trinitrobenzenesulfonic acid and Cirrhosis

trinitrobenzenesulfonic acid has been researched along with Cirrhosis in 65 studies

Research

Studies (65)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	3 (4.62)	18.2507
2000's	12 (18.46)	29.6817
2010's	43 (66.15)	24.3611
2020's	7 (10.77)	2.80

Authors

Authors	Studies
Boirivant, M; Butera, A; Campanile, D; Crippa, L; Di Carlo, N; Labbaye, C; Quaranta, MT; Saulle, E; Spinello, I	1
Bunnett, NW; Chupina Estrada, A; Fontenot, L; Ho, W; Jensen, DD; Koon, HW; Mattai, SA; Nelson, B; Rieder, F; Shih, DQ; Wang, J; Xie, Y	1
Chen, M; Li, J; Liu, L; Zhao, Q	1
Cui, J; Gao, J; Guo, W; Jiang, C; Jiao, C; Li, Y; Liu, W; Xu, Q; Zhong, H	1
Appendino, G; Calzado, MA; Collado, JA; García-Martín, A; Minassi, A; Muñoz, E; Palomares, B; Prados, ME; Unciti-Broceta, JD	1
da Cunha, VP; Machado, DCC; Miyoshi, A; Pereira, VB; Preisser, TM; Santana, MP	1
Amamou, A; Aziz, M; Goichon, A; Guérin, C; Marion-Letellier, R; Rouland, M; Savoye, G; Yaker, L	1
Guan, Y; Liu, W; Pan, D; Sun, Y; Tan, Y; Wang, D; Yang, J; Zheng, C	1
Alós, R; Barrachina, MD; Bernardo, D; Calatayud, S; Esplugues, JV; Gisbert-Ferrándiz, L; Hernández, C; Macías-Ceja, DC; Navarro-Vicente, F; Ortiz-Masiá, D; Salvador, P	1
Li, Q; Liu, L; Noë, M; Pasricha, PJ; Zhu, Y	1
Bevivino, G; Colantoni, A; De Simone, V; Di Giovangiulio, M; Franzè, E; Izzo, R; Marafini, I; Monteleone, G; Monteleone, I; Ortenzi, A; Rizzo, A; Sedda, S	1
He, X; Huang, Q; Ke, J; Lan, P; Lian, L; Qin, H; Xie, M; Zhang, L	1
Bernstein, CN; Guan, Q; Peng, Z; Qing, G; Wang, S; Warrington, RJ; Weiss, CR; Yang, X	1
Hiraishi, K; Hu, YP; Inoue, R; Jian, YW; Koga, K; Kojima, D; Kurahara, LH; Onitsuka, M; Sumiyoshi, M; Takedatsu, H; Yue, L	1
Atreya, R; Baum, P; Carlé, B; Claussen, J; Ekici, AB; Friedrich, O; Kersten, C; Klimowicz, AC; Knieling, F; Kollias, G; Mbow, ML; Meyer, S; Neufert, C; Neurath, MF; Primbs, T; Rath, T; Raymond, EL; Scheibe, K; Schmied, A; Schürmann, S; Vieth, M; Waldner, MJ; Wirtz, S; Zheng, J	1
Burkly, LC; Dohi, T; Hagiwara, T; Inagaki-Ohara, K; Iseki, M; Kawamura, YI; Okada, T; Oshio, T; Son, A; Takaki, S; Wu, P; Yamazaki, M	1
Bondada, S; Bunnett, N; Cattaruzza, F; Cedron, W; Cevikbas, F; Grady, E; Johnson, C; Kirkwood, KS; Kirkwood, R; Leggit, A; Malone, B; Schenk, AK; Steinhoff, M	1
Chen, C; Gao, J; Han, W; Hu, G; Lu, H; Qian, L; Shen, J; Wan, R; Wang, X; Wu, M; Yu, Y; Zhu, S	1
Akbari, H; Flynn, RS; Grider, JR; Kellum, JM; Kuemmerle, JF; Li, C; Murthy, KS	1
Gaudio, E; Latella, G; Sferra, R; Speca, S; Vetuschi, A	1
Gong, YY; Heng, D; Li, P; Liang, ML; Lin, L; Wang, Y; Zhu, Y	1
Aziz, M; Bôle-Feysot, C; Déchelotte, P; Guerin, C; Loeuillard, E; Marion-Letellier, R; Melchior, C; Mulder, P; Nicol, L; Savoye, G; Savoye-Collet, C; Vera, P	1
Cao, LY; Ding, H; Fan, WJ; Gan, HZ; Mei, Q; Xu, JM	1
Adler, J; Dillman, JR; Higgins, PD; Johnson, LA; Moons, DS; Stidham, RW; Swanson, SD	1
Aziz, M; Bertrand, J; Coëffier, M; Déchelotte, P; Guérin, C; Herranen, A; Loeuillard, E; Marion-Letellier, R; Melchior, C; Savoye, G	1
Baird, AC; Lawrance, IC; Lloyd, F	1
Fujiya, M; Ikuta, K; Inaba, Y; Kashima, S; Kohgo, Y; Konishi, H; Moriichi, K; Ohtake, T; Tanabe, H; Ueno, N	1
Li, G; Ren, J; Tao, Q; Wang, B; Zheng, Y	1
Abe, J; Higashi, K; Hirano, K; Hozumi, K; Imai, J; Inagaki, Y; Mine, T; Sumiyoshi, H; Yazawa, M	1
Caruso, R; Colantoni, A; Di Fusco, D; Dinallo, V; Franzè, E; Izzo, R; Marafini, I; Monteleone, G; Monteleone, I; Pallone, F; Zorzi, F	1
Jing, M; Liu, JJ; Liu, X; Liu, XF; Lu, NH; Ren, CZ; Zhang, YX; Zhao, HQ	1
Fichtner-Feigl, S; Geissler, EK; Kitani, A; Schlitt, HJ; Strober, W; Young, CA	1
Caprilli, R; Catitti, V; D'Angelo, A; Flanders, KC; Gaudio, E; Latella, G; Sferra, R; Vetuschi, A; Zanninelli, G	1
Bai, Y; Gao, J; Li, Z; Wu, W; Zhang, W; Zhao, T; Zou, D	1
Bai, A; Guan, Q; Hillman, CL; Ma, A; Ma, Y; Peng, Z; Qing, G; Weiss, CR; Zhou, G	1
Cooney, RN; Fitzpatrick, LR; Koltun, WA; Meirelles, K; Puleo, FJ; Small, JS	1
Flier, SN; Kalluri, R; Kokkotou, EG; Sugimoto, H; Tanjore, H; Zeisberg, M	1
Crespo, I; González-Gallego, J; Kretzmann, NA; Marroni, N; Mauriz, JL; San-Miguel, B; Tuñón, MJ	1
Flynn, RS; Grider, JR; Hazelgrove, KB; Kuemmerle, JF; Mahavadi, S; Murthy, KS; Qiao, LY	1
Fazelbhoy, Z; Gerard, N; Hing, T; Karagiannides, I; Koon, HW; Lu, B; Pothoulakis, C; Shih, D; Xu, H; Zhao, D	1
Chen, HH; Li, XC; Lu, XL	1
Bai, A; Bernstein, CN; Guan, Q; Hillman, CL; Ma, AG; Ma, Y; Peng, Z; Qing, G; Warrington, RJ; Weiss, CR; Zhou, G	1
Peterson, MR; Peterson, TC; Raoul, JM	1
Kang, J; Patterson, AK	1
Higgins, PD; Johnson, LA; Kim, K; McKenna, BJ; Moons, DS; Rubin, JM; Stidham, RW; Xu, J	1
