trinitrobenzenesulfonic acid has been researched along with Crohn Disease in 151 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (7.28) | 18.2507 |
| 2000's | 33 (21.85) | 29.6817 |
| 2010's | 85 (56.29) | 24.3611 |
| 2020's | 22 (14.57) | 2.80 |
| Authors | Studies |
|---|---|
| Fichna, J; Jacenik, D; Krajewska, WM; Małecka-Panas, E; Mokrowiecka, A; Salaga, M; Zatorski, H; Zielińska, M | 1 |
| Gallyas, F; Kálmán, N; Kovács, D; Radnai, B; Schicho, R; Vámos, E; Vántus, VB | 1 |
| Chen, B; Chen, M; Han, J; Huang, S; Xu, S; Zeng, Z; Zhang, S; Zhou, G; Zhuang, X | 1 |
| Geesala, R; Lin, YM; Qiu, S; Shi, XZ; Zhang, K | 1 |
| Chen, T; Kuang, X; Li, Z; Shen, T; Wu, J | 1 |
| Li, X; Liu, Z; Peng, Y; Zhao, L | 1 |
| Ahmed, O; Alqurashi, T; Hussien, M; Murad, H | 1 |
| Bunnett, NW; Chupina Estrada, A; Fontenot, L; Ho, W; Jensen, DD; Koon, HW; Mattai, SA; Nelson, B; Rieder, F; Shih, DQ; Wang, J; Xie, Y | 1 |
| Chen, W; Chen, X; He, F; He, Y; Li, L; Lin, H; Liu, Q; Lu, J; Ni, B; Xu, R; Yang, F; Zhang, Q; Zheng, X; Zhong, X; Zou, X | 1 |
| Edelblum, KL; Kuo, WT; Nilsen, SP; Ong, MLDM; Shashikanth, N; Shen, L; Turner, JR; Wang, Y; Wu, L; Zha, J; Zuo, L | 1 |
| Castro-Ochoa, KF; Citalán-Madrid, AF; Schnoor, M; Vargas-Robles, H | 1 |
| Alam, MM; Huang, Y; Mathur, R; Zhao, XF; Zhu, X | 1 |
| Cazals-Hatem, D; Collard, M; Doblas, S; Flacs, M; Maggiori, L; Ogier-Denis, E; Panis, Y; Treton, X; Zappa, M | 1 |
| Al Nabhani, Z; Barreau, F; Berrebi, D; Cerf-Bensussan, N; Daniel, F; Dussaillant, M; Hugot, JP; Madre, C; Martinez-Vinson, C; Montcuquet, N; Ogier-Denis, E; Roy, M; Zouali, H | 1 |
| Chen, M; Li, J; Liu, L; Zhao, Q | 1 |
| Li, N; Shi, RH | 1 |
| Gao, R; Guo, L; Li, D; Luo, M; Wang, J; Wang, L; Wei, C; Wu, B; Xiong, F; Xu, Z; Yao, J; Yu, Z; Zhang, D | 1 |
| Dong, W; Huang, F; Mei, Y; Wang, J; Wu, J; Zhang, T | 1 |
| Blennerhassett, MG; Lourenssen, SR | 1 |
| Alcudia, A; Argüelles-Arias, F; De-Miguel, M; García-Montes, JM; Illanes, M; Macías-García, L; Motilva, V; Ortiz, T; Talero, E; Vázquez-Román, V | 1 |
| Bai, X; Ding, J; Guo, H; Jin, X; Liu, M; Liu, X; Pang, J; Yang, Y; Zhang, L; Zhang, Y | 1 |
| Allais, L; Bachert, C; Bracke, KR; Brusselle, GG; Cuvelier, CA; De Smet, R; De Vos, M; Devriese, S; Gonzales, GB; Laukens, D; Maes, T; Peeters, H; Van Crombruggen, K; Verschuere, S | 1 |
| Ding, H; Gong, Y; Jiao, Y; Qi, X; Qian, J; Sun, Y; Tang, L; Wang, H; Yang, H; Ying, P; Zhao, J; Zhou, J; Zhou, Y; Zhu, W | 1 |
| Chen, B; Chen, J; Huang, C; Tan, G; Zhi, F | 1 |
| Cui, Z; Liang, C; Liu, S; Min, L; Ning, T; Wang, T; Wang, X; Xie, S; Xu, J; Zhang, N; Zhang, S; Zhu, S | 1 |
| Ni, R; Qian, J; Tang, Q; Wang, L; Wu, H; Yan, L; Zhang, D; Zou, X | 1 |
| Arijs, I; Arnold, B; Breynaert, C; de Bruyn, M; De Hertogh, G; Ferrante, M; Geboes, K; Hu, J; Matteoli, G; Opdenakker, G; Thijs, G; Van Assche, G; Van Damme, J; Vermeire, S | 1 |
| Ahmetaj-Shala, B; Chang, TC; Chang, WL; Huang, SF; Lee, SY; Lin, JC; Tsai, WC | 1 |
| Alós, R; Barrachina, MD; Bernardo, D; Calatayud, S; Esplugues, JV; Gisbert-Ferrándiz, L; Hernández, C; Macías-Ceja, DC; Navarro-Vicente, F; Ortiz-Masiá, D; Salvador, P | 1 |
| Gao, C; Guo, Z; He, C; He, Q; Li, L; Li, Y; Pan, Y; Xiong, F; Yang, X | 1 |
| Fricker, M; Gellatly, SL; Goggins, BJ; Hansbro, PM; Jarnicki, AG; Jones, B; Keely, S; Kim, RY; Mateer, S; Oliver, BG; Powell, N; Radford-Smith, G; Talley, NJ; Walker, MM | 1 |
| Cheng, YY; Guo, Y; Ma, L; Qiao, L; Xu, CL | 1 |
| Barbosa, ALDR; da Silva Martins, C; de Aguiar Magalhãres, D; de Brito, TV; de Sousa de Almeida Leite, JR; Fernando Pereira Vasconcelos, D; Guimarães Sousa, S; José Dias Júnior, G; Maria Costa Véras, L; Oliveira Silva, R; Rodolfo Pereira da Silva, F; Rodrigues de Carvalho, L; Santos Martins, D; Simião da C Júnior, J; Soares de Oliveira, J | 1 |
| Bevivino, G; Colantoni, A; De Simone, V; Di Giovangiulio, M; Franzè, E; Izzo, R; Marafini, I; Monteleone, G; Monteleone, I; Ortenzi, A; Rizzo, A; Sedda, S | 1 |
| He, X; Huang, Q; Ke, J; Lan, P; Lian, L; Qin, H; Xie, M; Zhang, L | 1 |
| Chao, K; Chen, M; Ding, L; Feng, R; Feng, T; Hu, JF; Huang, S; Li, L; Qiu, Y; Wang, H; Zhang, S; Zhou, G | 1 |
| Cui, X; Li, M; Ni, Y; Shan, X; Shen, Y; Shen, Z; Wang, L; Wang, X; Wu, H; Zhang, D; Zhao, J; Zhou, G; Zhu, C | 1 |
| Hiraishi, K; Hu, YP; Inoue, R; Jian, YW; Koga, K; Kojima, D; Kurahara, LH; Onitsuka, M; Sumiyoshi, M; Takedatsu, H; Yue, L | 1 |
| Atreya, R; Baum, P; Carlé, B; Claussen, J; Ekici, AB; Friedrich, O; Kersten, C; Klimowicz, AC; Knieling, F; Kollias, G; Mbow, ML; Meyer, S; Neufert, C; Neurath, MF; Primbs, T; Rath, T; Raymond, EL; Scheibe, K; Schmied, A; Schürmann, S; Vieth, M; Waldner, MJ; Wirtz, S; Zheng, J | 1 |
| Bai, J; He, N; Tang, Q; Tian, Y; Wang, J; Wang, Y; Xue, B; Yang, L; Yu, J | 1 |
| Chen, T; Chen, YG; Jiang, F; Liu, Y; Shu, Y; Yang, BL; Zhang, D; Zhou, JY; Zhu, P | 1 |
| Bertin, B; Capron, M; Daniel, C; Dendooven, A; Deplanque, D; Desreumaux, P; Dubuquoy, L; Foligné, B; Neut, C; Pagny, A; Plé, C; Pottier, M; Singer, E; Standaert, A; Titécat, M | 1 |
| Du, H; Li, C; Li, S; Lou, X; Ning, L; Xu, G; Zhou, X; Zhu, H | 1 |
| Chen, H; Wen, Q; Zhang, Y; Zhou, L | 1 |
| Li, Q; Sarna, SK; Winston, JH | 1 |
| Hada, K; Hara, Y; Ishikawa, M; Ito, T; Iwamura, C; Maruyama, H; Masuda, D; Matsuo, T; Nakayama, T; Narita, M; Ogawa, Y; Ohno, Y; Sasaki, T; Takahashi, M; Tanaka, H; Tsuchiya, M; Yamashita, J | 1 |
| Chen, J; Dong, L; Huang, Z; Shi, H; Shi, S; Shi, T; Zeng, K; Zhang, C; Zhang, J; Zhao, R; Zhou, Q | 1 |
| Akbari, H; Flynn, RS; Grider, JR; Kellum, JM; Kuemmerle, JF; Li, C; Murthy, KS | 1 |
| Li, J; Shen, X; Sun, J; Wang, J; Zhao, G | 1 |
| Guan, YY; He, Q; Huang, LY; Liang, SJ; Liu, J; Lv, XF; Pang, RP; Su, YX; Tang, YB; Tao, J; Wang, JP; Wu, QQ; Wu, QY; Xiong, LX; Zhou, JG | 1 |
| Bugert, P; Büning, C; Chamaillard, M; Daniel, H; Goebel, U; Haller, D; Prager, M; Rath, E; Sartor, RB; Schaltenberg, N; Schulz, S; Ullrich, S; Witt, H; Wuensch, T | 1 |
| Bai, J; Ji, Q; Li, L; Ni, R; Qin, Y; Tang, Q; Xia, W | 1 |
| Gao, X; Hu, PJ; Li, CJ; Lu, Y; Yao, JY; Zhi, M | 1 |
| Chen, C; Cygankiewicz, AI; Fichna, J; Kordek, R; Krajewska, WM; Małecka-Panas, E; Mokrowiecka, A; Sałaga, M; Sobczak, M; Zakrzewski, PK | 1 |
| Chen, K; Saas, P; Sun, Y; Wang, H; Wang, S; Wang, Y; Xu, Y; Yuan, Y; Zhang, Y; Zhong, J | 1 |
| Bagyánszki, M; Berkó, A; Bódi, N; Fekete, É; Nagy, LI; Pál, A; Poles, MZ; Puskás, LG; Talapka, P | 1 |
| Adler, J; Dillman, JR; Higgins, PD; Johnson, LA; Moons, DS; Stidham, RW; Swanson, SD | 1 |
| Gong, C; Miao, X; Ni, R; Tang, Q; Wang, L; Xiao, M; Yan, L; Zhang, D | 1 |
| He, X; He, Z; Lan, P; Lian, L; Xie, M; Zhu, J | 1 |
| Chen, X; Cheng, X; Liang, H; Shi, R; Su, J; Wang, C; Zen, K; Zhang, CY; Zhang, H; Zhang, X; Zhang, Y; Zhou, J; Zhou, W | 1 |
| Bai, JA; Ji, QQ; Tang, QY; Wu, JD; Xu, GF; Yan, LJ; Zeng, WW | 1 |
| de Jonge, WJ; de Vries, CJ; Hamers, AA; Huveneers, S; Marinković, G; Meijer, SL; Te Velde, AA; Teixeira Duarte, JM; van Dam, L; van Stalborch, AM; van Tiel, CM; Vos, M | 1 |
| Abbasi, A; Dehpour, AR; Fakhfouri, G; Fakhraei, N; Ghia, JE; Heydarpour, P; Khoshkish, S; Rahimian, R; Salehi-Sadaghiani, M; Wang, H | 1 |
| Nyuyki, KD; Pittman, QJ | 1 |
| Cho, HK; Cho, SW; Choi, KC; Kook, SH; Lee, JC; Lee, KD | 1 |
| Azuma, YT; Fujimoto, Y; Ikeda, Y; Kuramoto, N; Kuwamura, M; Matsuo, Y; Nakajima, H; Nishiyama, K; Takeuchi, T; Yoshida, N | 1 |
| Gao, YJ; Huang, BX; Li, SN; Liu, DF; Liu, JX; Lv, QK; Lv, Y; Wang, W; Xu, SY; Xu, ZP; Yang, DX; Zeng, YL | 1 |
| Liu, TJ; Shi, YY; Wang, EB; Zhao, Q; Zhu, T | 1 |
| Caruso, R; Colantoni, A; Di Fusco, D; Dinallo, V; Franzè, E; Izzo, R; Marafini, I; Monteleone, G; Monteleone, I; Pallone, F; Zorzi, F | 1 |
| Feng, Q; He, Q; Li, L; Li, X; Li, Y; Liu, C; Su, L; Xia, Z; Xiao, L; Yan, T | 1 |
| Cai, Z; Fan, L; Huang, H; Jiang, Y; Lai, R; Li, J; Li, Z; Lin, W; Ma, C; Su, F; Sun, K; Wang, X; Zhang, T | 1 |
| Cao, R; Chen, J; Chen, W; Chen, Y; Feng, Y; Li, M; Ma, T; Ren, L; Shi, R; Zhang, H; Zhao, Y | 1 |
