tripelennamine and Arthritis, Rheumatoid studies

tripelennamine and Arthritis, Rheumatoid

Tripelennamine: A histamine H1 antagonist with low sedative action but frequent gastrointestinal irritation. It is used to treat ASTHMA; HAY FEVER; URTICARIA; and RHINITIS; and also in veterinary applications. Tripelennamine is administered by various routes, including topically.

Arthritis, Rheumatoid: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.

Research Excerpts

Excerpt	Relevance	Reference
"Histamine H1 receptors have been demonstrated on adherent rheumatoid synovial cells using biochemical and radioligand binding assays in vitro."	1.27	Histamine H1 receptors on adherent rheumatoid synovial cells in culture: demonstration by radioligand binding and inhibition of histamine-stimulated prostaglandin E production by histamine H1 antagonists. ( Taylor, DJ; Woolley, DE, 1987)

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (100.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

3 (100.00)

18.7374

1990's

0 (0.00)

18.2507

2000's

0 (0.00)

29.6817

2010's

0 (0.00)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Taylor, DJ	2
Woolley, DE	2
Saslaw, S	1
Klainer, AS	1

Studies

Taylor, DJ

Woolley, DE

Saslaw, S

Klainer, AS

Other Studies

3 other studies available for tripelennamine and Arthritis, Rheumatoid

Article	Year
Evidence for both histamine H1 and H2 receptors on human articular chondrocytes. Annals of the rheumatic diseases, 1987, Volume: 46, Issue:6 Topics: Arthritis, Rheumatoid; Cartilage, Articular; Cells, Cultured; Chlorpheniramine; Cyclic AMP; Histamin	1987
Histamine H1 receptors on adherent rheumatoid synovial cells in culture: demonstration by radioligand binding and inhibition of histamine-stimulated prostaglandin E production by histamine H1 antagonists. Annals of the rheumatic diseases, 1987, Volume: 46, Issue:6 Topics: Arthritis, Rheumatoid; Binding, Competitive; Cells, Cultured; Chlorpheniramine; Histamine; Histamine	1987
Rheumatoid syndrome during isoniazid therapy. The American review of respiratory disease, 1969, Volume: 100, Issue:2 Topics: Aminosalicylic Acids; Arthritis, Rheumatoid; C-Reactive Protein; Drug Hypersensitivity; Female; Huma	1969

Article

Year

Evidence for both histamine H1 and H2 receptors on human articular chondrocytes.

Annals of the rheumatic diseases, 1987, Volume: 46, Issue:6

Topics: Arthritis, Rheumatoid; Cartilage, Articular; Cells, Cultured; Chlorpheniramine; Cyclic AMP; Histamin

1987

Histamine H1 receptors on adherent rheumatoid synovial cells in culture: demonstration by radioligand binding and inhibition of histamine-stimulated prostaglandin E production by histamine H1 antagonists.

Annals of the rheumatic diseases, 1987, Volume: 46, Issue:6

Topics: Arthritis, Rheumatoid; Binding, Competitive; Cells, Cultured; Chlorpheniramine; Histamine; Histamine

1987

Rheumatoid syndrome during isoniazid therapy.

The American review of respiratory disease, 1969, Volume: 100, Issue:2

Topics: Aminosalicylic Acids; Arthritis, Rheumatoid; C-Reactive Protein; Drug Hypersensitivity; Female; Huma

1969