triphenyltetrazolium has been researched along with Infarction, Middle Cerebral Artery in 128 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (0.78) | 18.2507 |
| 2000's | 86 (67.19) | 29.6817 |
| 2010's | 40 (31.25) | 24.3611 |
| 2020's | 1 (0.78) | 2.80 |
| Authors | Studies |
|---|---|
| Fern, R; Gibson, CL; Janus, J; Kelly, ME; Trotman-Lucas, M | 1 |
| Li, L; Liang, W; Yu, Q | 1 |
| Chen, L; Chen, SR; Li, L; Luo, Y; Ma, H; Pan, HL; Zhang, J; Zhou, JJ | 1 |
| Feng, J; Zhai, Z | 1 |
| He, WM; Peng, YP; Wang, H; Ying-Fu, L | 1 |
| Du, J; Hu, S; Liu, L; Shi, Q; Wang, X; Wu, S; Zhao, M; Zheng, T | 1 |
| Ben, RJ; Chang, CY; Chen, PC; Hwang, LC; Jao, JC; Tzeng, JS | 1 |
| Ates, N; Dillioglugil, MO; Ekici, F; Gurol, G; Karson, A; Kir, HM | 1 |
| Ding, B; Tang, X; Tu, Q; Zhong, W | 1 |
| Dong, DW; Ruan, YW; Wang-Qin, RQ; Xu, AD; Yang, WY; Zhang, YS | 1 |
| Benkovic, SA; Bibb, JA; Calabresi, P; Di Filippo, M; DiNapoli, V; Greengard, P; Huber, JD; Kansy, JW; Meyer, DA; Miller, DB; Plattner, F; Rosen, CL; Tan, Z; Torres-Altoro, MI; Tozzi, A | 1 |
| Deng, J; He, J; Hu, Z; Lei, Q; Liu, J; Lu, W; Song, T; Tao, X; Zhang, J; Zheng, L | 1 |
| Cho, KH; Choi, KH; Kim, BC; Kim, HS; Kim, JT; Kim, KT; Kim, MK; Park, JT; Park, MS | 1 |
| Klebe, D; McBride, DW; Tang, J; Zhang, JH | 1 |
| Blumbergs, PC; Helps, SC; Knox, SJ; Turner, RJ; Vink, R; Wells, AJ | 1 |
| Chen, DX; Chen, YY; Dong, DW; Mai, HC; Zeng, JS; Zhang, YS | 1 |
| Dong, W; Gao, D; Li, F; Li, N; Zhang, X; Zhen, H | 1 |
| Hara, H; Iwama, T; Nonaka, Y; Shimazawa, M; Yoshimura, S | 1 |
| Egashira, N; Fujioka, M; Fujiwara, M; Hayakawa, K; Hazekawa, M; Irie, K; Iwasaki, K; Katsurabayashi, S; Mishima, K; Mishima, S; Orito, K; Takasaki, K | 1 |
| Li, H; Li, WW; Wu, TW | 1 |
| Glendenning, ML; Lovekamp-Swan, T; Schreihofer, DA | 1 |
| Kong, H; Sun, XL; Zeng, XN; Zhou, XQ | 1 |
| Hu, X; Tian, M; Wan, H; Yang, J; Zhang, H; Zhao, C; Zhu, H | 1 |
| Bastan, B; Bouley, J; Bråtane, BT; Fisher, M; Henninger, N; Shea, M | 1 |
| Atif, F; Ishrat, T; Sayeed, I; Stein, DG | 1 |
| Liu, F; McCullough, LD; Schafer, DP | 1 |
| Araki, T; Kato, H; Matsuda, S; Uchida, H; Umeda, M | 1 |
| Li, Q; Li, YJ; Mu, J; Tang, J; Xie, P; Yang, DY | 1 |
| Adair-Kirk, TL; Gidday, JM; Gonzales, ER; Park, TS; Perez, RS; Shah, AR; Stowe, AM | 1 |
| Bastan, B; Bouley, J; Bråtane, BT; Fisher, M; Henninger, N | 1 |
| Chen, Q; Edvinsson, L; Maddahi, A | 1 |
| Furuta, K; Hokamura, K; Ibaraki, K; Maeda, M; Suzuki, M; Thura, M; Umemura, K; Yamamoto, S | 1 |
| Lee, H; Swanson, RA; Tang, XN; van Hoecke, M; Wang, Q; Yenari, MA; Zheng, Z | 1 |
| Gao, X; Shi, XY; Tian, ML; Wang, CC; Xu, HT; Yuan, HB; Zhu, QF; Zou, Z | 1 |
| Cha, DQ; Fang, S; Liang, Y; Liu, LC; Shen, YJ; Shen, YX; Wang, FC; Wang, HP; Yu, YQ; Zhang, JJ | 1 |
| Shen, H; Wang, Y | 1 |
| Hong, JS; Kim, HY; Lee, JJ; Lee, KS; Lee, SR; Park, JW | 1 |
| Baertling, F; Beyer, C; Clarner, T; Dang, J; Denecke, B; Kipp, M; Kirsch, C; Kramer, M | 1 |
| Han, IO; Hwang, JS; Hwang, SY; Kim, JB; Kim, SY; Lee, JK; Oh, ES; Oh, S; Shin, JA; Shin, JH | 1 |
| Chen, C; Duan, W; Han, J; Hu, Q; Khatibi, NH; Li, L; Wang, K; Yang, L; Zhang, JH; Zhou, C | 1 |
| Cao, H; Chu, XP; Duan, B; Hansen, J; Huang, Y; Simon, RP; Wang, YZ; Xiong, ZG; Xu, TL; Yang, T; Yu, Y; Zhu, MX | 1 |
| Chiang, T; Chou, WH; Messing, RO | 1 |
| Bai, Y; Chen, L; Li, L; Qi, J; Qi, Z; Sun, K; Yang, R; Zhang, Z; Zhou, L | 1 |
| Joshita, H; Miyazaki, H; Shiokawa, Y; Tsubokawa, T | 1 |
| Buchholz, J; Charles, S; Chiu, J; Jadhav, V; Khatibi, NH; Tang, J; Zhang, JH | 1 |
| Abulrob, A; Baumann, E; Brunette, E; Slinn, J; Stanimirovic, D | 1 |
| Baĭsa, AE; Burov, SV; Chefu, SG; Leko, MV; Veselkina, OS; Vlasov, TD | 1 |
| Du, Y; Ji, H; Li, L; Li, S; Liu, H; Miao, J; Zhang, X | 1 |
| Arbeloa, J; Gottlieb, M; Matute, C; Pérez-Samartín, A | 1 |
| Chen, C; Chen, Y; Han, J; Hu, Q; Khatibi, NH; Li, L; Ma, D; Yan, J; Zhou, C | 1 |
| Chan, WM; Dong, J; Huang, Y; Qi, W; Wai, MS; Wang, C; Wang, YX; Yew, DT; Yu, WH; Zhang, L; Zhao, F | 1 |
| Defazio, RA; Deng, X; Ginsberg, MD; Obenaus, A; Zhao, W | 1 |
| Feng, J; Li, Q; Qin, X; Wang, T; Wu, X | 1 |
| Hanif, K; Sharma, G; Singh, N | 1 |
| Ahmad, A; Crupi, R; Cuzzocrea, S; Esposito, E; Genovese, T; Impellizzeri, D; Marino, A; Velardi, E | 1 |
| Chen, L; Hong, J; Tao, J; Wu, G; Zou, Y | 1 |
| Coma-del-Corral, MJ; Ruiz-Crespo, S; Trejo-Gabriel-Galán, JM | 1 |
| Galagudza, M; Melnikova, E; Shmonin, A; Vlasov, T | 1 |
| Arumugam, TV; Asano, M; Chunduri, P; Coulthard, MG; Cully, TR; Jo, DG; Launikonis, BS; Lok, KZ; Manzanero, S; Naruse, C; Pavlovski, D; Sobey, CG; Thundyil, J; Widiapradja, A | 1 |
| Isshiki, A; Matsumoto, S; Watanabe, Y; Wieloch, T | 1 |
| Bähr, M; Hermann, DM; Holzmüller, H; Kilic, E; Kilic, U; Kügler, S; Schmeer, C | 1 |
| Li, JH; Li, W; Lin, Q; Lu, XC; Massuda, E; Zhang, J | 1 |
| Calvert, JW; Kusaka, I; Nanda, A; Parent, AD; Yin, D; Zhang, JH; Zhou, C | 1 |
| Han, PL; Kim, JB; Lee, JK; Piao, CS | 1 |
| Day, AL; Fan, T; Hayes, R; Johnson, E; Osteen, B; Simpkins, JW; Yang, SH | 1 |
| Bähr, M; Kilic, E; Kilic, U; Yulug, B | 1 |
| Ataus, SA; Balkan, S; Locke, KW; Onal, MZ; Ozdem, SS | 1 |
| Abumiya, T; Ikeda, J; Iwasaki, Y; Kobayashi, T; Kuroda, S; Shichinohe, H; Yoshimoto, T | 1 |
| Albert, M; Bagdy, E; Gigler, G; Hársing, LG; Jurányi, Z; Király, I; Ling, I; Móricz, K; Simó, A; Sólyom, S; Szénási, G; Varga, A | 1 |
| Hwang, P; Jose, R; Lim, T; Ling, E; Lu, J; Moochhala, SM; Ng, I; Ng, KC; Ng, PY; Rumpel, H; Shirhan, MD; Sitoh, YY; Teo, AL; Yap, E | 1 |
| Jain, SK; Joshi, CN; Murthy, PS | 1 |
| Hashi, K; Honmou, O; Houkin, K; Iihoshi, S; Kocsis, JD | 1 |
| Candelario-Jalil, E; Fiebich, BL; García-Cabrera, M; González-Falcón, A; León, OS | 1 |
| Cestari, LA; Lima, KC; Milani, H; Schilichting, CL; Sekiyama, JY; Silva, FM | 1 |
| Gilg, AG; Giri, S; Jatana, M; Khan, M; Sekhon, B; Sekhon, C; Singh, AK; Singh, I | 1 |
| Egashira, N; Fujiwara, M; Hayakawa, K; Iwasaki, K; Kimura, H; Mishima, K | 1 |
| Gressens, P; Rogido, M; Sola, A; Wen, TC | 1 |
| Ahlström, H; Akterin, S; Ericsson, A; Gerwins, P; Lennmyr, F; Terént, A | 1 |
| Cui, L; Langsdorf, J; Wei, L; Ying, DJ; Yu, SP | 1 |
| Chen, GJ; Harvey, BK; Shen, H; Wang, Y; Yoshida, Y | 1 |