| Chao, K; Chen, B; Chen, M; Feng, R; He, Y; Li, M; Wang, H; Yu, Q; Zeng, Z; Zhang, S | 1 |
| Ferreirós, N; Gorkiewicz, G; Grill, M; Hasenoehrl, C; Heinemann, Á; Högenauer, C; Jandl, K; Labocha, S; Marsche, G; Radnai, B; Schicho, R; Stančić, A; Sturm, EM | 1 |
| Chen, Y; Fan, H; Fu, R; Jiang, C; Wang, H; Wang, Q; Yan, S; Zheng, X; Zhu, X | 1 |
| He, X; Lan, P; Lian, L; Luo, Q; Qin, H; Xie, M | 1 |
| Chen, L; Cui, X; Ding, H; Ji, Q; Li, M; Liu, Q; Ni, R; Qian, J; Shan, X; Wang, L; Wang, X; Zhang, D | 1 |
| Kuemmerle, JF | 1 |
| Bagyánszki, M; Berkó, A; Bódi, N; Chandrakumar, L; Fekete, É; Nagy, LI; Puskás, LG; Talapka, P | 1 |
| Feng, W; Haimin, C; Tingting, N; Wei, W; Xiaojun, Y; Xin, G; Zhanghe, Z | 1 |
| Filliettaz, C; Hsieh, H; LaBarre, S; Morin, J; Radi, Z; Varada, R | 1 |
| Du, J; Ge, X; Liu, L; Liu, T; Shi, Y; Teng, X; Wang, E; Zhao, Q | 1 |
| Atreya, R; Garn, H; Gerlach, K; Ho, IC; Lehr, HA; Mott, S; Neurath, MF; Popp, V; Renz, H; Turowska, A; Weigmann, B | 1 |
| Crosier, KE; Crosier, PS; Flores, MV; Hall, CJ; Ko, DC; Oehlers, SH; Wang, L | 1 |
| Chen, J; Fu, Y; Huang, Z; Ma, J; Ma, Z; Shi, T; Xie, Y; Zhang, J; Zhou, Q | 1 |
| Aziz, M; Bohn, P; Guérin, C; Marion-Letellier, R; Modzelewski, R; Savoye, G; Savoye-Collet, C; Vera, P | 1 |
| Hao, ZM; Li, Q; Li, S; Lv, YF; Zhang, QN; Zhang, XT; Zheng, XY | 1 |
| Lee, JA; Renshaw, SA | 1 |
| Bai, J; Bai, W; Li, Y; Shi, R; Tian, D | 1 |
| Chmielowiec-Korzeniowska, A; Fichna, J; Kordek, R; Siczek, K; Tymczyna, L; Zatorski, H | 1 |
| Cai, TT; Chen, T; Shen, Y; Sun, Y; Xu, Q; Zhou, XB | 1 |
| Guan, Q; Hillman, CL; Ma, A; Ma, Y; Peng, Z; Qing, G; Zhou, G | 1 |
| Distrutti, E; Fiorucci, S; Mencarelli, A; Renga, B; Vavassori, P | 1 |
| Bonkowski, E; D'Mello, S; Denson, LA; Divanovic, S; Flick, L; Han, X; Jurickova, II; Karp, CL; Kugathasan, S; Pasternak, BA; Petiniot, L; Traurnicht, A; Uozumi, N; Willson, T | 1 |
| Fitzpatrick, LR; Green, CL; Maines, LW; Smith, CD; Zhuang, Y | 1 |
| Chelbi-Alix, MK; Singer, M; Trugnan, G | 1 |
| Sarna, SK; Shi, XZ; Winston, JH | 1 |
| Chisato, N; Hira, Y; Kaneko, A; Kono, T; Miura, N; Ohtake, N; Suzuki, T; Watanabe, T | 1 |
| Azevedo, V; Bermúdez-Humarán, LG; de Moreno de LeBlanc, A; del Carmen, S; Langella, P; LeBlanc, JG; Miyoshi, A; Perdigon, G; Sesma, F; Watterlot, L | 1 |
| Blum-Sperisen, S; Heupel, E; Philippe, D; Riedel, CU | 1 |
| Benson, EL; Heuvelman, DM; Masferrer, JL; Radi, ZA | 1 |
| Cárdeno, A; de la Lastra, CA; Rosillo, MA; Sanchez-Hidalgo, M | 1 |
| Higgins, PD; Johnson, LA; Kim, K; McKenna, BJ; Moons, DS; Rubin, JM; Stidham, RW; Xu, J | 1 |
| Chiba, S; Hira, Y; Kaneko, A; Kono, T; Noguchi, M; Omiya, Y; Suzuki, T; Watanabe, T | 1 |
| Gillespie, BW; Govani, SM; Higgins, PD; Johnson, LA; Joyce, JC; Waljee, AK | 1 |
| Jing, S; Sheng, YH; Wang, XY; Yan, X; Yang, S; Yang, X | 1 |
| Coutinho-Netto, J; Epifânio, VL; Foss, NT; Lachat, JJ; Teixeira, LB | 1 |
| Aparicio-Soto, M; Cárdeno, A; de la Lastra, CA; Rosillo, MA; Sánchez-Fidalgo, S; Sánchez-Hidalgo, M; Villegas, I | 1 |
| Casagrande, V; Cavalera, M; Federici, M; Franzè, E; Lauro, R; MacDonald, TT; Monteleone, G; Monteleone, I; Pallone, F; Rizzo, A; Sarra, M; Zorzi, F | 1 |
| Aranda, CJ; de Medina, FS; González, R; Hernández-Chirlaque, C; Marín, JJ; Martínez-Augustin, O; Martínez-Moya, P; Requena, P; Romero-Calvo, I; Suárez, MD; Zarzuelo, A | 1 |
| Abad, C; Arranz, A; Delgado, M; Gomariz, RP; Juarranz, MG; Leceta, J; Martinez, C | 1 |
| Bourreille, A; Cario-Toumaniantz, C; Galmiche, JP; Hilaret, G; Loirand, G; Pacaud, P; Raingeard de la Blétière, D; Sauzeau, V; Segain, JP | 1 |
| Bourreille, A; Buelow, R; de la Blétière, DR; Doubremelle, M; Galmiche, JP; Segain, JP; Toquet, C | 1 |
| De Man, JG; De Winter, BY; Herman, AG; Moreels, TG; Nieuwendijk, RJ; Pelckmans, PA; Van Marck, EA | 1 |
| Abken, H; Hombach, A; Marth, T; Neurath, M; Schmidt, C; Stallmach, A; Weiss, B; Wittig, BM; Zeitz, M; Zeuzem, S | 1 |
| Bryndová, J; Kment, M; Pácha, J; Zbánková, S | 1 |
| Fankhaenel, S; Gao, D; Hecker, M; Panzner, S; Schweyer, S; Stojanovic, T; Wagner, AH | 1 |
| Aharoni, R; Arnon, R; Kayhan, B | 1 |
| Hollenbach, E; Malfertheiner, P; Naumann, M; Neumann, M; Roessner, A; Vieth, M | 1 |
| Abad, C; Arranz, A; García-Gómez, M; Gomariz, RP; Juarranz, Y; Leceta, J; Martinez, C; Rosignoli, F | 1 |
| Ouyang, Q; Wang, X | 1 |
| Azooz, O; Ballinger, AB; Croft, NM; Idestrom, M; Paraszczuk, J; Sanderson, IR; Savage, MO; Sawczenko, A | 1 |
| Arisawa, T; Hori, M; Imakawa, K; Ina, K; Isuzugawa, K; Iwata, M; Murase, Y; Murata, T; Nakano, H; Nishimura, N; Ohta, M; Ozaki, H; Takahashi, Y; Yamamoto, S; Yamato, S | 1 |
| Chorny, A; Delgado, M; Fernandez-Martin, A; Gonzalez-Rey, E | 1 |
| Bennink, RJ; Hommes, DW; Koehler, TC; Peppelenbosch, MP; te Velde, AA; ten Cate, FJ; Van den Brande, JM; van Deventer, SJ; Zelinkova, Z | 1 |
| Benight, N; Denson, LA; Frank, SJ; Han, X; Loesch, K; Osuntokun, B | 1 |
| Bailón, E; Camuesco, D; Comalada, M; Concha, A; Fernández de Arriba, A; Gálvez, J; Merlos, M; Nieto, A; Ramis, I; Román, J; Zarzuelo, A | 1 |
| Appelbee, A; Forrest, CH; Jooste, JC; Klopcic, B; Lawrance, IC; Lloyd, F; Raye, W | 1 |
| Asano, N; Fuss, IJ; Kitani, A; Murray, PJ; Ozato, K; Strober, W; Tailor, P; Watanabe, T | 1 |
| Ando, Y; Ikehara, S; Inaba, M; Okazaki, K; Omae, M; Quan, GK; Sakaguchi, Y; Tsuda, M | 1 |
| Higgins, PD; Jia, C; Johnson, LA; Joyce, JC; Kim, K; Rangwalla, S; Rubin, JM | 1 |
| Caprilli, R; Catitti, V; D'Angelo, A; Gaudio, E; Latella, G; Sferra, R; Vetuschi, A; Zanninelli, G | 1 |
| Brand, S; Buckley, NE; Emmerdinger, D; Göke, B; Keenan, CM; Lutz, B; Massa, F; Patel, KD; Sharkey, KA; Sibaev, A; Storr, MA; Yüce, B; Zhang, H | 1 |
| Anthony, D; Boulos, P; Sams, V; Savage, F | 1 |
| Fuss, I; Kelsall, BL; Neurath, MF; Strober, W; Stüber, E | 1 |
| Hibi, T; Inoue, N; Ishii, H; Iwao, Y; Takaishi, H; Ueno, Y; Watanabe, M; Yajima, T | 1 |
| Matsueda, K; Shoda, R; Umeda, N; Yamato, S | 1 |
| Duchmann, R; Knolle, P; Meyer zum Büschenfelde, KH; Neurath, M; Schmitt, E | 1 |
| Meyer zum Büschenfelde, KH; Neurath, MF; Pettersson, S; Strober, W | 1 |
| Muto, T; Saito, H; Shinozaki, M | 1 |
| Macdonald, TT | 1 |
| Hamada, Y; Hibi, T; Hosoda, Y; Inoue, N; Ishii, H; Iwao, Y; Okamoto, S; Suzuki, T; Ueno, Y; Watanabe, M; Watanabe, N; Yamada, T; Yamazaki, M | 1 |
| Antolín, M; Crespo, E; García-Lafuente, A; González, G; Guarner, F; Malagelada, JR; Salas, A; Videla, S; Vilaseca, J | 1 |
| Fuss, I; Neurath, M; Strober, W | 1 |
| Galinkin, D; Mullin, GE | 1 |
| Arseneau, KO; Brazer, W; Castagliuolo, I; Cruickshank, WW; Keates, AC; Kelly, CP; Qiu, B | 1 |
| Akira, S; Hibi, T; Iiyama, R; Ikeda, M; Ishii, H; Kanai, T; Kurimoto, M; Okamoto, R; Okamoto, S; Okazawa, A; Sato, T; Takeda, K; Totsuka, T; Watanabe, M; Yamazaki, M | 1 |
| Camoglio, L; Juffermans, NP; Kopf, M; Peppelenbosch, M; te Velde, AA; ten Kate, FJ; van Deventer, SJ | 1 |
| Aoki, Y; Fukumoto, Y; Hamamura, I; Hase, N; Kamimura, T; Kaneko, H; Kasai, H; Katsuura, Y; Kobayashi, T; Komoriya, K; Ota, M; Sugiyama, H; Takahashi, H | 1 |
| Asaka, M; Hige, S; Iwanaga, T; Kato, M; Mizue, Y; Nakamura, H; Nishihira, J; Ohkawara, T; Sugiyama, T; Takeda, H | 1 |
| Guarner, F; Malagelada, JR; Martínez, M; Rodríguez, R; Salas, A; Vilaseca, J | 1 |
3 review(s) available for trinitrobenzenesulfonic acid and Crohn Disease
| Article | Year |
|---|---|
Beneficial effects of nutritional supplements on intestinal epithelial barrier functions in experimental colitis models
Topics: Animals; Caco-2 Cells; Colitis, Ulcerative; Crohn Disease; Dextran Sulfate; Dietary Supplements; Disease Models, Animal; Drug Evaluation, Preclinical; Fatty Acids; Humans; Intestinal Absorption; Intestinal Mucosa; Oxidative Stress; Permeability; Phytochemicals; Tight Junctions; Treatment Outcome; Trinitrobenzenesulfonic Acid; Vitamins | 2019 |
Toward a better understanding of the central consequences of intestinal inflammation.
