Page last updated: 2024-09-02

triptolide and Acute Lymphoid Leukemia

triptolide has been researched along with Acute Lymphoid Leukemia in 2 studies

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Deng, M; Jiang, Z; Kannappan, V; Li, P; Li, Y; Shi, P; Wang, W; Xu, B; Zhao, H1
Gu, L; Huang, M; Liu, T; Tian, D; Zhang, H; Zhou, M1

Other Studies

2 other study(ies) available for triptolide and Acute Lymphoid Leukemia

ArticleYear
Low dose triptolide reverses chemoresistance in adult acute lymphoblastic leukemia cells via reactive oxygen species generation and DNA damage response disruption.
    Oncotarget, 2016, Dec-20, Volume: 7, Issue:51

    Topics: Adolescent; Adult; Aged; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Apoptosis; Caspase 9; Cell Line, Tumor; Cell Proliferation; Checkpoint Kinase 1; Checkpoint Kinase 2; Cytarabine; Diterpenes; DNA Damage; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Epoxy Compounds; Female; Histones; Humans; Inhibitory Concentration 50; Male; Membrane Potential, Mitochondrial; Mice, Inbred NOD; Mice, SCID; Middle Aged; Oxidative Stress; Phenanthrenes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Reactive Oxygen Species; Signal Transduction; Tumor Cells, Cultured; Xenograft Model Antitumor Assays; Young Adult

2016
Triptolide inhibits MDM2 and induces apoptosis in acute lymphoblastic leukemia cells through a p53-independent pathway.
    Molecular cancer therapeutics, 2013, Volume: 12, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Child; Diterpenes; Epoxy Compounds; Humans; Phenanthrenes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Promoter Regions, Genetic; Proto-Oncogene Proteins c-mdm2; Signal Transduction; Transfection; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2013