trinitrobenzenesulfonic acid has been researched along with Allodynia in 49 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (2.04) | 18.2507 |
| 2000's | 16 (32.65) | 29.6817 |
| 2010's | 31 (63.27) | 24.3611 |
| 2020's | 1 (2.04) | 2.80 |
| Authors | Studies |
|---|---|
| Bai, Y; Chen, T; Fan, BY; Li, H; Li, JN; Li, YQ; Qiu, XT; Ren, D; Wan, FP; Wu, ZY; Zhang, MM | 1 |
| Bai, Y; Chen, T; Chen, YB; Fan, BY; Li, H; Li, YQ; Ma, LT; Qiu, XT; Ren, D; Sun, HK; Yi, XN; Zhang, MM; Zhang, T | 1 |
| Bai, Y; Chen, T; Chen, YB; Fan, BY; Li, H; Li, YQ; Ma, LT; Qiu, XT; Sun, HK; Zhang, MM; Zhang, T | 1 |
| Aguirre, JE; Sarna, SK; Winston, JH | 1 |
| Chen, L; Luo, D; Yu, B | 1 |
| Babygirija, R; Kannampalli, P; Miranda, A; Sengupta, JN; Sood, M | 1 |
| Li, Q; Liu, L; Noë, M; Pasricha, PJ; Zhu, Y | 1 |
| Cao, DL; Han, Y; Lu, Y; Zhang, YL; Zhao, LX | 1 |
| Brierley, SM; Castro, J; Deiteren, A; Feil, R; Garcia-Caraballo, S; Ge, P; Ghetti, A; Grundy, L; Hannig, G; Harrington, AM; Kurtz, CB; Maddern, J; Miller, P; Peters, S; Rychkov, GY; Silos-Santiago, I | 1 |
| Chen, LZ; He, W; Jing, XH; Kan, Y; Lv, PR; Shi, H; Su, YS; Wang, XY; Wu, QF; Yu, SG; Zhang, XN; Zhu, B | 1 |
| Bernier, SG; Bryant, AP; Bueno, L; Currie, MG; Eutamene, H; Ge, P; Graul, C; Hannig, G; Jacobson, S; Jin, H; Kessler, MM; Kurtz, CB; Liong, E; Pezzone, MA; Reza, T; Rivers, S; Shea, C; Silos-Santiago, I; Tchernychev, B; Ustinova, EE | 1 |
| Banerjee, B; Bruckert, M; Kannampalli, P; Pochiraju, S; Sengupta, JN; Shaker, R | 1 |
| Huang, LY; Li, Y; Song, DD; Tang, D; Yuan, YZ | 1 |
| De Man, JG; De Winter, BY; Deiteren, A; Moreels, TG; Pelckmans, PA; Vermeulen, W | 1 |
| Anderson, EM; Caudle, RM; Del Valle-Pinero, AY; Henderson, WA; Sherwin, LB | 1 |
| Hu, S; Jiang, X; Jin, Y; Liu, T; Wang, S; Xu, GY; Zhou, Y; Zhu, HY | 1 |
| Buckinx, R; Ceuleers, H; De Man, JG; De Winter, BY; de Wit, A; Deiteren, A; Moreels, TG; Pelckmans, PA; Timmermans, JP; van der Linden, L | 1 |
| Honda, K; Iwata, K; Katagiri, A; Maruno, M; Satoh-Kuriwada, S; Shinoda, M; Shoji, N; Takeda, M; Tsuchiya, M | 1 |
| Ashley Blackshaw, L; Brierley, SM; Campaniello, MA; Harrington, AM; Hughes, PA; Martin, CM | 1 |
| Dai, Y; Hao, Y; Kogure, Y; Nishiyama, N; Noguchi, K; Tanaka, K; Wang, S; Yamamoto, S | 1 |
| Bellucci, F; Buéno, L; Bugianesi, R; Crea, A; D'Aranno, V; Maggi, CA; Meini, S; Santicioli, P; Tramontana, M | 1 |
| Gao, L; Li, Y; Yang, J; Yu, Y; Zhen, Y; Zuo, X | 1 |
| Gebhart, GF; Greenwood-van Meerveld, B; Hicks, GA; Johnson, A; McLean, PG; Winchester, WJ | 1 |
