Page last updated: 2024-11-05

trioxsalen and Anasarca

trioxsalen has been researched along with Anasarca in 2 studies

Trioxsalen: Pigmenting photosensitizing agent obtained from several plants, mainly Psoralea corylifolia. It is administered either topically or orally in conjunction with ultraviolet light in the treatment of vitiligo.
lactone : Any cyclic carboxylic ester containing a 1-oxacycloalkan-2-one structure, or an analogue having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.
antipsoriatic : A drug used to treat psoriasis.
trioxsalen : 7H-Furo[3,2-g]chromen-7-one in which positions 2, 5, and 9 are substituted by methyl groups. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered orally in conjunction with UV-A for phototherapy treatment of vitiligo. After photoactivation it creates interstrand cross-links in DNA, inhibiting DNA synthesis and cell division, and can lead to cell injury; recovery from the cell injury may be followed by increased melanisation of the epidermis.

Research Excerpts

ExcerptRelevanceReference
" The most potent compound, namely TRX derivative 3, was studied for its anti-inflammatory activity in vivo on rat paw edema induced by carrageenan, and was found to be of almost identical activity to indomethacin."3.75Trioxsalen derivatives with lipoxygenase inhibitory activity. ( Athanassopoulos, CM; E Bariamis, S; Hadjipavlou-Litina, D; Militsopoulou, M; Papaioannou, D, 2009)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hadjipavlou-Litina, D1
E Bariamis, S1
Militsopoulou, M1
Athanassopoulos, CM1
Papaioannou, D1
Marciani, S1
Guiotto, A1
Rodighiero, P1
Gia, O1
Rodighiero, G1
Pathak, MA1

Other Studies

2 other studies available for trioxsalen and Anasarca

ArticleYear
Trioxsalen derivatives with lipoxygenase inhibitory activity.
    Journal of enzyme inhibition and medicinal chemistry, 2009, Volume: 24, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Biphenyl Compounds; Carrageenan; Edema; Female; Fre

2009
Synthesis and photobiological properties of 4,8-dimethyl-5'-carboxypsoralen: a major metabolite of 4,5',8-trimethylpsoralen.
    Il Farmaco; edizione scientifica, 1979, Volume: 34, Issue:3

    Topics: Administration, Oral; Administration, Topical; Animals; Binding Sites; DNA; Edema; Erythema; Furocou

1979