triolein has been researched along with Mucopolysaccharidosis-III* in 1 studies
1 other study(ies) available for triolein and Mucopolysaccharidosis-III
| Article | Year |
|---|---|
Impaired mitophagy in Sanfilippo a mice causes hypertriglyceridemia and brown adipose tissue activation.
Lysosomal storage diseases result in various developmental and physiological complications, including cachexia. To study the causes for the negative energy balance associated with cachexia, we assessed the impact of sulfamidase deficiency and heparan sulfate storage on energy homeostasis and metabolism in a mouse model of type IIIa mucopolysaccharidosis (MPS IIIa, Sanfilippo A syndrome). At 12-weeks of age, MPS IIIa mice exhibited fasting and postprandial hypertriglyceridemia compared with wildtype mice, with a reduction of white and brown adipose tissues. Partitioning of dietary [ Topics: Adipose Tissue, Brown; Animals; Cachexia; Hypertriglyceridemia; Mice; Mitophagy; Mucopolysaccharidosis III; Triolein | 2022 |