Fukumoto, K; Handa, O; Harusato, A; Hayashi, N; Hirai, Y; Hirata, I; Horie, R; Ichikawa, H; Inoue, K; Ishikawa, T; Kokura, S; Konishi, H; Mizushima, K; Naito, Y; Omatsu, T; Takagi, T; Uchiyama, K; Wakabayashi, N; Yagi, N; Yamada, S; Yoshida, N; Yoshikawa, T	1
Gillespie, BW; Govani, SM; Higgins, PD; Johnson, LA; Joyce, JC; Waljee, AK	1
Goldin, E; Israeli, E; Latella, G; Lysy, J; Metanes, I; Necozione, S; Papo, O; Pines, M; Wengrower, D; Zanninelli, G	1
Dai, W; Guo, C; He, S; Hu, G; Ni, J; Shen, J; Wan, R; Wang, F; Wang, X; Xiong, J; Xu, L; Yang, L	1
Chen, WX; Lu, YM; Ou, YX; Zhang, HZ; Zhu, MY	1
Blue, RE; Ding, S; Lund, PK; Macnaughton, K; Magness, ST; McNaughton, K; Walton, KL	1
Chandrasekaran, VR; Hsu, DZ; Liu, MY; Periasamy, S	1
Chakravarti, S; Fiocchi, C; Lawrance, IC; Leite, AZ; West, GA; Willis, J; Wu, F	1
Macdonald, TT	1
Dong, Y; Wang, XP; Wu, K; Wu, L; Zhang, R	1
Akay, C; Comert, B; Deveci, S; Inal, V; Isik, AT; Mas, MR; Mas, N; Tasci, I; Yamanel, L	2
Cai, JT; Du, Q; Gao, ZQ; Qian, KD; Wang, CH; Xie, CG; Ye, B	1
Fichtner-Feigl, S; Fuss, IJ; Geissler, EK; Kitani, A; Schlitt, HJ; Strober, W; Watanabe, T; Young, CA	1
Appelbee, A; Forrest, CH; Jooste, JC; Klopcic, B; Lawrance, IC; Lloyd, F; Raye, W	1
Higgins, PD; Jia, C; Johnson, LA; Joyce, JC; Kim, K; Rangwalla, S; Rubin, JM	1
Caprilli, R; Catitti, V; D'Angelo, A; Gaudio, E; Latella, G; Sferra, R; Vetuschi, A; Zanninelli, G	1
Buch, E; Bulbena, O; Fernández, C; Hinojosa, J; Lledó, S; Navarro, C	1
Dayan, D; Eyal, A; Rabau, M	1
Apte, MV; Crawford, DH; Haber, PS; Keogh, GW; McCaughan, GW; Moran, CS; Pirola, RC; Ramm, GA; Stewart, NL; Wilson, JS	1

Other Studies

65 other study(ies) available for trinitrobenzenesulfonic acid and Cirrhosis

Article	Year
CD147 Targeting by AC-73 Induces Autophagy and Reduces Intestinal Fibrosis Associated with TNBS Chronic Colitis. Journal of Crohn's & colitis, 2022, Nov-23, Volume: 16, Issue:11 Topics: Animals; Autophagy; Basigin; Colitis; Collagen; Colon; Disease Models, Animal; Ethanol; Fibrosis; Mice; Phenols; RNA, Messenger; Transforming Growth Factor beta1; Trinitrobenzenesulfonic Acid	2022
Elafin Reverses Intestinal Fibrosis by Inhibiting Cathepsin S-Mediated Protease-Activated Receptor 2. Cellular and molecular gastroenterology and hepatology, 2022, Volume: 14, Issue:4 Topics: Animals; Cathepsins; Collagen; Constriction, Pathologic; Crohn Disease; Elafin; Fibrosis; Humans; Intestinal Obstruction; Intestines; Mice; Peptide Hydrolases; Polymethacrylic Acids; Protease Inhibitors; Proteome; Receptor, PAR-2; Trinitrobenzenesulfonic Acid; Zinc Finger E-box-Binding Homeobox 1	2022
Role of Interleukin-17 in Pathogenesis of Intestinal Fibrosis in Mice. Digestive diseases and sciences, 2020, Volume: 65, Issue:7 Topics: Animals; Collagen Type III; Crohn Disease; Disease Models, Animal; Female; Fibrosis; Immunoglobulin G; Interleukin-17; Interleukin-1beta; Intestinal Mucosa; Intestines; Matrix Metalloproteinase 2; Mice; Reverse Transcriptase Polymerase Chain Reaction; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta1; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha; Up-Regulation	2020
Andrographolide sulfonate ameliorates chronic colitis induced by TNBS in mice via decreasing inflammation and fibrosis. International immunopharmacology, 2020, Volume: 83 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Colon; Colonic Diseases; Cytokines; Disease Models, Animal; Diterpenes; Epithelium; Female; Fibrosis; Inflammation; Injections, Intraperitoneal; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; NF-kappa B; T-Lymphocyte Subsets; Trinitrobenzenesulfonic Acid	2020
Betulinic acid hydroxamate prevents colonic inflammation and fibrosis in murine models of inflammatory bowel disease. Acta pharmacologica Sinica, 2021, Volume: 42, Issue:7 Topics: Animals; Anti-Inflammatory Agents; Betulinic Acid; Caco-2 Cells; Colon; Dextran Sulfate; Fibrosis; Gastrointestinal Agents; Gene Expression; Humans; Hydroxamic Acids; Inflammation; Inflammatory Bowel Diseases; Intestinal Mucosa; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; NIH 3T3 Cells; Pentacyclic Triterpenes; Trinitrobenzenesulfonic Acid	2021
Mycobacterial Hsp65 antigen delivered by invasive Lactococcus lactis reduces intestinal inflammation and fibrosis in TNBS-induced chronic colitis model. Scientific reports, 2020, 11-18, Volume: 10, Issue:1 Topics: Animals; Bacterial Proteins; Chaperonin 60; Colitis; Cytokines; Disease Models, Animal; Female; Fibrosis; Immunoglobulin A; Lactococcus lactis; Mice, Inbred BALB C; Microorganisms, Genetically-Modified; Trinitrobenzenesulfonic Acid	2020
