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tripelennamine and Chemical Dependence

tripelennamine has been researched along with Chemical Dependence in 59 studies

Tripelennamine: A histamine H1 antagonist with low sedative action but frequent gastrointestinal irritation. It is used to treat ASTHMA; HAY FEVER; URTICARIA; and RHINITIS; and also in veterinary applications. Tripelennamine is administered by various routes, including topically.

Research Excerpts

ExcerptRelevanceReference
"This paper describes patterns of drug use such as choice of drug, other substances abused, and route of administration in 174 women who reported methamphetamine, cocaine, heroin, or "Ts and blues" abuse during pregnancy."3.68Patterns of multiple substance abuse during pregnancy: implications for mother and fetus. ( Gilstrap, LD; Johnston, WL; Little, BB; Snell, LM, 1990)
" Following her routine intravenous (IV) injection of solubilized pentazocine and tripelennamine tablets ("Ts and Blues"), the patient developed severe hypertension, a finding not characteristic of either drug alone or of the combination."3.67An acute hypertensive response after intravenous use of a new pentazocine formulation. ( Barrett, SM; Reinhart, S, 1985)
"Two drug addicts who practiced subcutaneous injection of crushed tripelennamine and pentazocine tablets, a practice known as "skin-popping," developed nephrotic syndrome and demonstrated amyloidosis on renal biopsy."3.66Renal amyloidosis and subcutaneous drug abuse. ( Lewis, EJ; Meador, KH; Sharon, Z, 1979)
"Tripelennamine (1-10 mg/kg) was administered SC 45 min."1.29Effects of trepelennamine on brain monoamine turnover in morphine dependent and abstinent mice. ( Cuellar, B; Leza, JC; Lizasoain, I; Lorenzo, P; San-Martin-Clark, O, 1996)
"Acute bacterial endocarditis, a fulminating disorder most often caused by Staphylococcus aureus, is uncommon in pregnancy."1.27Acute bacterial endocarditis in pregnancy. A report of three cases. ( Faro, S; Pastorek, JG; Plauche, WC, 1983)
" These results are similar to previous results obtained with tripelennamine and pentazocine suggesting that nalbuphine may have abuse potential if combined with tripelennamine."1.27Effects of nalbuphine alone and in combination with tripelennamine on rewarding brain stimulation thresholds in the rat. ( Kornetsky, C; Unterwald, EM, 1986)
" Dose-response curves (derived from the results of using the tablets as well as pure powders) showed that tripelennamine was responsible for the inhibitory activity, which was partially antagonized by pentazocine."1.27Selective survival in pentazocine and tripelennamine of Pseudomonas aeruginosa serotype O11 from drug addicts. ( Botsford, KB; Kabins, SA; Nathan, CR; Weinstein, RA, 1985)
"aeruginosa arthritis in intravenous drug abusers are discussed."1.26Pyogenic infections of the pubic symphysis. ( Jones, E; Kallick, C; Lorenz, M; Sequeira, W; Siegel, ME, 1982)
"In six, the major presentation was seizures."1.26Central nervous system complications of addiction to "T's and Blues". ( Banks, G; Caplan, LR; Thomas, C, 1982)
"Interviews were conducted with eight drug abusers at the Cook County Hospital Emergency Department who had used pentazocine (Talwin) and tripelennamine (Pyribenzamine) in combination--also known as "T's and Blues."1.26Pentazocine (Talwin) and tripelennamine (Pyribenzamine): a new drug abuse combination or just a revival? ( Stillie, GD; Wadley, C, 1980)
"A 38-year-old male drug abuser had multiple emboli in the retinal circulation of the posterior pole of both eyes."1.26Talc emboli and retinal neovascularization in a drug abuser. ( Goldberg, MF; Jampol, LM; Kresca, LJ, 1979)
"A current practice among drug abusers in certain Midwestern and Eastern cities is the intravenous injection of aqueous mixtures prepared from tablets of pentazocine and tripelennamine."1.26Abuse and pulmonary complications of injecting pentazocine and tripelennamine tablets. ( Butch, AJ; Hanenson, IB; Nelson, ED; Sigell, LT; Yokel, RA, 1979)

Research

Studies (59)