| Gross, GJ; Hillard, CJ; Muthian, S; Rademacher, DJ; Roelke, CT | 1 |
| Lu, Q; Wong, PT; Zhu, YZ | 1 |
| Chen, F; Marchal, G; Nagai, N; Ni, Y; Peeters, R; Suzuki, Y | 1 |
| Abe, K; Egashira, N; Fujiwara, M; Hasebe, N; Hayakawa, K; Ikeda, T; Inui, K; Iwasaki, K; Mishima, K; Takamatsu, F; Yasuda, H | 1 |
| Abe, T; Cetinalp, NE; Fujiki, M; Inoue, R; Kobayashi, H; Nagai, Y; Uchida, S | 1 |
| Cheng, H; Chih, CL; Chu, YC; Huang, SS; Huang, WC; Lin, HC; Lin, MJ; Lin, SM; Tsai, MJ; Tsai, SK | 1 |
| Black, MD; Ji, Z; Maynard, KI; Sukoff, SJ; Wettstein, JG | 1 |
| Butler, TL; Collier, L; Collier, SN; De Mesquita, D; Duckworth, EA; Pennypacker, KR | 1 |
| Hua, Y; Keep, RF; Pecina, S; Schallert, T; Wu, J; Xi, G; Yang, S | 1 |
| Hayashi, S; Kajimoto, T; Kohmura, E; Saito, N; Ueyama, T; Yagi, K | 1 |
| Hara, H; Morimoto, N; Nagai, H; Shimazawa, M; Yamashima, T | 1 |
| Bath, PM; Constantin, D; Gibson, CL; Murphy, SP; Prior, MJ | 1 |
| Andrási, F; Berzsenyi, P; Erdo, F | 1 |
| Dunbar, JC; Rafols, J; Rizk, NN | 1 |
| Bardutzky, J; Bouley, J; Duong, TQ; Fisher, M; Henninger, N; Shen, Q | 1 |
| Doyle, KM; Henman, MC; Li, J; Shaw, GG; Tatlisumak, T | 1 |
| Craft, TK; DeVries, AC; Glasper, ER; Hurn, PD; McCullough, L; Otsuka, T; Sugo, N; Zhang, N | 1 |
| Han, PL; Kim, JB; Kim, SY; Lee, JK; Lee, KW; Yu, YM | 1 |
| Gao, F; Nukui, H; Sugita, M | 1 |
| Chung, MA; Kim, HJ; Ko, MJ; Lee, JE; Lee, JY; Lee, ST | 1 |
| Connell, B; Saleh, TM; Wilson, BC | 1 |
| Dayal, M; Frydman, J; Giffard, RG; Ouyang, YB; Sun, Y; Xu, L; Yang, CF | 1 |
| Choo, YK; Jung, KY; Kim, JS; Kim, SM; Kwak, DH; Lee, DH; Lee, SU; Seo, BB | 1 |
| Abe, T; Fujiki, M; Kobayashi, H; Nagai, Y; Uchida, S | 1 |
| Chen, M; Cox, S; Fernandez, J; Hogan, L; Howells, DW; Rewell, S; Spratt, NJ; van Raay, L | 1 |
| Elger, B; Gieseler, M; Huth, A; Schmuecker, O; Schumann, I; Seltz, A | 1 |
| Calvert, JW; Shimamura, N; Solaroglu, I; Tsubokawa, T; Yamaguchi-Okada, M; Yata, K; Zhang, JH | 1 |
| Hamai, M; Horiuchi, M; Ide, A; Iwai, M; Mogi, M; Tomochika, H; Tomono, Y | 1 |
| Albert, M; Benedek, A; Gigler, G; Hársing, LG; Jurányi, Z; Lévay, G; Mátyus, P; Móricz, K; Szénási, G | 1 |
| Cam, E; Hüdaoglu, O; Kilic, E; Schäbitz, WR; Yildiz, A; Yulug, B | 1 |
| Britz, GW; Meno, JR; Ngai, AC; Nguyen, TS | 1 |
| Bouley, J; Fisher, M; Henninger, N | 1 |
| Fan, XJ; Jiang, ZL; Ke, KF; Li, X; Wang, GH; Zhang, L | 1 |
| Abe, K; Egashira, N; Fujioka, M; Fujiwara, M; Hasebe, N; Hayakawa, K; Hazekawa, M; Irie, K; Iwasaki, K; Mishima, K; Nozako, M; Orito, K | 1 |
| Hamada, H; Harada, K; Honmou, O; Houkin, K; Kocsis, JD; Onda, T | 1 |
| Chu, X; Fu, X; Qi, C; Zou, L | 1 |
| Brown, CM; Dela Cruz, CD; Wise, PM; Yang, E | 1 |
| Feustel, PJ; Kimelberg, HK; Zhang, H; Zhang, Y | 1 |
| Candelario-Jalil, E; Fiebich, BL; Muñoz, E | 1 |
| Heo, JH; Kim, EH; Kim, SH; Lee, BI | 1 |
| Bakar, M; Ozan, E; Yulug, B | 1 |
| Chen, G; Frøkiaer, J; Nielsen, S; Pang, Q; Pedersen, M; Si, Z; Stødkilde-Jørgensen, H | 1 |
| Lee, TH; Yoon, JG | 1 |
| Jung, HH; Lee, JJ; Li, L; Zuo, Z | 1 |
| Fisher, M; Li, F; Omae, T | 1 |
| Banigesh, A; Baziany, A; Hemmings, SJ; Khan, SH; Shuaib, A | 1 |
| Chan, YC; Chen, IL; Cheng, FC; Lee, MS; Wang, MF; Yang, DY | 1 |
| Bähr, M; Hermann, DM; Kilic, E | 1 |
128 other study(ies) available for triphenyltetrazolium and Infarction, Middle Cerebral Artery
| Article | Year |
|---|---|
An alternative surgical approach reduces variability following filament induction of experimental stroke in mice.
Topics: Analgesia; Animals; Anisotropy; Brain Ischemia; Carotid Arteries; Cerebrovascular Circulation; Diffusion Magnetic Resonance Imaging; Imaging, Three-Dimensional; Infarction, Middle Cerebral Artery; Magnetic Resonance Imaging; Male; Mice, Inbred C57BL; Organ Size; Reperfusion Injury; Stroke; Tetrazolium Salts | 2017 |
Use of 2,3,5-triphenyltetrazolium chloride-stained brain tissues for immunofluorescence analyses after focal cerebral ischemia in rats.
Topics: Animals; Brain; Coloring Agents; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation; Histological Techniques; Infarction, Middle Cerebral Artery; Male; Rats, Sprague-Dawley; Stroke; Tetrazolium Salts | 2018 |
Focal Cerebral Ischemia and Reperfusion Induce Brain Injury Through α2δ-1-Bound NMDA Receptors.
Topics: Animals; Brain Injuries; Brain Ischemia; Calcium Channels; Hippocampus; Infarction, Middle Cerebral Artery; Male; Mice, Knockout; Neurons; Neuroprotective Agents; Receptors, N-Methyl-D-Aspartate; Stroke; Tetrazolium Salts | 2018 |
Left-right asymmetry influenced the infarct volume and neurological dysfunction following focal middle cerebral artery occlusion in rats.
Topics: Animals; Brain Ischemia; Cerebrum; Coloring Agents; Disease Models, Animal; Infarction, Middle Cerebral Artery; Male; Maze Learning; Middle Cerebral Artery; Nervous System Diseases; Random Allocation; Rats, Sprague-Dawley; Reperfusion; Reperfusion Injury; Tetrazolium Salts; Walking | 2018 |
Delayed treatment of α5 GABAA receptor inverse agonist improves functional recovery by enhancing neurogenesis after cerebral ischemia-reperfusion injury in rat MCAO model.
Topics: Animals; Disease Models, Animal; Fluorescent Antibody Technique; GABA-A Receptor Agonists; Imidazoles; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Male; Neurogenesis; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Tetrazolium Salts | 2019 |
Readout-segmented echo-planar diffusion-weighted MR at 3.0 T for the evaluation the effect of low-intensity transcranial ultrasound on stroke in a rat model.
Topics: Algorithms; Animals; Disease Models, Animal; Infarction, Middle Cerebral Artery; Magnetic Resonance Imaging; Male; Rats; Rats, Sprague-Dawley; Stroke; Tetrazolium Salts; Ultrasonic Therapy; Ultrasonic Waves | 2020 |
Longitudinal investigation of ischemic stroke using magnetic resonance imaging: Animal model.
Topics: Angiography, Digital Subtraction; Animals; Brain Ischemia; Carotid Artery Injuries; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Infarction, Middle Cerebral Artery; Longitudinal Studies; Male; Rats; Rats, Sprague-Dawley; Stroke; Tetrazolium Salts | 2019 |
The effects of vagal nerve stimulation in focal cerebral ischemia and reperfusion model.