Dietary salt exacerbates intestinal fibrosis in chronic TNBS colitis via fibroblasts activation. Scientific reports, 2021, 07-23, Volume: 11, Issue:1 Topics: Animals; Colitis; Diet; Disease Models, Animal; Extracellular Matrix Proteins; Fibroblasts; Fibrosis; Humans; Inflammation; Inflammatory Bowel Diseases; Intestinal Mucosa; Intestines; Myofibroblasts; Rats; Salts; Trinitrobenzenesulfonic Acid	2021
NF-E2-Related Factor 2 Suppresses Intestinal Fibrosis by Inhibiting Reactive Oxygen Species-Dependent TGF-β1/SMADs Pathway. Digestive diseases and sciences, 2018, Volume: 63, Issue:2 Topics: Animals; Cell Line; Colitis; Female; Fibroblasts; Fibrosis; Gene Expression Regulation; Humans; Hydroquinones; Mice; Mice, Inbred BALB C; NF-E2-Related Factor 2; Reactive Oxygen Species; Signal Transduction; Smad Proteins; Transforming Growth Factor beta1; Trinitrobenzenesulfonic Acid	2018
CD16+ Macrophages Mediate Fibrosis in Inflammatory Bowel Disease. Journal of Crohn's & colitis, 2018, Apr-27, Volume: 12, Issue:5 Topics: Adolescent; Adult; Animals; Cell Count; Cells, Cultured; Colitis; Colon; Colonic Neoplasms; Crohn Disease; Female; Fibrosis; Humans; Interleukin-4; Intestinal Mucosa; Lectins, C-Type; Macrophages; Male; Mannose Receptor; Mannose-Binding Lectins; Mice; Mice, Inbred BALB C; Mice, Knockout; Proto-Oncogene Proteins; Receptors, Cell Surface; Receptors, IgG; STAT6 Transcription Factor; Trinitrobenzenesulfonic Acid; Wnt Proteins; Young Adult	2018
Neuronal Transforming Growth Factor beta Signaling via SMAD3 Contributes to Pain in Animal Models of Chronic Pancreatitis. Gastroenterology, 2018, Volume: 154, Issue:8 Topics: Animals; Ceruletide; Disease Models, Animal; Fibrosis; Humans; Hyperalgesia; Male; Mice; Mice, Transgenic; Nociceptors; Pain; Pancreas; Pancreatitis, Chronic; Patch-Clamp Techniques; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Recombinant Proteins; Signal Transduction; Smad3 Protein; Synaptic Potentials; Transforming Growth Factor beta; Trinitrobenzenesulfonic Acid	2018
Knockdown of Smad7 With a Specific Antisense Oligonucleotide Attenuates Colitis and Colitis-Driven Colonic Fibrosis in Mice. Inflammatory bowel diseases, 2018, 05-18, Volume: 24, Issue:6 Topics: Animals; Colitis; Collagen Type I; Colon; Crohn Disease; Disease Models, Animal; Down-Regulation; Female; Fibrosis; Gene Knockdown Techniques; Mice; Mice, Inbred BALB C; Oligonucleotides; Oligonucleotides, Antisense; Signal Transduction; Smad3 Protein; Smad7 Protein; Transforming Growth Factor beta1; Trinitrobenzenesulfonic Acid	2018
Anti-fibrogenic Potential of Mesenchymal Stromal Cells in Treating Fibrosis in Crohn's Disease. Digestive diseases and sciences, 2018, Volume: 63, Issue:7 Topics: Animals; Cells, Cultured; Colon; Crohn Disease; Disease Models, Animal; Epithelial-Mesenchymal Transition; Fibrosis; Gene Expression Regulation; Interleukins; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice, Inbred BALB C; Phenotype; Phosphorylation; Signal Transduction; Smad2 Protein; Smad3 Protein; Stem Cell Niche; Time Factors; Transforming Growth Factor beta; Trinitrobenzenesulfonic Acid	2018
Reversing Ongoing Chronic Intestinal Inflammation and Fibrosis by Sustained Block of IL-12 and IL-23 Using a Vaccine in Mice. Inflammatory bowel diseases, 2018, 08-16, Volume: 24, Issue:9 Topics: Animals; Chronic Disease; Colitis; Dextran Sulfate; Disease Models, Animal; Female; Fibrosis; Interleukin-12 Subunit p40; Interleukin-23; Intestines; Mice; Mice, Inbred BALB C; Trinitrobenzenesulfonic Acid; Vaccines, Subunit	2018
Daikenchuto (Da-Jian-Zhong-Tang) ameliorates intestinal fibrosis by activating myofibroblast transient receptor potential ankyrin 1 channel. World journal of gastroenterology, 2018, Sep-21, Volume: 24, Issue:35 Topics: Adult; Animals; Cell Line; Chronic Disease; Colitis; Colon; Crohn Disease; Disease Models, Animal; Fibrosis; Humans; Male; Mice; Mice, Knockout; Middle Aged; Myofibroblasts; Panax; Plant Extracts; Trinitrobenzenesulfonic Acid; TRPA1 Cation Channel; Zanthoxylum; Zingiberaceae	2018
Inhibiting Interleukin 36 Receptor Signaling Reduces Fibrosis in Mice With Chronic Intestinal Inflammation. Gastroenterology, 2019, Volume: 156, Issue:4 Topics: Actins; Animals; Antibodies, Neutralizing; Case-Control Studies; Cells, Cultured; Colitis; Colitis, Ulcerative; Collagen Type VI; Colon; Crohn Disease; Dextran Sulfate; Fibroblasts; Fibrosis; Gene Expression; Gene Expression Profiling; Humans; Interleukin-1; Intestinal Mucosa; Intestine, Small; Ligands; Mice; Mice, Knockout; Receptors, Interleukin-1; Signal Transduction; Transcriptome; Trinitrobenzenesulfonic Acid	2019