TimeframeStudies, this research(%)All Research%
pre-199056 (94.92)18.7374
1990's3 (5.08)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
O'DRISCOLL, WG1
LINDLEY, GR1
REVITCH, E1
WEISS, G1
ZELICKSON, AS1
ZELLER, HC1
WENDT, VE1
PURO, HE2
SHAPIRO, J1
MATHEWS, W1
WOLF, PL2
Shook, JE1
Kallman, MJ1
Martin, BR1
Dewey, WL1
Gorodetzky, CW1
Cone, EJ1
Johnson, RE2
Risner, ME1
Su, TP1
Yeh, SY1
Jasinski, DR1
Boren, JJ1
Henningfield, JE1
Lange, WR1
Lukas, SE1
Miskew, DB1
Lorenz, MA1
Pearson, RL1
Pankovich, AM1
Chasnoff, IJ2
Burns, WJ1
Schnoll, SH3
Levin, MH1
Weinstein, RA2
Nathan, C1
Selander, RK1
Ochman, H1
Kabins, SA2
Poklis, A5
Pastorek, JG1
Plauche, WC1
Faro, S1
True, WR1
Pevnick, JS1
Schaffer, MI1
Lin, RL1
Wu Chen, NB1
Trojan, C1
Teas, S1
Stein, RJ1
Brust, JC1
Itkonen, J1
Schnoll, S1
Daghestani, A1
Glassroth, J2
Carlson, C2
Case, ME1
Ridenour, GC1
Heaney, RM1
Gotlieb, N1
Mackell, MA1
Sequeira, W1
Jones, E1
Siegel, ME1
Lorenz, M1
Kallick, C1
Levitsky, S1
Mammana, RB1
Silverman, NA1
Weber, F1
Hiro, S1
Wright, RN1
Caplan, LR1
Thomas, C1
Banks, G1
Lahmeyer, HW4
Steingold, RG2
Wadley, C1
Stillie, GD1
Whyatt, PL1
Showalter, CV1
Reid, RW1
Gerbeck, CM1
San-Martin-Clark, O1
Cuellar, B1
Leza, JC1
Lizasoain, I1
Lorenzo, P1
Kaistha, KK1
Tadrus, R1
Kresca, LJ1
Goldberg, MF1
Jampol, LM1
Butch, AJ1
Yokel, RA1
Sigell, LT1
Hanenson, IB1
Nelson, ED1
Meador, KH1
Sharon, Z1
Lewis, EJ1
Bailey, WJ1
Shovalter, CV1
Beardsley, PM1
Balster, RL1
Little, BB1
Snell, LM1
Gilstrap, LD1
Johnston, WL1
Fuchs, V1
Coper, H1
Craig, RJ2
Mack, RB1
von Almen, WF1
Miller, JM1
Reed, DA1
Unterwald, EM1
Kornetsky, C2
May, DC1
Helderman, JH1
Eigenbrodt, EH1
Silva, FG1
Shekar, R1
Rice, TW1
Zierdt, CH1
Kallick, CA1
Botsford, KB1
Nathan, CR1
Woods, KF1
Hanna, BJ1
Reinhart, S1
Barrett, SM1
Senay, EC1
Jackson, C1
Hart, A1
Robinson, MD1
Szwed, JJ1
Burton, JF1
Zawadzki, S1
Wetherell, HR1
Moy, TW1
Skirgaudas, J1
Vazquez, J1

Trials

1 trial available for tripelennamine and Chemical Dependence

ArticleYear
Progress report from the NIDA Addiction Research Center (preclinical laboratory), Lexington, Kentucky.
    NIDA research monograph, 1984, Volume: 49

    Topics: Adult; Animals; Antipsychotic Agents; Cannabinoids; Clinical Trials as Topic; Cocaine; Dogs; Dose-Re

1984

Other Studies

58 other studies available for tripelennamine and Chemical Dependence

ArticleYear
Self-administration of tripelennamine by a narcotic addict.
    The New England journal of medicine, 1957, Aug-22, Volume: 257, Issue:8

    Topics: Humans; Narcotics; Self Administration; Self Care; Substance-Related Disorders; Tripelennamine

1957
Intravenous use of tripelennamine hydrochloride as a narcotic-like substitute.
    Diseases of the nervous system, 1959, Volume: 20, Issue:7

