triptolide has been researched along with Asthma in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 7 (50.00) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 2 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, H; Han, L; Miao, Y; Wei, L; Zhang, Z | 1 |
| Chen, M; He, S; Huang, L; Liang, R; Lin, X; Lv, Z | 1 |
| Chen, M; Huang, L; Jiang, S; Liang, R; Lin, X; Lv, Z; Shi, J; Zhang, W | 2 |
| Fang, CS; Liu, XS; Mo, BW; Wang, CM; Xiong, WN; Xu, YJ; Zhang, ZX | 1 |
| Guo, AY; Guo, XM; Yan, SZ | 1 |
| Chen, M; Jiang, S; Lv, Z | 1 |
| Chen, MX; Huang, JW; Lin, Y; Mo, BW; Wang, CM; Wei, JH; Xu, Q; Zeng, JR; Zhou, Y | 1 |
| He, J; Liang, B; Song, Z; Zhang, Y | 1 |
| Lin, KX; Qian, GS; Wang, CZ | 1 |
| Wang, XH; Zhang, ZY | 1 |
| Xu, YJ; Zhang, N; Zhang, ZX | 1 |
| Chen, XR; Li, FY; Li, SY; Mao, H; Wang, ZL; Yi, Q | 1 |
| Jin, Y; Wang, C | 1 |
1 trial(s) available for triptolide and Asthma
| Article | Year |
|---|---|
[Effect of tripterygium polyglucoside on T-lymphocyte subsets and serum interleukin-5 level in asthma patients].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Asthma; CD4-CD8 Ratio; Diterpenes; Drugs, Chinese Herbal; Epoxy Compounds; Female; Glucosides; Humans; Immunosuppressive Agents; Interleukin-5; Male; Middle Aged; Phenanthrenes; Phytotherapy; T-Lymphocyte Subsets; Tripterygium | 2001 |
13 other study(ies) available for triptolide and Asthma
| Article | Year |
|---|---|
The Effects of Nebulized Inhaled Triptolide on Airway Inflammation in a Mouse Model of Asthma.
Topics: Animals; Asthma; Cytokines; Dexamethasone; Disease Models, Animal; Inflammation; Interleukin-17; Mice; Mice, Inbred BALB C | 2023 |
Triptolide inhibits PDGF-induced proliferation of ASMCs through G0/G1 cell cycle arrest and suppression of the AKT/NF-κB/cyclinD1 signaling pathway.
Topics: Airway Remodeling; Animals; Asthma; Bronchi; Cell Proliferation; Cells, Cultured; Chromones; Cyclin D1; Diterpenes; Epoxy Compounds; G1 Phase Cell Cycle Checkpoints; Humans; Morpholines; Myocytes, Smooth Muscle; NF-kappa B; Phenanthrenes; Phosphatidylinositol 3-Kinases; Phosphorylation; Platelet-Derived Growth Factor; Primary Cell Culture; Proto-Oncogene Proteins c-akt; Pyrrolidines; Rats; Signal Transduction; Thiocarbamates | 2020 |
Triptolide inhibits TGF-β1-induced cell proliferation in rat airway smooth muscle cells by suppressing Smad signaling.
Topics: Airway Remodeling; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Asthma; Cell Proliferation; Cells, Cultured; Diterpenes; Epoxy Compounds; Immunosuppressive Agents; Male; Myocytes, Smooth Muscle; Phenanthrenes; Phosphorylation; Rats; Rats, Sprague-Dawley; S Phase Cell Cycle Checkpoints; Signal Transduction; Smad2 Protein; Smad3 Protein; Smad7 Protein; Transforming Growth Factor beta1 | 2015 |
Triptolide suppresses airway goblet cell hyperplasia and Muc5ac expression via NF-κB in a murine model of asthma.