Topics: Animals; Behavior, Animal; Brain Ischemia; Cerebral Infarction; Coloring Agents; Electrodes, Implanted; Glutathione; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Reperfusion Injury; Superoxide Dismutase; Tetrazolium Salts; Vagus Nerve Stimulation | 2013 |
NADPH oxidase mediates the expression of MMP-9 in cerebral tissue after ischemia-reperfusion damage.
Topics: Acetophenones; Animals; Blotting, Western; Brain; Brain Ischemia; Enzyme Inhibitors; Infarction, Middle Cerebral Artery; Male; Matrix Metalloproteinase 9; Membrane Glycoproteins; NADPH Oxidase 2; NADPH Oxidases; Polymerase Chain Reaction; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; RNA, Messenger; Tetrazolium Salts; Up-Regulation | 2014 |
Hyperphosphorylation of tau protein in the ipsilateral thalamus after focal cortical infarction in rats.
Topics: Animals; Cerebral Cortex; Cerebral Infarction; Disease Models, Animal; Functional Laterality; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Male; Phosphopyruvate Hydratase; Phosphorylation; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; tau Proteins; Tetrazolium Salts; Thalamus; Time Factors | 2014 |
Ischemic stroke injury is mediated by aberrant Cdk5.
Topics: Animals; Calpain; Cell Death; Corpus Striatum; Cyclin-Dependent Kinase 5; Disease Models, Animal; Estrogens; Female; Glial Fibrillary Acidic Protein; Hypoxia; In Vitro Techniques; Infarction, Middle Cerebral Artery; Male; Mice, Knockout; Nerve Tissue Proteins; Nervous System Diseases; Neurons; Phosphotransferases; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Time Factors; Tissue Plasminogen Activator | 2014 |
HspB8 expression in brain tissue after cerebral ischemic reperfusion and atorvastatin intervention in Sprague-Dawley rats.
Topics: Animals; Apoptosis; Atorvastatin; Blotting, Western; Brain Ischemia; Cerebral Cortex; Disease Models, Animal; Heat-Shock Proteins; Heptanoic Acids; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Male; Neurons; Neuroprotective Agents; Pyrroles; Random Allocation; Rats, Sprague-Dawley; Reperfusion Injury; Severity of Illness Index; Tetrazolium Salts | 2015 |
Alpha-lipoic acid treatment is neurorestorative and promotes functional recovery after stroke in rats.
Topics: Animals; Biomarkers; Brain; Brain Infarction; Bromodeoxyuridine; Cell Proliferation; Doublecortin Protein; Glial Fibrillary Acidic Protein; Glucose; Immunohistochemistry; Infarction, Middle Cerebral Artery; Inflammation; Male; Nestin; Positron-Emission Tomography; Rats, Sprague-Dawley; Recovery of Function; RNA, Messenger; SOXB1 Transcription Factors; Staining and Labeling; Stroke; Tetrazolium Salts; Thioctic Acid | 2015 |
Correcting for Brain Swelling's Effects on Infarct Volume Calculation After Middle Cerebral Artery Occlusion in Rats.
Topics: Algorithms; Animals; Brain; Brain Edema; Disease Models, Animal; Functional Laterality; Image Processing, Computer-Assisted; Infarction, Middle Cerebral Artery; Male; Rats; Rats, Sprague-Dawley; Reperfusion; Tetrazolium Salts; Time Factors | 2015 |
Elevated Intracranial Pressure and Cerebral Edema following Permanent MCA Occlusion in an Ovine Model.
Topics: Animals; Brain; Brain Edema; Disease Models, Animal; Female; Infarction, Middle Cerebral Artery; Intracranial Hypertension; Magnetic Resonance Imaging; Oxygen; Random Allocation; Sheep, Domestic; Stroke; Tetrazolium Salts | 2015 |
[Expression pattern of beta-amyloid in the peri-infarct area and ipsilateral thalamus of rats after focal cerebral cortex infarction].
Topics: Amyloidogenic Proteins; Animals; Brain Ischemia; Infarction, Middle Cerebral Artery; Male; Neurons; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thalamus | 2016 |
Resveratrol attenuates ischemic brain damage in the delayed phase after stroke and induces messenger RNA and protein express for angiogenic factors.
Topics: Angiogenic Proteins; Animals; Blotting, Western; Brain; Coloring Agents; Disease Models, Animal; Drug Administration Schedule; Immunohistochemistry; Infarction, Middle Cerebral Artery; Male; Matrix Metalloproteinase 2; Mice; Mice, Inbred BALB C; Microcirculation; Motor Activity; Neovascularization, Physiologic; Neuroprotective Agents; Reperfusion Injury; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Stroke; Tetrazolium Salts; Time Factors; Up-Regulation; Vascular Endothelial Growth Factor A | 2008 |
Combination effects of normobaric hyperoxia and edaravone on focal cerebral ischemia-induced neuronal damage in mice.
Topics: Animals; Antipyrine; Blood Pressure; Cell Death; Cerebral Infarction; Disease Models, Animal; Edaravone; Free Radical Scavengers; Hyperbaric Oxygenation; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Male; Mice; Neurologic Examination; Neurons; Tetrazolium Salts | 2008 |
Cannabidiol prevents a post-ischemic injury progressively induced by cerebral ischemia via a high-mobility group box1-inhibiting mechanism.
Topics: Analysis of Variance; Animals; Blood Pressure; Brain Injuries; Calcium-Binding Proteins; Cannabidiol; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Gene Expression Regulation; Glial Fibrillary Acidic Protein; HMGB1 Protein; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Male; Mice; Microfilament Proteins; Motor Activity; Neurologic Examination; Peroxidase; Phosphopyruvate Hydratase; Reperfusion; Tetrazolium Salts; Time Factors | 2008 |
Netrin-1 attenuates ischemic stroke-induced apoptosis.
Topics: Animals; Apoptosis; Brain Infarction; Cell Movement; Cells, Cultured; Cerebral Cortex; DCC Receptor; Disease Models, Animal; Embryo, Mammalian; Fluoresceins; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Magnetic Resonance Imaging; Male; Mice; Mice, Inbred C57BL; Nerve Growth Factors; Netrin Receptors; Netrin-1; Neurons; Organic Chemicals; Receptors, Cell Surface; Tetrazolium Salts; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Up-Regulation | 2008 |
Protective effect of estrogen in endothelin-induced middle cerebral artery occlusion in female rats.
Topics: Animals; Behavior, Animal; Brain Infarction; Disease Models, Animal; Endothelin-1; Estrogens; Female; Fluoresceins; Infarction, Middle Cerebral Artery; Laser-Doppler Flowmetry; Motor Activity; Neuroprotective Agents; Organic Chemicals; Ovariectomy; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Tetrazolium Salts | 2008 |
Neuroprotective effects of berberine on stroke models in vitro and in vivo.
Topics: Animals; Apoptosis Inducing Factor; Berberine; Brain Infarction; Cell Hypoxia; Cell Survival; Cytochromes c; Disease Models, Animal; Dose-Response Relationship, Drug; Glucose; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred ICR; Neurologic Examination; Neuroprotective Agents; PC12 Cells; Rats; Reperfusion; Tetrazolium Salts | 2008 |
Protective effect of chuanxiongzine-puerarin in a rat model of transient middle cerebral artery occlusion-induced focal cerebral ischemia.
Topics: Animals; Antioxidants; Brain; Gene Expression Regulation; Glucose; Infarction, Middle Cerebral Artery; Interleukin-1; Ischemic Attack, Transient; Isoflavones; Male; Malondialdehyde; Nervous System Diseases; Neuroprotective Agents; Nitric Oxide; Pyrazines; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxide Dismutase; Synaptophysin; Tetrazolium Salts | 2008 |
Laser Doppler flowmetry predicts occlusion but not tPA-mediated reperfusion success after rat embolic stroke.
Topics: Animals; Brain Infarction; Cerebrovascular Circulation; Disease Models, Animal; Infarction, Middle Cerebral Artery; Laser-Doppler Flowmetry; Magnetic Field Therapy; Male; Rats; Rats, Sprague-Dawley; Reperfusion; Tetrazolium Salts; Time Factors; Tissue Plasminogen Activator | 2009 |
Effects of progesterone administration on infarct volume and functional deficits following permanent focal cerebral ischemia in rats.
Topics: Analysis of Variance; Animals; Brain; Hand Strength; Infarction, Middle Cerebral Artery; Male; Motor Activity; Progesterone; Rats; Rats, Sprague-Dawley; Recovery of Function; Rotarod Performance Test; Stroke; Tetrazolium Salts | 2009 |
TTC, fluoro-Jade B and NeuN staining confirm evolving phases of infarction induced by middle cerebral artery occlusion.
Topics: Analysis of Variance; Animals; Brain; Brain Chemistry; Brain Infarction; DNA-Binding Proteins; Fluoresceins; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred C57BL; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Organic Chemicals; Severity of Illness Index; Staining and Labeling; Tetrazolium Salts; Time Factors | 2009 |
Alterations of oxidative stress markers and apoptosis markers in the striatum after transient focal cerebral ischemia in rats.
Topics: Aldehydes; Animals; Apoptosis; Blotting, Western; Corpus Striatum; DNA, Single-Stranded; Immunohistochemistry; Infarction, Middle Cerebral Artery; Male; Nerve Tissue Proteins; Neurons; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Tetrazolium Salts | 2009 |
Albumin ameliorates tissue plasminogen activator-mediated blood-brain barrier permeability and ischemic brain injury in rats.
Topics: Albumins; Analysis of Variance; Animals; Blood-Brain Barrier; Brain Edema; Brain Injuries; Capillary Permeability; Cell Count; Cell Death; Disease Models, Animal; Fibrinolytic Agents; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Male; Neurologic Examination; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tetrazolium Salts; Tissue Plasminogen Activator | 2009 |
Neutrophil elastase and neurovascular injury following focal stroke and reperfusion.