TWEAK/Fn14 pathway promotes a T helper 2-type chronic colitis with fibrosis in mice. Mucosal immunology, 2013, Volume: 6, Issue:6 Topics: Animals; Cell Proliferation; Cells, Cultured; Chronic Disease; Colitis; Colon; Cytokine TWEAK; Disease Models, Animal; Female; Fibroblasts; Fibrosis; Humans; Immunoglobulins; Interleukin-13; Mice; Mice, Inbred BALB C; Mice, Knockout; Organ Culture Techniques; Receptors, Cytokine; Receptors, Tumor Necrosis Factor; Th2 Cells; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factors; TWEAK Receptor	2013
Transient receptor potential ankyrin 1 mediates chronic pancreatitis pain in mice. American journal of physiology. Gastrointestinal and liver physiology, 2013, Jun-01, Volume: 304, Issue:11 Topics: Animals; Central Nervous System Sensitization; Disease Models, Animal; Fibrosis; Inflammation; Injury Severity Score; Locomotion; Mice; Mice, Inbred C57BL; Mice, Knockout; Pancreatitis, Chronic; Transient Receptor Potential Channels; Trinitrobenzenesulfonic Acid; TRPA1 Cation Channel; Visceral Pain	2013
Antifibrotic role of chemokine CXCL9 in experimental chronic pancreatitis induced by trinitrobenzene sulfonic acid in rats. Cytokine, 2013, Volume: 64, Issue:1 Topics: Animals; Antibodies, Neutralizing; Cell Proliferation; Chemokine CXCL9; Collagen Type I; Fibrosis; Hydroxyproline; Male; Pancreas; Pancreatic Stellate Cells; Pancreatitis, Chronic; Rats; Rats, Sprague-Dawley; Receptors, CXCR3; Transforming Growth Factor beta1; Trinitrobenzenesulfonic Acid	2013
Increased activation of latent TGF-β1 by αVβ3 in human Crohn's disease and fibrosis in TNBS colitis can be prevented by cilengitide. Inflammatory bowel diseases, 2013, Volume: 19, Issue:13 Topics: Adult; Animals; Blotting, Western; Cells, Cultured; Colon; Crohn Disease; Cytokines; Enzyme-Linked Immunosorbent Assay; Female; Fibrosis; Fluorescent Antibody Technique; Humans; Integrin alphaVbeta3; Intestinal Mucosa; Intestines; Male; Middle Aged; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Snake Venoms; Transforming Growth Factor beta1; Trinitrobenzenesulfonic Acid; Young Adult	2013
Localization of ανβ6 integrin-TGF-β1/Smad3, mTOR and PPARγ in experimental colorectal fibrosis. European journal of histochemistry : EJH, 2013, Dec-04, Volume: 57, Issue:4 Topics: Actins; Animals; Antigens, Neoplasm; Colon; Fibrosis; Integrins; Mice; PPAR gamma; Signal Transduction; Smad3 Protein; TOR Serine-Threonine Kinases; Transforming Growth Factor beta1; Trinitrobenzenesulfonic Acid	2013
Resveratrol inhibits collagen I synthesis by suppressing IGF-1R activation in intestinal fibroblasts. World journal of gastroenterology, 2014, Apr-28, Volume: 20, Issue:16 Topics: Animals; Cell Line; Colitis; Collagen Type I; Colon; Disease Models, Animal; Down-Regulation; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Fibrosis; Insulin-Like Growth Factor I; Male; MAP Kinase Kinase Kinases; Mice; Mutation; Phosphorylation; Rats, Sprague-Dawley; Receptor, IGF Type 1; Resveratrol; RNA Interference; RNA, Messenger; Signal Transduction; Sirtuin 1; Stilbenes; Transfection; Trinitrobenzenesulfonic Acid	2014
Magnetic resonance colonography for fibrosis assessment in rats with chronic colitis. PloS one, 2014, Volume: 9, Issue:7 Topics: Animals; Chronic Disease; Colitis; Colonoscopy; Constriction, Pathologic; Feasibility Studies; Fibrosis; Magnetic Resonance Imaging; Male; Rats; Rats, Sprague-Dawley; Trinitrobenzenesulfonic Acid	2014
Homocysteine promotes intestinal fibrosis in rats with trinitrobenzene sulfonic acid-induced colitis. Digestive diseases and sciences, 2015, Volume: 60, Issue:2 Topics: Animals; Colitis; Collagen Type I; Collagen Type III; Colon; Cytokines; Disease Models, Animal; Ethanol; Fibrosis; Homocysteine; Hyperhomocysteinemia; Inflammation Mediators; Intestinal Mucosa; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Rats, Sprague-Dawley; Trinitrobenzenesulfonic Acid	2015
Comparison of noncontrast MRI magnetization transfer and T2 -Weighted signal intensity ratios for detection of bowel wall fibrosis in a Crohn's disease animal model. Journal of magnetic resonance imaging : JMRI, 2015, Volume: 42, Issue:3 Topics: Animals; Collagen; Colon; Crohn Disease; Disease Models, Animal; Fibrosis; Inflammation; Intestinal Mucosa; Intestines; Magnetic Resonance Imaging; Rats; Rats, Inbred Lew; ROC Curve; Sensitivity and Specificity; Signal Processing, Computer-Assisted; Trinitrobenzenesulfonic Acid	2015
2,4,6-trinitrobenzene sulfonic acid-induced chronic colitis with fibrosis and modulation of TGF-β1 signaling. World journal of gastroenterology, 2014, Dec-28, Volume: 20, Issue:48 Topics: Animals; Boronic Acids; Bortezomib; Chronic Disease; Colitis; Colon; Disease Models, Animal; Fibrosis; Male; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Rats, Sprague-Dawley; Signal Transduction; Tight Junction Proteins; Transforming Growth Factor beta1; Trinitrobenzenesulfonic Acid	2014