| Agostini, S; Broccardo, M; Bueno, L; Eutamene, H; Improta, G; Petrella, C; Theodorou, V | 1 |
| Adam, B; Blackshaw, LA; Brierley, SM; Cooper, NJ; Corey, DP; Harrington, AM; Holtmann, G; Hughes, PA; Kwan, KY; Liebregts, T; Martin, CM; O'Donnell, TA; Page, AJ; Rychkov, GY | 1 |
| Beaufrand, C; Bradesi, S; Bryant, AP; Bueno, L; Cohen, M; Currie, MG; Eutamene, H; Fioramonti, J; Kurtz, C; Larauche, M; Mayer, EA; Ohning, G; Theodorou, V | 1 |
| Chen, ZY; Gao, L; Li, Y; Liu, C; Yang, J; Yu, H; Yu, Y; Zuo, X | 1 |
| Bento, AF; Chichorro, JG; Claudino, RF; Marcon, R; Rae, GA | 1 |
| Albers, KM; Feng, B; Gebhart, GF; Shinoda, M; Tanaka, T | 1 |
| Bai, Y; Gao, J; Li, Z; Wei, L; Wu, W; Zhang, W; Zhao, T; Zou, D | 1 |
| Colak, T; Li, C; Liu, L; Mehta, K; Pai, R; Pasricha, PJ; Shenoy, M; Zhu, Y | 1 |
| Chang, FY; Chen, CC; Hsieh, JC; Lee, HF; Lee, IH; Lee, SD; Lin, HC; Liu, PY; Lu, CL; Wang, CC | 1 |
| Annaházi, A; Bueno, L; Dabek, M; Eutamene, H; Gecse, K; Polizzi, A; Róka, R; Rosztóczy, A; Salvador-Cartier, C; Theodorou, V; Wittmann, T | 1 |
| Fan, F; Qing-Chuan, Z; Quan-Xin, F; Shi-Qi, W; Shu-Jun, L; Wei, W; Xiang-Ying, F; Xu-Jie, Z; Zhao-Xu, L | 1 |
| Bacquié, V; Bézirard, V; Braniste, V; Houdeau, E; Lencina, C; Lévêque, M; Ménard, S; Moussa, L; Salvador-Cartier, C; Théodorou, V | 1 |
| Adam, B; Bartholomeusz, FD; Holtmann, G; Liebregts, T; Tsopelas, C | 1 |
| Ardid, D; Eschalier, A; Etienne, M; Jourdan, D; Millecamps, M | 1 |
| Adam, B; Bechmann, L; Best, J; Holtmann, G; Koehler, S; Lackner, C; Liebregts, T; Neumann, J | 1 |
| Adam, B; Bertel, A; Gerken, G; Holtmann, G; Lackner, C; Liebregts, T; Neumann, J; Talley, NJ | 1 |
| Adam, B; Gschossmann, JM; Holtmann, G; Krippner, C; Liebregts, T; Ruwe, M; Scholl, F | 1 |
| Caudle, RM; Price, DD; Verne, GN; Zhou, Q | 2 |
| Pasricha, PJ; Pendyala, S; Shenoy, M; Winston, JH; Xu, GY; Yin, H | 1 |
| Banerjee, B; Mannem, A; Miranda, A; Nordstrom, E; Sengupta, JN; Smith, C | 1 |
| Kawai, M; Kurebayashi, Y; Ninomiya, N; Ohashi, K; Taylor, C | 1 |
| Brennan, TJ; Cameron, DM; Gebhart, GF | 1 |
| Kawai, M; Kurebayashi, Y; Ohashi, K; Sato, Y | 1 |
| Buéno, L; Coelho, AM; Fioramonti, J; Lacheze, C | 1 |
| Buéno, L; Coelho, AM; Fioramonti, J; Lecci, A; Maggi, C; Toulouse, M | 1 |
49 other study(ies) available for trinitrobenzenesulfonic acid and Allodynia
| Article | Year |
|---|---|
Anterior Cingulate Cortex Mediates Hyperalgesia and Anxiety Induced by Chronic Pancreatitis in Rats.
