Page last updated: 2024-11-05

trioxsalen and Bullous Dermatoses

trioxsalen has been researched along with Bullous Dermatoses in 1 studies

Trioxsalen: Pigmenting photosensitizing agent obtained from several plants, mainly Psoralea corylifolia. It is administered either topically or orally in conjunction with ultraviolet light in the treatment of vitiligo.
lactone : Any cyclic carboxylic ester containing a 1-oxacycloalkan-2-one structure, or an analogue having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.
antipsoriatic : A drug used to treat psoriasis.
trioxsalen : 7H-Furo[3,2-g]chromen-7-one in which positions 2, 5, and 9 are substituted by methyl groups. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered orally in conjunction with UV-A for phototherapy treatment of vitiligo. After photoactivation it creates interstrand cross-links in DNA, inhibiting DNA synthesis and cell division, and can lead to cell injury; recovery from the cell injury may be followed by increased melanisation of the epidermis.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lassus, A1
Lauharanta, J1
Eskelinen, A1

Trials

1 trial available for trioxsalen and Bullous Dermatoses

ArticleYear
The effect of etretinate compared with different regimens of PUVA in the treatment of persistent palmoplantar pustulosis.
    The British journal of dermatology, 1985, Volume: 112, Issue:4

    Topics: Chronic Disease; Etretinate; Female; Foot Dermatoses; Hand Dermatoses; Humans; Male; Methoxsalen; Mi

1985