trioxsalen has been researched along with Anemia, Aplastic in 4 studies
Trioxsalen: Pigmenting photosensitizing agent obtained from several plants, mainly Psoralea corylifolia. It is administered either topically or orally in conjunction with ultraviolet light in the treatment of vitiligo.
lactone : Any cyclic carboxylic ester containing a 1-oxacycloalkan-2-one structure, or an analogue having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.
antipsoriatic : A drug used to treat psoriasis.
trioxsalen : 7H-Furo[3,2-g]chromen-7-one in which positions 2, 5, and 9 are substituted by methyl groups. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered orally in conjunction with UV-A for phototherapy treatment of vitiligo. After photoactivation it creates interstrand cross-links in DNA, inhibiting DNA synthesis and cell division, and can lead to cell injury; recovery from the cell injury may be followed by increased melanisation of the epidermis.
Anemia, Aplastic: A form of anemia in which the bone marrow fails to produce adequate numbers of peripheral blood elements.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fendrick, JL | 1 |
| Hallick, LM | 1 |
| Papadopoulo, D | 2 |
| Porfirio, B | 1 |
| Moustacchi, E | 2 |
| Coppey, J | 1 |
| Sala-Trepat, M | 1 |
| Lopez, B | 1 |
| Averbeck, D | 1 |
4 other studies available for trioxsalen and Anemia, Aplastic
| Article | Year |
|---|---|
Psoralen photoinactivation of herpes simplex virus: monoadduct and cross-link repair by xeroderma pigmentosum and Fanconi's anemia cells.
Topics: Anemia, Aplastic; Cell Line; Cross-Linking Reagents; DNA Repair; Fanconi Anemia; Furocoumarins; Huma | 1984 |
Mutagenic response of Fanconi's anemia cells from a defined complementation group after treatment with photoactivated bifunctional psoralens.
Topics: Anemia, Aplastic; Cell Survival; Fanconi Anemia; Furocoumarins; Humans; Hypoxanthine Phosphoribosylt | 1990 |
Multiplicity reactivation and mutagenesis of trimethylpsoralen-damaged herpes virus in normal and Fanconi's anaemia cells.
Topics: Adult; Anemia, Aplastic; Child; Dose-Response Relationship, Drug; Fanconi Anemia; Fibroblasts; Furoc | 1989 |
Repair of 4,5',8-trimethylpsoralen plus light-induced DNA damage in normal and Fanconi's anemia cell lines.
Topics: Anemia, Aplastic; Cell Line; Cell Survival; DNA; DNA Damage; DNA Repair; Fanconi Anemia; Furocoumari | 1988 |