triptolide has been researched along with Acute Lymphoid Leukemia in 2 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Deng, M; Jiang, Z; Kannappan, V; Li, P; Li, Y; Shi, P; Wang, W; Xu, B; Zhao, H | 1 |
| Gu, L; Huang, M; Liu, T; Tian, D; Zhang, H; Zhou, M | 1 |
2 other study(ies) available for triptolide and Acute Lymphoid Leukemia
| Article | Year |
|---|---|
Low dose triptolide reverses chemoresistance in adult acute lymphoblastic leukemia cells via reactive oxygen species generation and DNA damage response disruption.
Topics: Adolescent; Adult; Aged; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Apoptosis; Caspase 9; Cell Line, Tumor; Cell Proliferation; Checkpoint Kinase 1; Checkpoint Kinase 2; Cytarabine; Diterpenes; DNA Damage; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Epoxy Compounds; Female; Histones; Humans; Inhibitory Concentration 50; Male; Membrane Potential, Mitochondrial; Mice, Inbred NOD; Mice, SCID; Middle Aged; Oxidative Stress; Phenanthrenes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Reactive Oxygen Species; Signal Transduction; Tumor Cells, Cultured; Xenograft Model Antitumor Assays; Young Adult | 2016 |
Triptolide inhibits MDM2 and induces apoptosis in acute lymphoblastic leukemia cells through a p53-independent pathway.
Topics: Antineoplastic Agents, Alkylating; Apoptosis; Child; Diterpenes; Epoxy Compounds; Humans; Phenanthrenes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Promoter Regions, Genetic; Proto-Oncogene Proteins c-mdm2; Signal Transduction; Transfection; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2013 |