trioxsalen has been researched along with Anasarca in 2 studies
Trioxsalen: Pigmenting photosensitizing agent obtained from several plants, mainly Psoralea corylifolia. It is administered either topically or orally in conjunction with ultraviolet light in the treatment of vitiligo.
lactone : Any cyclic carboxylic ester containing a 1-oxacycloalkan-2-one structure, or an analogue having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.
antipsoriatic : A drug used to treat psoriasis.
trioxsalen : 7H-Furo[3,2-g]chromen-7-one in which positions 2, 5, and 9 are substituted by methyl groups. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered orally in conjunction with UV-A for phototherapy treatment of vitiligo. After photoactivation it creates interstrand cross-links in DNA, inhibiting DNA synthesis and cell division, and can lead to cell injury; recovery from the cell injury may be followed by increased melanisation of the epidermis.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The most potent compound, namely TRX derivative 3, was studied for its anti-inflammatory activity in vivo on rat paw edema induced by carrageenan, and was found to be of almost identical activity to indomethacin." | 3.75 | Trioxsalen derivatives with lipoxygenase inhibitory activity. ( Athanassopoulos, CM; E Bariamis, S; Hadjipavlou-Litina, D; Militsopoulou, M; Papaioannou, D, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hadjipavlou-Litina, D | 1 |
| E Bariamis, S | 1 |
| Militsopoulou, M | 1 |
| Athanassopoulos, CM | 1 |
| Papaioannou, D | 1 |
| Marciani, S | 1 |
| Guiotto, A | 1 |
| Rodighiero, P | 1 |
| Gia, O | 1 |
| Rodighiero, G | 1 |
| Pathak, MA | 1 |
2 other studies available for trioxsalen and Anasarca
| Article | Year |
|---|---|
Trioxsalen derivatives with lipoxygenase inhibitory activity.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Biphenyl Compounds; Carrageenan; Edema; Female; Fre | 2009 |
Synthesis and photobiological properties of 4,8-dimethyl-5'-carboxypsoralen: a major metabolite of 4,5',8-trimethylpsoralen.
Topics: Administration, Oral; Administration, Topical; Animals; Binding Sites; DNA; Edema; Erythema; Furocou | 1979 |