    Topics: Humans; Injections, Intravenous; Narcotics; Substance-Related Disorders; Tripelennamine

1959
PAREGORIC AND TRIPELENNAMINE ('BLUE VELVET') ADDICTION INCREASING, CLAIMS DETROIT PATHOLOGIST.
    JAMA, 1964, Apr-27, Volume: 188

    Topics: Chemical and Drug Induced Liver Injury; Endocarditis; Endocarditis, Bacterial; Hepatitis; Humans; Hy

1964
ANGIOTHROMBOTIC PULMONARY HYPERTENSION IN ADDICTS. "BLUE VELVET" ADDICTION.
    JAMA, 1964, May-25, Volume: 188

    Topics: Endocarditis; Endocarditis, Bacterial; Humans; Hypertension; Hypertension, Pulmonary; Injections, In

1964
Characterization of the interaction of pentazocine and tripelennamine: drug discrimination and mu-receptor binding assay.
    Pharmacology, biochemistry, and behavior, 1984, Volume: 21, Issue:6

    Topics: Animals; Discrimination, Psychological; Drug Interactions; Humans; Male; Mice; Mice, Inbred ICR; Mor

1984
Progress report from the NIDA Addiction Research Center, Baltimore, Maryland.
    NIDA research monograph, 1984, Volume: 49

    Topics: Anti-Anxiety Agents; Buprenorphine; Double-Blind Method; Dronabinol; Drug Synergism; Heroin Dependen

1984
Pseudomonas aeruginosa bone and joint infection in drug abusers.
    The Journal of bone and joint surgery. American volume, 1983, Volume: 65, Issue:6

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Bone Diseases; Female; Humans; Joint Diseases; Male; Middl

1983
Perinatal addiction: the effects of maternal narcotic and nonnarcotic substance abuse on the fetus and neonate.
    NIDA research monograph, 1984, Volume: 49

    Topics: Adult; Arousal; Birth Weight; Female; Heroin Dependence; Humans; Infant, Newborn; Infant, Newborn, D

1984
Association of infection caused by Pseudomonas aeruginosa serotype O11 with intravenous abuse of pentazocine mixed with tripelennamine.
    Journal of clinical microbiology, 1984, Volume: 20, Issue:4

    Topics: Drug Contamination; Humans; Injections, Intravenous; Pentazocine; Phenotype; Pseudomonas aeruginosa;

1984
Decline in abuse of pentazocine/tripelennamine (T's and Blues) associated with the addition of naloxone to pentazocine tablets.
    Drug and alcohol dependence, 1984, Volume: 14, Issue:2

    Topics: Drug Combinations; Euphoria; Heroin Dependence; Humans; Naloxone; Pentazocine; Substance-Related Dis

1984
Acute bacterial endocarditis in pregnancy. A report of three cases.
    The Journal of reproductive medicine, 1983, Volume: 28, Issue:9

    Topics: Acute Disease; Adult; Endocarditis, Bacterial; Female; Heroin; Humans; Injections, Intravenous; Pent

1983
Abuse of pentazocine combined with tripelennamine: an interaction of pharmacological and demographic characteristics.
    The International journal of the addictions, 1983, Volume: 18, Issue:8

    Topics: Adult; Anxiety; Demography; Euphoria; Humans; Male; Middle Aged; Narcotics; Pentazocine; Pilot Proje

1983
Spontaneous live birth with a maternal history of intravenous use of pentazocine and tripelennamine (T's and blues).
    Journal of forensic sciences, 1983, Volume: 28, Issue:2

    Topics: Adult; Chromatography, Gas; Female; Gas Chromatography-Mass Spectrometry; Humans; Infant, Newborn; I

1983
The nonimpact of opiate research on opiate abuse.
    Neurology, 1983, Volume: 33, Issue:10

    Topics: Dextropropoxyphene; Drug Tolerance; Heroin; Humans; Methadone; Narcotics; Pentazocine; Substance-Rel

1983
Accelerated development of pulmonary complications due to illicit intravenous use of pentazocine and tripelennamine.
    The American journal of medicine, 1984, Volume: 76, Issue:4