Topics: Analysis of Variance; Animals; Blood Gas Analysis; Blood Pressure; Blood-Brain Barrier; Brain; Brain Edema; Brain Infarction; Cell Adhesion; Disease Models, Animal; Enzyme Inhibitors; Infarction, Middle Cerebral Artery; Laser-Doppler Flowmetry; Leukocyte Elastase; Leukocytes; Male; Matrix Metalloproteinase 9; Mice; Mice, Knockout; Reperfusion Injury; Tetrazolium Salts | 2009 |
Ischemic lesion volume determination on diffusion weighted images vs. apparent diffusion coefficient maps.
Topics: Animals; Brain; Diffusion Magnetic Resonance Imaging; Image Processing, Computer-Assisted; Infarction, Middle Cerebral Artery; Male; Rats; Rats, Sprague-Dawley; Reperfusion; Software; Tetrazolium Salts; Time Factors | 2009 |
Enhanced cerebrovascular expression of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 via the MEK/ERK pathway during cerebral ischemia in the rat.
Topics: Actins; Animals; Astrocytes; Brain Infarction; Butadienes; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Infarction, Middle Cerebral Artery; Male; MAP Kinase Kinase Kinases; Matrix Metalloproteinase 1; Matrix Metalloproteinase 9; Microvessels; Muscle, Smooth; Neurologic Examination; Nitriles; Rats; Rats, Wistar; Signal Transduction; Tetrazolium Salts; Tissue Inhibitor of Metalloproteinase-1 | 2009 |
GIF-0173 protects against cerebral infarction through DP1 receptor activation.
Topics: Animals; Brain Infarction; Calcium; Cell Death; Cells, Cultured; Cerebral Cortex; Cerebrovascular Circulation; Dantrolene; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamic Acid; Hydantoins; Infarction, Middle Cerebral Artery; Intracellular Fluid; Lactones; Laser-Doppler Flowmetry; Male; N-Methylaspartate; Neurons; Neuroprotective Agents; Platelet Aggregation Inhibitors; Prostaglandin D2; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Immunologic; Receptors, Prostaglandin; Sesquiterpenes; Severity of Illness Index; Tetrazolium Salts | 2009 |
Pyruvate protects against experimental stroke via an anti-inflammatory mechanism.
Topics: Animals; Body Weight; Cell Count; Disease Models, Animal; Ectodysplasins; Encephalitis; Infarction, Middle Cerebral Artery; Lactic Acid; Lipopolysaccharides; Male; Matrix Metalloproteinase 9; Microglia; Motor Activity; Nervous System Diseases; Neutrophil Infiltration; NF-kappaB-Inducing Kinase; Protein Serine-Threonine Kinases; Psychomotor Performance; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Tetrazolium Salts | 2009 |
Uridine 5'-triphosphate (UTP) protects against cerebral ischemia reperfusion injury in rats.
Topics: Animals; Brain; Cell Death; Cerebrovascular Disorders; Dose-Response Relationship, Drug; Infarction, Middle Cerebral Artery; Magnetic Resonance Imaging; Male; Microscopy, Electron; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Severity of Illness Index; Tetrazolium Salts; Uridine Triphosphate; Water | 2009 |
Induction profile of MANF/ARMET by cerebral ischemia and its implication for neuron protection.
Topics: Animals; Blotting, Western; Brain Ischemia; Cells, Cultured; Coloring Agents; Endoplasmic Reticulum; Female; Fluorescent Antibody Technique; Immunohistochemistry; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Magnetic Resonance Imaging; Male; Nerve Growth Factors; Neurons; Pregnancy; Proteins; Rats; Rats, Sprague-Dawley; Tetrazolium Salts | 2010 |
Correlation of locomotor activity and brain infarction in rats with transient focal ischemia.
Topics: Animals; Brain; Brain Infarction; Disease Models, Animal; Functional Laterality; Infarction, Middle Cerebral Artery; Infrared Rays; Ischemic Attack, Transient; Male; Motor Activity; Rats; Stereotyped Behavior; Tetrazolium Salts; Time Factors | 2010 |
Green tea polyphenol (-)-epigallocatechin gallate reduces matrix metalloproteinase-9 activity following transient focal cerebral ischemia.
Topics: Animals; Catechin; Flavonoids; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Male; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Phenols; Polyphenols; Tea; Tetrazolium Salts; Up-Regulation | 2010 |
TTC staining of damaged brain areas after MCA occlusion in the rat does not constrict quantitative gene and protein analyses.
Topics: Animals; Brain; Coloring Agents; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation; Histological Techniques; Infarction, Middle Cerebral Artery; Interleukin-1beta; Male; Molecular Probe Techniques; Proteins; Rats; Rats, Wistar; RNA; Stroke; Tetrazolium Salts; Tumor Necrosis Factor-alpha | 2010 |
Glucosamine exerts a neuroprotective effect via suppression of inflammation in rat brain ischemia/reperfusion injury.
Topics: Animals; Brain Infarction; Cell Line, Transformed; Cell Survival; Chromatin Immunoprecipitation; Disease Models, Animal; Electrophoretic Mobility Shift Assay; Encephalitis; Enzyme Inhibitors; Gene Expression Regulation; Glucosamine; Infarction, Middle Cerebral Artery; Lipopolysaccharides; Male; Mice; Microglia; Neuroprotective Agents; NF-kappa B; Rats; RNA, Messenger; Severity of Illness Index; Tetrazolium Salts; Transfection | 2010 |
Lentivirus-mediated transfer of MMP-9 shRNA provides neuroprotection following focal ischemic brain injury in rats.
Topics: Analysis of Variance; Animals; Blood-Brain Barrier; Cell Line, Transformed; Cells, Cultured; Disease Models, Animal; Evans Blue; Gene Expression Regulation; Gene Transfer Techniques; Infarction, Middle Cerebral Artery; Lentivirus; Male; Matrix Metalloproteinase 9; Rats; Rats, Sprague-Dawley; RNA, Messenger; RNA, Small Interfering; Single-Blind Method; Tetrazolium Salts; Trauma Severity Indices | 2011 |
Extracellular spermine exacerbates ischemic neuronal injury through sensitization of ASIC1a channels to extracellular acidosis.
Topics: Acid Sensing Ion Channels; Acidosis; Amino Acid Transport System y+; Animals; Biophysics; Brain Injuries; Calcium; Cells, Cultured; CHO Cells; Cricetinae; Cricetulus; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Electric Stimulation; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Extracellular Fluid; GABA Antagonists; Glucose; Hippocampus; Hydrogen-Ion Concentration; Hypoxia; Infarction, Middle Cerebral Artery; L-Lactate Dehydrogenase; Membrane Potentials; Mice; Mice, Knockout; Mutation; Nerve Tissue Proteins; Neurons; Oligonucleotides; Patch-Clamp Techniques; Picrotoxin; Putrescine; Sodium Channels; Spermine; Tetrazolium Salts; Time Factors; Transfection; Valine | 2011 |
Mouse model of middle cerebral artery occlusion.
Topics: Animals; Coloring Agents; Disease Models, Animal; Infarction, Middle Cerebral Artery; Mice; Middle Cerebral Artery; Tetrazolium Salts | 2011 |
Cerebroside-A provides potent neuroprotection after cerebral ischaemia through reducing glutamate release and Ca²⁺ influx of NMDA receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Brain Ischemia; Calcium; Cerebral Infarction; Cerebrosides; Charybdotoxin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glucose; Glutamic Acid; Hippocampus; Hypoxia; In Vitro Techniques; Infarction, Middle Cerebral Artery; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neuroprotective Agents; Neurotoxins; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Tetrazolium Salts; Valine | 2012 |
Hyperglycemia and hemorrhagic transformation of cerebral infarction: a macroscopic hemorrhagic transformation rat model.
Topics: Animals; Brain Infarction; Disease Models, Animal; Functional Laterality; Hemorrhagic Disorders; Hyperglycemia; Infarction, Middle Cerebral Artery; Male; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Statistics, Nonparametric; Tetrazolium Salts; Time Factors | 2011 |
Capsaicin pre-treatment provides neurovascular protection against neonatal hypoxic-ischemic brain injury in rats.
Topics: Analysis of Variance; Animals; Animals, Newborn; Brain Infarction; Capsaicin; Disease Models, Animal; Drug Administration Schedule; Gene Expression Regulation; Infarction, Middle Cerebral Artery; Middle Cerebral Artery; Neuroprotective Agents; Phosphopyruvate Hydratase; Rats; Tetrazolium Salts; Time Factors; TRPV Cation Channels; von Willebrand Factor | 2011 |
In vivo optical imaging of ischemic blood-brain barrier disruption.
Topics: Animals; Blood-Brain Barrier; Brain; Carbocyanines; Cattle; Cone-Beam Computed Tomography; Contrast Media; Disease Models, Animal; Fluorescence; Histocytochemistry; Humans; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Male; Mice; Mice, Inbred Strains; Microtomy; Molecular Imaging; Reperfusion Injury; Serum Albumin; Tetrazolium Salts | 2011 |
[Amides of creatine: perspectives of neuroprotection].
Topics: Amides; Animals; Brain Ischemia; Creatine; Female; gamma-Aminobutyric Acid; Glycine; Hemodynamics; Image Processing, Computer-Assisted; Infarction, Middle Cerebral Artery; Injections, Intraperitoneal; Injections, Intravenous; Ischemic Attack, Transient; Male; Microscopy; Microtomy; Models, Animal; Neuroprotective Agents; Phenylalanine; Rats; Rats, Wistar; Tetrazolium Salts; Tyrosine | 2011 |
Inhibition of sonic hedgehog signaling aggravates brain damage associated with the down-regulation of Gli1, Ptch1 and SOD1 expression in acute ischemic stroke.
