteins; Signal Transduction; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2016
Triptolide inhibits interferon-gamma-induced programmed death-1-ligand 1 surface expression in breast cancer cells. Cancer letters, 2008, Nov-08, Volume: 270, Issue:2 Topics: Antigens, CD; Antineoplastic Agents, Phytogenic; B7-H1 Antigen; Breast Neoplasms; Cell Line, Tumor; Cell Membrane; Diterpenes; Dose-Response Relationship, Drug; Down-Regulation; Epoxy Compounds; Female; Humans; Interferon-gamma; Phenanthrenes; Recombinant Proteins; Tumor Escape	2008
Triptolide-induced suppression of phospholipase D expression inhibits proliferation of MDA-MB-231 breast cancer cells. Experimental & molecular medicine, 2009, Sep-30, Volume: 41, Issue:9 Topics: Antineoplastic Agents, Alkylating; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Diterpenes; Epoxy Compounds; Female; Gene Expression Regulation, Neoplastic; Humans; NF-kappa B; Phenanthrenes; Phospholipase D	2009
Triptolide: An inhibitor of a disintegrin and metalloproteinase 10 (ADAM10) in cancer cells. Cancer biology & therapy, 2009, Volume: 8, Issue:21 Topics: ADAM Proteins; ADAM10 Protein; Amyloid Precursor Protein Secretases; Antineoplastic Agents, Alkylating; Apoptosis; Breast Neoplasms; Cell Growth Processes; Cell Line, Tumor; Chromatography, Affinity; Diterpenes; Epoxy Compounds; Humans; Lymphoma, Large B-Cell, Diffuse; Membrane Proteins; Phenanthrenes; Protease Inhibitors; U937 Cells	2009
Inhibition of tumor cellular proteasome activity by triptolide extracted from the Chinese medicinal plant 'thunder god vine'. Anticancer research, 2011, Volume: 31, Issue:1 Topics: Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Breast Neoplasms; Caspase 3; Cyclin-Dependent Kinase Inhibitor p27; Diterpenes; Epoxy Compounds; Female; Humans; I-kappa B Proteins; Male; NF-KappaB Inhibitor alpha; Phenanthrenes; Plants, Medicinal; Poly(ADP-ribose) Polymerases; Prostatic Neoplasms; Proteasome Inhibitors; Tumor Cells, Cultured; Ubiquitin	2011
Does triptolide induce lysosomal-mediated apoptosis in human breast cancer cells? Medical hypotheses, 2011, Volume: 77, Issue:1 Topics: Antineoplastic Agents, Alkylating; Apoptosis; Breast Neoplasms; Diterpenes; Epoxy Compounds; Female; Humans; Lysosomes; Phenanthrenes	2011
Effect of triptolide on focal adhesion kinase and survival in MCF-7 breast cancer cells. Oncology reports, 2011, Volume: 26, Issue:5 Topics: Antineoplastic Agents, Alkylating; Breast Neoplasms; Cell Adhesion; Cell Growth Processes; Cell Line, Tumor; Cell Survival; Diterpenes; Epoxy Compounds; Female; Focal Adhesion Protein-Tyrosine Kinases; Humans; Phenanthrenes	2011
Triptolide inhibits the growth and metastasis of solid tumors. Molecular cancer therapeutics, 2003, Volume: 2, Issue:1 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Breast Neoplasms; Cell Division; Diterpenes; Epoxy Compounds; Female; Humans; Melanoma; Melanoma, Experimental; Mice; Neoplasm Metastasis; Phenanthrenes; Stomach Neoplasms; Tumor Cells, Cultured; Urinary Bladder Neoplasms	2003
Inhibitory effect of triptolide on colony formation of breast and stomach cancer cell lines. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1991, Volume: 12, Issue:5 Topics: Antineoplastic Agents; Breast Neoplasms; Diterpenes; Epoxy Compounds; Humans; Leukemia, Promyelocytic, Acute; Phenanthrenes; Stomach Neoplasms; Tumor Cells, Cultured; Tumor Stem Cell Assay	1991