Page last updated: 2024-09-02

triptolide and Asthma

triptolide has been researched along with Asthma in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.14)18.2507
2000's7 (50.00)29.6817
2010's4 (28.57)24.3611
2020's2 (14.29)2.80

Authors

AuthorsStudies
Chen, H; Han, L; Miao, Y; Wei, L; Zhang, Z1
Chen, M; He, S; Huang, L; Liang, R; Lin, X; Lv, Z1
Chen, M; Huang, L; Jiang, S; Liang, R; Lin, X; Lv, Z; Shi, J; Zhang, W2
Fang, CS; Liu, XS; Mo, BW; Wang, CM; Xiong, WN; Xu, YJ; Zhang, ZX1
Guo, AY; Guo, XM; Yan, SZ1
Chen, M; Jiang, S; Lv, Z1
Chen, MX; Huang, JW; Lin, Y; Mo, BW; Wang, CM; Wei, JH; Xu, Q; Zeng, JR; Zhou, Y1
He, J; Liang, B; Song, Z; Zhang, Y1
Lin, KX; Qian, GS; Wang, CZ1
Wang, XH; Zhang, ZY1
Xu, YJ; Zhang, N; Zhang, ZX1
Chen, XR; Li, FY; Li, SY; Mao, H; Wang, ZL; Yi, Q1
Jin, Y; Wang, C1

Trials

1 trial(s) available for triptolide and Asthma

ArticleYear
[Effect of tripterygium polyglucoside on T-lymphocyte subsets and serum interleukin-5 level in asthma patients].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2001, Volume: 21, Issue:1

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Asthma; CD4-CD8 Ratio; Diterpenes; Drugs, Chinese Herbal; Epoxy Compounds; Female; Glucosides; Humans; Immunosuppressive Agents; Interleukin-5; Male; Middle Aged; Phenanthrenes; Phytotherapy; T-Lymphocyte Subsets; Tripterygium

2001

Other Studies

13 other study(ies) available for triptolide and Asthma

ArticleYear
The Effects of Nebulized Inhaled Triptolide on Airway Inflammation in a Mouse Model of Asthma.
    Canadian respiratory journal, 2023, Volume: 2023

    Topics: Animals; Asthma; Cytokines; Dexamethasone; Disease Models, Animal; Inflammation; Interleukin-17; Mice; Mice, Inbred BALB C

2023
Triptolide inhibits PDGF-induced proliferation of ASMCs through G0/G1 cell cycle arrest and suppression of the AKT/NF-κB/cyclinD1 signaling pathway.
    European journal of pharmacology, 2020, Jan-15, Volume: 867

    Topics: Airway Remodeling; Animals; Asthma; Bronchi; Cell Proliferation; Cells, Cultured; Chromones; Cyclin D1; Diterpenes; Epoxy Compounds; G1 Phase Cell Cycle Checkpoints; Humans; Morpholines; Myocytes, Smooth Muscle; NF-kappa B; Phenanthrenes; Phosphatidylinositol 3-Kinases; Phosphorylation; Platelet-Derived Growth Factor; Primary Cell Culture; Proto-Oncogene Proteins c-akt; Pyrrolidines; Rats; Signal Transduction; Thiocarbamates

2020
Triptolide inhibits TGF-β1-induced cell proliferation in rat airway smooth muscle cells by suppressing Smad signaling.
    Experimental cell research, 2015, Feb-15, Volume: 331, Issue:2

    Topics: Airway Remodeling; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Asthma; Cell Proliferation; Cells, Cultured; Diterpenes; Epoxy Compounds; Immunosuppressive Agents; Male; Myocytes, Smooth Muscle; Phenanthrenes; Phosphorylation; Rats; Rats, Sprague-Dawley; S Phase Cell Cycle Checkpoints; Signal Transduction; Smad2 Protein; Smad3 Protein; Smad7 Protein; Transforming Growth Factor beta1

2015
Triptolide suppresses airway goblet cell hyperplasia and Muc5ac expression via NF-κB in a murine model of asthma.
    Molecular immunology, 2015, Volume: 64, Issue:1

    Topics: Airway Remodeling; Animals; Asthma; Blotting, Western; Bronchi; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Diterpenes; Epoxy Compounds; Female; Goblet Cells; Hyperplasia; Hypertrophy; Mice, Inbred BALB C; Mucin 5AC; Mucus; NF-kappa B; Phenanthrenes; Phosphorylation; RNA, Messenger; Transcription Factor RelA

