trinitrobenzenesulfonic acid has been researched along with Irritable Bowel Syndrome in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (23.33) | 29.6817 |
| 2010's | 20 (66.67) | 24.3611 |
| 2020's | 3 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, X; Liu, P; Lv, M; Shi, Z; Tang, X; Wang, F; Wu, H; Zhang, K; Zhang, M; Zheng, Y | 1 |
| Brierley, SM; Daly, DM; Garcia-Caraballo, S; Grundy, D; Grundy, L; Konthapakdee, N; O'Donnell, T | 1 |
| Bao, CH; Jin, XM; Li, GN; Liu, HR; Shi, Z; Wang, CY; Wang, D; Wang, XM; Wu, HG; Wu, LY; Yan, YL | 1 |
| Brierley, SM; Bunnett, NW; Castro, J; Chang, L; Dong, X; Garcia-Caraballo, S; Ghetti, A; Grundy, L; Harrington, AM; Lieu, T; Lumsden, AL; Maddern, J; Miller, P; O'Donnell, T; Poole, DP; Schober, G; Steinhoff, MS | 1 |
| Cui, X; Li, GQ; Liu, Y; Wang, XH; Xu, LQ; Yang, WR; Zhao, Q; Zuo, XL | 1 |
| Chen, L; Geng, H; Pei, LX; Song, YF; Sun, JH; Wu, J; Xu, WL; Yuan, MQ; Zhou, JY | 1 |
| Chang, ZP; Deng, GF; Feng, XJ; Gao, JP; Guo, Y; Hou, RG; Liu, JJ; Shao, YY; Xu, D | 1 |
| Beaufrand, C; Boulete, IM; Eddy, EP; Eutamene, H; Foss, JA; Joshi, A; Palejwala, VA; Patwa, V; Shailubhai, K; Thadi, A; Theodorou, V | 1 |
| Basbaum, A; Bosmans, F; Braz, J; Brierley, SM; Castro, J; Deiteren, A; Erickson, A; Gilchrist, J; Grundy, L; King, GF; Li, Q; Pasricha, PJ; Rais, R; Rychkov, GY; Salvatierra, J; Slusher, BS | 1 |
| Brierley, SM; Castro, J; Deiteren, A; Feil, R; Garcia-Caraballo, S; Ge, P; Ghetti, A; Grundy, L; Hannig, G; Harrington, AM; Kurtz, CB; Maddern, J; Miller, P; Peters, S; Rychkov, GY; Silos-Santiago, I | 1 |
| Blackshaw, LA; Brierley, SM; Castro, J; Cohen, MB; Currie, MG; Ge, P; Hannig, G; Harrington, AM; Hughes, PA; Jacobson, S; Jin, H; Johnston, JM; Kurtz, CB; Lavins, BJ; MacDougall, JE; Mann, E; Martin, CM; Shea, CM; Silos-Santiago, I | 1 |
| Anderson, EM; Caudle, RM; Del Valle-Pinero, AY; Henderson, WA; Sherwin, LB | 1 |
| Huang, Y; Huang, Z; Shi, J; Wang, Y | 1 |
| Bian, ZX; Chen, T; Kang, N; Su, M; Tang, XD; Wang, FY; Wang, XG; Zheng, YQ; Zhu, EL | 1 |
| Han, M; Huang, J; Ma, K; Ma, YR; Qin, HY; Rao, Z; Shao, YY; Wu, XA | 1 |
| Ashley Blackshaw, L; Brierley, SM; Campaniello, MA; Harrington, AM; Hughes, PA; Martin, CM | 1 |
| Barrachina, MD; Calatayud, S; Cosín-Roger, J; Esplugues, JV; Hernández, C; Macias-Ceja, DC; Ortiz-Masiá, D; Salvador, P | 1 |
| Chen, FX; Li, LX; Li, YQ; Qi, QQ; Wang, P; Zhao, DY; Zuo, XL | 1 |
| Fukudo, S; Hasegawa, R; Ito, H; Nagura, Y; Saito-Nakaya, K | 1 |
| Blackshaw, LA; Brierley, SM; Brookes, SJ; Hughes, PA; Linden, DR; Martin, CM | 1 |
| Gale, JD; Kurebayashi, Y; Ohashi-Doi, K | 1 |
| Campbell-Dittmeyer, K; Chaplan, SR; Greenwood-Van Meerveld, B; Tyler, K; Wickenden, AD; Wiskur, BJ | 1 |
| Hong, S; Jung, Y; Kang, S; Kim, YM; Min, D; Yoo, HJ; Yoon, JH; Yum, S | 1 |
| Berman, BM; Bian, ZX; Qin, HY; Sung, JJ; Wu, JC; Xiao, HT | 1 |