Topics: Animals; Colitis, Ulcerative; Colon; Crohn Disease; Disease Models, Animal; Humans; Inflammation; Rats; Receptors, AMPA; Trinitrobenzenesulfonic Acid | 2015 |
TNBS-colitis.
Topics: Animals; Colitis; Crohn Disease; Disease Models, Animal; Humans; Trinitrobenzenesulfonic Acid | 2000 |
4 trial(s) available for trinitrobenzenesulfonic acid and Crohn Disease
| Article | Year |
|---|---|
Contribution of the Gut Microbiota in P28GST-Mediated Anti-Inflammatory Effects: Experimental and Clinical Insights.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Colitis; Crohn Disease; Fecal Microbiota Transplantation; Feces; Female; Gastrointestinal Microbiome; Glutathione Transferase; Humans; Immunization; Immunomodulation; Mice, Inbred BALB C; Phenotype; Trinitrobenzenesulfonic Acid | 2019 |
Rho kinase blockade prevents inflammation via nuclear factor kappa B inhibition: evidence in Crohn's disease and experimental colitis.
Topics: Adolescent; Adult; Aged; Amides; Animals; Cells, Cultured; Colitis; Crohn Disease; Cytokines; Enzyme Inhibitors; Female; Humans; I-kappa B Kinase; Intestinal Mucosa; Intracellular Signaling Peptides and Proteins; Leukocytes, Mononuclear; Male; Middle Aged; NF-kappa B; Prospective Studies; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; rhoA GTP-Binding Protein; Trinitrobenzenesulfonic Acid | 2003 |
RDP58, a novel immunomodulatory peptide with anti-inflammatory effects. A pharmacological study in trinitrobenzene sulphonic acid colitis and Crohn disease.
Topics: Adolescent; Adult; Aged; Animals; Anti-Inflammatory Agents; Colitis; Crohn Disease; Female; Histocompatibility Antigens Class I; Humans; Interferon-gamma; Interleukin-1; Intestinal Mucosa; Male; Middle Aged; Models, Animal; Peptides; Prospective Studies; Rats; Rats, Sprague-Dawley; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha | 2003 |
Prediction of antitumour necrosis factor clinical efficacy by real-time visualisation of apoptosis in patients with Crohn's disease.
Topics: Adult; Animals; Annexin A5; Antibodies, Monoclonal; Apoptosis; CD4-Positive T-Lymphocytes; Colitis; Crohn Disease; Disease Models, Animal; Female; Gastrointestinal Agents; Humans; Infliximab; Intestinal Mucosa; Male; Mice; Mice, Inbred BALB C; Mice, SCID; Middle Aged; Organotechnetium Compounds; Severity of Illness Index; Tomography, Emission-Computed, Single-Photon; Treatment Outcome; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha | 2007 |
144 other study(ies) available for trinitrobenzenesulfonic acid and Crohn Disease
| Article | Year |
|---|---|
Colonic inflammation induces changes in glucose levels through modulation of incretin system.
Topics: Adult; Animals; Blood Glucose; Case-Control Studies; Colitis; Crohn Disease; Dipeptidyl Peptidase 4; Disease Models, Animal; Female; Glucagon-Like Peptide 1; Humans; Incretins; Inflammation; Male; Mice; Mice, Inbred C57BL; Middle Aged; Proprotein Convertase 1; Trinitrobenzenesulfonic Acid; Young Adult | 2021 |
Olaparib: A Clinically Applied PARP Inhibitor Protects from Experimental Crohn's Disease and Maintains Barrier Integrity by Improving Bioenergetics through Rescuing Glycolysis in Colonic Epithelial Cells.
Topics: Animals; Colitis; Colon; Crohn Disease; Energy Metabolism; Epithelial Cells; Glycolysis; Male; Mice; Oxidative Stress; Permeability; Phthalazines; Piperazines; Poly(ADP-ribose) Polymerase Inhibitors; Trinitrobenzenesulfonic Acid | 2021 |
Hypermethylation of miR-145 promoter-mediated SOX9-CLDN8 pathway regulates intestinal mucosal barrier in Crohn's disease.
Topics: Animals; Claudins; Crohn Disease; Humans; Intestinal Mucosa; Mice; MicroRNAs; SOX9 Transcription Factor; Trinitrobenzenesulfonic Acid | 2022 |
A TNBS-Induced Rodent Model to Study the Pathogenic Role of Mechanical Stress in Crohn's Disease.
Topics: Animals; Colitis; Colon; Crohn Disease; Disease Models, Animal; Rats; Rats, Sprague-Dawley; Rodentia; Stress, Mechanical; Trinitrobenzenesulfonic Acid | 2022 |
Peptide YY 3-36 attenuates trinitrobenzene sulfonic acid-induced colitis in mice by modulating Th1/Th2 differentiation.
Topics: Animals; Colitis; Crohn Disease; Cytokines; Disease Models, Animal; Interleukin-6; Mice; Mice, Inbred BALB C; Peptide YY; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha | 2022 |
MFE40-the active fraction of Mume Fructus alcohol extract-alleviates Crohn's disease and its complications.
Topics: Animals; Citrates; Colon; Crohn Disease; Cytokines; Disease Models, Animal; Ethanol; Inflammation; Interleukin-17; Interleukin-6; Intestinal Obstruction; Lipopolysaccharides; Lung Injury; Occludin; Rats; RNA, Ribosomal, 16S; Trinitrobenzenesulfonic Acid | 2022 |
Olmesartan medoxomil self-microemulsifying drug delivery system reverses apoptosis and improves cell adhesion in trinitrobenzene sulfonic acid-induced colitis in rats.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cadherins; Caspase 3; Cell Adhesion; Colitis; Crohn Disease; Drug Delivery Systems; Interleukin-6; Malondialdehyde; Matrix Metalloproteinase 9; Olmesartan Medoxomil; Peroxidase; Rats; Sulfasalazine; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha | 2022 |
Elafin Reverses Intestinal Fibrosis by Inhibiting Cathepsin S-Mediated Protease-Activated Receptor 2.
Topics: Animals; Cathepsins; Collagen; Constriction, Pathologic; Crohn Disease; Elafin; Fibrosis; Humans; Intestinal Obstruction; Intestines; Mice; Peptide Hydrolases; Polymethacrylic Acids; Protease Inhibitors; Proteome; Receptor, PAR-2; Trinitrobenzenesulfonic Acid; Zinc Finger E-box-Binding Homeobox 1 | 2022 |
Human umbilical cord-derived mesenchymal stem cells ameliorate experimental colitis by normalizing the gut microbiota.
Topics: Animals; Colitis; Crohn Disease; Disease Models, Animal; Dysbiosis; Gastrointestinal Microbiome; Humans; Mesenchymal Stem Cells; Mice; RNA, Ribosomal, 16S; Trinitrobenzenesulfonic Acid; Umbilical Cord | 2022 |
Inflammation-induced Occludin Downregulation Limits Epithelial Apoptosis by Suppressing Caspase-3 Expression.
Topics: Animals; Apoptosis; Caco-2 Cells; Case-Control Studies; Caspase 3; Colitis; Colitis, Ulcerative; Colon; Crohn Disease; Dextran Sulfate; Disease Models, Animal; Epithelial Cells; Humans; Intestinal Mucosa; Mice, Inbred C57BL; Mice, Knockout; Occludin; Signal Transduction; Trinitrobenzenesulfonic Acid; Zonula Occludens-1 Protein | 2019 |
Mechanistic Insight into the Development of TNBS-Mediated Intestinal Fibrosis and Evaluating the Inhibitory Effects of Rapamycin.
Topics: Animals; Colitis; Crohn Disease; Disease Models, Animal; Intestinal Mucosa; Intestines; Mice; Sirolimus; Trinitrobenzenesulfonic Acid | 2019 |
Preclinical Model of Perianal Fistulizing Crohn's Disease.
Topics: Anal Canal; Animals; Crohn Disease; Disease Models, Animal; Proctitis; Rats; Rectal Fistula; Reproducibility of Results; Trinitrobenzenesulfonic Acid | 2020 |
Nod2 Protects the Gut From Experimental Colitis Spreading to Small Intestine.
Topics: Animals; Cecum; Colitis; Crohn Disease; Duodenitis; Duodenum; Gene Expression; Humans; Ileitis; Ileum; Interferon-gamma; Interleukin-12; Intestinal Mucosa; Mice; Mice, Knockout; Nod2 Signaling Adaptor Protein; RNA, Messenger; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha | 2020 |
Role of Interleukin-17 in Pathogenesis of Intestinal Fibrosis in Mice.
Topics: Animals; Collagen Type III; Crohn Disease; Disease Models, Animal; Female; Fibrosis; Immunoglobulin G; Interleukin-17; Interleukin-1beta; Intestinal Mucosa; Intestines; Matrix Metalloproteinase 2; Mice; Reverse Transcriptase Polymerase Chain Reaction; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta1; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha; Up-Regulation | 2020 |
lncRNACNN3-206 activates intestinal epithelial cell apoptosis and invasion by sponging miR-212, an implication for Crohn's disease.
Topics: 3' Untranslated Regions; Adolescent; Adult; Animals; Apoptosis; Caco-2 Cells; Caspase 10; Cell Movement; Crohn Disease; Disease Models, Animal; Epithelial Cells; Female; Gene Expression Profiling; Gene Knockdown Techniques; HT29 Cells; Humans; Intestinal Mucosa; Male; Mice; MicroRNAs; Middle Aged; RNA, Long Noncoding; RNA, Small Interfering; Tissue Array Analysis; Trinitrobenzenesulfonic Acid; Young Adult | 2020 |
miR-802 participates in the inflammatory process of inflammatory bowel disease by suppressing SOCS5.
Topics: Adult; Animals; Case-Control Studies; CD4-Positive T-Lymphocytes; Cell Differentiation; Cells, Cultured; Colitis, Ulcerative; Colon; Crohn Disease; Disease Models, Animal; Female; Healthy Volunteers; Humans; Interleukin-17; Intestinal Mucosa; Male; Mice; MicroRNAs; Primary Cell Culture; Suppressor of Cytokine Signaling Proteins; Th17 Cells; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha; Up-Regulation | 2020 |
Evaluation of protein arginine deiminase-4 inhibitor in TNBS- induced colitis in mice.
Topics: Animals; Anti-Inflammatory Agents; Colitis; Colon; Crohn Disease; Cytokines; Disease Models, Animal; Extracellular Traps; Female; Mice, Inbred BALB C; Ornithine; Protein-Arginine Deiminase Type 4; Trinitrobenzenesulfonic Acid | 2020 |
M2 Macrophages and Phenotypic Modulation of Intestinal Smooth Muscle Cells Characterize Inflammatory Stricture Formation in Rats.
Topics: Animals; Constriction, Pathologic; Crohn Disease; Hyperplasia; Intestines; Macrophages; Muscle, Smooth; Myocytes, Smooth Muscle; Phenotype; Rats; Rats, Sprague-Dawley; Trinitrobenzenesulfonic Acid | 2020 |
Polyphenolic Maqui Extract as a Potential Nutraceutical to Treat TNBS-Induced Crohn's Disease by the Regulation of Antioxidant and Anti-Inflammatory Pathways.
Topics: Acute-Phase Reaction; Administration, Oral; Animals; Anti-Inflammatory Agents; Antioxidants; Crohn Disease; Cyclooxygenase 2; Dietary Supplements; Disease Models, Animal; Fruit; Heme Oxygenase-1; Inflammation Mediators; Male; Membrane Proteins; Mice, Inbred BALB C; NF-E2-Related Factor 2; Nitric Oxide Synthase Type II; Nutritional Physiological Phenomena; Phytotherapy; Polyphenols; Signal Transduction; Trinitrobenzenesulfonic Acid | 2020 |
Effect of recombinant serine protease from adult stage of Trichinella spiralis on TNBS-induced experimental colitis in mice.