2015
[Effect of triptolide on airway remodeling and the expression of phosphoinositide 3-kinases in asthmatic rats].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2007, Volume: 23, Issue:3

    Topics: Airway Remodeling; Animals; Asthma; Diterpenes; Epoxy Compounds; Male; Phenanthrenes; Phosphatidylinositol 3-Kinase; Rats; Rats, Sprague-Dawley; Signal Transduction

2007
[The effect of triptolide on the expression of BCL-2, ICE in pulmonary tissue of asthmatic guinea pig].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2001, Volume: 17, Issue:3

    Topics: Animals; Asthma; Caspases; Disease Models, Animal; Diterpenes; Epoxy Compounds; Guinea Pigs; Interleukin-1 Receptor-Associated Kinases; Lung; Male; Phenanthrenes; Proto-Oncogene Proteins c-bcl-2; Tripterygium

2001
The effects of triptolide on airway remodelling and transforming growth factor-β₁/Smad signalling pathway in ovalbumin-sensitized mice.
    Immunology, 2011, Volume: 132, Issue:3

    Topics: Airway Remodeling; Allergens; Animals; Asthma; Blotting, Western; Bronchoalveolar Lavage Fluid; Dexamethasone; Disease Models, Animal; Diterpenes; Enzyme-Linked Immunosorbent Assay; Epoxy Compounds; Female; Immunosuppressive Agents; Mice; Mice, Inbred BALB C; Ovalbumin; Phenanthrenes; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Smad Proteins; Transforming Growth Factor beta1

2011
[Effect of triptolide on airway smooth muscle proliferation and the expression of nuclear factor-kappa B, Bcl-2 in asthmatic rats].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2010, Volume: 26, Issue:4

    Topics: Airway Remodeling; Animals; Apoptosis; Asthma; Bronchi; Diterpenes; Epoxy Compounds; Male; Myocytes, Smooth Muscle; NF-kappa B; Phenanthrenes; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley

2010
[The effect of triptolide on the proliferation of airway smooth muscle and the expression of c-fos and c-jun in asthmatic rats].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 2002, Volume: 25, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bronchi; Cell Division; Diterpenes; Epoxy Compounds; Gene Expression Regulation; Male; Muscle, Smooth; Phenanthrenes; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2002
[Effect of Tripterygium wilfordii on Th1, Th2 cytokines production in asthma patients].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2001, Volume: 21, Issue:1

    Topics: Adult; Asthma; Cells, Cultured; Diterpenes; Drugs, Chinese Herbal; Epoxy Compounds; Female; Glucosides; Humans; Interferon-gamma; Leukocytes, Mononuclear; Male; Middle Aged; Phenanthrenes; Phytotherapy; T-Lymphocytes, Helper-Inducer; Tripterygium

2001
[Regulatory function of nuclear factor kappa B on lymphocyte proliferation and apoptosis in bronchial asthmatic rats and effect of triptolide on the regulation].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2004, Volume: 24, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Asthma; Cell Division; Dexamethasone; Diterpenes; Epoxy Compounds; Lung; Lymphocytes; Male; NF-kappa B; Phenanthrenes; Random Allocation; Rats; Rats, Wistar; Transcription Factor RelA

2004
Mycophenolate mofetil and triptolide alleviating airway inflammation in asthmatic model mice partly by inhibiting bone marrow eosinophilopoiesis.
    International immunopharmacology, 2008, Volume: 8, Issue:7

    Topics: Animals; Asthma; Bone Marrow; Diterpenes; Eosinophils; Epoxy Compounds; Hematopoiesis; Immunosuppressive Agents; Interleukin-5; Male; Mice; Mice, Inbred BALB C; Mycophenolic Acid; Phenanthrenes; Receptors, CCR3

2008
[mRNA expression of granulocyte-macrophage colony-stimulating factor in airway tissues of asthma guinea pigs: effect of triptolide].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 1997, Volume: 20, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Diterpenes; Epoxy Compounds; Granulocyte-Macrophage Colony-Stimulating Factor; Guinea Pigs; Ovalbumin; Phenanthrenes; RNA, Messenger

1997