Topics: Animals; Anxiety; Chronic Pain; GABAergic Neurons; Gyrus Cinguli; Hyperalgesia; Pancreatitis, Chronic; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Trinitrobenzenesulfonic Acid | 2022 |
Anterior insular cortex mediates hyperalgesia induced by chronic pancreatitis in rats.
Topics: Abdomen; Animals; Anxiety; Behavior, Animal; Cell Membrane; Cerebral Cortex; Glutamic Acid; Hyperalgesia; Hypersensitivity; Long-Term Potentiation; Male; Neurotransmitter Agents; Pancreatitis, Chronic; Phosphorylation; Presynaptic Terminals; Protein Subunits; Proto-Oncogene Proteins c-fos; Pyramidal Cells; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Trinitrobenzenesulfonic Acid | 2019 |
Nucleus tractus solitarius mediates hyperalgesia induced by chronic pancreatitis in rats.
Topics: Afferent Pathways; Animals; Chronic Pain; Disease Models, Animal; Enteric Nervous System; Humans; Hyperalgesia; Male; Neurons; Pancreas; Pancreatitis, Chronic; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Solitary Nucleus; Stereotaxic Techniques; Synaptic Transmission; Trinitrobenzenesulfonic Acid | 2019 |
Neonatal immune challenge followed by adult immune challenge induces epigenetic-susceptibility to aggravated visceral hypersensitivity.
Topics: Abdominal Pain; Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Epigenesis, Genetic; Gene Expression Regulation; Hyperalgesia; Inflammation; Male; Rats; Rats, Sprague-Dawley; Spinal Cord; Trinitrobenzenesulfonic Acid; Visceral Pain | 2017 |
Inhibition of the high affinity choline transporter enhances hyperalgesia in a rat model of chronic pancreatitis.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Hemicholinium 3; Hyperalgesia; Injections, Intraperitoneal; Male; Nerve Tissue Proteins; Pancreatitis, Chronic; Plasma Membrane Neurotransmitter Transport Proteins; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Trinitrobenzenesulfonic Acid | 2017 |
Percutaneous electrical nerve field stimulation modulates central pain pathways and attenuates post-inflammatory visceral and somatic hyperalgesia in rats.
Topics: Animals; Disease Models, Animal; Hyperalgesia; Inflammation; Male; Neurons; Rats, Sprague-Dawley; Spinal Cord; Transcutaneous Electric Nerve Stimulation; Trinitrobenzenesulfonic Acid; Visceral Pain | 2017 |
Neuronal Transforming Growth Factor beta Signaling via SMAD3 Contributes to Pain in Animal Models of Chronic Pancreatitis.
Topics: Animals; Ceruletide; Disease Models, Animal; Fibrosis; Humans; Hyperalgesia; Male; Mice; Mice, Transgenic; Nociceptors; Pain; Pancreas; Pancreatitis, Chronic; Patch-Clamp Techniques; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Recombinant Proteins; Signal Transduction; Smad3 Protein; Synaptic Potentials; Transforming Growth Factor beta; Trinitrobenzenesulfonic Acid | 2018 |
MicroRNA-146a-5p attenuates visceral hypersensitivity through targeting chemokine CCL8 in the spinal cord in a mouse model of colitis.
Topics: Animals; Antagomirs; Antibodies; Cells, Cultured; Chemokine CCL8; Colitis; Disease Models, Animal; Gene Expression Regulation; Humans; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; MicroRNAs; Peroxidase; RNA, Small Interfering; Spinal Cord; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha; Up-Regulation; Visceral Pain | 2018 |
Chronic linaclotide treatment reduces colitis-induced neuroplasticity and reverses persistent bladder dysfunction.