Topics: Aging; Animals; Colitis; Colon; Crohn Disease; Cytokines; Disease Models, Animal; Female; Helminth Proteins; Mice, Inbred BALB C; Recombinant Proteins; Serine Proteases; Spleen; T-Lymphocytes, Regulatory; Th1 Cells; Th17 Cells; Th2 Cells; Trichinella spiralis; Trinitrobenzenesulfonic Acid | 2020 |
Translational research into the effects of cigarette smoke on inflammatory mediators and epithelial TRPV1 in Crohn's disease.
Topics: Adult; Aged; Animals; Caco-2 Cells; Colon; Crohn Disease; Cytokines; Disease Models, Animal; Female; HT29 Cells; Humans; Ileum; Inflammation; Intestinal Mucosa; Male; Mice; Mice, Inbred C57BL; Middle Aged; Tobacco Smoking; Translational Research, Biomedical; Trinitrobenzenesulfonic Acid; TRPV Cation Channels | 2020 |
miR-130a-3p, a Preclinical Therapeutic Target for Crohn's Disease.
Topics: Animals; Biomarkers; Colonoscopy; Crohn Disease; Female; Humans; Male; Mice; Mice, Inbred BALB C; Microarray Analysis; MicroRNAs; Middle Aged; Prospective Studies; RNA, Messenger; Signal Transduction; Trinitrobenzenesulfonic Acid | 2021 |
Gasdermin-E-mediated pyroptosis participates in the pathogenesis of Crohn's disease by promoting intestinal inflammation.
Topics: Animals; Colitis; Crohn Disease; Epithelial Cells; Hematopoiesis; HMGB1 Protein; Humans; Inflammation; Intestinal Mucosa; Intestines; Male; Mice, Inbred C57BL; Pore Forming Cytotoxic Proteins; Pyroptosis; Severity of Illness Index; Trinitrobenzenesulfonic Acid | 2021 |
Ferrostatin-1 alleviated TNBS induced colitis via the inhibition of ferroptosis.
Topics: Animals; Colitis, Ulcerative; Crohn Disease; Cyclohexylamines; Female; Ferroptosis; Humans; Immunosuppressive Agents; Mice; Mice, Inbred BALB C; Phenylenediamines; Trinitrobenzenesulfonic Acid | 2021 |
PRDM5 promotes the apoptosis of epithelial cells induced by IFN-γ during Crohn's disease.
Topics: Animals; Apoptosis; Caspase 3; Cell Line; Colitis; Crohn Disease; Disease Models, Animal; DNA-Binding Proteins; Epithelial Cells; Humans; Interferon-gamma; Intestinal Mucosa; Intestines; Mice; Transcription Factors; Trinitrobenzenesulfonic Acid; Up-Regulation | 2017 |
Inhibition of gelatinase B/MMP-9 does not attenuate colitis in murine models of inflammatory bowel disease.
Topics: Animals; Colitis, Ulcerative; Colon; Crohn Disease; Dextran Sulfate; Disease Models, Animal; Female; Gastrointestinal Agents; Humans; Male; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred C57BL; Mice, Knockout; Treatment Outcome; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha; Up-Regulation | 2017 |
Astragaloside II promotes intestinal epithelial repair by enhancing L-arginine uptake and activating the mTOR pathway.
Topics: Animals; Arginine; Caco-2 Cells; Cell Proliferation; Colitis; Crohn Disease; Humans; Intestinal Mucosa; Male; Mice; Mice, Inbred C57BL; Saponins; Signal Transduction; TOR Serine-Threonine Kinases; Treatment Outcome; Trinitrobenzenesulfonic Acid; Wound Healing | 2017 |
CD16+ Macrophages Mediate Fibrosis in Inflammatory Bowel Disease.
Topics: Adolescent; Adult; Animals; Cell Count; Cells, Cultured; Colitis; Colon; Colonic Neoplasms; Crohn Disease; Female; Fibrosis; Humans; Interleukin-4; Intestinal Mucosa; Lectins, C-Type; Macrophages; Male; Mannose Receptor; Mannose-Binding Lectins; Mice; Mice, Inbred BALB C; Mice, Knockout; Proto-Oncogene Proteins; Receptors, Cell Surface; Receptors, IgG; STAT6 Transcription Factor; Trinitrobenzenesulfonic Acid; Wnt Proteins; Young Adult | 2018 |
MicroRNA-425 facilitates pathogenic Th17 cell differentiation by targeting forkhead box O1 (Foxo1) and is associated with inflammatory bowel disease.
Topics: Animals; Antagomirs; Case-Control Studies; Cell Differentiation; Cell Proliferation; Colitis; Colitis, Ulcerative; Crohn Disease; Forkhead Box Protein O1; Gene Expression Regulation; Humans; Interleukin-17; Intestinal Mucosa; Leukocytes, Mononuclear; Mice; Mice, Inbred BALB C; MicroRNAs; RNA, Small Interfering; Severity of Illness Index; Signal Transduction; Th17 Cells; Trinitrobenzenesulfonic Acid | 2018 |
Chronic cigarette smoke exposure induces systemic hypoxia that drives intestinal dysfunction.
Topics: Adult; Aged; Amino Acids, Dicarboxylic; Animals; Biopsy; Cell Hypoxia; Colon; Colonoscopy; Crohn Disease; Disease Models, Animal; Disease Progression; Female; Humans; Ileum; Intestinal Mucosa; Lung; Male; Mice; Mice, Inbred C57BL; Middle Aged; Nicotiana; Oxidative Stress; Prolyl Hydroxylases; Prolyl-Hydroxylase Inhibitors; Pulmonary Disease, Chronic Obstructive; Pulmonary Gas Exchange; Risk Factors; Smoke; Smoking; Smoking Cessation; Time Factors; Trinitrobenzenesulfonic Acid | 2018 |
Recombinant expressed vasoactive intestinal peptide analogue ameliorates TNBS-induced colitis in rats.
Topics: Animals; Colon; Crohn Disease; Diarrhea; Disease Models, Animal; Gastrointestinal Agents; Humans; Intestinal Mucosa; Male; Necrosis; NF-kappa B; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Signal Transduction; Toll-Like Receptor 4; Treatment Outcome; Trinitrobenzenesulfonic Acid; Vasoactive Intestinal Peptide | 2018 |
Epiisopiloturine, an imidazole alkaloid, reverses inflammation and lipid peroxidation parameters in the Crohn disease model induced by trinitrobenzenosulfonic acid in Wistar rats.
Topics: 4-Butyrolactone; Alkaloids; Animals; Anti-Inflammatory Agents; Crohn Disease; Disease Models, Animal; Female; Imidazoles; Inflammation; Intestinal Mucosa; Lipid Peroxidation; Rats, Wistar; Trinitrobenzenesulfonic Acid | 2018 |
Knockdown of Smad7 With a Specific Antisense Oligonucleotide Attenuates Colitis and Colitis-Driven Colonic Fibrosis in Mice.
Topics: Animals; Colitis; Collagen Type I; Colon; Crohn Disease; Disease Models, Animal; Down-Regulation; Female; Fibrosis; Gene Knockdown Techniques; Mice; Mice, Inbred BALB C; Oligonucleotides; Oligonucleotides, Antisense; Signal Transduction; Smad3 Protein; Smad7 Protein; Transforming Growth Factor beta1; Trinitrobenzenesulfonic Acid | 2018 |
Anti-fibrogenic Potential of Mesenchymal Stromal Cells in Treating Fibrosis in Crohn's Disease.
Topics: Animals; Cells, Cultured; Colon; Crohn Disease; Disease Models, Animal; Epithelial-Mesenchymal Transition; Fibrosis; Gene Expression Regulation; Interleukins; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice, Inbred BALB C; Phenotype; Phosphorylation; Signal Transduction; Smad2 Protein; Smad3 Protein; Stem Cell Niche; Time Factors; Transforming Growth Factor beta; Trinitrobenzenesulfonic Acid | 2018 |
Cytokine IL9 Triggers the Pathogenesis of Inflammatory Bowel Disease Through the miR21-CLDN8 Pathway.
Topics: Animals; Caco-2 Cells; Case-Control Studies; Claudins; Colitis; Crohn Disease; Follow-Up Studies; Humans; Interleukin-9; Male; Mice; Mice, Inbred BALB C; MicroRNAs; Trinitrobenzenesulfonic Acid | 2018 |
FKBP11 protects intestinal epithelial cells against inflammation‑induced apoptosis via the JNK‑caspase pathway in Crohn's disease.
Topics: Animals; Apoptosis; Caspases; Colitis; Crohn Disease; Endoplasmic Reticulum Stress; Epithelial Cells; Gene Expression Regulation; Humans; Inflammation; Interferon-gamma; Intestinal Mucosa; MAP Kinase Kinase 4; Mice; RNA, Small Interfering; Signal Transduction; Tacrolimus Binding Proteins; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha | 2018 |
Daikenchuto (Da-Jian-Zhong-Tang) ameliorates intestinal fibrosis by activating myofibroblast transient receptor potential ankyrin 1 channel.
Topics: Adult; Animals; Cell Line; Chronic Disease; Colitis; Colon; Crohn Disease; Disease Models, Animal; Fibrosis; Humans; Male; Mice; Mice, Knockout; Middle Aged; Myofibroblasts; Panax; Plant Extracts; Trinitrobenzenesulfonic Acid; TRPA1 Cation Channel; Zanthoxylum; Zingiberaceae | 2018 |
Inhibiting Interleukin 36 Receptor Signaling Reduces Fibrosis in Mice With Chronic Intestinal Inflammation.
Topics: Actins; Animals; Antibodies, Neutralizing; Case-Control Studies; Cells, Cultured; Colitis; Colitis, Ulcerative; Collagen Type VI; Colon; Crohn Disease; Dextran Sulfate; Fibroblasts; Fibrosis; Gene Expression; Gene Expression Profiling; Humans; Interleukin-1; Intestinal Mucosa; Intestine, Small; Ligands; Mice; Mice, Knockout; Receptors, Interleukin-1; Signal Transduction; Transcriptome; Trinitrobenzenesulfonic Acid | 2019 |
DNA Methylation of miR-122 Aggravates Oxidative Stress in Colitis Targeting SELENBP1 Partially by p65NF-
Topics: Animals; Base Sequence; Colitis; Crohn Disease; DNA Methylation; Down-Regulation; HT29 Cells; Humans; Hydrogen Peroxide; Mice; MicroRNAs; Oxidative Stress; Selenium-Binding Proteins; Signal Transduction; Trinitrobenzenesulfonic Acid | 2019 |
Total flavone of Abelmoschus manihot ameliorates Crohn's disease by regulating the NF‑κB and MAPK signaling pathways.
Topics: Abelmoschus; Animals; Colon; Crohn Disease; Flavones; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; NF-kappa B; RAW 264.7 Cells; Trinitrobenzenesulfonic Acid | 2019 |
EZH2 Regulates Intestinal Inflammation and Necroptosis Through the JNK Signaling Pathway in Intestinal Epithelial Cells.
Topics: Animals; Caco-2 Cells; Chemokine CCL20; Chemokine CCL5; Colitis; Colitis, Ulcerative; Crohn Disease; Dextran Sulfate; Down-Regulation; Enhancer of Zeste Homolog 2 Protein; Gene Knockdown Techniques; Humans; In Vitro Techniques; Inflammation; Inflammatory Bowel Diseases; Interleukin-17; Interleukin-8; Intestinal Mucosa; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mice; Necroptosis; Nuclear Pore Complex Proteins; Phosphoproteins; Proto-Oncogene Proteins c-jun; Real-Time Polymerase Chain Reaction; Receptor-Interacting Protein Serine-Threonine Kinases; RNA-Binding Proteins; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha | 2019 |
N-(3', 4'-dimethoxycinnamonyl) anthranilic acid alleviated experimental colitis by inhibiting autoimmune response and inducing CD4+ CD25+ regulatory T cells production.
Topics: Adult; Animals; Autoimmunity; CD4 Antigens; Cells, Cultured; Colitis; Crohn Disease; Cytokines; Female; Humans; Interleukin-2 Receptor alpha Subunit; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mucous Membrane; ortho-Aminobenzoates; T-Lymphocytes, Regulatory; Th1 Cells; Th2 Cells; Trinitrobenzenesulfonic Acid | 2013 |
Paradoxical regulation of ChAT and nNOS expression in animal models of Crohn's colitis and ulcerative colitis.
Topics: Acetylcholine; Animals; Blotting, Western; Choline O-Acetyltransferase; Colitis, Ulcerative; Colon; Crohn Disease; Cytokines; Dextran Sulfate; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Hydrogen Peroxide; Inflammation Mediators; Leupeptins; Male; Myenteric Plexus; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type I; Protein Multimerization; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Trinitrobenzenesulfonic Acid; Ubiquitin Thiolesterase | 2013 |
Paraoxonase-1 suppresses experimental colitis via the inhibition of IFN-γ production from CD4 T cells.