Prostaglandin E₂ and polyenylphosphatidylcholine protect against intestinal fibrosis and regulate myofibroblast function. Digestive diseases and sciences, 2015, Volume: 60, Issue:6 Topics: Animals; Biomarkers; Cytokines; Dinoprostone; Disease Models, Animal; Female; Fibrosis; Gene Expression; Humans; Immunoenzyme Techniques; Inflammatory Bowel Diseases; Mice; Mice, Inbred C57BL; Myofibroblasts; Phosphatidylcholines; Real-Time Polymerase Chain Reaction; Trinitrobenzenesulfonic Acid	2015
Polyphosphate, an active molecule derived from probiotic Lactobacillus brevis, improves the fibrosis in murine colitis. Translational research : the journal of laboratory and clinical medicine, 2015, Volume: 166, Issue:2 Topics: Animals; Caco-2 Cells; Chronic Disease; Colitis; Collagen; Colon; Connective Tissue Growth Factor; Cytokines; Dextran Sulfate; Epithelial Cells; Fibrosis; Humans; Inflammation; Inflammation Mediators; Levilactobacillus brevis; Macrophages; Mice, Inbred C57BL; Polyphosphates; Probiotics; Transforming Growth Factor beta1; Trinitrobenzenesulfonic Acid; Up-Regulation	2015
Triptolide ameliorates colonic fibrosis in an experimental rat model. Molecular medicine reports, 2015, Volume: 12, Issue:2 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Collagen; Collagen Type I; Colon; Diterpenes; Epoxy Compounds; Extracellular Matrix; Fibrosis; Male; Myofibroblasts; Phenanthrenes; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Trinitrobenzenesulfonic Acid	2015
Anti-fibrotic effects of a novel small compound on the regulation of cytokine production in a mouse model of colorectal fibrosis. Biochemical and biophysical research communications, 2015, Dec-25, Volume: 468, Issue:4 Topics: Alkadienes; Animals; Anti-Inflammatory Agents; Colitis; Colon; Cytokines; Female; Fibrosis; Mice; Mice, Inbred BALB C; Treatment Outcome; Trinitrobenzenesulfonic Acid	2015
Aryl hydrocarbon receptor-driven signals inhibit collagen synthesis in the gut. European journal of immunology, 2016, Volume: 46, Issue:4 Topics: Actins; Adult; Aged; Animals; Azo Compounds; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type III; Constriction, Pathologic; Crohn Disease; Extracellular Signal-Regulated MAP Kinases; Female; Fibroblasts; Fibrosis; Gastrointestinal Tract; Humans; Mice; Mice, Inbred BALB C; Middle Aged; p38 Mitogen-Activated Protein Kinases; Pyrazoles; Receptors, Aryl Hydrocarbon; Transforming Growth Factor beta1; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha	2016
The pharmacodynamic active components study of Tibetan medicine Gentianopsis paludosa on ulcerative colitis fibrosis. International immunopharmacology, 2017, Volume: 46 Topics: Animals; Cells, Cultured; China; Colitis, Ulcerative; Colon; Ethanol; Fibrosis; Gentianaceae; Humans; Medicine, Tibetan Traditional; Plant Extracts; Rats; Rats, Wistar; Trinitrobenzenesulfonic Acid; Xanthones	2017
IL-13 signaling via IL-13R alpha2 induces major downstream fibrogenic factors mediating fibrosis in chronic TNBS colitis. Gastroenterology, 2008, Volume: 135, Issue:6 Topics: Animals; Apoptosis; Blotting, Western; Cells, Cultured; Colitis; Colon; Disease Models, Animal; Early Growth Response Protein 1; Enzyme-Linked Immunosorbent Assay; Female; Fibroblasts; Fibrosis; Gene Expression Regulation; Insulin-Like Growth Factor I; Interleukin-13; Interleukin-13 Receptor alpha2 Subunit; Mice; Mice, Inbred BALB C; Polymerase Chain Reaction; RNA; Signal Transduction; Transforming Growth Factor beta1; Trinitrobenzenesulfonic Acid; Zinc Fingers	2008
Smad3 loss confers resistance to the development of trinitrobenzene sulfonic acid-induced colorectal fibrosis. European journal of clinical investigation, 2009, Volume: 39, Issue:2 Topics: Animals; Collagen; Colon; Connective Tissue Growth Factor; Female; Fibrosis; Male; Mice; Mice, Knockout; Rectum; Smad3 Protein; Smad7 Protein; Transforming Growth Factor beta; Trinitrobenzenesulfonic Acid	2009
High-dose naproxen aggravates pancreatic fibrosis in a rat model of chronic pancreatitis. Pancreas, 2010, Volume: 39, Issue:3 Topics: Actins; Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Fibrosis; Male; Naproxen; Pain; Pancreatitis, Chronic; Rats; Rats, Sprague-Dawley; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha	2010
Targeting TGF-beta1 by employing a vaccine ameliorates fibrosis in a mouse model of chronic colitis. Inflammatory bowel diseases, 2010, Volume: 16, Issue:6 Topics: Animals; CD4-Positive T-Lymphocytes; Chronic Disease; Colitis; Female; Fibrosis; Immunoglobulin G; Interleukin-17; Interleukin-23; Lymph Nodes; Mesentery; Mice; Mice, Inbred BALB C; Phosphorylation; Smad3 Protein; Transforming Growth Factor beta1; Trinitrobenzenesulfonic Acid; Vaccines, Synthetic	2010