    Topics: Adult; Exercise Test; Female; Heroin; Humans; Lung; Male; Pentazocine; Respiration Disorders; Substa

1984
Talwin 50 reformulated to avert 'T's and blues' abuse.
    JAMA, 1983, Apr-01, Volume: 249, Issue:13

    Topics: Drug Combinations; Humans; Pentazocine; Substance-Related Disorders; Tripelennamine

1983
Abuse of pentazocine/tripelennamine combination. Ts and Blues in the city of St. Louis.
    Missouri medicine, 1983, Volume: 80, Issue:1

    Topics: Disease Outbreaks; Humans; Missouri; Pentazocine; Substance-Related Disorders; Tripelennamine

1983
Granulocytopenia after intravenous abuse of pentazocine and tripelennamine ("Ts and blues").
    Southern medical journal, 1983, Volume: 76, Issue:5

    Topics: Adult; Agranulocytosis; Humans; Injections, Intravenous; Male; Pentazocine; Substance-Related Disord

1983
Determination of pentazocine and tripelennamine in blood of T's and Blue addicts by gas-liquid chromatography with a nitrogen detector.
    Journal of chromatography, 1982, Jan-29, Volume: 235, Issue:2

    Topics: Chromatography, Gas; Humans; Pentazocine; Reference Values; Substance-Related Disorders; Tripelennam

1982
Pyogenic infections of the pubic symphysis.
    Annals of internal medicine, 1982, Volume: 96, Issue:5

    Topics: Adult; Arthritis, Infectious; Humans; Injections, Intravenous; Male; Pentazocine; Pubic Symphysis; R

1982
Acute endocarditis in drug addicts: surgical treatment for gram-negative sepsis.
    Circulation, 1982, Volume: 66, Issue:2 Pt 2

    Topics: Acute Disease; Adult; Aortic Valve; Endocarditis, Bacterial; Female; Heart Valve Prosthesis; Heroin

1982
The drug victim is too often the same: the fetus.
    JAMA, 1982, Jul-23, Volume: 248, Issue:4

    Topics: Female; Fetus; Humans; Infant, Newborn; Maternal-Fetal Exchange; Pentazocine; Pregnancy; Substance-R

1982
Central nervous system complications of addiction to "T's and Blues".
    Neurology, 1982, Volume: 32, Issue:6

    Topics: Adult; Bacterial Infections; Central Nervous System Diseases; Cerebrovascular Disorders; Female; For

1982
Pentazocine and tripelennamine: a drug abuse epidemic?
    The International journal of the addictions, 1980, Volume: 15, Issue:8

    Topics: Adolescent; Adult; Chicago; Female; Heroin Dependence; Humans; Male; Middle Aged; Pentazocine; Subst

1980
Pentazocine (Talwin) and tripelennamine (Pyribenzamine): a new drug abuse combination or just a revival?
    The International journal of the addictions, 1980, Volume: 15, Issue:8

    Topics: Adult; Chicago; Drug Therapy, Combination; Female; Humans; Male; Pentazocine; Substance-Related Diso

1980
Current trends in the abuse of pentazocine and tripelennamine: the metropolitan St. Louis experience.
    Journal of forensic sciences, 1980, Volume: 25, Issue:1

    Topics: Drug Combinations; Humans; Illicit Drugs; Missouri; Opioid-Related Disorders; Pentazocine; Substance

1980
Medical and psychiatric complications of pentazocine and tripelennamine abuse.
    The Journal of clinical psychiatry, 1980, Volume: 41, Issue:8

    Topics: Abscess; Cellulitis; Chicago; Depression; Drug Interactions; Humans; Male; Pentazocine; Psychoses, S

1980
T's and blues. Abuse of pentazocine and tripelennamine.
    JAMA, 1980, Sep-12, Volume: 244, Issue:11

    Topics: Humans; Injections, Intravenous; Methadone; Pentazocine; Substance Withdrawal Syndrome; Substance-Re

1980
Detection of pentazocine and tripelennamine in urine.
    Clinical chemistry, 1981, Volume: 27, Issue:1

    Topics: Chromatography, Gas; Chromatography, Thin Layer; Humans; Mass Spectrometry; Pentazocine; Substance-R