Topics: Active Transport, Cell Nucleus; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Aryldialkylphosphatase; CD4-Positive T-Lymphocytes; Cell Differentiation; Cell Line; CHO Cells; Colitis; Colon; Cricetinae; Crohn Disease; Female; Humans; Interferon-gamma; Male; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mice, SCID; NF-kappa B; Th1 Cells; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha | 2013 |
miR-141 Regulates colonic leukocytic trafficking by targeting CXCL12β during murine colitis and human Crohn's disease.
Topics: Animals; Cell Movement; Cells, Cultured; Chemokine CXCL12; Colitis; Colon; Crohn Disease; Down-Regulation; Epithelial Cells; Female; Gene Expression Regulation; Humans; Interleukin-10; Mice; Mice, Inbred BALB C; Mice, Knockout; MicroRNAs; RNA, Messenger; Trinitrobenzenesulfonic Acid | 2014 |
Increased activation of latent TGF-β1 by αVβ3 in human Crohn's disease and fibrosis in TNBS colitis can be prevented by cilengitide.
Topics: Adult; Animals; Blotting, Western; Cells, Cultured; Colon; Crohn Disease; Cytokines; Enzyme-Linked Immunosorbent Assay; Female; Fibrosis; Fluorescent Antibody Technique; Humans; Integrin alphaVbeta3; Intestinal Mucosa; Intestines; Male; Middle Aged; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Snake Venoms; Transforming Growth Factor beta1; Trinitrobenzenesulfonic Acid; Young Adult | 2013 |
Aquaporin 3 and 8 are down-regulated in TNBS-induced rat colitis.
Topics: Animals; Aquaporin 3; Aquaporins; Colon; Crohn Disease; Disease Models, Animal; Down-Regulation; Female; Rats; Rats, Sprague-Dawley; Trinitrobenzenesulfonic Acid | 2014 |
ClC-3 chloride channel/antiporter defect contributes to inflammatory bowel disease in humans and mice.
Topics: Animals; Antiporters; Apoptosis; Blotting, Western; Chloride Channels; Colitis, Ulcerative; Crohn Disease; Dextran Sulfate; Disease Models, Animal; Electrophoresis, Polyacrylamide Gel; Gastrointestinal Tract; Humans; In Situ Nick-End Labeling; Mice; Mice, Inbred C57BL; Mice, Knockout; Paneth Cells; Trinitrobenzenesulfonic Acid | 2014 |
Colonic expression of the peptide transporter PEPT1 is downregulated during intestinal inflammation and is not required for NOD2-dependent immune activation.
Topics: Acetylmuramyl-Alanyl-Isoglutamine; Adolescent; Adult; Aged; Animals; Colitis; Colitis, Ulcerative; Crohn Disease; Cytokines; Dextran Sulfate; Disease Models, Animal; Down-Regulation; Female; Gene Knockdown Techniques; Genotype; Humans; Ileitis; Immunity, Mucosal; Male; Mice; Mice, Inbred C57BL; Middle Aged; Nod2 Signaling Adaptor Protein; Peptide Transporter 1; Polymorphism, Single Nucleotide; RNA, Messenger; Symporters; Tissue Culture Techniques; Trinitrobenzenesulfonic Acid; Young Adult | 2014 |
Pyruvate kinase M2 regulates apoptosis of intestinal epithelial cells in Crohn's disease.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Carrier Proteins; Case-Control Studies; Colon; Crohn Disease; Disease Models, Animal; Epithelial Cells; Female; HT29 Cells; Humans; Inflammation Mediators; Intestinal Mucosa; Membrane Proteins; Mice; Mice, Inbred BALB C; Prospective Studies; Pyruvate Kinase; RNA Interference; Signal Transduction; Thyroid Hormone-Binding Proteins; Thyroid Hormones; Time Factors; Transfection; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha | 2015 |
Inhibition of the interleukin-23/interleukin-17 pathway by anti-interleukin-23p19 monoclonal antibody attenuates 2,4,6-trinitrobenzene sulfonic acid-induced Crohn's disease in rats.
Topics: Animals; Antibodies, Monoclonal; Crohn Disease; Disease Models, Animal; Interleukin-17; Interleukin-23; Male; Nuclear Receptor Subfamily 1, Group F, Member 3; Rats; Rats, Sprague-Dawley; RNA, Messenger; Severity of Illness Index; Trinitrobenzenesulfonic Acid | 2014 |
Anti-inflammatory action of a novel orally available peptide 317 in mouse models of inflammatory bowel diseases.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Animals; Anti-Inflammatory Agents; Biological Availability; Case-Control Studies; Colitis, Ulcerative; Crohn Disease; Cytokines; Dextran Sulfate; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Male; Mice; Mice, Inbred BALB C; Middle Aged; Peptides, Cyclic; Real-Time Polymerase Chain Reaction; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha; Young Adult | 2014 |
Oridonin's therapeutic effect: suppressing Th1/Th17 simultaneously in a mouse model of Crohn's disease.
Topics: Animals; Apoptosis; Cells, Cultured; Crohn Disease; Disease Models, Animal; Diterpenes, Kaurane; Interferon-gamma; Interleukin-17; Male; Mice, Inbred BALB C; NF-kappa B; Phytotherapy; Spleen; Th1 Cells; Th17 Cells; Trinitrobenzenesulfonic Acid; Up-Regulation | 2015 |
Alleviated mucosal and neuronal damage in a rat model of Crohn's disease.
Topics: Animals; Colitis; Colon; Crohn Disease; Disease Models, Animal; Heme Oxygenase (Decyclizing); Intestinal Mucosa; Male; Myenteric Plexus; Rats, Sprague-Dawley; Recurrence; Remission Induction; RNA, Messenger; Time Factors; Trinitrobenzenesulfonic Acid; Up-Regulation | 2014 |
Comparison of noncontrast MRI magnetization transfer and T2 -Weighted signal intensity ratios for detection of bowel wall fibrosis in a Crohn's disease animal model.
Topics: Animals; Collagen; Colon; Crohn Disease; Disease Models, Animal; Fibrosis; Inflammation; Intestinal Mucosa; Intestines; Magnetic Resonance Imaging; Rats; Rats, Inbred Lew; ROC Curve; Sensitivity and Specificity; Signal Processing, Computer-Assisted; Trinitrobenzenesulfonic Acid | 2015 |
Vacuolar protein sorting 4B regulates apoptosis of intestinal epithelial cells via p38 MAPK in Crohn's disease.
Topics: Adenosine Triphosphatases; Animals; Apoptosis; ATPases Associated with Diverse Cellular Activities; Blotting, Western; Caspase 3; Cell Proliferation; Colitis; Crohn Disease; Endosomal Sorting Complexes Required for Transport; Epithelial Cells; Female; HT29 Cells; Humans; Immunoenzyme Techniques; Intestinal Mucosa; Mice; Mice, Inbred BALB C; Mice, Nude; p38 Mitogen-Activated Protein Kinases; RNA, Small Interfering; Signal Transduction; Trinitrobenzenesulfonic Acid; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2015 |
[Experimental study of adipose-derived mesenchymal stem cells in the treatment of Crohn's disease].
Topics: Adipocytes; Animals; Colitis; Crohn Disease; Cytokines; Disease Models, Animal; Down-Regulation; Female; Inflammatory Bowel Diseases; Mesenchymal Stem Cells; Mice; Mice, Inbred BALB C; Trinitrobenzenesulfonic Acid; Up-Regulation | 2015 |
miR-19b downregulates intestinal SOCS3 to reduce intestinal inflammation in Crohn's disease.
Topics: 3' Untranslated Regions; Adult; Animals; Base Sequence; Caco-2 Cells; Chemokine CCL20; Chemokines; Colitis; Crohn Disease; Down-Regulation; Female; HT29 Cells; Humans; Immunohistochemistry; In Situ Hybridization, Fluorescence; Intestinal Mucosa; Male; Mice; MicroRNAs; Middle Aged; Rats; Real-Time Polymerase Chain Reaction; RNA Interference; RNA, Messenger; RNA, Small Interfering; RNA, Untranslated; Sequence Alignment; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; Trinitrobenzenesulfonic Acid | 2015 |
SGK1 inhibits cellular apoptosis and promotes proliferation via the MEK/ERK/p53 pathway in colitis.
Topics: Animals; Apoptosis; Cell Proliferation; Colitis; Colon; Crohn Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Female; HCT116 Cells; Humans; Immediate-Early Proteins; Intestinal Mucosa; MAP Kinase Kinase 1; Mice, Inbred BALB C; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Rabbits; RNA Interference; Signal Transduction; Time Factors; Transfection; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53 | 2015 |
Deficiency of Nuclear Receptor Nur77 Aggravates Mouse Experimental Colitis by Increased NFκB Activity in Macrophages.
Topics: Animals; Cell Line; Colitis; Colitis, Ulcerative; Colon; Crohn Disease; Cytokines; Dextran Sulfate; Disease Models, Animal; Epithelial Cells; Female; Forkhead Transcription Factors; Gene Expression Regulation; Humans; Intestinal Mucosa; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; Nuclear Receptor Subfamily 4, Group A, Member 1; RAW 264.7 Cells; Trinitrobenzenesulfonic Acid | 2015 |
Behavioral despair associated with a mouse model of Crohn's disease: Role of nitric oxide pathway.
Topics: Animals; Antidepressive Agents; Colitis; Colon; Crohn Disease; Depression; Disease Models, Animal; Enzyme Inhibitors; Guanidines; Hippocampus; Male; Mice; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Signal Transduction; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha | 2016 |
Catechin-7-O-β-D-glucopyranoside isolated from the seed of Phaseolus calcaratus Roxburgh ameliorates experimental colitis in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Catechin; Crohn Disease; Gene Expression Regulation; Glucosides; Glutathione; Male; Malondialdehyde; Mucins; Peroxidase; Phaseolus; Phosphorylation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Seeds; Trinitrobenzenesulfonic Acid | 2015 |
Interleukin 19 reduces inflammation in chemically induced experimental colitis.
Topics: Animals; Colitis; Crohn Disease; Cytokines; Inflammation; Interleukin-10; Interleukins; Mice; Mice, Inbred C57BL; Mice, Knockout; Recovery of Function; T-Lymphocytes; Trinitrobenzenesulfonic Acid | 2015 |
Mycophenolate Mofetil Modulates Differentiation of Th1/Th2 and the Secretion of Cytokines in an Active Crohn's Disease Mouse Model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Differentiation; Colitis; Crohn Disease; Disease Models, Animal; Female; Gene Expression; Immunosuppressive Agents; Interferon-gamma; Interleukin-12; Interleukin-1beta; Interleukin-6; Mice; Mice, Inbred BALB C; Mycophenolic Acid; Spleen; Th1 Cells; Th1-Th2 Balance; Th2 Cells; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha | 2015 |
AT1R blocker losartan attenuates intestinal epithelial cell apoptosis in a mouse model of Crohn's disease.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Crohn Disease; Cytokines; Disease Models, Animal; Epithelial Cells; Inflammation Mediators; Intestinal Mucosa; Intestines; Losartan; Male; Mice, Inbred C57BL; Permeability; Trinitrobenzenesulfonic Acid; Up-Regulation | 2016 |
Aryl hydrocarbon receptor-driven signals inhibit collagen synthesis in the gut.
Topics: Actins; Adult; Aged; Animals; Azo Compounds; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type III; Constriction, Pathologic; Crohn Disease; Extracellular Signal-Regulated MAP Kinases; Female; Fibroblasts; Fibrosis; Gastrointestinal Tract; Humans; Mice; Mice, Inbred BALB C; Middle Aged; p38 Mitogen-Activated Protein Kinases; Pyrazoles; Receptors, Aryl Hydrocarbon; Transforming Growth Factor beta1; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha | 2016 |
Dysbiosis of the fecal microbiota in the TNBS-induced Crohn's disease mouse model.
Topics: Animals; Crohn Disease; Disease Models, Animal; DNA, Bacterial; Dysbiosis; Feces; Gastrointestinal Microbiome; Intestines; Male; Mice; Mice, Inbred BALB C; RNA, Ribosomal, 16S; Sequence Analysis, DNA; Trinitrobenzenesulfonic Acid | 2016 |
Raf kinase inhibitor protein mediates intestinal epithelial cell apoptosis and promotes IBDs in humans and mice.