A new model of chronic hapten-induced colitis in young rats. Journal of pediatric gastroenterology and nutrition, 2010, Volume: 50, Issue:3 Topics: Animals; Chronic Disease; Colitis; Colon; Cytokines; Disease Models, Animal; Fibrosis; Haptens; Inflammation Mediators; Organ Size; Rats; Rats, Wistar; Severity of Illness Index; Trinitrobenzenesulfonic Acid; Ulcer	2010
Identification of epithelial to mesenchymal transition as a novel source of fibroblasts in intestinal fibrosis. The Journal of biological chemistry, 2010, Jun-25, Volume: 285, Issue:26 Topics: Animals; beta-Galactosidase; Bone Morphogenetic Protein 7; Cadherins; Cell Line; Cells, Cultured; Colitis; Colon; Epithelial Cells; Female; Fibroblasts; Fibrosis; Humans; Inflammatory Bowel Diseases; Intercellular Signaling Peptides and Proteins; Intestinal Mucosa; Intestines; Lac Operon; Male; Mesoderm; Mice; Mice, Inbred C57BL; Mice, Transgenic; Proteins; Transforming Growth Factor beta1; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha	2010
Glutamine prevents fibrosis development in rats with colitis induced by 2,4,6-trinitrobenzene sulfonic acid. The Journal of nutrition, 2010, Volume: 140, Issue:6 Topics: Animals; Colitis; Fibrosis; Gene Expression Regulation; Glutamine; Inflammation; Interleukin-6; Male; Rats; Rats, Wistar; RNA, Messenger; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha	2010
Amelioration of excess collagen IαI, fibrosis, and smooth muscle growth in TNBS-induced colitis in IGF-I(+/-) mice. Inflammatory bowel diseases, 2011, Volume: 17, Issue:3 Topics: Animals; Apoptosis; Blotting, Western; Cells, Cultured; Colitis; Collagen Type I; Collagen Type I, alpha 1 Chain; Enzyme-Linked Immunosorbent Assay; Fibrosis; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor Binding Protein 5; Insulin-Like Growth Factor I; Intestines; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transforming Growth Factor beta1; Trinitrobenzenesulfonic Acid	2011
Substance P modulates colitis-associated fibrosis. The American journal of pathology, 2010, Volume: 177, Issue:5 Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Cell Movement; Colitis; Collagen; Colon; Fibroblasts; Fibrosis; Humans; Insulin-Like Growth Factor I; Intestinal Mucosa; Mice; Mice, Knockout; Neurokinin-1 Receptor Antagonists; Proto-Oncogene Proteins c-akt; Receptors, Neurokinin-1; Substance P; Transforming Growth Factor beta1; Trinitrobenzenesulfonic Acid; Vimentin	2010
α-Tocopherol treatment ameliorates chronic pancreatitis in an experimental rat model induced by trinitrobenzene sulfonic acid. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2011, Volume: 11, Issue:1 Topics: Administration, Oral; alpha-Tocopherol; Animals; Antioxidants; Body Weight; Disease Models, Animal; Disease-Free Survival; Fibrosis; Kaplan-Meier Estimate; Longevity; Male; Organ Size; Pancreas; Pancreatic Pseudocyst; Pancreatitis, Chronic; Rats; Rats, Sprague-Dawley; Trinitrobenzenesulfonic Acid	2011
Targeting IL-12/IL-23 by employing a p40 peptide-based vaccine ameliorates TNBS-induced acute and chronic murine colitis. Molecular medicine (Cambridge, Mass.), 2011, Volume: 17, Issue:7-8 Topics: Acute Disease; Animals; Chronic Disease; Colitis; Collagen; Colon; Cytokines; Enzyme-Linked Immunosorbent Assay; Female; Fibrosis; Gene Expression; Immunoglobulin G; Interleukin-12 Subunit p40; Lymph Nodes; Mesentery; Mice; Mice, Inbred BALB C; Nitric Oxide Synthase Type II; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; Th1 Cells; Th17 Cells; Trinitrobenzenesulfonic Acid; Vaccines, Subunit; Weight Loss	2011
The effect of pentoxifylline and its metabolite-1 on inflammation and fibrosis in the TNBS model of colitis. European journal of pharmacology, 2011, Jul-15, Volume: 662, Issue:1-3 Topics: Animals; Colitis; Collagen Type I; Colon; Disease Models, Animal; Female; Fibrosis; Inflammation; Interleukin-18; Intestinal Mucosa; Intestines; Organ Size; Pentoxifylline; Peroxidase; Rats; Rats, Sprague-Dawley; Stereoisomerism; Time Factors; Trinitrobenzenesulfonic Acid	2011
Principal component analysis of mRNA levels of genes related to inflammation and fibrosis in rats treated with TNBS or glutamine. Inflammatory bowel diseases, 2011, Volume: 17, Issue:7 Topics: Animals; Biomarkers; Fibrosis; Gene Expression Regulation; Glutamine; Inflammation; Principal Component Analysis; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Trinitrobenzenesulfonic Acid	2011
Ultrasound elasticity imaging for detecting intestinal fibrosis and inflammation in rats and humans with Crohn's disease. Gastroenterology, 2011, Volume: 141, Issue:3 Topics: Animals; Biomechanical Phenomena; Colitis; Colon; Crohn Disease; Diagnosis, Differential; Diagnostic Imaging; Disease Models, Animal; Disease Progression; Elasticity; Female; Fibrosis; Humans; Inflammation; Inflammatory Bowel Diseases; Intestine, Small; Pilot Projects; Rats; Rats, Inbred Lew; Trinitrobenzenesulfonic Acid; Ultrasonography	2011