Topics: Analysis of Variance; Animals; Brain Edema; Brain Infarction; Disease Models, Animal; Down-Regulation; Hedgehog Proteins; Infarction, Middle Cerebral Artery; Kruppel-Like Transcription Factors; Male; Neurologic Examination; Patched Receptors; Patched-1 Receptor; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; RNA, Messenger; Signal Transduction; Statistics, Nonparametric; Superoxide Dismutase; Superoxide Dismutase-1; Tetrazolium Salts; Veratrum Alkaloids; Zinc Finger Protein GLI1 | 2012 |
P2X7 receptor blockade prevents ATP excitotoxicity in neurons and reduces brain damage after ischemia.
Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Brain Injuries; Calcium; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Embryo, Mammalian; Excitatory Amino Acid Agonists; Fluoresceins; Glucose; Hypoxia; In Vitro Techniques; Infarction, Middle Cerebral Artery; Membrane Potentials; N-Methylaspartate; Neurologic Examination; Neurons; Organic Chemicals; Patch-Clamp Techniques; Phosphopyruvate Hydratase; Purinergic P2X Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2X7; Rosaniline Dyes; Tetrazolium Salts | 2012 |
Transmembrane protein 166 regulates autophagic and apoptotic activities following focal cerebral ischemic injury in rats.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Blood-Brain Barrier; Brain Edema; Disease Models, Animal; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Green Fluorescent Proteins; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Male; Membrane Proteins; Microtubule-Associated Proteins; Rats; Rats, Sprague-Dawley; RNA, Messenger; RNA, Small Interfering; Tetrazolium Salts; Time Factors; Transduction, Genetic | 2012 |
DL-3-n-Butylphthalide, an anti-oxidant agent, prevents neurological deficits and cerebral injury following stroke per functional analysis, magnetic resonance imaging and histological assessment.
Topics: Analysis of Variance; Animals; Antioxidants; Benzofurans; Brain Infarction; Brain Injuries; Cerebral Cortex; Disease Models, Animal; Infarction, Middle Cerebral Artery; Magnetic Resonance Imaging; Male; Nervous System Diseases; Neurologic Examination; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrazolium Salts | 2012 |
Albumin therapy enhances collateral perfusion after laser-induced middle cerebral artery branch occlusion: a laser speckle contrast flow study.
Topics: Algorithms; Animals; Arterial Occlusive Diseases; Cerebrovascular Circulation; Collateral Circulation; Coloring Agents; Humans; Image Processing, Computer-Assisted; Infarction, Middle Cerebral Artery; Laser-Doppler Flowmetry; Lasers; Magnetic Resonance Imaging; Male; Mice; Mice, Inbred BALB C; Middle Cerebral Artery; Neuroimaging; Serum Albumin; Tetrazolium Salts | 2012 |
RNA interference against repulsive guidance molecule A improves axon sprout and neural function recovery of rats after MCAO/reperfusion.
Topics: Adenoviridae; Analysis of Variance; Animals; Axons; Biotin; Brain Infarction; Cerebral Cortex; Dextrans; Disease Models, Animal; Extrapyramidal Tracts; Functional Laterality; Gait Disorders, Neurologic; Gene Expression Regulation; GPI-Linked Proteins; Green Fluorescent Proteins; Hippocampus; Humans; Infarction, Middle Cerebral Artery; Interleukin-1beta; Laser-Doppler Flowmetry; Male; Membrane Glycoproteins; Nerve Tissue Proteins; Pyramidal Tracts; Rats; Rats, Sprague-Dawley; Recovery of Function; Regional Blood Flow; Reperfusion; RNA Interference; RNA, Messenger; Stereotaxic Techniques; Tetrazolium Salts; Time Factors | 2012 |
A comparative study of neuroprotective effect of single and combined blockade of AT1 receptor and PARP-1 in focal cerebral ischaemia in rat.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Brain; Brain Edema; Coloring Agents; Drug Therapy, Combination; Infarction, Middle Cerebral Artery; Isoquinolines; Male; Neuroprotective Agents; Neuropsychological Tests; Oxidative Stress; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats, Sprague-Dawley; Reactive Oxygen Species; Tetrazoles; Tetrazolium Salts | 2014 |
Reduction of ischemic brain injury by administration of palmitoylethanolamide after transient middle cerebral artery occlusion in rats.
Topics: Amides; Animals; Astrocytes; Brain Injuries; Disease Models, Animal; Endocannabinoids; Ethanolamines; Glial Fibrillary Acidic Protein; Infarction, Middle Cerebral Artery; JNK Mitogen-Activated Protein Kinases; Male; Neuroprotective Agents; NF-kappaB-Inducing Kinase; Nitric Oxide Synthase Type II; Palmitic Acids; Protein Serine-Threonine Kinases; Rats; Rats, Wistar; Reperfusion Injury; Tetrazolium Salts; Tumor Necrosis Factor-alpha | 2012 |
Electroacupuncture promotes neurological functional recovery via the retinoic acid signaling pathway in rats following cerebral ischemia-reperfusion injury.
Topics: Animals; Brain; Brain Ischemia; Cell Proliferation; Disease Models, Animal; Electroacupuncture; Hippocampus; Infarction, Middle Cerebral Artery; Lateral Ventricles; Male; Neurogenesis; Rats; Rats, Sprague-Dawley; Recovery of Function; Reperfusion Injury; Signal Transduction; Stroke; Tetrazolium Salts; Tretinoin | 2013 |
Localizing coordinates of cerebral ischemic tissue without the need of staining in a rat model of focal cerebral infarct.
Topics: Animals; Disease Models, Animal; Infarction, Middle Cerebral Artery; Male; Rats; Rats, Sprague-Dawley; Staining and Labeling; Tetrazolium Salts | 2013 |
Characteristics of cerebral ischemia in major rat stroke models of middle cerebral artery ligation through craniectomy.
Topics: Animals; Blood Flow Velocity; Blood Pressure; Brain; Brain Edema; Cerebrovascular Circulation; Craniotomy; Disease Models, Animal; Functional Laterality; Infarction, Middle Cerebral Artery; Ligation; Male; Rats, Wistar; Reproducibility of Results; Severity of Illness Index; Tetrazolium Salts | 2014 |
Evidence that the EphA2 receptor exacerbates ischemic brain injury.
Topics: Animals; bcl-2-Associated X Protein; Blood-Brain Barrier; Brain Infarction; Brain Ischemia; Caspase 3; Cerebral Cortex; Ephrins; Gene Expression Regulation; Glucose; Infarction, Middle Cerebral Artery; Male; Matrix Metalloproteinase 9; Mice; Neurons; Receptor, EphA2; Reperfusion Injury; Signal Transduction; Tetrazolium Salts; Zonula Occludens-1 Protein | 2013 |
Restricted clinical efficacy of cyclosporin A on rat transient middle cerebral artery occlusion.
Topics: Animals; Arterial Occlusive Diseases; Blood-Brain Barrier; Brain; Coloring Agents; Cyclosporine; Dose-Response Relationship, Drug; Infarction, Middle Cerebral Artery; Injections, Intraperitoneal; Ischemic Attack, Transient; Male; Middle Cerebral Artery; Neuroprotective Agents; Rats; Rats, Wistar; Tetrazolium Salts | 2002 |
Adenovirus-mediated Bcl-X(L) expression using a neuron-specific synapsin-1 promoter protects against disseminated neuronal injury and brain infarction following focal cerebral ischemia in mice.
Topics: Adenoviridae; Animals; bcl-X Protein; Brain Infarction; Brain Ischemia; Cell Death; Cerebrovascular Circulation; Gene Expression Regulation, Viral; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Immunohistochemistry; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred C57BL; Nerve Degeneration; Promoter Regions, Genetic; Proto-Oncogene Proteins c-bcl-2; Synapsins; Tetrazolium Salts; Treatment Outcome | 2002 |
Post-treatment with a novel PARG inhibitor reduces infarct in cerebral ischemia in the rat.
Topics: Animals; Brain; Brain Ischemia; Cerebral Infarction; Coloring Agents; Diamide; Enzyme Inhibitors; Glycoside Hydrolases; Infarction, Middle Cerebral Artery; Male; Rats; Rats, Sprague-Dawley; Reperfusion; Tetrazolium Salts; Time Factors | 2003 |
Inhibition of apoptosis by hyperbaric oxygen in a rat focal cerebral ischemic model.
Topics: Animals; Apoptosis; Brain; Brain Ischemia; Caspases; Coloring Agents; Disease Models, Animal; DNA Fragmentation; Hyperbaric Oxygenation; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Male; Neuropsychological Tests; Oxygen; Random Allocation; Rats; Rats, Sprague-Dawley; Tetrazolium Salts | 2003 |
Administration of the p38 MAPK inhibitor SB203580 affords brain protection with a wide therapeutic window against focal ischemic insult.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Astrocytes; Blotting, Western; Brain; Brain Infarction; Cyclooxygenase 2; Cytokines; Disease Models, Animal; Gene Expression Regulation; Imidazoles; Immunohistochemistry; Infarction, Middle Cerebral Artery; Isoenzymes; Lectins; Male; Microglia; Mitogen-Activated Protein Kinase 14; Mitogen-Activated Protein Kinases; Neurologic Examination; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Prostaglandin-Endoperoxide Synthases; Pyridines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Time Factors | 2003 |
17beta-Estradiol extends ischemic thresholds and exerts neuroprotective effects in cerebral subcortex against transient focal cerebral ischemia in rats.
Topics: Animals; Cell Death; Cerebral Cortex; Cerebral Infarction; Disease Models, Animal; Estradiol; Female; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Neuroprotective Agents; Ovariectomy; Rats; Rats, Sprague-Dawley; Staining and Labeling; Tetrazolium Salts; Time Factors | 2003 |
Rifampicin attenuates brain damage in focal ischemia.
