Page last updated: 2024-09-02

triptolide and Allergic Encephalomyelitis

triptolide has been researched along with Allergic Encephalomyelitis in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fan, HC; Guo, MF; Ji, N; Liang, LY; Ma, CG; Ren, XR; Sun, YS; Yu, JZ1
Kizelsztein, P; Komarnytsky, S; Raskin, I1
van Eden, W1
Dong, JR; Fu, YF; He, PL; Li, YC; Ni, J; Tang, W; Wan, H; Yang, YF; Zhong, XG; Zhou, R; Zhou, Y; Zhu, YN; Zuo, JP1
Feng, D; Mei, Y; Wang, Y; Xu, L1

Other Studies

5 other study(ies) available for triptolide and Allergic Encephalomyelitis

ArticleYear
[Suppression of murine EAE by triptolide is related to downregulation of INF-gamma and upregulation of IL-10 secretion in splenic lymphocytes].
    Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2009, Volume: 25, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Proliferation; Cell Survival; Cells, Cultured; Culture Media, Conditioned; Diterpenes; Down-Regulation; Encephalomyelitis, Autoimmune, Experimental; Enzyme-Linked Immunosorbent Assay; Epoxy Compounds; Female; Interferon-gamma; Interleukin-10; Interleukin-17; Interleukin-4; Lymphocytes; Mice; Mice, Inbred C57BL; Myelin Proteins; Myelin-Associated Glycoprotein; Myelin-Oligodendrocyte Glycoprotein; Peptide Fragments; Phenanthrenes; Random Allocation; Spinal Cord; Spleen; Up-Regulation

2009
Oral administration of triptolide ameliorates the clinical signs of experimental autoimmune encephalomyelitis (EAE) by induction of HSP70 and stabilization of NF-kappaB/IkappaBalpha transcriptional complex.
    Journal of neuroimmunology, 2009, Dec-10, Volume: 217, Issue:1-2

    Topics: Administration, Oral; Analysis of Variance; Animals; Cell Line, Transformed; Cytokines; Cytoplasm; Disease Models, Animal; Diterpenes; Encephalomyelitis, Autoimmune, Experimental; Epoxy Compounds; HSP70 Heat-Shock Proteins; I-kappa B Proteins; Immunoprecipitation; Immunosuppressive Agents; Lymph Nodes; Macrophages; Mice; Myelin Proteolipid Protein; NF-kappa B; NF-KappaB Inhibitor alpha; Peptide Fragments; Phenanthrenes; Phosphorylation; Phytotherapy; RNA, Messenger; Signal Transduction; Time Factors; Tripterygium; Up-Regulation

2009
Protective and therapeutic effect of triptolide in EAE explained by induction of major stress protein HSP70.
    Journal of neuroimmunology, 2009, Dec-10, Volume: 217, Issue:1-2

    Topics: Animals; Diterpenes; Encephalomyelitis, Autoimmune, Experimental; Epoxy Compounds; Gene Expression Regulation; HSP70 Heat-Shock Proteins; Immunosuppressive Agents; Mice; Phenanthrenes

2009
(5R)-5-hydroxytriptolide (LLDT-8), a novel triptolide derivative, prevents experimental autoimmune encephalomyelitis via inhibiting T cell activation.
    Journal of neuroimmunology, 2006, Volume: 175, Issue:1-2

    Topics: Amino Acid Sequence; Animals; Cell Proliferation; Diterpenes; Encephalomyelitis, Autoimmune, Experimental; Epoxy Compounds; Female; Immunosuppressive Agents; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Phenanthrenes; T-Lymphocytes

2006
Triptolide modulates T-cell inflammatory responses and ameliorates experimental autoimmune encephalomyelitis.
    Journal of neuroscience research, 2008, Aug-15, Volume: 86, Issue:11

    Topics: Animals; Blotting, Western; Cell Proliferation; Cytokines; Demyelinating Diseases; Diterpenes; Electrophoretic Mobility Shift Assay; Encephalomyelitis, Autoimmune, Experimental; Epoxy Compounds; Forkhead Transcription Factors; Gene Expression; Immunosuppressive Agents; Inflammation; Leukocytes, Mononuclear; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Phenanthrenes; Reverse Transcriptase Polymerase Chain Reaction; Spinal Cord; T-Lymphocytes

2008