| Adam, B; Bartholomeusz, FD; Holtmann, G; Liebregts, T; Tsopelas, C | 1 |
| Ardid, D; Bertrand, C; Delafoy, L; Diop, L; Doherty, AM; Eschalier, A; Gelot, A | 1 |
| Adam, B; Gschossmann, JM; Holtmann, G; Krippner, C; Liebregts, T; Ruwe, M; Scholl, F | 1 |
| Akbarali, HI; Foreman, RD; Greenwood-van Meerveld, B; Lupu, F; Malykhina, AP; Qin, C | 1 |
| Iwata, H; Kawai, M; Kurebayashi, Y; Ohashi, K; Sato, Y | 1 |
| Kikuchi, A; Ohashi, K; Omura, H; Sugie, Y; Sugimoto, H | 1 |
1 trial(s) available for trinitrobenzenesulfonic acid and Irritable Bowel Syndrome
| Article | Year |
|---|---|
Linaclotide inhibits colonic nociceptors and relieves abdominal pain via guanylate cyclase-C and extracellular cyclic guanosine 3',5'-monophosphate.
Topics: Abdominal Pain; Adult; Aged; Aged, 80 and over; Animals; Caco-2 Cells; Cell Line; Colon; Cyclic GMP; Disease Models, Animal; Double-Blind Method; Female; Guanylate Cyclase; Humans; Irritable Bowel Syndrome; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Natriuretic Peptides; Nociceptors; Peptides; Receptors, Atrial Natriuretic Factor; Receptors, Enterotoxin; Receptors, Guanylate Cyclase-Coupled; Receptors, Peptide; Treatment Outcome; Trinitrobenzenesulfonic Acid | 2013 |
29 other study(ies) available for trinitrobenzenesulfonic acid and Irritable Bowel Syndrome
| Article | Year |
|---|---|
Tong-Xie-Yao-Fang alleviates diarrhea-predominant irritable bowel syndrome in rats via the GCN2/PERK-eIF2α-ATF4 signaling pathway.
Topics: Activating Transcription Factor 4; Animals; Body Weight; Caspase 3; Cysteine; Diarrhea; Drugs, Chinese Herbal; eIF-2 Kinase; Eukaryotic Initiation Factor-2; gamma-Aminobutyric Acid; Glycine; Irritable Bowel Syndrome; Lysine; Maternal Deprivation; Proto-Oncogene Proteins c-bcl-2; Rats; Signal Transduction; Trinitrobenzenesulfonic Acid; Water | 2022 |
Serotonin exerts a direct modulatory role on bladder afferent firing in mice.
Topics: Afferent Pathways; Animals; Colon; Disease Models, Animal; Female; Ganglia, Spinal; Granisetron; Irritable Bowel Syndrome; Male; Mice; Mice, Inbred C57BL; Neurons; Neurons, Afferent; Peripheral Nervous System; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins; Trinitrobenzenesulfonic Acid; Urinary Bladder | 2019 |
Effect of mild moxibustion on intestinal microbiota and NLRP6 inflammasome signaling in rats with post-inflammatory irritable bowel syndrome.
Topics: Animals; Disease Models, Animal; Gastrointestinal Microbiome; Humans; Inflammasomes; Inflammation; Intestinal Mucosa; Irritable Bowel Syndrome; Male; Moxibustion; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Receptors, Vasopressin; Signal Transduction; Specific Pathogen-Free Organisms; Trinitrobenzenesulfonic Acid | 2019 |
Activation of pruritogenic TGR5, MrgprA3, and MrgprC11 on colon-innervating afferents induces visceral hypersensitivity.