Topics: Animals; Brain Infarction; Brain Ischemia; Cell Count; Cell Survival; Dose-Response Relationship, Drug; Enzyme Inhibitors; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Laser-Doppler Flowmetry; Male; Mice; Mice, Inbred C57BL; Reperfusion; Reperfusion Injury; Rifampin; Tetrazolium Salts | 2004 |
The effects of citicoline and lamotrigine alone and in combination following permanent middle cerebral artery occlusion in rats.
Topics: Analysis of Variance; Animals; Anticonvulsants; Brain; Brain Ischemia; Cerebral Infarction; Cytidine Diphosphate Choline; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Therapy, Combination; Infarction, Middle Cerebral Artery; Lamotrigine; Male; Neurologic Examination; Random Allocation; Rats; Rats, Wistar; Statistics, Nonparametric; Tetrazolium Salts; Treatment Outcome; Triazines | 2004 |
FK506 reduces infarct volume due to permanent focal cerebral ischemia by maintaining BAD turnover and inhibiting cytochrome c release.
Topics: Analysis of Variance; Animals; bcl-Associated Death Protein; Blotting, Western; Brain Infarction; Carrier Proteins; Cytochromes c; Dose-Response Relationship, Drug; Immunohistochemistry; Immunosuppressive Agents; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred BALB C; Neocortex; Phosphorylation; Tacrolimus; Tetrazolium Salts; Time Factors | 2004 |
Neurotransmitter release in experimental stroke models: the role of glutamate-GABA interaction.
Topics: Action Potentials; Animals; Brain; D-Aspartic Acid; Disease Models, Animal; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Hypoxia; In Vitro Techniques; Infarction, Middle Cerebral Artery; Neural Pathways; Neurons; Stroke; Tetrazolium Salts; Tritium | 2004 |
Spermine reduces infarction and neurological deficit following a rat model of middle cerebral artery occlusion: a magnetic resonance imaging study.
Topics: Analysis of Variance; Animals; Behavior, Animal; Brain Chemistry; Brain Infarction; Brain Mapping; Disease Models, Animal; Hand Strength; Hemiplegia; Infarction, Middle Cerebral Artery; Magnetic Resonance Imaging; Male; Nervous System Diseases; Nitrates; Nitrites; Paresis; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Spermine; Tetrazolium Salts; Time Factors | 2004 |
An optimized triphenyltetrazolium chloride method for identification of cerebral infarcts.
Topics: Animals; Artifacts; Cerebral Infarction; Coloring Agents; Disease Models, Animal; Drug Stability; Infarction, Middle Cerebral Artery; Male; Nerve Fibers, Myelinated; Rats; Rats, Wistar; Reperfusion Injury; Reproducibility of Results; Telencephalon; Tetrazolium Salts | 2004 |
A therapeutic window for intravenous administration of autologous bone marrow after cerebral ischemia in adult rats.
Topics: Animals; Behavior, Animal; Bone Marrow Cells; Bone Marrow Transplantation; Brain Infarction; Brain Ischemia; Cell Count; Disease Models, Animal; Exercise Test; Glial Fibrillary Acidic Protein; Immunohistochemistry; Infarction, Middle Cerebral Artery; Injections, Intravenous; Male; Maze Learning; Motor Activity; Phosphopyruvate Hydratase; Rats; Rats, Sprague-Dawley; Recovery of Function; Staining and Labeling; Tetrazolium Salts; Time Factors; Transplantation, Autologous | 2004 |
Wide therapeutic time window for nimesulide neuroprotection in a model of transient focal cerebral ischemia in the rat.
Topics: Analysis of Variance; Animals; Behavior, Animal; Cerebral Infarction; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Immunoassay; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Male; Neurologic Examination; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Sulfonamides; Tetrazolium Salts; Time Factors; Treatment Outcome | 2004 |
Validation of a simple and inexpensive method for the quantitation of infarct in the rat brain.
Topics: Animals; Cerebral Infarction; Coloring Agents; Disease Models, Animal; Infarction, Middle Cerebral Artery; Male; Organ Size; Plethysmography; Rats; Rats, Wistar; Reproducibility of Results; Sensitivity and Specificity; Severity of Illness Index; Staining and Labeling; Tetrazolium Salts | 2004 |
Administration of N-acetylcysteine after focal cerebral ischemia protects brain and reduces inflammation in a rat model of experimental stroke.
Topics: Acetylcysteine; Animals; Brain Ischemia; Cerebrovascular Circulation; Cytokines; Disease Models, Animal; DNA Fragmentation; Dose-Response Relationship, Drug; Ectodysplasins; Free Radical Scavengers; Glial Fibrillary Acidic Protein; Glutathione; Immunohistochemistry; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Inflammation; Ischemic Attack, Transient; Male; Membrane Proteins; Neurologic Examination; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Time Factors | 2004 |
Neuroprotective effect of gamma-glutamylethylamide (theanine) on cerebral infarction in mice.
Topics: Analysis of Variance; Animals; Cerebral Infarction; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamates; Infarction, Middle Cerebral Artery; Male; Mice; Neuroprotective Agents; Tetrazolium Salts | 2004 |
A reproducible experimental model of focal cerebral ischemia in the neonatal rat.
Topics: Animals; Animals, Newborn; Apoptosis; Brain Ischemia; Carbon; Cerebral Infarction; Disease Models, Animal; Female; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Pregnancy; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Suture Techniques; Tetrazolium Salts; Vascular Surgical Procedures | 2004 |
Src family kinase-inhibitor PP2 reduces focal ischemic brain injury.
Topics: Animals; Brain; Brain Ischemia; Cerebral Infarction; Disease Models, Animal; Infarction, Middle Cerebral Artery; Magnetic Resonance Imaging; Male; Neuroprotective Agents; Pyrimidines; Rats; Rats, Sprague-Dawley; Recovery of Function; src-Family Kinases; Tetrazolium Salts; Treatment Outcome | 2004 |
Necrosis, apoptosis and hybrid death in the cortex and thalamus after barrel cortex ischemia in rats.
Topics: Amino Acid Chloromethyl Ketones; Analysis of Variance; Animals; Apoptosis; Autoradiography; Brain Ischemia; Caspase 3; Caspases; Cell Count; Cerebral Cortex; Functional Laterality; Infarction, Middle Cerebral Artery; Injections, Intraventricular; Microscopy, Electron; Necrosis; Neurons; Neuroprotective Agents; Rats; Rats, Wistar; Regional Blood Flow; Staining and Labeling; Tetrazolium Salts; Thalamus; Time Factors | 2004 |
Midkine and retinoic acid reduce cerebral infarction induced by middle cerebral artery ligation in rats.
Topics: Alitretinoin; Analysis of Variance; Animals; Blood Gas Analysis; Blood Pressure; Body Temperature; Cells, Cultured; Cerebral Cortex; Cerebral Infarction; Cytokines; Embryo, Mammalian; Infarction, Middle Cerebral Artery; Male; Midkine; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Tretinoin | 2004 |
Anandamide content is increased and CB1 cannabinoid receptor blockade is protective during transient, focal cerebral ischemia.
Topics: Animals; Arachidonic Acids; Benzofurans; Benzoxazines; Blood Pressure; Brain Chemistry; Brain Infarction; Chromatography, Liquid; Disease Models, Animal; Dose-Response Relationship, Drug; Endocannabinoids; Hemodynamics; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Male; Mass Spectrometry; Morpholines; Naphthalenes; Neurologic Examination; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Reperfusion Injury; Rimonabant; Tetrazolium Salts; Time Factors | 2004 |
Angiotensin receptor gene expression in candesartan mediated neuroprotection.
Topics: Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Body Weight; Brain Infarction; Functional Laterality; Gene Expression; Heart Rate; Infarction, Middle Cerebral Artery; Male; Neurologic Examination; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazoles; Tetrazolium Salts; Time Factors | 2004 |
Dynamic susceptibility contrast-enhanced perfusion MR imaging at 1.5 T predicts final infarct size in a rat stroke model.
Topics: Animals; Brain; Cerebral Infarction; Contrast Media; Disease Models, Animal; Disease Progression; Infarction, Middle Cerebral Artery; Magnetic Resonance Angiography; Magnetics; Male; Observer Variation; Predictive Value of Tests; Rats; Rats, Sprague-Dawley; Staining and Labeling; Stroke; Tetrazolium Salts; Time Factors | 2005 |
Cannabidiol prevents infarction via the non-CB1 cannabinoid receptor mechanism.
Topics: Analysis of Variance; Animals; Body Temperature; Brain Infarction; Cannabidiol; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Drug Interactions; Fever; Infarction, Middle Cerebral Artery; Male; Mice; Neuroprotective Agents; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; Tetrazolium Salts; Time Factors | 2004 |
Neuroprotective effect of geranylgeranylacetone, a noninvasive heat shock protein inducer, on cerebral infarction in rats.
Topics: Animals; Cerebral Infarction; Diterpenes; Dose-Response Relationship, Drug; Gene Expression Regulation; HSP70 Heat-Shock Proteins; Immunohistochemistry; Infarction, Middle Cerebral Artery; Male; Neurologic Examination; Neuroprotective Agents; Rats; Tetrazolium Salts; Time Factors | 2005 |
The neuroprotective effect of glial cell line-derived neurotrophic factor in fibrin glue against chronic focal cerebral ischemia in conscious rats.
