Page last updated: 2024-10-19

triphosphoric acid and 2019 Novel Coronavirus Disease

triphosphoric acid has been researched along with 2019 Novel Coronavirus Disease in 8 studies

triphosphoric acid: used as water softener, peptizing agent, emulsifier & dispersing agent; ingredient of cleansers; meat preservative; RN given refers to parent cpd; structure

Research Excerpts

ExcerptRelevanceReference
"Molnupiravir is an antiviral that has shown clinical efficacy against mild-to-moderate COVID-19 but failed to provide benefit to hospitalized patients with severe disease."1.72Why Molnupiravir Fails in Hospitalized Patients. ( Brown, AN; Bulitta, JB; Drusano, GL; Franco, EJ; Hanrahan, KC; Lang, Y; Zhou, J, 2022)
"Favipiravir has discrepant activity against SARS-CoV-2 in vitro, concerns about teratogenicity and pill burden, and an unknown optimal dose."1.62Pharmacokinetic modelling to estimate intracellular favipiravir ribofuranosyl-5'-triphosphate exposure to support posology for SARS-CoV-2. ( Khoo, SH; Owen, A; Pertinez, H; Rajoli, RKR, 2021)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's8 (100.00)2.80

Authors

AuthorsStudies
Gillis, TD1
Bearne, SL1
Song, Z2
Wang, Q1
Bian, L1
An, C2
Cui, B2
Mao, Q2
Wu, X1
He, Q2
Bai, Y2
Liu, J3
Song, L1
Liu, D2
Zhang, J2
Gao, F1
Li, X1
Liang, Z2
Brown, AN1
Lang, Y1
Zhou, J1
Franco, EJ1
Hanrahan, KC1
Bulitta, JB1
Drusano, GL1
Gioia, U1
Tavella, S1
Martínez-Orellana, P1
Cicio, G1
Colliva, A1
Ceccon, M1
Cabrini, M1
Henriques, AC1
Fumagalli, V1
Paldino, A1
Presot, E1
Rajasekharan, S1
Iacomino, N1
Pisati, F1
Matti, V1
Sepe, S1
Conte, MI1
Barozzi, S1
Lavagnino, Z1
Carletti, T1
Volpe, MC1
Cavalcante, P1
Iannacone, M1
Rampazzo, C1
Bussani, R1
Tripodo, C1
Zacchigna, S1
Marcello, A1
d'Adda di Fagagna, F1
Zhang, X1
Li, K1
Cheng, F1
Chen, KL1
Wang, FS1
Hu, WJ1
Chang, L1
Yang, Y1
Wang, X1
Xie, YC1
Shen, JS1
Tan, B1
Pertinez, H1
Rajoli, RKR1
Khoo, SH1
Owen, A1

Other Studies

8 other studies available for triphosphoric acid and 2019 Novel Coronavirus Disease

ArticleYear
Effects of the 5'-Triphosphate Metabolites of Ribavirin, Sofosbuvir, Vidarabine, and Molnupiravir on CTP Synthase Catalysis and Filament Formation: Implications for Repurposing Antiviral Agents against SARS-CoV-2.
    ChemMedChem, 2022, 12-05, Volume: 17, Issue:23

    Topics: Antiviral Agents; COVID-19; Cytidine; Escherichia coli; Humans; Ribavirin; SARS-CoV-2; Sofosbuvir; V

2022
A Short 5'triphosphate RNA nCoV-L Induces a Broad-Spectrum Antiviral Response by Activating RIG-I.
    Viruses, 2022, 11-04, Volume: 14, Issue:11

    Topics: Animals; Antiviral Agents; Cell Line; COVID-19; DEAD Box Protein 58; DEAD-box RNA Helicases; Humans;

2022
Why Molnupiravir Fails in Hospitalized Patients.
    mBio, 2022, 12-20, Volume: 13, Issue:6

    Topics: Antiviral Agents; COVID-19; Humans; SARS-CoV-2

2022
SARS-CoV-2 infection induces DNA damage, through CHK1 degradation and impaired 53BP1 recruitment, and cellular senescence.
    Nature cell biology, 2023, Volume: 25, Issue:4

    Topics: Animals; Cellular Senescence; COVID-19; DNA Damage; Mice; SARS-CoV-2

2023
A Novel Targeted RIG-I Receptor 5'Triphosphate Double Strain RNA-Based Adjuvant Significantly Improves the Immunogenicity of the SARS-CoV-2 Delta-Omicron Chimeric RBD-Dimer Recombinant Protein Vaccine.
    Viruses, 2023, 04-29, Volume: 15, Issue:5

    Topics: ABO Blood-Group System; Adjuvants, Immunologic; Adjuvants, Vaccine; Animals; Antibodies, Neutralizin

2023
Cell-specific genome-scale metabolic modeling of SARS-CoV-2-infected lung to identify antiviral enzymes.
    FEBS open bio, 2023, Volume: 13, Issue:12

    Topics: Antiviral Agents; COVID-19; Dihydroorotate Dehydrogenase; Humans; Lipids; Lung; SARS-CoV-2

2023
Pharmacokinetics and tissue distribution of remdesivir and its metabolites nucleotide monophosphate, nucleotide triphosphate, and nucleoside in mice.
    Acta pharmacologica Sinica, 2021, Volume: 42, Issue:7

    Topics: Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; COVID-19; COVID-19 Drug Treatment; Kidn

2021
Pharmacokinetic modelling to estimate intracellular favipiravir ribofuranosyl-5'-triphosphate exposure to support posology for SARS-CoV-2.
    The Journal of antimicrobial chemotherapy, 2021, 07-15, Volume: 76, Issue:8

    Topics: Amides; Animals; Antiviral Agents; COVID-19; Dogs; Humans; Polyphosphates; Pyrazines; SARS-CoV-2

2021