trioxsalen has been researched along with Viral Diseases in 2 studies
Trioxsalen: Pigmenting photosensitizing agent obtained from several plants, mainly Psoralea corylifolia. It is administered either topically or orally in conjunction with ultraviolet light in the treatment of vitiligo.
lactone : Any cyclic carboxylic ester containing a 1-oxacycloalkan-2-one structure, or an analogue having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.
antipsoriatic : A drug used to treat psoriasis.
trioxsalen : 7H-Furo[3,2-g]chromen-7-one in which positions 2, 5, and 9 are substituted by methyl groups. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered orally in conjunction with UV-A for phototherapy treatment of vitiligo. After photoactivation it creates interstrand cross-links in DNA, inhibiting DNA synthesis and cell division, and can lead to cell injury; recovery from the cell injury may be followed by increased melanisation of the epidermis.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 2 (100.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Margolis-Nunno, H | 1 |
Robinson, R | 1 |
Ben-Hur, E | 1 |
Horowitz, B | 1 |
Moroff, G | 1 |
Wagner, S | 1 |
Benade, L | 1 |
Dodd, RY | 1 |
2 other studies available for trioxsalen and Viral Diseases
Article | Year |
---|---|
Quencher-enhanced specificity of psoralen-photosensitized virus inactivation in platelet concentrates.
Topics: Antiviral Agents; Bacteriophage M13; Blood Platelets; Humans; Platelet Transfusion; Trioxsalen; Ultr | 1994 |
Factors influencing virus inactivation and retention of platelet properties following treatment with aminomethyltrimethylpsoralen and ultraviolet A light.
Topics: Blood; Blood Platelets; Blood Preservation; Hematocrit; Humans; Oxygen; Photochemistry; Trioxsalen; | 1992 |