Daikenchuto, a Kampo medicine, regulates intestinal fibrosis associated with decreasing expression of heat shock protein 47 and collagen content in a rat colitis model. Biological & pharmaceutical bulletin, 2011, Volume: 34, Issue:11 Topics: Animals; Colitis; Collagen Type I; Colon; Disease Models, Animal; Fibrosis; Gastrointestinal Agents; HSP47 Heat-Shock Proteins; Intestinal Mucosa; Male; Medicine, Kampo; Panax; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; RNA, Messenger; Transforming Growth Factor beta1; Trinitrobenzenesulfonic Acid; Ulcer; Zanthoxylum; Zingiberaceae	2011
Spironolactone and colitis: increased mortality in rodents and in humans. Inflammatory bowel diseases, 2012, Volume: 18, Issue:7 Topics: Animals; Clostridioides difficile; Clostridium Infections; Colitis; Crohn Disease; Female; Fibrosis; Hospitalization; Humans; Inflammation; Intestinal Diseases; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Myofibroblasts; Rats; Retrospective Studies; Spironolactone; Survival Rate; Transforming Growth Factor beta; Trinitrobenzenesulfonic Acid	2012
Losartan reduces trinitrobenzene sulphonic acid-induced colorectal fibrosis in rats. Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 2012, Volume: 26, Issue:1 Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Colitis; Disease Models, Animal; Disease Progression; Down-Regulation; Fibrosis; Intestinal Mucosa; Losartan; Male; Rats; Transforming Growth Factor beta1; Trinitrobenzenesulfonic Acid	2012
L-cysteine administration attenuates pancreatic fibrosis induced by TNBS in rats by inhibiting the activation of pancreatic stellate cell. PloS one, 2012, Volume: 7, Issue:2 Topics: Animals; Cysteine; Fibrosis; Pancreatic Diseases; Pancreatic Stellate Cells; Pancreatitis, Chronic; Rats; Treatment Outcome; Trinitrobenzenesulfonic Acid	2012
Dynamic progress of 2,4,6-trinitrobenzene sulfonic acid induced chronic colitis and fibrosis in rat model. Journal of digestive diseases, 2012, Volume: 13, Issue:8 Topics: Analysis of Variance; Animals; Chronic Disease; Colitis; Collagen Type I; Collagen Type III; Colon; Connective Tissue Growth Factor; Cytokines; Female; Fibrosis; Gene Expression; Interleukin-13; Interleukin-17; Interleukin-2; Interleukin-4; Rats; Rats, Sprague-Dawley; RNA, Messenger; Smad3 Protein; Time Factors; Transforming Growth Factor beta1; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha	2012
Mucosal healing and fibrosis after acute or chronic inflammation in wild type FVB-N mice and C57BL6 procollagen α1(I)-promoter-GFP reporter mice. PloS one, 2012, Volume: 7, Issue:8 Topics: Acute Disease; Animals; Antigens; Chronic Disease; Collagen Type I; Collagen Type I, alpha 1 Chain; Colon; Dextran Sulfate; Disease Models, Animal; Female; Fibrosis; Genes, Reporter; Green Fluorescent Proteins; Inflammation; Intestinal Mucosa; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myofibroblasts; Promoter Regions, Genetic; Survival Analysis; Trinitrobenzenesulfonic Acid; Vimentin; Weight Loss; Wound Healing	2012
Sesame oil accelerates healing of 2,4,6-trinitrobenzenesulfonic acid-induced acute colitis by attenuating inflammation and fibrosis. JPEN. Journal of parenteral and enteral nutrition, 2013, Volume: 37, Issue:5 Topics: Acute Disease; Animals; Colitis; Colon; Disease Models, Animal; Fibrosis; Inflammation; Male; Organ Size; Rats; Rats, Wistar; Sesame Oil; Trinitrobenzenesulfonic Acid	2013
A murine model of chronic inflammation-induced intestinal fibrosis down-regulated by antisense NF-kappa B. Gastroenterology, 2003, Volume: 125, Issue:6 Topics: Animals; Chronic Disease; Colitis; Collagen; Colon; Disease Models, Animal; Female; Fibrosis; Interferon-gamma; Matrix Metalloproteinase 1; Mice; Mice, Inbred BALB C; NF-kappa B; Oligonucleotides, Antisense; RNA, Messenger; Transcription Factor RelA; Transforming Growth Factor beta; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha	2003
A mouse model of intestinal fibrosis? Gastroenterology, 2003, Volume: 125, Issue:6 Topics: Animals; Colitis; Colon; Disease Models, Animal; Fibrosis; Mice; NF-kappa B; Oligonucleotides, Antisense; Transcription Factor RelA; Trinitrobenzenesulfonic Acid	2003
Angiotensin II mediates acinar cell apoptosis during the development of rat pancreatic fibrosis by AT1R. Pancreas, 2004, Volume: 29, Issue:4 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Disease Models, Animal; Fibrosis; Gene Expression Regulation; In Situ Nick-End Labeling; Losartan; Male; Pancreas; Pancreatic Ducts; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Reverse Transcriptase Polymerase Chain Reaction; Trinitrobenzenesulfonic Acid	2004
