trioxsalen has been researched along with Cancer of Cervix in 2 studies
Trioxsalen: Pigmenting photosensitizing agent obtained from several plants, mainly Psoralea corylifolia. It is administered either topically or orally in conjunction with ultraviolet light in the treatment of vitiligo.
lactone : Any cyclic carboxylic ester containing a 1-oxacycloalkan-2-one structure, or an analogue having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.
antipsoriatic : A drug used to treat psoriasis.
trioxsalen : 7H-Furo[3,2-g]chromen-7-one in which positions 2, 5, and 9 are substituted by methyl groups. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered orally in conjunction with UV-A for phototherapy treatment of vitiligo. After photoactivation it creates interstrand cross-links in DNA, inhibiting DNA synthesis and cell division, and can lead to cell injury; recovery from the cell injury may be followed by increased melanisation of the epidermis.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (100.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Yamayoshi, A | 2 |
Kato, K | 1 |
Suga, S | 1 |
Ichinoe, A | 1 |
Arima, T | 1 |
Matsuda, T | 1 |
Kato, H | 1 |
Murakami, A | 2 |
Wake, N | 2 |
Iwase, R | 1 |
Nishida, J | 1 |
Yamaoka, T | 1 |
2 other studies available for trioxsalen and Cancer of Cervix
Article | Year |
---|---|
Specific apoptosis induction in human papillomavirus-positive cervical carcinoma cells by photodynamic antisense regulation.
Topics: Animals; Apoptosis; Base Sequence; Carcinoma; Cell Line, Tumor; Cell Proliferation; DNA-Binding Prot | 2007 |
Photodynamic antisense regulation of human cervical carcinoma cell growth using psoralen-conjugated oligo(nucleoside phosphorothioate).
Topics: Cross-Linking Reagents; DNA; Female; Ficusin; Gene Expression; Humans; Oligonucleotides, Antisense; | 2001 |