1981
Effects of trepelennamine on brain monoamine turnover in morphine dependent and abstinent mice.
    Psychopharmacology, 1996, Volume: 123, Issue:3

    Topics: Animals; Biogenic Monoamines; Brain; Dopamine; Male; Mice; Morphine; Substance-Related Disorders; Tr

1996
Thin-layer detection of pentazocine, tripelennamine, phencyclidine and propoxyphene alone or in combination with opiates in drug abuse urine screening programs.
    Journal of chromatography, 1978, Aug-01, Volume: 155, Issue:1

    Topics: Analgesics, Opioid; Chromatography, Thin Layer; Codeine; Dextropropoxyphene; Histamine H1 Antagonist

1978
Talc emboli and retinal neovascularization in a drug abuser.
    American journal of ophthalmology, 1979, Volume: 87, Issue:3

    Topics: Adult; Embolism; Heroin; Heroin Dependence; Humans; Injections, Intravenous; Male; Ophthalmoscopy; P

1979
Abuse and pulmonary complications of injecting pentazocine and tripelennamine tablets.
    Clinical toxicology, 1979, Volume: 14, Issue:3

    Topics: Adult; Humans; Injections, Intravenous; Lung Diseases; Male; Pentazocine; Substance-Related Disorder

1979
Renal amyloidosis and subcutaneous drug abuse.
    Annals of internal medicine, 1979, Volume: 91, Issue:4

    Topics: Adult; Amyloidosis; Female; Humans; Injections, Subcutaneous; Kidney; Kidney Diseases; Pentazocine;

1979
Nonmedical use of pentazocine.
    JAMA, 1979, Nov-30, Volume: 242, Issue:22

    Topics: Humans; Illicit Drugs; Pentazocine; Substance-Related Disorders; Tripelennamine

1979
Abuse of pentazocine and tripelennamine.
    JAMA, 1978, Apr-21, Volume: 239, Issue:16

    Topics: Diagnosis, Differential; Drug Synergism; Epilepsy; Humans; Pentazocine; Substance-Related Disorders;

1978
"T's and blues".
    JAMA, 1978, Jul-14, Volume: 240, Issue:2

    Topics: Humans; Legislation, Drug; Missouri; Pentazocine; Substance-Related Disorders; Tripelennamine

1978
The intravenous self-administration of antihistamines by rhesus monkeys.
    Drug and alcohol dependence, 1992, Volume: 30, Issue:2

    Topics: Animals; Benzhydryl Compounds; Chlorpheniramine; Cimetidine; Dose-Response Relationship, Drug; Hista

1992
Patterns of multiple substance abuse during pregnancy: implications for mother and fetus.
    Southern medical journal, 1990, Volume: 83, Issue:5

    Topics: Adolescent; Adult; Age Factors; Alcoholism; Cocaine; Female; Fetal Diseases; Heroin; Humans; Marijua

1990
The influence of antihistamine compounds on the oral intake of different addictive drugs.
    Drug and alcohol dependence, 1986, Volume: 17, Issue:4

    Topics: Amphetamine; Animals; Benzimidazoles; Diphenhydramine; Ethanol; Female; Histamine H1 Antagonists; Il

1986
Pentazocine--naloxone: another "addiction-proof" drug of abuse.
    The International journal of the addictions, 1987, Volume: 22, Issue:11

    Topics: Adult; Drug Combinations; Drug Interactions; Humans; Injections, Intravenous; Male; Naloxone; Pentaz

1987
My kingdom for a fix. "T's and blues"--was and is.
    North Carolina medical journal, 1987, Volume: 48, Issue:3

    Topics: Drug Interactions; Humans; Naloxone; Pentazocine; Substance-Related Disorders; Tripelennamine

1987
"Ts and Blues" in pregnancy.
    The Journal of reproductive medicine, 1986, Volume: 31, Issue:4

    Topics: Adult; Female; Fetal Death; Humans; Infant, Newborn; Infant, Small for Gestational Age; Obstetric La

1986
Abuse of pentazocine-naloxone combination.
    JAMA, 1986, Nov-14, Volume: 256, Issue:18

    Topics: Adult; Drug Combinations; Drug Interactions; Humans; Illicit Drugs; Injections, Intravenous; Male; N