Topics: Airway Remodeling; Animals; Asthma; Blotting, Western; Bronchi; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Diterpenes; Epoxy Compounds; Female; Goblet Cells; Hyperplasia; Hypertrophy; Mice, Inbred BALB C; Mucin 5AC; Mucus; NF-kappa B; Phenanthrenes; Phosphorylation; RNA, Messenger; Transcription Factor RelA | 2015 |
[Effect of triptolide on airway remodeling and the expression of phosphoinositide 3-kinases in asthmatic rats].
Topics: Airway Remodeling; Animals; Asthma; Diterpenes; Epoxy Compounds; Male; Phenanthrenes; Phosphatidylinositol 3-Kinase; Rats; Rats, Sprague-Dawley; Signal Transduction | 2007 |
[The effect of triptolide on the expression of BCL-2, ICE in pulmonary tissue of asthmatic guinea pig].
Topics: Animals; Asthma; Caspases; Disease Models, Animal; Diterpenes; Epoxy Compounds; Guinea Pigs; Interleukin-1 Receptor-Associated Kinases; Lung; Male; Phenanthrenes; Proto-Oncogene Proteins c-bcl-2; Tripterygium | 2001 |
The effects of triptolide on airway remodelling and transforming growth factor-β₁/Smad signalling pathway in ovalbumin-sensitized mice.
Topics: Airway Remodeling; Allergens; Animals; Asthma; Blotting, Western; Bronchoalveolar Lavage Fluid; Dexamethasone; Disease Models, Animal; Diterpenes; Enzyme-Linked Immunosorbent Assay; Epoxy Compounds; Female; Immunosuppressive Agents; Mice; Mice, Inbred BALB C; Ovalbumin; Phenanthrenes; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Smad Proteins; Transforming Growth Factor beta1 | 2011 |
[Effect of triptolide on airway smooth muscle proliferation and the expression of nuclear factor-kappa B, Bcl-2 in asthmatic rats].
Topics: Airway Remodeling; Animals; Apoptosis; Asthma; Bronchi; Diterpenes; Epoxy Compounds; Male; Myocytes, Smooth Muscle; NF-kappa B; Phenanthrenes; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley | 2010 |
[The effect of triptolide on the proliferation of airway smooth muscle and the expression of c-fos and c-jun in asthmatic rats].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bronchi; Cell Division; Diterpenes; Epoxy Compounds; Gene Expression Regulation; Male; Muscle, Smooth; Phenanthrenes; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2002 |
[Effect of Tripterygium wilfordii on Th1, Th2 cytokines production in asthma patients].
Topics: Adult; Asthma; Cells, Cultured; Diterpenes; Drugs, Chinese Herbal; Epoxy Compounds; Female; Glucosides; Humans; Interferon-gamma; Leukocytes, Mononuclear; Male; Middle Aged; Phenanthrenes; Phytotherapy; T-Lymphocytes, Helper-Inducer; Tripterygium | 2001 |
[Regulatory function of nuclear factor kappa B on lymphocyte proliferation and apoptosis in bronchial asthmatic rats and effect of triptolide on the regulation].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Asthma; Cell Division; Dexamethasone; Diterpenes; Epoxy Compounds; Lung; Lymphocytes; Male; NF-kappa B; Phenanthrenes; Random Allocation; Rats; Rats, Wistar; Transcription Factor RelA | 2004 |
Mycophenolate mofetil and triptolide alleviating airway inflammation in asthmatic model mice partly by inhibiting bone marrow eosinophilopoiesis.
Topics: Animals; Asthma; Bone Marrow; Diterpenes; Eosinophils; Epoxy Compounds; Hematopoiesis; Immunosuppressive Agents; Interleukin-5; Male; Mice; Mice, Inbred BALB C; Mycophenolic Acid; Phenanthrenes; Receptors, CCR3 | 2008 |
[mRNA expression of granulocyte-macrophage colony-stimulating factor in airway tissues of asthma guinea pigs: effect of triptolide].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Diterpenes; Epoxy Compounds; Granulocyte-Macrophage Colony-Stimulating Factor; Guinea Pigs; Ovalbumin; Phenanthrenes; RNA, Messenger | 1997 |