Topics: Abdominal Pain; Adolescent; Adult; Animals; Colon; Disease Models, Animal; Female; Ganglia, Spinal; Healthy Volunteers; Humans; Intestinal Mucosa; Irritable Bowel Syndrome; Male; Mice; Middle Aged; Nociception; Receptors, G-Protein-Coupled; Sensory Receptor Cells; Trinitrobenzenesulfonic Acid; Young Adult | 2019 |
Topics: Animals; Clostridium butyricum; Dendritic Cells; Disease Models, Animal; Humans; Immunity, Mucosal; Intestinal Mucosa; Irritable Bowel Syndrome; Male; Mice; Mice, Inbred C57BL; Probiotics; Treatment Outcome; Trinitrobenzenesulfonic Acid | 2019 |
Electroacupuncture Relieves Irritable Bowel Syndrome by Regulating IL-18 and Gut Microbial Dysbiosis in a Trinitrobenzene Sulfonic Acid-Induced Post-Inflammatory Animal Model.
Topics: Animals; Disease Models, Animal; Dysbiosis; Electroacupuncture; Gastrointestinal Microbiome; Interleukin-18; Irritable Bowel Syndrome; Male; Rats; Rats, Sprague-Dawley; Trinitrobenzenesulfonic Acid | 2020 |
Oridonin Attenuates TNBS-induced Post-inflammatory Irritable Bowel Syndrome via PXR/NF-κB Signaling.
Topics: Animals; Anti-Inflammatory Agents; Biomarkers; Blotting, Western; Caco-2 Cells; Diterpenes, Kaurane; Humans; Inflammation; Irritable Bowel Syndrome; Male; NF-kappa B; Permeability; Pregnane X Receptor; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Signal Transduction; Tight Junctions; Treatment Outcome; Trinitrobenzenesulfonic Acid | 2021 |
Oral treatment with plecanatide or dolcanatide attenuates visceral hypersensitivity
Topics: Administration, Oral; Animals; Caco-2 Cells; Colon; Constipation; Dextrans; Female; Fluorescein-5-isothiocyanate; Guanylyl Cyclase C Agonists; Humans; Intestinal Mucosa; Irritable Bowel Syndrome; Lipopolysaccharides; Male; Natriuretic Peptides; Nociception; Peptides; Permeability; Rats; Rats, Sprague-Dawley; Receptors, Enterotoxin; Signal Transduction; Tight Junctions; Trinitrobenzenesulfonic Acid; Visceral Pain | 2018 |
NaV1.1 inhibition can reduce visceral hypersensitivity.
Topics: Animals; Chronic Pain; Colon; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Stability; Ganglia, Spinal; Humans; Irritable Bowel Syndrome; Male; Maximum Tolerated Dose; Mice; NAV1.1 Voltage-Gated Sodium Channel; Nociceptors; Pain Measurement; Trinitrobenzenesulfonic Acid; Visceral Pain; Voltage-Gated Sodium Channel Blockers | 2018 |
Chronic linaclotide treatment reduces colitis-induced neuroplasticity and reverses persistent bladder dysfunction.
Topics: Afferent Pathways; Animals; Colitis; Colon; Disease Models, Animal; Drug Administration Schedule; Guanylyl Cyclase C Agonists; Humans; Hyperalgesia; Irritable Bowel Syndrome; Male; Mice; Neuronal Plasticity; Nociception; Peptides; Treatment Outcome; Trinitrobenzenesulfonic Acid; Urinary Bladder; Urinary Bladder, Overactive | 2018 |
Altered vasoactive intestinal peptides expression in irritable bowel syndrome patients and rats with trinitrobenzene sulfonic acid-induced colitis.
Topics: Adult; Animals; Biomarkers; Case-Control Studies; Colitis; Colon; Disease Models, Animal; Female; Gene Expression Regulation; Humans; Hyperalgesia; Inflammation Mediators; Irritable Bowel Syndrome; Male; Middle Aged; Pain Threshold; Peroxidase; Pilot Projects; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Time Factors; Trinitrobenzenesulfonic Acid; Vasoactive Intestinal Peptide; Visceral Pain; Weight Loss; Young Adult | 2015 |
The Protective Effects of Exclusive Enteral Nutrition Formulas on Growth Factor Expression and the Proximal Tibial Epiphyseal Growth Plate in a TNBS-Induced IBD Rat Model.