1986
Effects of nalbuphine alone and in combination with tripelennamine on rewarding brain stimulation thresholds in the rat.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 25, Issue:3

    Topics: Animals; Drug Interactions; Male; Morphinans; Nalbuphine; Rats; Reinforcement, Psychology; Reward; S

1986
Pentazocine-naloxone: an "abuse proof" drug can be abused.
    Journal of clinical psychopharmacology, 1986, Volume: 6, Issue:6

    Topics: Adult; Drug Combinations; Humans; Male; Naloxone; Pentazocine; Substance-Related Disorders; Tripelen

1986
Chronic sclerosing glomerulopathy (heroin-associated nephropathy) in intravenous T's and Blues abusers.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1986, Volume: 8, Issue:6

    Topics: Adult; Biopsy; Glomerulonephritis; Glomerulosclerosis, Focal Segmental; Heroin Dependence; Humans; I

1986
Pentazocine and tripelennamine abuse: T's and Blues.
    Psychiatric medicine, 1985, Volume: 3, Issue:3

    Topics: Adult; Female; Humans; Infant, Newborn; Lung Diseases, Obstructive; Lung Volume Measurements; Male;

1985
Outbreak of endocarditis caused by Pseudomonas aeruginosa serotype O11 among pentazocine and tripelennamine abusers in Chicago.
    The Journal of infectious diseases, 1985, Volume: 151, Issue:2

    Topics: Chicago; Disease Outbreaks; Endocarditis, Bacterial; Humans; Pentazocine; Pseudomonas aeruginosa; Ps

1985
Selective survival in pentazocine and tripelennamine of Pseudomonas aeruginosa serotype O11 from drug addicts.
    The Journal of infectious diseases, 1985, Volume: 151, Issue:2

    Topics: Drug Interactions; Humans; Pentazocine; Phenotype; Pseudomonas aeruginosa; Pseudomonas Infections; S

1985
Brain-stimulation reward: a model for the neuronal bases for drug-induced euphoria.
    NIDA research monograph, 1985, Volume: 62

    Topics: Animals; Brain; Cocaine; Dextroamphetamine; Electric Stimulation; Euphoria; Humans; Models, Neurolog

1985
Brain stem mucormycosis in a narcotic addict with eventual recovery.
    The American journal of medicine, 1986, Volume: 80, Issue:1

    Topics: Adult; Amphotericin B; Brain Abscess; Brain Stem; Female; Humans; Hydrocephalus; Mucormycosis; Penta

1986
An acute hypertensive response after intravenous use of a new pentazocine formulation.
    Annals of emergency medicine, 1985, Volume: 14, Issue:6

    Topics: Adult; Clonidine; Female; Humans; Hypertension; Injections, Intravenous; Pentazocine; Substance-Rela

1985
Clinical experience with T's and B's.
    Drug and alcohol dependence, 1985, Volume: 14, Issue:3-4

    Topics: Adult; Bacterial Infections; Chicago; Cicatrix; Drug Interactions; Female; Humans; Injections, Intra

1985
Fatal intracranial hemorrhage associated with phenylpropanolamine, pentazocine, and tripelennamine overdose.
    The Journal of emergency medicine, 1985, Volume: 3, Issue:2

    Topics: Adult; Amphetamines; Cerebral Hemorrhage; Drug Synergism; Humans; Hypertension; Illicit Drugs; Male;

1985
Pulmonary angiothrombosis caused by "blue velvet" addiction.
    Annals of internal medicine, 1970, Volume: 73, Issue:5

    Topics: Adult; Biopsy; Dyspnea; Humans; Lung; Male; Pulmonary Artery; Pulmonary Fibrosis; Radiography, Thora

1970
Mainliners and blue velvet.
    Journal of forensic sciences, 1965, Volume: 10, Issue:4

    Topics: Adult; Autopsy; Death, Sudden; Foreign Bodies; Granuloma; Humans; Male; Pulmonary Edema; Pulmonary H

1965
Experimental production of human "blue velvet" and "red devil" lesions.
    JAMA, 1966, Sep-26, Volume: 197, Issue:13

    Topics: Animals; Camphor; Foreign Bodies; Humans; Injections, Intravenous; Meperidine; Microscopy, Polarizat

1966