Topics: Animals; Behavior, Animal; Brain; Brain Infarction; Brain Ischemia; Chronic Disease; Disease Models, Animal; Drug Therapy, Combination; Fibrin Tissue Adhesive; Glial Cell Line-Derived Neurotrophic Factor; Infarction, Middle Cerebral Artery; Male; Motor Activity; Nerve Growth Factors; Neuroprotective Agents; Psychomotor Performance; Rats; Rats, Long-Evans; Rotarod Performance Test; Tetrazolium Salts; Time Factors; Wakefulness | 2005 |
The acoustic startle reflex in Sprague-Dawley rats is altered by permanent middle cerebral artery occlusion.
Topics: Acoustic Stimulation; Analysis of Variance; Animals; Brain Infarction; Disease Models, Animal; Dose-Response Relationship, Radiation; Infarction, Middle Cerebral Artery; Male; Rats; Rats, Sprague-Dawley; Reflex, Acoustic; Reflex, Startle; Tetrazolium Salts | 2005 |
Temporary focal ischemia in the mouse: technical aspects and patterns of Fluoro-Jade evident neurodegeneration.
Topics: Animals; Biomarkers; Brain; Brain Injuries; Cell Death; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Fluoresceins; Fluorescent Dyes; Hippocampus; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Mice; Mice, Inbred C57BL; Nerve Degeneration; Neurons; Organic Chemicals; Staining and Labeling; Tetrazolium Salts; Time Factors | 2005 |
Ischemic preconditioning procedure induces behavioral deficits in the absence of brain injury?
Topics: Animals; Behavior, Animal; Brain Injuries; CD11b Antigen; Ferritins; Forelimb; Heat-Shock Proteins; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; HSP27 Heat-Shock Proteins; Immunohistochemistry; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Ischemic Preconditioning; Locomotion; Male; Mental Disorders; Neoplasm Proteins; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Staining and Labeling; Statistics, Nonparametric; Tetrazolium Salts; Time Factors | 2005 |
Involvement of gamma protein kinase C in estrogen-induced neuroprotection against focal brain ischemia through G protein-coupled estrogen receptor.
Topics: Animals; Blood Glucose; Blotting, Western; Body Temperature; Brain; Brain Infarction; Brain Ischemia; CHO Cells; Cricetinae; Cricetulus; Estradiol; Estrogens; Female; Immunohistochemistry; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Confocal; Neurologic Examination; Neuroprotective Agents; Protein Kinase C; Receptors, Estrogen; Receptors, G-Protein-Coupled; Sex Factors; Tetrazolium Salts | 2005 |
Minocycline inhibits oxidative stress and decreases in vitro and in vivo ischemic neuronal damage.
Topics: Animals; Antioxidants; Benzimidazoles; Benzoxazoles; Biphenyl Compounds; Brain Edema; Brain Infarction; Cell Death; Cell Survival; Cells, Cultured; Cerebral Cortex; Chromans; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Fluorescent Dyes; Glutamic Acid; Hydrazines; Infarction, Middle Cerebral Artery; Inhibitory Concentration 50; Ischemia; Lipid Peroxidation; Male; Mice; Minocycline; Neurons; Neuroprotective Agents; Oxidative Stress; Picrates; Quinolinium Compounds; Saponins; Tetrazolium Salts; Time Factors | 2005 |
Progesterone suppresses the inflammatory response and nitric oxide synthase-2 expression following cerebral ischemia.
Topics: Animals; Brain; Brain Ischemia; Disease Models, Animal; Infarction, Middle Cerebral Artery; Inflammation; Interleukin-1; Magnetic Resonance Imaging; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Progesterone; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2005 |
The AMPA-antagonist talampanel is neuroprotective in rodent models of focal cerebral ischemia.
Topics: Animals; Benzodiazepines; Brain Infarction; Brain Ischemia; Disease Models, Animal; Dose-Response Relationship, Drug; Infarction, Middle Cerebral Artery; Laser-Doppler Flowmetry; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Rose Bengal; Tetrazolium Salts; Time Factors | 2005 |
Cerebral ischemia induced apoptosis and necrosis in normal and diabetic rats.
Topics: Analysis of Variance; Animals; Apoptosis; Brain; Brain Ischemia; Caspase 3; Caspases; Cell Count; Diabetes Mellitus, Experimental; Disease Models, Animal; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Male; Necrosis; Rats; Rats, Wistar; Reperfusion; Tetrazolium Salts; Time Factors | 2005 |
Differences in ischemic lesion evolution in different rat strains using diffusion and perfusion imaging.
Topics: Animals; Brain Ischemia; Cerebrovascular Circulation; Coloring Agents; Diffusion; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Infarction, Middle Cerebral Artery; Ischemia; Magnetic Resonance Angiography; Male; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; Species Specificity; Tetrazolium Salts; Time Factors | 2005 |
The pre-ischaemic neuroprotective effects of N1-dansyl-spermine in a transient focal cerebral ischaemia model in mice.
Topics: Animals; Brain; Brain Edema; Dansyl Compounds; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Male; Mice; Motor Activity; Neuroprotective Agents; Rotarod Performance Test; Spermine; Tetrazolium Salts; Time Factors | 2005 |
Social interaction improves experimental stroke outcome.
Topics: Animals; Behavior, Animal; Brain Ischemia; C-Reactive Protein; Cerebral Infarction; Cohort Studies; Coloring Agents; Corticosterone; Disease Models, Animal; Female; Infarction, Middle Cerebral Artery; Inflammation; Interpersonal Relations; Ischemia; Male; Mice; Mice, Inbred C57BL; Stroke; Stroke Rehabilitation; Tetrazolium Salts; Time Factors; Treatment Outcome | 2005 |
Inhibition of the cerebral ischemic injury by ethyl pyruvate with a wide therapeutic window.
Topics: Animals; Brain; Brain Injuries; Brain Ischemia; Coloring Agents; Cytokines; Dose-Response Relationship, Drug; Immunoblotting; Immunohistochemistry; Infarction, Middle Cerebral Artery; Inflammation; Ischemia; Lipopolysaccharides; Male; Microglia; Neuroprotective Agents; Neuropsychological Tests; Nitric Oxide; Pyruvates; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Sepsis; Tetrazolium Salts; Time Factors | 2005 |
Phosphodiesterase 5 inhibitor, zaprinast, selectively increases cerebral blood flow in the ischemic penumbra in the rat brain.
Topics: Analysis of Variance; Animals; Blood Circulation Time; Blood Pressure; Brain Ischemia; Cerebrovascular Circulation; Cyclic GMP; Disease Models, Animal; Functional Laterality; Immunoenzyme Techniques; Infarction, Middle Cerebral Artery; Laser-Doppler Flowmetry; Male; Nitric Oxide Donors; Penicillamine; Phosphodiesterase Inhibitors; Purinones; Rats; Rats, Wistar; Regional Blood Flow; Tetrazolium Salts; Time Factors | 2005 |
Alteration of collapsin response mediator protein-2 expression in focal ischemic rat brain.
Topics: Amino Acid Sequence; Animals; Brain Ischemia; Carotid Arteries; Coloring Agents; Electrophoresis, Gel, Two-Dimensional; Immunoblotting; Infarction, Middle Cerebral Artery; Intercellular Signaling Peptides and Proteins; Male; Middle Cerebral Artery; Molecular Sequence Data; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tetrazolium Salts; Up-Regulation | 2005 |
Relaxin-induced reduction of infarct size in male rats receiving MCAO is dependent on nitric oxide synthesis and not estrogenic mechanisms.
Topics: Analysis of Variance; Animals; Brain Infarction; Drug Interactions; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Fulvestrant; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; Nitric Oxide; Ornithine; Rats; Relaxin; Tetrazolium Salts | 2006 |
Chaperonin GroEL and its mutant D87K protect from ischemia in vivo and in vitro.
Topics: Analysis of Variance; Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Blotting, Western; Brain; Cell Aggregation; Cell Count; Cell Death; Cells, Cultured; Chaperonin 60; Cricetinae; Cricetulus; Fluorescent Antibody Technique; Glial Fibrillary Acidic Protein; Glucose; Hot Temperature; Hypoxia; In Vitro Techniques; Infarction, Middle Cerebral Artery; Ischemia; Lysine; Mice; Microtubule-Associated Proteins; Mutation; Neurons; Tetrazolium Salts; Time Factors; Transfection | 2006 |
Differential expression patterns of gangliosides in the ischemic cerebral cortex produced by middle cerebral artery occlusion.
Topics: Animals; Brain Ischemia; Cerebral Cortex; Chromatography, Thin Layer; G(M1) Ganglioside; G(M3) Ganglioside; In Situ Hybridization; Infarction, Middle Cerebral Artery; Microscopy, Fluorescence; Middle Cerebral Artery; Rats; Rats, Wistar; Sialyltransferases; Tetrazolium Salts | 2005 |
Geranylgeranylacetone, a noninvasive heat shock protein inducer, induces protein kinase C and leads to neuroprotection against cerebral infarction in rats.
Topics: Alkaloids; Animals; Benzophenanthridines; Blotting, Western; Cerebral Infarction; Disease Models, Animal; Diterpenes; Drug Interactions; Enzyme Inhibitors; Gene Expression; HSP70 Heat-Shock Proteins; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; Phenanthridines; Protein Kinase C; Rats; Rats, Wistar; Tetrazolium Salts; Time Factors | 2006 |
Modification of the method of thread manufacture improves stroke induction rate and reduces mortality after thread-occlusion of the middle cerebral artery in young or aged rats.
Topics: Aging; Animals; Brain Infarction; Cerebrovascular Circulation; Constriction, Pathologic; Disease Models, Animal; Infarction, Middle Cerebral Artery; Laser-Doppler Flowmetry; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Regional Blood Flow; Silicon Compounds; Tetrazolium Salts | 2006 |
Extended therapeutic time window after focal cerebral ischemia by non-competitive inhibition of AMPA receptors.
