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trioxsalen and Leukemia, Myeloid, Acute

trioxsalen has been researched along with Leukemia, Myeloid, Acute in 1 studies

Trioxsalen: Pigmenting photosensitizing agent obtained from several plants, mainly Psoralea corylifolia. It is administered either topically or orally in conjunction with ultraviolet light in the treatment of vitiligo.
lactone : Any cyclic carboxylic ester containing a 1-oxacycloalkan-2-one structure, or an analogue having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.
antipsoriatic : A drug used to treat psoriasis.
trioxsalen : 7H-Furo[3,2-g]chromen-7-one in which positions 2, 5, and 9 are substituted by methyl groups. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered orally in conjunction with UV-A for phototherapy treatment of vitiligo. After photoactivation it creates interstrand cross-links in DNA, inhibiting DNA synthesis and cell division, and can lead to cell injury; recovery from the cell injury may be followed by increased melanisation of the epidermis.

Leukemia, Myeloid, Acute: Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Berger, CL1
Cantor, C1
Welsh, J1
Dervan, P1
Begley, T1
Grant, S1
Gasparro, FP1
Edelson, RL1

Other Studies

1 other study available for trioxsalen and Leukemia, Myeloid, Acute

ArticleYear
Comparison of synthetic psoralen derivatives and 8-MOP in the inhibition of lymphocyte proliferation.
    Annals of the New York Academy of Sciences, 1985, Volume: 453

    Topics: Cell Line; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Furocoumarins; H

1985