Antioxidant treatment with taurine ameliorates chronic pancreatitis in an experimental rat model. Pancreas, 2006, Volume: 33, Issue:1 Topics: Animals; Antioxidants; Body Weight; Disease Models, Animal; Fibrosis; Glutathione Peroxidase; Male; Malondialdehyde; Oxidative Stress; Pancreatitis, Chronic; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Taurine; Trinitrobenzenesulfonic Acid	2006
[Effect of emodin on pancreatic fibrosis: experiment with rats]. Zhonghua yi xue za zhi, 2006, Sep-26, Volume: 86, Issue:36 Topics: Animals; Blotting, Western; Collagen; Disease Models, Animal; Dose-Response Relationship, Drug; Emodin; Fibrosis; Hyaluronic Acid; Laminin; Male; Pancreas; Pancreatic Diseases; Phytotherapy; Radioimmunoassay; Random Allocation; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta; Trinitrobenzenesulfonic Acid	2006
Induction of IL-13 triggers TGF-beta1-dependent tissue fibrosis in chronic 2,4,6-trinitrobenzene sulfonic acid colitis. Journal of immunology (Baltimore, Md. : 1950), 2007, May-01, Volume: 178, Issue:9 Topics: Animals; Colitis; Fibrosis; Interferon-gamma; Interleukin-13; Interleukin-13 Receptor alpha2 Subunit; Interleukins; Mice; Mice, Inbred BALB C; Phosphorylation; Receptors, Interleukin-13; RNA, Small Interfering; Smad3 Protein; Smad7 Protein; Th1 Cells; Transforming Growth Factor beta1; Trinitrobenzenesulfonic Acid	2007
Indomethacin and retinoic acid modify mouse intestinal inflammation and fibrosis: a role for SPARC. Digestive diseases and sciences, 2008, Volume: 53, Issue:6 Topics: Animals; Crohn Disease; Disease Models, Animal; Female; Fibrosis; Immunoenzyme Techniques; Indomethacin; Mice; Osteonectin; Random Allocation; Reverse Transcriptase Polymerase Chain Reaction; RNA; Statistics, Nonparametric; Tretinoin; Trinitrobenzenesulfonic Acid	2008
Allopurinol in rat chronic pancreatitis: effects on pancreatic stellate cell activation. Pancreas, 2007, Volume: 35, Issue:4 Topics: Actins; Allopurinol; Animals; Antioxidants; Atrophy; Collagen; Disease Models, Animal; Enzyme Inhibitors; Fibrosis; Immunohistochemistry; Male; Oxidative Stress; Pancreas; Pancreatitis, Chronic; Rats; Rats, Sprague-Dawley; Time Factors; Trinitrobenzenesulfonic Acid; Xanthine Oxidase	2007
Noninvasive ultrasound elasticity imaging (UEI) of Crohn's disease: animal model. Ultrasound in medicine & biology, 2008, Volume: 34, Issue:6 Topics: Animals; Colon; Crohn Disease; Disease Models, Animal; Elasticity; Elasticity Imaging Techniques; Female; Fibrosis; Image Interpretation, Computer-Assisted; In Vitro Techniques; Rats; Rats, Inbred Lew; Sensitivity and Specificity; Stress, Mechanical; Trinitrobenzenesulfonic Acid	2008
Prevention of colonic fibrosis by Boswellia and Scutellaria extracts in rats with colitis induced by 2,4,5-trinitrobenzene sulphonic acid. European journal of clinical investigation, 2008, Volume: 38, Issue:6 Topics: Actins; Animals; Boswellia; CD3 Complex; Colitis; Collagen Type I; Collagen Type II; Collagen Type III; Colon; Connective Tissue Growth Factor; Crohn Disease; Fibrosis; Immediate-Early Proteins; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Male; Models, Animal; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Scutellaria; Smad3 Protein; Smad7 Protein; Transforming Growth Factor beta1; Trinitrobenzenesulfonic Acid	2008
Transmucosal potential difference in experimental colitis in rats. Inflammation, 1995, Volume: 19, Issue:4 Topics: Animals; Colitis; Colitis, Ulcerative; Fibrosis; Intestinal Mucosa; Leukotriene B4; Leukotrienes; Male; Membrane Potentials; Peroxidase; Rats; Rats, Wistar; Trinitrobenzenesulfonic Acid	1995
Histomorphometric evaluation of experimentally induced colitis with trinitrobenzene-sulphonic acid in rats. International journal of experimental pathology, 1996, Volume: 77, Issue:4 Topics: Acute Disease; Animals; Colitis; Colon; Disease Progression; Fibrosis; Inflammatory Bowel Diseases; Intestinal Mucosa; Male; Necrosis; Rats; Rats, Wistar; Time Factors; Trinitrobenzenesulfonic Acid	1996
Activation of pancreatic stellate cells in human and experimental pancreatic fibrosis. The American journal of pathology, 1999, Volume: 155, Issue:4 Topics: Actins; Animals; Chronic Disease; Collagen; Desmin; Disease Models, Animal; Fibrosis; Glial Fibrillary Acidic Protein; Humans; Immunohistochemistry; Male; Pancreas; Pancreatitis, Alcoholic; Procollagen; Rats; Receptor, Platelet-Derived Growth Factor beta; RNA, Messenger; Transforming Growth Factor beta; Trinitrobenzenesulfonic Acid	1999