trioxsalen has been researched along with Mouth Diseases in 2 studies
Trioxsalen: Pigmenting photosensitizing agent obtained from several plants, mainly Psoralea corylifolia. It is administered either topically or orally in conjunction with ultraviolet light in the treatment of vitiligo.
lactone : Any cyclic carboxylic ester containing a 1-oxacycloalkan-2-one structure, or an analogue having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.
antipsoriatic : A drug used to treat psoriasis.
trioxsalen : 7H-Furo[3,2-g]chromen-7-one in which positions 2, 5, and 9 are substituted by methyl groups. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered orally in conjunction with UV-A for phototherapy treatment of vitiligo. After photoactivation it creates interstrand cross-links in DNA, inhibiting DNA synthesis and cell division, and can lead to cell injury; recovery from the cell injury may be followed by increased melanisation of the epidermis.
Mouth Diseases: Diseases involving the MOUTH.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kuusilehto, A | 2 |
| Lehtinen, R | 2 |
| Happonen, RP | 1 |
| Heikinheimo, K | 1 |
| Lehtimäki, K | 1 |
| Jansén, CT | 2 |
1 trial available for trioxsalen and Mouth Diseases
| Article | Year |
|---|---|
An open clinical trial of a new mouth-PUVA variant in the treatment of oral lichenoid lesions.
Topics: Administration, Topical; Adolescent; Adult; Aged; Feasibility Studies; Female; Follow-Up Studies; Hu | 1997 |
1 other study available for trioxsalen and Mouth Diseases
| Article | Year |
|---|---|
Comparison of the minimal phototoxic dose in topical 4,5', 8-trimethylpsoralen PUVA treatment of caucasian skin and of oral mucous membrane.
Topics: Administration, Topical; Adult; Female; Humans; Lichen Planus; Male; Mouth Diseases; Mouth Mucosa; P | 1990 |