triolein and Pancreatic-Neoplasms

A double-tracer technique to estimate lipid digestion was investigated. 3H-labelled oleic acid and 14C-labelled triolein were ingested in a test meal. The serum radioactivity of 3H after ingestion of labelled oleic acid depends on absorption and metabolism of free fatty acids, while serum radioactivity of 14C from triolein, in addition to the former, depends on triglycerol digestion. This study shows that the ratio between 3H and 14C 2h after the test meal gives a good qualitative and quantitative estimation of lipid digestion: the 3H/14C ratio in patients with maldigestion is significantly higher than for normals (P less than 0.01), the predictive value of the 3H/14C ratio in the diagnosis of maldigestion is high, that of a positive result being 1.0 and that of a negative 0.93, and quantitatively the 3H/14C ratio shows a highly significant correlation with faecal fat (P less than 0.001). The test is very easy to perform, lasts for only 2 h, and is without discomfort to the patient or nursing and laboratory staff. It gives information like or superior to that of faecal fat measurement.

Topics: Adult; Aged; Celiac Disease; Dietary Fats; Feces; Female; Humans; Malabsorption Syndromes; Male; Middle Aged; Oleic Acids; Pancreatic Juice; Pancreatic Neoplasms; Pancreatitis; Triolein

Topics: Abdominal Neoplasms; Adolescent; Adult; Aged; Breast Neoplasms; Carcinoma; Child; Cobalt Isotopes; Female; Gastric Juice; Gastrointestinal Neoplasms; Genital Neoplasms, Female; Hodgkin Disease; Humans; Intestinal Mucosa; Iodine Isotopes; Leiomyosarcoma; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Male; Mesothelioma; Methods; Middle Aged; Neuroblastoma; Pancreatic Neoplasms; Povidone; Radiation Effects; Radioisotope Teletherapy; Splenic Neoplasms; Time Factors; Triolein; Vitamin B 12

Topics: Aged; Amylases; Bicarbonates; Blood Glucose; Blood Proteins; Cholecystokinin; Chymotrypsin; Diet Therapy; Female; Humans; Injections, Intravenous; Intestinal Absorption; Intestinal Secretions; Iodine Isotopes; Jejunum; Lipids; Pancreatectomy; Pancreatic Neoplasms; Secretin; Serum Albumin, Radio-Iodinated; Triolein; Trypsin

Topics: Cholestasis; Chronic Disease; Diabetes Mellitus; Dietary Fats; Fats; Feces; Gastrectomy; Hepatitis A; Humans; Intestinal Absorption; Iodine Radioisotopes; Liver Cirrhosis; Pancreatic Neoplasms; Triolein

Topics: Female; Gastrectomy; Humans; Intestinal Absorption; Iodine Isotopes; Lipid Metabolism; Male; Pancreas; Pancreatic Neoplasms; Stomach Neoplasms; Stomach Ulcer; Triolein

Topics: Absorption; Bile Acids and Salts; Celiac Disease; Dietary Fats; Gallstones; Hepatitis; Humans; Iodine Isotopes; Jaundice; Jaundice, Obstructive; Lipid Metabolism; Pancreas; Pancreatic Neoplasms; Pancreatitis; Salts; Triolein

Topics: Absorption; Bronchial Neoplasms; Celiac Disease; Dietary Fats; Digestion; Dumping Syndrome; Feces; Gastrectomy; Humans; Iodine Isotopes; Lipid Metabolism; Lipids; Liver Cirrhosis; Liver Neoplasms; Oleic Acid; Oleic Acids; Pancreatic Neoplasms; Pancreatitis; Triolein

Topics: Aminopeptidases; Amylases; Blood Chemical Analysis; Body Fluids; Carbohydrates; Cholecystokinin; Clinical Enzyme Tests; Diagnosis; Gastrointestinal Hormones; Humans; Iodine Isotopes; Leucine; Lipase; Metabolism; Pancreatic Neoplasms; Pancreatitis; Secretin; Triolein; Trypsin; Urine

Topics: Carbohydrate Metabolism; Iodine Isotopes; Lipid Metabolism; Oleic Acid; Pancreas; Pancreatic Juice; Pancreatic Neoplasms; Pancreatitis; Physiology; Triolein

Topics: Biliary Tract; Blood Chemical Analysis; Carotenoids; Celiac Disease; Colitis; Colitis, Ulcerative; Diarrhea; Dietary Fats; Emulsions; Enteritis; Enterocolitis; Feces; Gastrectomy; Glucose; Iodine Isotopes; Lipase; Liver Cirrhosis; Milk; Oleic Acid; Pancreatic Neoplasms; Pancreatitis; Sprue, Tropical; Triolein; Xylose

Topics: Absorption; Amyloidosis; Celiac Disease; Diarrhea; Fats; Feces; Gastrectomy; Intestinal Absorption; Intestines; Iodine Isotopes; Lipid Metabolism; Lipids; Oleic Acid; Pancreatic Neoplasms; Pancreatitis; Sprue, Tropical; Triolein; Vitamin A

Topics: Calculi; Fatty Acids; Iodine Isotopes; Metabolism; Neoplasms; Oleic Acid; Pancreas; Pancreatic Cyst; Pancreatic Neoplasms; Pancreatitis; Radiometry; Triolein

Topics: Celiac Disease; Cholelithiasis; Crohn Disease; Enteritis; Exocrine Pancreatic Insufficiency; Hyperlipidemias; Hyperlipoproteinemia Type I; Hyperlipoproteinemia Type III; Iodine Isotopes; Liver Diseases; Pancreatic Neoplasms; Pancreatitis; Radiometry; Sprue, Tropical; Triolein

Topics: Celiac Disease; Diarrhea; Feces; Intestinal Absorption; Intestinal Fistula; Intestines; Iodine Isotopes; Lipid Metabolism; Oleic Acid; Pancreatic Neoplasms; Pancreatitis; Pharmacology; Postgastrectomy Syndromes; Sprue, Tropical; Triolein; Vitamin A