trioxsalen has been researched along with Chronic Illness in 2 studies
Trioxsalen: Pigmenting photosensitizing agent obtained from several plants, mainly Psoralea corylifolia. It is administered either topically or orally in conjunction with ultraviolet light in the treatment of vitiligo.
lactone : Any cyclic carboxylic ester containing a 1-oxacycloalkan-2-one structure, or an analogue having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.
antipsoriatic : A drug used to treat psoriasis.
trioxsalen : 7H-Furo[3,2-g]chromen-7-one in which positions 2, 5, and 9 are substituted by methyl groups. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered orally in conjunction with UV-A for phototherapy treatment of vitiligo. After photoactivation it creates interstrand cross-links in DNA, inhibiting DNA synthesis and cell division, and can lead to cell injury; recovery from the cell injury may be followed by increased melanisation of the epidermis.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jansén, CT | 1 |
| Karvonen, J | 1 |
| Malmiharju, T | 1 |
| Lassus, A | 1 |
| Lauharanta, J | 1 |
| Eskelinen, A | 1 |
2 trials available for trioxsalen and Chronic Illness
| Article | Year |
|---|---|
PUVA therapy for polymorphous light eruptions: comparison of systemic methoxsalen and topical trioxsalen regimens and evaluation of local protective mechanisms.
Topics: Administration, Oral; Administration, Topical; Adolescent; Adult; Aged; Baths; Chronic Disease; Drug | 1982 |
The effect of etretinate compared with different regimens of PUVA in the treatment of persistent palmoplantar pustulosis.
Topics: Chronic Disease; Etretinate; Female; Foot Dermatoses; Hand Dermatoses; Humans; Male; Methoxsalen; Mi | 1985 |