Topics: Animals; Apoptosis; Colitis; Colitis, Ulcerative; Crohn Disease; Dextran Sulfate; Epithelial Cells; HCT116 Cells; Homeostasis; Humans; Intestinal Mucosa; MAP Kinase Kinase Kinases; Mice; Mice, Knockout; Phosphatidylethanolamine Binding Protein; Phosphorylation; Severity of Illness Index; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha | 2017 |
MicroRNA-124 Promotes Intestinal Inflammation by Targeting Aryl Hydrocarbon Receptor in Crohn's Disease.
Topics: Adolescent; Adult; Aged; Animals; Basic Helix-Loop-Helix Transcription Factors; Biomarkers; Caco-2 Cells; Colitis; Colon; Crohn Disease; Cytokines; Down-Regulation; Female; HT29 Cells; Humans; Intestinal Mucosa; Male; Mice; Mice, Inbred BALB C; MicroRNAs; Middle Aged; Real-Time Polymerase Chain Reaction; Receptors, Aryl Hydrocarbon; Trinitrobenzenesulfonic Acid; Up-Regulation; Young Adult | 2016 |
E3 Ubiquitin ligase RNF183 Is a Novel Regulator in Inflammatory Bowel Disease.
Topics: Adolescent; Adult; Aged; Animals; Biomarkers; Blotting, Western; Case-Control Studies; Colitis; Colon; Crohn Disease; Female; Humans; Immunohistochemistry; Male; Mice; Mice, Inbred BALB C; MicroRNAs; Middle Aged; NF-kappa B; NF-KappaB Inhibitor alpha; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; Trinitrobenzenesulfonic Acid; Ubiquitin-Protein Ligases; Up-Regulation; Young Adult | 2016 |
Eosinophils Contribute to Intestinal Inflammation via Chemoattractant Receptor-homologous Molecule Expressed on Th2 Cells, CRTH2, in Experimental Crohn's Disease.
Topics: Adult; Aged; Animals; Biomarkers; Blotting, Western; Case-Control Studies; Colitis; Colon; Crohn Disease; Cytokines; Eosinophils; Female; Flow Cytometry; Humans; Immunoassay; Immunohistochemistry; Intestinal Mucosa; Male; Mice; Mice, Knockout; Middle Aged; Receptors, Immunologic; Receptors, Prostaglandin; Th2 Cells; Trinitrobenzenesulfonic Acid | 2016 |
Insight into the pharmacokinetic behavior of tanshinone IIA in the treatment of Crohn's disease: comparative data for tanshinone IIA and its two glucuronidated metabolites in normal and recurrent colitis models after oral administration.
Topics: Abietanes; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Crohn Disease; Disease Models, Animal; Glucuronosyltransferase; Mice; Trinitrobenzenesulfonic Acid; UDP-Glucuronosyltransferase 1A9 | 2017 |
Comparison of Adipose-Derived and Bone Marrow Mesenchymal Stromal Cells in a Murine Model of Crohn's Disease.
Topics: Adipose Tissue; Animals; Bone Marrow Cells; Colitis; Colon; Crohn Disease; Cytokines; Disease Models, Animal; Flow Cytometry; Immunohistochemistry; Injections, Intraperitoneal; Interleukin-10; Interleukin-12; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Mice, Inbred BALB C; Real-Time Polymerase Chain Reaction; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2017 |
The suppressor of cytokine signaling SOCS1 promotes apoptosis of intestinal epithelial cells via p53 signaling in Crohn's disease.
Topics: Animals; Apoptosis; Colitis; Crohn Disease; Epithelial Cells; Female; Gene Knockdown Techniques; HT29 Cells; Humans; Interferon-gamma; Intestines; Mice, Inbred BALB C; Signal Transduction; Suppressor of Cytokine Signaling 1 Protein; Trinitrobenzenesulfonic Acid; Tumor Suppressor Protein p53 | 2016 |
Murine Trinitrobenzoic Acid-Induced Colitis as a Model of Crohn's Disease.
Topics: Adaptive Immunity; Animals; Colitis; Crohn Disease; Disease Models, Animal; Gastrointestinal Microbiome; Humans; Immunity, Innate; Mice; Mice, Knockout; Trinitrobenzenesulfonic Acid | 2016 |
Structural and molecular features of intestinal strictures in rats with Crohn's-like disease.
Topics: Animals; Apoptosis; Blotting, Western; Colitis; Colon; Constriction, Pathologic; Crohn Disease; Disease Models, Animal; Gene Expression Regulation; Immunohistochemistry; Intestinal Obstruction; Male; Matrix Metalloproteinase 9; Microscopy, Electron, Transmission; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; RNA, Messenger; Time Factors; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta2; Transforming Growth Factor beta3; Trinitrobenzenesulfonic Acid | 2016 |
Enhanced effect of κ-carrageenan on TNBS-induced inflammation in mice.
Topics: Animals; Carrageenan; CD4-Positive T-Lymphocytes; Colitis; Colon; Crohn Disease; Cytokines; Disease Models, Animal; Female; Humans; Male; Mice; NF-kappa B; Toll-Like Receptor 4; Trinitrobenzenesulfonic Acid | 2016 |
Fecal Lipocalin-2 as a Sensitive and Noninvasive Biomarker in the TNBS Crohn's Inflammatory Bowel Disease Model.
Topics: Animals; Biomarkers; Colon; Crohn Disease; Disease Models, Animal; Feces; Female; Lipocalin-2; Mice, Inbred BALB C; Research Design; Sensitivity and Specificity; Trinitrobenzenesulfonic Acid | 2016 |
Vitamin D treatment attenuates 2,4,6-trinitrobenzene sulphonic acid (TNBS)-induced colitis but not oxazolone-induced colitis.
Topics: Animals; Apoptosis; Colitis, Ulcerative; Crohn Disease; Cytokines; Disease Models, Animal; Female; Inflammation; Intestinal Mucosa; Male; Mice; Mice, Inbred C57BL; Oxazolone; T-Lymphocytes, Regulatory; Th1 Cells; Th17 Cells; Th2 Cells; Trinitrobenzenesulfonic Acid; Vitamin D | 2016 |
Rectal Delivery of a DNAzyme That Specifically Blocks the Transcription Factor GATA3 and Reduces Colitis in Mice.
Topics: Administration, Rectal; Adolescent; Adult; Aged; Animals; Case-Control Studies; Child; Colitis; Colitis, Ulcerative; Colon; Crohn Disease; Cytokines; Disease Models, Animal; DNA, Catalytic; Female; GATA3 Transcription Factor; Humans; Intestinal Mucosa; Male; Mice; Mice, Knockout; Middle Aged; Oxazolone; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; RNA, Messenger; T-Lymphocytes; Trinitrobenzenesulfonic Acid; Young Adult | 2017 |
A whole animal chemical screen approach to identify modifiers of intestinal neutrophilic inflammation.
Topics: Animals; Animals, Genetically Modified; Anti-Inflammatory Agents; Colitis, Ulcerative; Crohn Disease; Dextran Sulfate; Disease Models, Animal; Dopamine Agonists; Dysbiosis; Embryo, Nonmammalian; Gene Expression; High-Throughput Screening Assays; Humans; Immunologic Factors; Intestines; Neutrophils; Receptors, Cholecystokinin; Receptors, Dopamine; Small Molecule Libraries; Trinitrobenzenesulfonic Acid; Zebrafish | 2017 |
The signaling axis of microRNA-31/interleukin-25 regulates Th1/Th17-mediated inflammation response in colitis.
Topics: 3' Untranslated Regions; Adolescent; Adult; Animals; Antibodies, Blocking; Colitis; Crohn Disease; Disease Models, Animal; Female; Humans; Inflammation; Interleukin-10; Interleukin-17; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Knockout; MicroRNAs; Middle Aged; Signal Transduction; Th1 Cells; Th17 Cells; Trinitrobenzenesulfonic Acid; Young Adult | 2017 |
SPECT-computed tomography in rats with TNBS-induced colitis: A first step toward functional imaging.
Topics: Animals; Blotting, Western; Citrates; Colitis; Colon; Crohn Disease; Cyclooxygenase 2; Disease Models, Animal; Feasibility Studies; Gallium; Male; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Tomography, Emission-Computed, Single-Photon; Trinitrobenzenesulfonic Acid | 2017 |
Recombinant adeno-associated virus carrying thymosin β
Topics: Animals; Cell Proliferation; Colitis, Ulcerative; Colon; Crohn Disease; Dependovirus; Dextran Sulfate; Disease Models, Animal; DNA, Recombinant; Enterocytes; Enzyme-Linked Immunosorbent Assay; Genetic Vectors; Immunochemistry; Interleukin-10; Interleukin-1beta; Intestinal Mucosa; Male; Malondialdehyde; Mice; Mice, Inbred BALB C; Peroxidase; Superoxide Dismutase; Thymosin; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha | 2017 |
Zebrafish screens for new colitis treatments - a bottom-up approach.
Topics: Animals; Animals, Genetically Modified; Anti-Inflammatory Agents; Colitis, Ulcerative; Crohn Disease; Dextran Sulfate; Disease Models, Animal; Dysbiosis; High-Throughput Screening Assays; Humans; Immunologic Factors; Intestines; Neutrophils; Trinitrobenzenesulfonic Acid; Zebrafish | 2017 |
Microtubule-associated protein 1S-related autophagy inhibits apoptosis of intestinal epithelial cells via Wnt/β-catenin signaling in Crohn's disease.
Topics: Animals; Apoptosis; Autophagy; Benzothiazoles; Blotting, Western; Caspase 3; Cells, Cultured; Colitis; Crohn Disease; Epithelial Cells; HCT116 Cells; Humans; Immunohistochemistry; Intestinal Mucosa; Mice; Microscopy, Confocal; Microtubule-Associated Proteins; RNA Interference; Trinitrobenzenesulfonic Acid; Wnt Signaling Pathway | 2017 |
Evaluation of anti-inflammatory effect of silver-coated glass beads in mice with experimentally induced colitis as a new type of treatment in inflammatory bowel disease.
Topics: Animals; Anti-Inflammatory Agents; Chemistry, Pharmaceutical; Colitis; Colitis, Ulcerative; Crohn Disease; Dextran Sulfate; Disease Models, Animal; Inflammation; Male; Mice; Mice, Inbred BALB C; Silver; Trinitrobenzenesulfonic Acid | 2017 |
Si-Ni-San, a traditional Chinese prescription, and its active ingredient glycyrrhizin ameliorate experimental colitis through regulating cytokine balance.
Topics: Animals; Body Weight; Colitis; Colon; Crohn Disease; Cytokines; Diarrhea; Disease Models, Animal; Drugs, Chinese Herbal; Female; Glycyrrhizic Acid; Humans; Medicine, Chinese Traditional; Mice; Mice, Inbred C57BL; Peroxidase; Trinitrobenzenesulfonic Acid | 2009 |
Development of recombinant vaccines against IL-12/IL-23 p40 and in vivo evaluation of their effects in the downregulation of intestinal inflammation in murine colitis.
Topics: Animals; Antibody Affinity; Colitis; Collagen; Colon; Crohn Disease; Immunoglobulin G; Inflammation; Interleukin-12 Subunit p40; Interleukin-23; Male; Mice; Mice, Inbred BALB C; Models, Animal; Trinitrobenzenesulfonic Acid; Vaccines, Synthetic | 2009 |
The bile acid receptor FXR is a modulator of intestinal innate immunity.
Topics: Acute Disease; Adult; Animals; Chronic Disease; Colitis; Crohn Disease; Female; Humans; Immunity, Innate; Interleukin-1beta; Intestinal Mucosa; Intestines; Lipopolysaccharides; Macrophages; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mice, SCID; NF-kappa B; Receptors, Cytoplasmic and Nuclear; Trinitrobenzenesulfonic Acid | 2009 |
Lipopolysaccharide exposure is linked to activation of the acute phase response and growth failure in pediatric Crohn's disease and murine colitis.
Topics: Acute-Phase Proteins; Acute-Phase Reaction; Adolescent; Adult; Animals; Biomarkers; Carrier Proteins; Case-Control Studies; Child; Child, Preschool; Colitis, Ulcerative; Colon; Crohn Disease; Cytokines; Enema; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Growth Disorders; Humans; Infant; Lipopolysaccharides; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Toll-Like Receptor 4; Trinitrobenzenesulfonic Acid; Young Adult | 2010 |
Efficacy of a novel sphingosine kinase inhibitor in experimental Crohn's disease.