Topics: Animals; Bone Development; Diet; Dietary Supplements; Enteral Nutrition; Gene Expression Regulation; Growth Plate; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Irritable Bowel Syndrome; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Somatotropin; RNA, Messenger; Tibia; Trinitrobenzenesulfonic Acid | 2015 |
Herbal prescription Chang'an II repairs intestinal mucosal barrier in rats with post-inflammation irritable bowel syndrome.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents; Behavior, Animal; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Colitis; Colon; Disease Models, Animal; Drug Combinations; Drugs, Chinese Herbal; Feces; Feeding Behavior; Food Preferences; Gastrointestinal Agents; Immunity, Mucosal; Inflammation Mediators; Interleukin-1beta; Interleukin-4; Intestinal Mucosa; Irritable Bowel Syndrome; Male; Medicine, Chinese Traditional; Motor Activity; Pain Threshold; Rats, Sprague-Dawley; Trinitrobenzenesulfonic Acid; Wound Healing | 2015 |
Serum serotonin reduced the expression of hepatic transporter Mrp2 and P-gp via regulating nuclear receptor CAR in PI-IBS rats.
Topics: 5-Hydroxytryptophan; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Colon; Constitutive Androstane Receptor; Disease Models, Animal; Enterochromaffin Cells; Fenclonine; Irritable Bowel Syndrome; Liver; Male; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Serotonin; Signal Transduction; Trinitrobenzenesulfonic Acid | 2015 |
Activation of colo-rectal high-threshold afferent nerves by Interleukin-2 is tetrodotoxin-sensitive and upregulated in a mouse model of chronic visceral hypersensitivity.
Topics: Adaptive Immunity; Afferent Pathways; Animals; Colitis; Disease Models, Animal; Ganglia, Spinal; Hyperalgesia; Interleukin-2; Irritable Bowel Syndrome; Mice; NAV1.7 Voltage-Gated Sodium Channel; Neurons, Afferent; Peroxidase; Real-Time Polymerase Chain Reaction; Receptors, Interleukin-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium Channel Blockers; Tetrodotoxin; Trinitrobenzenesulfonic Acid; Visceral Pain | 2016 |
The flesh ethanolic extract of Hylocereus polyrhizus exerts anti-inflammatory effects and prevents murine colitis.
Topics: Animals; Anti-Inflammatory Agents; Cactaceae; Colitis; Colon; Cytokines; Disease Models, Animal; Ethanol; Flavonoids; Fruit; Gene Expression; Irritable Bowel Syndrome; Mice; Mice, Inbred BALB C; Phytotherapy; Plant Extracts; Polyphenols; Trinitrobenzenesulfonic Acid | 2016 |
Colonic mucosal N-methyl-D-aspartate receptor mediated visceral hypersensitivity in a mouse model of irritable bowel syndrome.
Topics: Ammonia; Animals; Colon; Dilatation; Disease Models, Animal; Feces; Glutamic Acid; Intestinal Mucosa; Irritable Bowel Syndrome; Male; Mice, Inbred C57BL; Pain Threshold; Receptors, N-Methyl-D-Aspartate; Reflex; Trinitrobenzenesulfonic Acid; Viscera | 2016 |
Corticotropin-releasing hormone receptor 1 antagonist blocks colonic hypersensitivity induced by a combination of inflammation and repetitive colorectal distension.
Topics: Animals; Colitis; Colon; Dilatation, Pathologic; Electromyography; Humans; Inflammation; Irritable Bowel Syndrome; Male; Pyrimidines; Pyrroles; Rats; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone; Trinitrobenzenesulfonic Acid | 2008 |
Post-inflammatory colonic afferent sensitisation: different subtypes, different pathways and different time courses.
Topics: Afferent Pathways; Animals; Colitis; Colon; Irritable Bowel Syndrome; Male; Mechanoreceptors; Mice; Mice, Inbred C57BL; Splanchnic Nerves; Time Factors; Trinitrobenzenesulfonic Acid; Visceral Afferents | 2009 |
Pregabalin inhibits accelerated defecation and decreased colonic nociceptive threshold in sensitized rats.