Topics: Animals; Benzodiazepines; Brain Infarction; Dioxoles; Disease Models, Animal; Dose-Response Relationship, Drug; Infarction, Middle Cerebral Artery; Male; Mice; Rats; Receptors, AMPA; Tetrazolium Salts; Time Factors | 2006 |
Neurovascular and neuronal protection by E64d after focal cerebral ischemia in rats.
Topics: Analysis of Variance; Animals; Apoptosis; Brain Edema; Brain Infarction; Brain Ischemia; Calpain; Caspase 3; Caspases; Cathepsins; Endothelium, Vascular; Functional Laterality; Gene Expression; Immunohistochemistry; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Leucine; Male; Neurologic Examination; Neurons; Neuroprotective Agents; Phosphopyruvate Hydratase; Rats; Rats, Sprague-Dawley; Tetrazolium Salts | 2006 |
Comparison of inhibitory action of candesartan and enalapril on brain ischemia through inhibition of oxidative stress.
Topics: Analysis of Variance; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Brain; Brain Ischemia; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Enalapril; Histocompatibility Antigens; Immunohistochemistry; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Superoxides; Tetrazoles; Tetrazolium Salts | 2006 |
Use of TTC staining for the evaluation of tissue injury in the early phases of reperfusion after focal cerebral ischemia in rats.
Topics: Animals; Brain Ischemia; Coloring Agents; Evans Blue; Fluoresceins; Fluorescent Dyes; Indoles; Infarction, Middle Cerebral Artery; Male; Microscopy, Electron; Middle Cerebral Artery; Myocardium; Organic Chemicals; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tetrazolium Salts | 2006 |
Olanzapine attenuates brain damage after focal cerebral ischemia in vivo.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Brain; Brain Ischemia; Cerebral Infarction; Cerebrovascular Circulation; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Infarction, Middle Cerebral Artery; Laser-Doppler Flowmetry; Male; Mice; Nerve Degeneration; Neuroprotective Agents; Olanzapine; Tetrazolium Salts; Treatment Outcome | 2006 |
Postischemic augmentation of conducted dilation in cerebral arterioles.
Topics: Adenosine; Adenosine Triphosphate; Animals; Arterioles; Brain Ischemia; Cerebral Arteries; Cerebrovascular Circulation; Disease Models, Animal; Infarction, Middle Cerebral Artery; Male; Microcirculation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tetrazolium Salts; Vasoconstriction; Vasodilation; Vasomotor System | 2007 |
Comparison between coated vs. uncoated suture middle cerebral artery occlusion in the rat as assessed by perfusion/diffusion weighted imaging.
Topics: Animals; Cerebrovascular Circulation; Diffusion; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Functional Laterality; Infarction, Middle Cerebral Artery; Male; Perfusion; Rats; Rats, Sprague-Dawley; Silicon; Surface Properties; Sutures; Tetrazolium Salts; Time Factors | 2007 |
Neuroprotective effect of taurine against focal cerebral ischemia in rats possibly mediated by activation of both GABAA and glycine receptors.
Topics: Animals; Blotting, Western; Body Water; Brain Chemistry; Caspase 3; Dose-Response Relationship, Drug; GABA Antagonists; Immunohistochemistry; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Magnetic Resonance Imaging; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Glycine; Taurine; Tetrazolium Salts; Thermogravimetry | 2007 |
Delayed treatment with cannabidiol has a cerebroprotective action via a cannabinoid receptor-independent myeloperoxidase-inhibiting mechanism.
Topics: Animals; Behavior, Animal; Cannabidiol; Cerebrovascular Circulation; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Functional Laterality; Glutamic Acid; Infarction, Middle Cerebral Artery; Male; Mice; Motor Activity; Neuroprotective Agents; Perfusion; Peroxidase; Piperidines; Pyrazoles; Receptors, Cannabinoid; Rimonabant; Tetrazolium Salts; Time Factors | 2007 |
Therapeutic benefits by human mesenchymal stem cells (hMSCs) and Ang-1 gene-modified hMSCs after cerebral ischemia.
Topics: Adenoviridae; Angiopoietin-1; Animals; Brain Ischemia; Coloring Agents; Exercise Test; Galactosides; Genetic Therapy; Humans; Image Processing, Computer-Assisted; Immunohistochemistry; Indoles; Infarction, Middle Cerebral Artery; Injections, Intravenous; Magnetic Resonance Imaging; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Neovascularization, Physiologic; Rats; Tetrazolium Salts | 2008 |
Intraluminal suture occlusion and ligation of the distal branch of internal carotid artery: an improved rat model of focal cerebral ischemia-reperfusion.
Topics: Animals; Brain Ischemia; Carotid Artery, Internal; Cerebral Infarction; Disease Models, Animal; Evaluation Studies as Topic; Infarction, Middle Cerebral Artery; Ligation; Male; Neurologic Examination; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion; Statistics, Nonparametric; Suture Techniques; Tetrazolium Salts; Time Factors | 2008 |
Inducible nitric oxide synthase and estradiol exhibit complementary neuroprotective roles after ischemic brain injury.
Topics: Analysis of Variance; Animals; Brain; Disease Models, Animal; Down-Regulation; Estradiol; Estrogens; Female; Infarction, Middle Cerebral Artery; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide Synthase Type II; Ovariectomy; Tetrazolium Salts | 2008 |
DCPIB, a specific inhibitor of volume regulated anion channels (VRACs), reduces infarct size in MCAo and the release of glutamate in the ischemic cortical penumbra.
Topics: Animals; Aspartic Acid; Brain Infarction; Chromatography, High Pressure Liquid; Cyclopentanes; Dialysis; Disease Models, Animal; Drug Administration Routes; Fluorenes; Glutamic Acid; Indans; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Tetrazolium Salts | 2008 |
Detrimental effects of tropisetron on permanent ischemic stroke in the rat.
Topics: Animals; Brain Infarction; Disease Models, Animal; Dose-Response Relationship, Drug; Indoles; Infarction, Middle Cerebral Artery; Male; Random Allocation; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Severity of Illness Index; Tetrazolium Salts; Tropisetron | 2008 |
Chronic cerebral hypoperfusion protects against acute focal ischemia, improves motor function, and results in vascular remodeling.
Topics: Analysis of Variance; Animals; Blood Vessels; Brain; Infarction, Middle Cerebral Artery; Ischemic Preconditioning; Male; Motor Activity; Neurologic Examination; Rats; Rats, Sprague-Dawley; Reperfusion; Tetrazolium Salts; Time Factors | 2008 |
The neuroprotective effect of olanzapine.
Topics: Analysis of Variance; Animals; Benzodiazepines; Brain Infarction; Dose-Response Relationship, Drug; Drug Evaluation; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Olanzapine; Tetrazolium Salts | 2008 |
Reduction of ischemic stroke in rat brain by alpha melanocyte stimulating hormone.
Topics: alpha-MSH; Animals; Brain; Brain Ischemia; Infarction, Middle Cerebral Artery; Magnetic Resonance Imaging; Male; Rats; Rats, Wistar; Stroke; Tetrazolium Salts | 2008 |
Intracerebral transplantation of human adipose tissue stromal cells after middle cerebral artery occlusion in rats.
Topics: Adipose Tissue; Animals; Cell Differentiation; Cell Movement; Cells, Cultured; Disease Models, Animal; Humans; Infarction, Middle Cerebral Artery; Lateral Ventricles; Male; Movement Disorders; Rats; Rats, Wistar; Recovery of Function; Stromal Cells; Tetrazolium Salts; Time Factors | 2008 |
Postconditioning with isoflurane reduced ischemia-induced brain injury in rats.
Topics: Anesthetics, Inhalation; Animals; Brain; Decanoic Acids; Dose-Response Relationship, Drug; Glyburide; Hydroxy Acids; Hypoxia-Ischemia, Brain; Infarction, Middle Cerebral Artery; Isoflurane; Male; Middle Cerebral Artery; Neuroprotective Agents; Organ Culture Techniques; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tetrazolium Salts | 2008 |
Spontaneous hyperthermia and its mechanism in the intraluminal suture middle cerebral artery occlusion model of rats.
Topics: Analysis of Variance; Animals; Arterial Occlusive Diseases; Body Temperature; Brain Ischemia; Carotid Artery, Internal; Cerebrovascular Circulation; Coloring Agents; Disease Models, Animal; Fever; Hypothalamus; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Magnetic Resonance Imaging; Male; Middle Cerebral Artery; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion; Stroke; Suture Techniques; Tetrazolium Salts; Time Factors | 1999 |
Evaluation of an optimal temperature for brain storage in delayed 2, 3,5-triphenyltetrazolium chloride staining.
Topics: Animals; Brain Ischemia; Coloring Agents; Infarction, Middle Cerebral Artery; Intracranial Embolism; Male; Rats; Rats, Sprague-Dawley; Specimen Handling; Staining and Labeling; Stroke; Temperature; Tetrazolium Salts | 2000 |
Systemic administration of a water-soluble hexasulfonated C(60) (FC(4)S) reduces cerebral ischemia-induced infarct volume in gerbils.
Topics: Animals; Brain Ischemia; Carbon; Free Radical Scavengers; Fullerenes; Gerbillinae; Infarction, Middle Cerebral Artery; Male; Motor Activity; Neuroprotective Agents; Oxidative Stress; Solubility; Tetrazolium Salts; Water | 2001 |
Effects of recombinant tissue plasminogen activator after intraluminal thread occlusion in mice: role of hemodynamic alterations.
Topics: Animals; Antipyrine; Autoradiography; Brain Edema; Brain Ischemia; Cerebrovascular Circulation; Coloring Agents; Dose-Response Relationship, Drug; Hemodynamics; Heparin; Infarction, Middle Cerebral Artery; Laser-Doppler Flowmetry; Male; Mice; Mice, Inbred C57BL; Recombinant Proteins; Tetrazolium Salts; Tissue Plasminogen Activator | 2001 |