Topics: Adamantane; Aminosalicylic Acids; Animals; Body Weight; Colon; Crohn Disease; Disease Models, Animal; Drug Therapy, Combination; Enzyme Inhibitors; Epithelial Cells; Female; Gastrointestinal Agents; Humans; Interleukin-1beta; Leukocytes; Male; Mice; Mice, Inbred C57BL; Neutrophils; Peroxidase; Phosphotransferases (Alcohol Group Acceptor); Prednisolone; Pyridines; Rats; Rats, Sprague-Dawley; Treatment Outcome; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha | 2010 |
Arsenic trioxide reduces 2,4,6-trinitrobenzene sulfonic acid-induced murine colitis via nuclear factor-κB down-regulation and caspase-3 activation.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Caspase 3; Colitis; Colon; Crohn Disease; Cytokines; Disease Models, Animal; Humans; Male; Mice; Mice, Inbred BALB C; NF-kappa B; Nitric Oxide Synthase Type II; Oxides; Peroxidase; Trinitrobenzenesulfonic Acid | 2011 |
Differential immune and genetic responses in rat models of Crohn's colitis and ulcerative colitis.
Topics: Animals; Colitis; Colitis, Ulcerative; Crohn Disease; Cytokines; Dextran Sulfate; Disease Models, Animal; Hyperplasia; Hypertrophy; Inflammation; Inflammation Mediators; Muscle, Smooth; Oxidative Stress; Rats; Rats, Sprague-Dawley; Trinitrobenzenesulfonic Acid | 2011 |
Anti-colitis and -adhesion effects of daikenchuto via endogenous adrenomedullin enhancement in Crohn's disease mouse model.
Topics: Adrenomedullin; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Adhesion; Cell Line; Colitis; Colon; Crohn Disease; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Flow Cytometry; Gene Expression; Immunohistochemistry; Interferon-gamma; Intestinal Mucosa; Male; Mice; Mice, Inbred BALB C; Panax; Phytotherapy; Plant Extracts; Rats; Serum Amyloid A Protein; Treatment Outcome; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha; Up-Regulation; Zanthoxylum; Zingiberaceae | 2010 |
Use of superoxide dismutase and catalase producing lactic acid bacteria in TNBS induced Crohn's disease in mice.
Topics: Animals; Body Weight; Catalase; Colon; Crohn Disease; Cytokines; Disease Models, Animal; Female; Genetic Engineering; Histocytochemistry; Inflammation; Intestine, Large; Lacticaseibacillus casei; Liver; Mice; Mice, Inbred BALB C; Probiotics; Superoxide Dismutase; Trinitrobenzenesulfonic Acid | 2011 |
Treatment with Bifidobacterium bifidum 17 partially protects mice from Th1-driven inflammation in a chemically induced model of colitis.
Topics: Animals; Bifidobacterium; Colitis; Crohn Disease; Cytokines; Disease Models, Animal; Inflammation Mediators; Inflammatory Bowel Diseases; Interleukin-1beta; Intestinal Mucosa; Male; Mice; Mice, Inbred C57BL; Probiotics; T-Lymphocytes, Helper-Inducer; Trinitrobenzenesulfonic Acid | 2011 |
Pharmacologic evaluation of sulfasalazine, FTY720, and anti-IL-12/23p40 in a TNBS-induced Crohn's disease model.
Topics: Animals; Antibodies, Monoclonal; Crohn Disease; Diarrhea; Disease Models, Animal; Female; Fingolimod Hydrochloride; Gastrointestinal Agents; Interleukin-12; Interleukin-23; Mice; Mice, Inbred BALB C; Organ Size; Propylene Glycols; Sphingosine; Sulfasalazine; Trinitrobenzenesulfonic Acid; Weight Loss | 2011 |
Protective effect of ellagic acid, a natural polyphenolic compound, in a murine model of Crohn's disease.
Topics: Active Transport, Cell Nucleus; Acute Disease; Animals; Cell Nucleus; Colon; Crohn Disease; Cyclooxygenase 2; Ellagic Acid; Flavonoids; I-kappa B Kinase; Intestinal Mucosa; Leukocytes; Male; Mitogen-Activated Protein Kinases; Nitric Oxide Synthase Type II; Peroxidase; Phenols; Phosphorylation; Polyphenols; Rats; Rats, Wistar; Signal Transduction; Transcription Factor RelA; Transcriptional Activation; Trinitrobenzenesulfonic Acid | 2011 |
Ultrasound elasticity imaging for detecting intestinal fibrosis and inflammation in rats and humans with Crohn's disease.
Topics: Animals; Biomechanical Phenomena; Colitis; Colon; Crohn Disease; Diagnosis, Differential; Diagnostic Imaging; Disease Models, Animal; Disease Progression; Elasticity; Female; Fibrosis; Humans; Inflammation; Inflammatory Bowel Diseases; Intestine, Small; Pilot Projects; Rats; Rats, Inbred Lew; Trinitrobenzenesulfonic Acid; Ultrasonography | 2011 |
Daikenchuto (TU-100) ameliorates colon microvascular dysfunction via endogenous adrenomedullin in Crohn's disease rat model.
Topics: Adrenomedullin; Amides; Animals; Calcitonin Gene-Related Peptide; Cell Line; Colitis; Colon; Crohn Disease; Disease Models, Animal; Intestinal Mucosa; Male; Microvessels; Panax; Plant Extracts; Rats; Rats, Sprague-Dawley; RNA, Messenger; Trinitrobenzenesulfonic Acid; Up-Regulation; Vasodilation; Zanthoxylum; Zingiberaceae | 2011 |
Spironolactone and colitis: increased mortality in rodents and in humans.
Topics: Animals; Clostridioides difficile; Clostridium Infections; Colitis; Crohn Disease; Female; Fibrosis; Hospitalization; Humans; Inflammation; Intestinal Diseases; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Myofibroblasts; Rats; Retrospective Studies; Spironolactone; Survival Rate; Transforming Growth Factor beta; Trinitrobenzenesulfonic Acid | 2012 |
[Crohn disease in rats induced by different concentrations of trinitrobenzenesulfonic acid and ethanol].
Topics: Animals; Crohn Disease; Disease Models, Animal; Ethanol; Rats; Rats, Wistar; Trinitrobenzenesulfonic Acid | 2011 |
Oral treatment with Hev b 13 ameliorates experimental colitis in mice.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigens, Plant; Colitis; Colon; Crohn Disease; Diarrhea; Female; Humans; Interleukin-10; Mice; Mice, Inbred BALB C; Plant Proteins; Rectal Prolapse; Trinitrobenzenesulfonic Acid; Weight Loss | 2012 |
Dietary supplementation of an ellagic acid-enriched pomegranate extract attenuates chronic colonic inflammation in rats.
Topics: Animals; Anti-Inflammatory Agents; Colitis; Colon; Crohn Disease; Cyclooxygenase 2; Dietary Supplements; Disease Models, Animal; Ellagic Acid; I-kappa B Proteins; Interferon-alpha; Intestinal Mucosa; Lythraceae; Male; MAP Kinase Kinase 4; MAP Kinase Signaling System; NF-kappa B; NF-KappaB Inhibitor alpha; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Peroxidase; Phosphorylation; Plant Extracts; Polyphenols; Rats; Rats, Wistar; Signal Transduction; Trinitrobenzenesulfonic Acid | 2012 |
Tissue inhibitor of metalloproteinase-3 regulates inflammation in human and mouse intestine.
Topics: Adult; Aged; Amyloid Precursor Protein Secretases; Animals; Cells, Cultured; Colitis; Colitis, Ulcerative; Crohn Disease; Cytokines; Down-Regulation; Gene Knockdown Techniques; Gene Knockout Techniques; Humans; Intestinal Mucosa; Leukocytes, Mononuclear; Mice; Mice, Knockout; Mice, Transgenic; Middle Aged; Oligonucleotides, Antisense; RNA, Messenger; Smad7 Protein; Tissue Inhibitor of Metalloproteinase-3; Transforming Growth Factor beta; Trinitrobenzenesulfonic Acid | 2012 |
Dose-dependent antiinflammatory effect of ursodeoxycholic acid in experimental colitis.
Topics: Administration, Oral; Alkaline Phosphatase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Crohn Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Humans; Intestinal Mucosa; Rats; Rats, Wistar; Trinitrobenzenesulfonic Acid; Ursodeoxycholic Acid | 2013 |
Therapeutic effects of vasoactive intestinal peptide in the trinitrobenzene sulfonic acid mice model of Crohn's disease.
Topics: Animals; Colitis; Crohn Disease; Cytokines; Disease Models, Animal; Down-Regulation; Gastrointestinal Agents; Male; Mice; Mice, Inbred BALB C; Receptors, Vasoactive Intestinal Peptide; Receptors, Vasoactive Intestinal Polypeptide, Type I; Th1 Cells; Th2 Cells; Trinitrobenzenesulfonic Acid; Vasoactive Intestinal Peptide; Wasting Syndrome | 2003 |
Concurrent infection with Schistosoma mansoni attenuates inflammation induced changes in colonic morphology, cytokine levels, and smooth muscle contractility of trinitrobenzene sulphonic acid induced colitis in rats.
Topics: Animals; Colitis; Colon; Crohn Disease; Cytokines; Disease Models, Animal; Intestinal Mucosa; Male; Muscle Contraction; Muscle, Smooth; Peroxidase; Rats; Rats, Wistar; Schistosomiasis mansoni; Spleen; Th1 Cells; Th2 Cells; Trinitrobenzenesulfonic Acid | 2004 |
An interleukin 12 p40-IgG2b fusion protein abrogates T cell mediated inflammation: anti-inflammatory activity in Crohn's disease and experimental colitis in vivo.
Topics: Adult; Animals; Apoptosis; Cell Division; Cells, Cultured; Colitis; Crohn Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Humans; Immunoglobulin G; Interferon-gamma; Interleukin-12; Interleukin-12 Subunit p40; Leukocytes, Mononuclear; Male; Mice; Mice, Inbred BALB C; Middle Aged; Prospective Studies; Protein Subunits; Receptors, Interleukin; Receptors, Interleukin-12; Recombinant Fusion Proteins; Trinitrobenzenesulfonic Acid | 2004 |
Colitis up-regulates local glucocorticoid activation and down-regulates inactivation in colonic tissue.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 11-beta-Hydroxysteroid Dehydrogenase Type 2; Animals; Colitis, Ulcerative; Corticosterone; Crohn Disease; Dextran Sulfate; Disease Models, Animal; Male; Rats; Rats, Wistar; RNA, Messenger; Trinitrobenzenesulfonic Acid | 2004 |
CD40 antisense oligonucleotide inhibition of trinitrobenzene sulphonic acid induced rat colitis.
Topics: Animals; CD40 Antigens; CD40 Ligand; Cells, Cultured; Colitis; Crohn Disease; Drug Design; Gene Expression Regulation; Immunity, Mucosal; Intestinal Mucosa; Liposomes; Male; Muscle, Smooth, Vascular; Oligonucleotides, Antisense; Rats; Rats, Wistar; Transfection; Trinitrobenzenesulfonic Acid; Vascular Cell Adhesion Molecule-1 | 2005 |
Therapeutic effect of the immunomodulator glatiramer acetate on trinitrobenzene sulfonic acid-induced experimental colitis.
Topics: Animals; Colitis; Crohn Disease; Disease Models, Animal; Female; Glatiramer Acetate; Immunosuppressive Agents; Mice; Mice, Inbred BALB C; Multiple Sclerosis; Peptides; Polymers; Severity of Illness Index; Survival Analysis; Trinitrobenzenesulfonic Acid | 2005 |
Inhibition of RICK/nuclear factor-kappaB and p38 signaling attenuates the inflammatory response in a murine model of Crohn disease.
Topics: Animals; Crohn Disease; Cytokines; Disease Models, Animal; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Inhibitors; Female; Imidazoles; Immunoblotting; Inflammation; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence; Models, Biological; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Protein Kinases; Pyridines; Receptor-Interacting Protein Serine-Threonine Kinase 2; Receptor-Interacting Protein Serine-Threonine Kinases; Subcellular Fractions; Trinitrobenzenesulfonic Acid; Up-Regulation | 2005 |
cDNA array analysis of cytokines, chemokines, and receptors involved in the development of TNBS-induced colitis: homeostatic role of VIP.
Topics: Analysis of Variance; Animals; Chemokines; Crohn Disease; Cytokines; Gastrointestinal Agents; Humans; Inflammation; Inflammation Mediators; Male; Mice; Mice, Inbred BALB C; Oligonucleotide Array Sequence Analysis; Receptors, Immunologic; Trinitrobenzenesulfonic Acid; Vasoactive Intestinal Peptide | 2005 |
[Study the effect and mechanism of thalidomide in model of inflammatory bowed disease].
