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trioxsalen and Viral Diseases

trioxsalen has been researched along with Viral Diseases in 2 studies

Trioxsalen: Pigmenting photosensitizing agent obtained from several plants, mainly Psoralea corylifolia. It is administered either topically or orally in conjunction with ultraviolet light in the treatment of vitiligo.
lactone : Any cyclic carboxylic ester containing a 1-oxacycloalkan-2-one structure, or an analogue having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.
antipsoriatic : A drug used to treat psoriasis.
trioxsalen : 7H-Furo[3,2-g]chromen-7-one in which positions 2, 5, and 9 are substituted by methyl groups. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered orally in conjunction with UV-A for phototherapy treatment of vitiligo. After photoactivation it creates interstrand cross-links in DNA, inhibiting DNA synthesis and cell division, and can lead to cell injury; recovery from the cell injury may be followed by increased melanisation of the epidermis.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Margolis-Nunno, H1
Robinson, R1
Ben-Hur, E1
Horowitz, B1
Moroff, G1
Wagner, S1
Benade, L1
Dodd, RY1

Other Studies

2 other studies available for trioxsalen and Viral Diseases

ArticleYear
Quencher-enhanced specificity of psoralen-photosensitized virus inactivation in platelet concentrates.
    Transfusion, 1994, Volume: 34, Issue:9

    Topics: Antiviral Agents; Bacteriophage M13; Blood Platelets; Humans; Platelet Transfusion; Trioxsalen; Ultr

1994
Factors influencing virus inactivation and retention of platelet properties following treatment with aminomethyltrimethylpsoralen and ultraviolet A light.
    Blood cells, 1992, Volume: 18, Issue:1

    Topics: Blood; Blood Platelets; Blood Preservation; Hematocrit; Humans; Oxygen; Photochemistry; Trioxsalen;

1992