Topics: Abdominal Pain; Analgesics; Animals; Defecation; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Irritable Bowel Syndrome; Male; Pain Threshold; Pregabalin; Rats; Rats, Sprague-Dawley; Restraint, Physical; Stress, Psychological; Trinitrobenzenesulfonic Acid | 2010 |
A novel TRPV1 receptor antagonist JNJ-17203212 attenuates colonic hypersensitivity in rats.
Topics: Acetic Acid; Administration, Oral; Aminopyridines; Animals; Colon; Disease Models, Animal; Dose-Response Relationship, Drug; Irritable Bowel Syndrome; Male; Piperazines; Rats; Rats, Wistar; Trinitrobenzenesulfonic Acid; TRPV Cation Channels | 2010 |
Colon-targeted cell-permeable NFκB inhibitory peptide is orally active against experimental colitis.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Blotting, Western; Caco-2 Cells; Cell Line, Tumor; Cell-Penetrating Peptides; Colon; Enzyme-Linked Immunosorbent Assay; Humans; Immunohistochemistry; Irritable Bowel Syndrome; Male; NF-kappa B; Peptides; Rats; Trinitrobenzenesulfonic Acid | 2012 |
Key factors in developing the trinitrobenzene sulfonic acid-induced post-inflammatory irritable bowel syndrome model in rats.
Topics: Animals; Colitis; Disease Models, Animal; Ethanol; Irritable Bowel Syndrome; Male; Rats; Rats, Sprague-Dawley; Trinitrobenzenesulfonic Acid | 2012 |
Host immune response determines visceral hyperalgesia in a rat model of post-inflammatory irritable bowel syndrome.
Topics: Animals; Colitis; Colon; Disease Models, Animal; Hyperalgesia; Interleukin-2; Interleukin-6; Irritable Bowel Syndrome; Male; Rats; Rats, Inbred F344; Rats, Inbred Lew; Trinitrobenzenesulfonic Acid | 2013 |
Interactive involvement of brain derived neurotrophic factor, nerve growth factor, and calcitonin gene related peptide in colonic hypersensitivity in the rat.
Topics: Animals; Antibodies, Monoclonal; Brain-Derived Neurotrophic Factor; Calcitonin Gene-Related Peptide; Catheterization; Colon; Dose-Response Relationship, Drug; Irritable Bowel Syndrome; Male; Models, Animal; Nerve Growth Factor; Nerve Tissue Proteins; Pain; Pain Threshold; Rats; Rats, Wistar; Trinitrobenzenesulfonic Acid | 2006 |
Severity of mucosal inflammation as a predictor for alterations of visceral sensory function in a rat model.
Topics: Abdominal Muscles; Acute Disease; Animals; Catheterization; Colitis; Colon; Dilatation, Pathologic; Disease Models, Animal; Electromyography; Enzyme-Linked Immunosorbent Assay; Hyperalgesia; Interleukin-2; Interleukin-6; Intestinal Mucosa; Irritable Bowel Syndrome; Male; Rats; Rats, Inbred Lew; Rectum; Sensation Disorders; Severity of Illness Index; Time Factors; Trinitrobenzenesulfonic Acid | 2006 |
Hyperexcitability of convergent colon and bladder dorsal root ganglion neurons after colonic inflammation: mechanism for pelvic organ cross-talk.
Topics: Action Potentials; Animals; Colon; Cystitis, Interstitial; Disease Models, Animal; Ganglia, Spinal; Immunohistochemistry; Inflammation; Irritable Bowel Syndrome; Male; Neurons; Rats; Rats, Sprague-Dawley; Trinitrobenzenesulfonic Acid; Urinary Bladder | 2006 |
Colonic mast cell infiltration in rats with TNBS-induced visceral hypersensitivity.
Topics: Animals; Colon; Dose-Response Relationship, Drug; Intestinal Mucosa; Irritable Bowel Syndrome; Male; Mast Cells; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Thioxanthenes; Trinitrobenzenesulfonic Acid; Xanthones | 2007 |
Pharmacological evaluation of a novel cannabinoid 2 (CB2) ligand, PF-03550096, in vitro and in vivo by using a rat model of visceral hypersensitivity.
Topics: Animals; Benzimidazoles; Camphanes; Cell Line; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Humans; Irritable Bowel Syndrome; Male; Pain; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Trinitrobenzenesulfonic Acid | 2008 |