Topics: Animals; Colitis, Ulcerative; Crohn Disease; Female; Inflammatory Bowel Diseases; NF-kappa B; Oxazolone; Rats; Rats, Sprague-Dawley; Thalidomide; Trinitrobenzenesulfonic Acid | 2005 |
Intestinal inflammation-induced growth retardation acts through IL-6 in rats and depends on the -174 IL-6 G/C polymorphism in children.
Topics: Animals; Antibodies; Case-Control Studies; Child; Colitis; Crohn Disease; Disease Models, Animal; Genotype; Growth Disorders; Humans; Inflammation; Insulin-Like Growth Factor I; Interleukin-6; Intestinal Diseases; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Rats; Rats, Wistar; Trinitrobenzenesulfonic Acid | 2005 |
Intestinal gene expression in TNBS treated mice using genechip and subtractive cDNA analysis: implications for Crohn's disease.
Topics: Animals; Crohn Disease; DNA, Complementary; Gene Expression; Humans; Intestinal Mucosa; Male; Mice; Mice, Inbred C57BL; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; RNA; Trinitrobenzenesulfonic Acid | 2005 |
Therapeutic effect of urocortin and adrenomedullin in a murine model of Crohn's disease.
Topics: Adrenomedullin; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Chemokines; Corticotropin-Releasing Hormone; Crohn Disease; Cytokines; Disease Models, Animal; Interleukin-10; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Peptides; Proteins; Th1 Cells; Trinitrobenzenesulfonic Acid; Urocortins | 2006 |
Signal transducer and activator of transcription 5b promotes mucosal tolerance in pediatric Crohn's disease and murine colitis.
Topics: Animals; Carrier Proteins; Child; Colitis; Colon; Crohn Disease; Epithelial Cells; Female; Genetic Predisposition to Disease; Humans; Hypoglycemic Agents; Intestinal Mucosa; Male; Mice; Mice, Inbred C57BL; Mucous Membrane; NF-kappa B; PPAR gamma; Rosiglitazone; Signal Transduction; STAT5 Transcription Factor; Thiazolidinediones; Trinitrobenzenesulfonic Acid | 2006 |
The intestinal anti-inflammatory effects of the novel agent UR-1505 in the TNBS model of rat colitis are mediated by T-lymphocyte inhibition.
Topics: Animals; Anti-Inflammatory Agents; Cells, Cultured; Colitis; Colon; Crohn Disease; Disease Models, Animal; Female; Glutathione; Interferon-gamma; Leukotriene B4; Macrophages; Mice; Mice, Inbred BALB C; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Salicylates; Spleen; T-Lymphocytes; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha | 2007 |
Indomethacin and retinoic acid modify mouse intestinal inflammation and fibrosis: a role for SPARC.
Topics: Animals; Crohn Disease; Disease Models, Animal; Female; Fibrosis; Immunoenzyme Techniques; Indomethacin; Mice; Osteonectin; Random Allocation; Reverse Transcriptase Polymerase Chain Reaction; RNA; Statistics, Nonparametric; Tretinoin; Trinitrobenzenesulfonic Acid | 2008 |
Muramyl dipeptide activation of nucleotide-binding oligomerization domain 2 protects mice from experimental colitis.
Topics: Acetylmuramyl-Alanyl-Isoglutamine; Adjuvants, Immunologic; Animals; Colitis; Crohn Disease; Cytokines; Dendritic Cells; Disease Models, Animal; Disease Susceptibility; Down-Regulation; Immunity, Innate; Interferon Regulatory Factors; Ligands; Mice; Mice, Mutant Strains; Nod2 Signaling Adaptor Protein; RNA, Small Interfering; Toll-Like Receptors; Trinitrobenzenesulfonic Acid | 2008 |
Subcutaneous adipose tissue-derived stem cells facilitate colonic mucosal recovery from 2,4,6-trinitrobenzene sulfonic acid (TNBS)-induced colitis in rats.
Topics: Adiponectin; Adipose Tissue; Animals; Cell Differentiation; Colon; Crohn Disease; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Hepatocyte Growth Factor; Intestinal Mucosa; Rats; Rats, Inbred F344; Stem Cells; Transforming Growth Factor beta; Trinitrobenzenesulfonic Acid; Vascular Endothelial Growth Factor A | 2008 |
Noninvasive ultrasound elasticity imaging (UEI) of Crohn's disease: animal model.
Topics: Animals; Colon; Crohn Disease; Disease Models, Animal; Elasticity; Elasticity Imaging Techniques; Female; Fibrosis; Image Interpretation, Computer-Assisted; In Vitro Techniques; Rats; Rats, Inbred Lew; Sensitivity and Specificity; Stress, Mechanical; Trinitrobenzenesulfonic Acid | 2008 |
Prevention of colonic fibrosis by Boswellia and Scutellaria extracts in rats with colitis induced by 2,4,5-trinitrobenzene sulphonic acid.
Topics: Actins; Animals; Boswellia; CD3 Complex; Colitis; Collagen Type I; Collagen Type II; Collagen Type III; Colon; Connective Tissue Growth Factor; Crohn Disease; Fibrosis; Immediate-Early Proteins; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Male; Models, Animal; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Scutellaria; Smad3 Protein; Smad7 Protein; Transforming Growth Factor beta1; Trinitrobenzenesulfonic Acid | 2008 |
Targeting endocannabinoid degradation protects against experimental colitis in mice: involvement of CB1 and CB2 receptors.
Topics: Amidohydrolases; Animals; Arachidonic Acids; Benzamides; Cannabinoid Receptor Modulators; Carbamates; Colitis; Crohn Disease; Disease Models, Animal; Endocannabinoids; Humans; Mice; Mice, Inbred C57BL; Polymorphism, Genetic; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; RNA, Messenger; Trinitrobenzenesulfonic Acid | 2008 |
The characterization of a rabbit model of inflammatory bowel disease.
Topics: Animals; Colitis, Ulcerative; Crohn Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Female; Inflammatory Bowel Diseases; Rabbits; Sodium Chloride; Time Factors; Trinitrobenzenesulfonic Acid | 1995 |
Antibodies to interleukin 12 abrogate established experimental colitis in mice.
Topics: Animals; Antibodies, Monoclonal; Base Sequence; CD4 Lymphocyte Count; Colitis; Colon; Crohn Disease; Disease Models, Animal; Interferon-gamma; Interleukin-12; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Molecular Sequence Data; Spleen; Trinitrobenzenesulfonic Acid | 1995 |
Immunosuppressive agents in the treatment of Crohn's disease and ulcerative colitis.
Topics: Animals; Antibodies, Monoclonal; CD4 Antigens; Colitis; Colitis, Ulcerative; Crohn Disease; Humans; Immunosuppressive Agents; Mercaptopurine; Rats; Remission Induction; Trinitrobenzenesulfonic Acid | 1995 |
Therapeutic efficacy of N-3 polyunsaturated fatty acid in experimental Crohn's disease.
Topics: alpha-Linolenic Acid; Animals; Colitis; Colon; Crohn Disease; Fatty Acids, Omega-3; Fish Oils; Food, Formulated; Leukotriene B4; Male; Organ Size; Rats; Rats, Sprague-Dawley; Safflower Oil; Trinitrobenzenesulfonic Acid | 1995 |
Tolerance towards resident intestinal flora in mice is abrogated in experimental colitis and restored by treatment with interleukin-10 or antibodies to interleukin-12.
Topics: Animals; Antibodies, Monoclonal; Bacteria; Colitis; Colon; Crohn Disease; Disease Models, Animal; Humans; Immune Tolerance; Immunologic Factors; Interleukin-10; Interleukin-12; Intestine, Small; Intestines; Leukocytes, Mononuclear; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Peyer's Patches; Rats; Recombinant Proteins; Species Specificity; Specific Pathogen-Free Organisms; Spleen; Trinitrobenzenesulfonic Acid | 1996 |
Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-kappa B abrogates established experimental colitis in mice.
Topics: Adrenal Cortex Hormones; Adult; Aged; Animals; Base Sequence; Cells, Cultured; Crohn Disease; Cytokines; Disease Models, Animal; DNA; Enterocolitis; Female; Humans; Interleukin-10; Male; Mice; Middle Aged; Molecular Sequence Data; NF-kappa B; Oligonucleotides, Antisense; Transcription Factor RelA; Trinitrobenzenesulfonic Acid | 1996 |
Excess glutamine exacerbates trinitrobenzenesulfonic acid-induced colitis in rats.
Topics: Animals; Colitis; Colon; Crohn Disease; Female; Food, Formulated; Glutamine; Rats; Rats, Sprague-Dawley; Time Factors; Trinitrobenzenesulfonic Acid | 1997 |
Viral vectors expressing immunoregulatory cytokines to treat inflammatory bowel disease.
Topics: Adenoviridae; Animals; Combined Modality Therapy; Crohn Disease; Disease Models, Animal; Genetic Therapy; Genetic Vectors; Humans; Interleukin-4; Rats; Trinitrobenzenesulfonic Acid | 1998 |
CD45RChighCD4+ intestinal mucosal lymphocytes infiltrating in the inflamed colonic mucosa of a novel rat colitis model induced by TNB immunization.
Topics: Animals; Antibodies, Monoclonal; Base Sequence; CD4 Antigens; CD4-Positive T-Lymphocytes; Colitis; Colon; Crohn Disease; Cytokines; Disease Models, Animal; DNA Primers; Female; Gene Expression; Humans; Immunization; Intestinal Mucosa; Leukocyte Common Antigens; Polymerase Chain Reaction; Rats; Rats, Wistar; RNA, Messenger; Trinitrobenzenesulfonic Acid | 1998 |
Antitumor necrosis factor therapy in rat chronic granulomatous colitis: critical dose-timing effects on outcome.
Topics: Animals; Antibodies, Monoclonal; Colon; Colony Count, Microbial; Crohn Disease; Dose-Response Relationship, Drug; Male; Neutralization Tests; Rats; Rats, Sprague-Dawley; Time Factors; Treatment Outcome; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha | 1998 |
Anti-IL12 imposes the death sentence on Th1 cells in TNBS colitis--is there a light at the end of the tunnel for Crohn's disease?
Topics: Animals; Antibodies; Apoptosis; Crohn Disease; Disease Models, Animal; Humans; Inflammation; Interleukin-12; Mice; T-Lymphocytes, Helper-Inducer; Trinitrobenzenesulfonic Acid | 2000 |
Interleukin 16 is up-regulated in Crohn's disease and participates in TNBS colitis in mice.
Topics: Animals; Antibodies, Monoclonal; Colitis; Colon; Crohn Disease; Disease Models, Animal; Gene Expression Regulation; Humans; Interleukin-16; Intestinal Mucosa; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription, Genetic; Trinitrobenzenesulfonic Acid | 2000 |
Macrophage-derived IL-18-mediated intestinal inflammation in the murine model of Crohn's disease.
Topics: Animals; Antibodies; Colitis; Crohn Disease; Disease Models, Animal; Humans; Inflammation; Interleukin-18; Intestinal Mucosa; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Trinitrobenzenesulfonic Acid | 2001 |
Contrasting roles of IL-12p40 and IL-12p35 in the development of hapten-induced colitis.
Topics: Animals; Basement Membrane; CD8-Positive T-Lymphocytes; Cells, Cultured; Colon; Crohn Disease; Disease Models, Animal; Female; Haptens; Interferon-gamma; Interleukin-12; Interleukin-18; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Receptors, Interleukin; Receptors, Interleukin-12; T-Lymphocytes; Trinitrobenzenesulfonic Acid | 2002 |
The role of mast cells in the development of 2, 4, 6-trinitrobenzene sulfonic acid-induced colitis in rats.
Topics: Animals; Chymases; Colitis; Colon; Crohn Disease; Male; Mast Cells; Models, Animal; Rats; Serine Endopeptidases; Trinitrobenzenesulfonic Acid | 2002 |
Amelioration of dextran sulfate sodium-induced colitis by anti-macrophage migration inhibitory factor antibody in mice.
Topics: Animals; Antibodies; Cecum; Colitis; Colitis, Ulcerative; Colon; Crohn Disease; Dextran Sulfate; Humans; Immunohistochemistry; Interferon-gamma; Interleukin-4; Macrophage Migration-Inhibitory Factors; Male; Matrix Metalloproteinase 13; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; RNA, Messenger; Time Factors; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha | 2002 |
Dietary fish oil reduces progression of chronic inflammatory lesions in a rat model of granulomatous colitis.
Topics: Animals; Body Weight; Cod Liver Oil; Crohn Disease; Dietary Fats; Dinoprostone; Fatty Acids; Fatty Acids, Omega-3; Fish Oils; Helianthus; Leukotriene B4; Male; Plant Oils; Rats; Rats, Inbred Strains; Thromboxane B2; Trinitrobenzenesulfonic Acid | 1990 |