triptolide has been researched along with Adverse Drug Event in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 5 (83.33) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, GF; Hu, YQ; Huang, K; Liu, CH; Liu, YT; Wang, YL; Yang, T; Zhou, H | 1 |
| Dong, H; Lin, R; Liu, P; Lu, J; Sun, J; Wen, F; Zhang, Y; Zhu, L | 1 |
| Chen, X; Li, M; Liu, C; Luo, Q; Qiu, F; Sun, X; Tao, Y | 1 |
| Chen, X; Du, T; Gong, H; Guo, L; Hou, Z; Ji, M; Li, H; Li, W; Wang, M; Wang, W; Wei, S; Yan, M; You, S; Zhang, B | 1 |
| Cui, D; Fu, R; Liu, W; Ma, W; Tang, Y; Xu, D; Yan, C; Yue, S | 1 |
| Hu, Q; Huang, SY; Jia, LL; Jin, J; Su, HZ; Tan, QY; Xiao, J; Zhang, J; Zhu, SN | 1 |
1 review(s) available for triptolide and Adverse Drug Event
| Article | Year |
|---|---|
Recent advances in the pharmacological applications and liver toxicity of triptolide.
Topics: Chemical and Drug Induced Liver Injury; Diterpenes; Drug-Related Side Effects and Adverse Reactions; Epoxy Compounds; Hepatitis; Humans; Phenanthrenes | 2023 |
5 other study(ies) available for triptolide and Adverse Drug Event
| Article | Year |
|---|---|
Antibiotic pretreatment promotes orally-administered triptolide absorption and aggravates hepatotoxicity and intestinal injury in mice.
Topics: Animals; Anti-Bacterial Agents; Chemical and Drug Induced Liver Injury; Diterpenes; Drug-Related Side Effects and Adverse Reactions; Epoxy Compounds; Inflammasomes; Liver; Mice; NLR Family, Pyrin Domain-Containing 3 Protein; Phenanthrenes | 2022 |
New mechanism of nephrotoxicity of triptolide: Oxidative stress promotes cGAS-STING signaling pathway.
Topics: Animals; Diterpenes; Drug-Related Side Effects and Adverse Reactions; Epoxy Compounds; Humans; Membrane Proteins; Mice; Nucleotidyltransferases; Oxidative Stress; Phenanthrenes; Signal Transduction | 2022 |
Screening of major hepatotoxic components of Tripterygium wilfordii based on hepatotoxic injury patterns.
Topics: Animals; Chemical and Drug Induced Liver Injury; Drug-Related Side Effects and Adverse Reactions; Mice; RNA, Messenger; Tripterygium; Tumor Necrosis Factor-alpha; Zebrafish | 2023 |
Variable p53/Nrf2 crosstalk contributes to triptolide-induced hepatotoxic process.
Topics: Chemical and Drug Induced Liver Injury; Diterpenes; Drug-Related Side Effects and Adverse Reactions; Epoxy Compounds; Humans; NF-E2-Related Factor 2; Phenanthrenes; Tumor Suppressor Protein p53 | 2023 |
Licorice root extract and magnesium isoglycyrrhizinate protect against triptolide-induced hepatotoxicity via up-regulation of the Nrf2 pathway.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Chemical and Drug Induced Liver Injury; Diterpenes; Down-Regulation; Drug-Related Side Effects and Adverse Reactions; Drugs, Chinese Herbal; Epoxy Compounds; Glycyrrhiza; Humans; Liver; Male; NF-E2-Related Factor 2; Oxidative Stress; Phenanthrenes; Plant Extracts; Plant Roots; Rats; Rats, Wistar; Saponins; Triterpenes; Up-Regulation | 2018 |