Topics: Afferent Pathways; Animals; Colitis; Colon; Disease Models, Animal; Drug Administration Schedule; Guanylyl Cyclase C Agonists; Humans; Hyperalgesia; Irritable Bowel Syndrome; Male; Mice; Neuronal Plasticity; Nociception; Peptides; Treatment Outcome; Trinitrobenzenesulfonic Acid; Urinary Bladder; Urinary Bladder, Overactive | 2018 |
Electroacupuncture Alleviated Referral Hindpaw Hyperalgesia via Suppressing Spinal Long-Term Potentiation (LTP) in TNBS-Induced Colitis Rats.
Topics: Animals; Colitis; Disease Models, Animal; Electroacupuncture; Hindlimb; Hyperalgesia; Long-Term Potentiation; Male; Nociception; Pain Threshold; Rats, Sprague-Dawley; Spinal Cord; Trinitrobenzenesulfonic Acid | 2019 |
Gastrointestinal pain: unraveling a novel endogenous pathway through uroguanylin/guanylate cyclase-C/cGMP activation.
Topics: Acetylcholine; Acetylglucosamine; Adenocarcinoma; Animals; Cell Differentiation; Cell Line, Tumor; Colitis; Colon; Colorectal Neoplasms; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Female; Gastrointestinal Diseases; Gene Expression Regulation, Neoplastic; Guanylate Cyclase; Humans; Hyperalgesia; Intestinal Mucosa; Male; Mast Cells; Morphine; Multidrug Resistance-Associated Proteins; Natriuretic Peptides; Organic Anion Transporters, Sodium-Independent; Peroxidase; Rats; Rats, Sprague-Dawley; Rats, Wistar; Restraint, Physical; RNA, Messenger; Signal Transduction; Trinitrobenzenesulfonic Acid; Visceral Pain | 2013 |
Analgesic effect of minocycline in rat model of inflammation-induced visceral pain.
Topics: Analgesics; Animals; Behavior, Animal; Colitis; Colon; Disease Models, Animal; Ganglia, Spinal; Hyperalgesia; Injections, Intraperitoneal; Injections, Spinal; Male; Mechanotransduction, Cellular; Microglia; Minocycline; Pain Perception; Pressure; Rats, Sprague-Dawley; Spinal Cord; Time Factors; Trinitrobenzenesulfonic Acid; Visceral Pain | 2014 |
Neuron-glial communication mediated by TNF-α and glial activation in dorsal root ganglia in visceral inflammatory hypersensitivity.
Topics: Animals; Animals, Newborn; Antibodies, Monoclonal; Behavior, Animal; Cell Communication; Cell Surface Extensions; Cells, Cultured; Colitis; Colon; Disease Models, Animal; Electric Stimulation; Ganglia, Spinal; Gap Junctions; Hyperalgesia; Inflammation Mediators; Male; Neuroglia; Neurons; Pain Threshold; Pressure; Rats; Rats, Sprague-Dawley; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha; Up-Regulation | 2014 |
The effect of chemically induced colitis, psychological stress and their combination on visceral pain in female Wistar rats.
Topics: Animals; Colitis; Female; Hyperalgesia; Rats; Rats, Wistar; Stress, Psychological; Trinitrobenzenesulfonic Acid; Visceral Pain | 2014 |
Altered vasoactive intestinal peptides expression in irritable bowel syndrome patients and rats with trinitrobenzene sulfonic acid-induced colitis.
Topics: Adult; Animals; Biomarkers; Case-Control Studies; Colitis; Colon; Disease Models, Animal; Female; Gene Expression Regulation; Humans; Hyperalgesia; Inflammation Mediators; Irritable Bowel Syndrome; Male; Middle Aged; Pain Threshold; Peroxidase; Pilot Projects; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Time Factors; Trinitrobenzenesulfonic Acid; Vasoactive Intestinal Peptide; Visceral Pain; Weight Loss; Young Adult | 2015 |
Adrenergic signaling mediates mechanical hyperalgesia through activation of P2X3 receptors in primary sensory neurons of rats with chronic pancreatitis.
Topics: Adenosine Triphosphate; Adrenergic beta-2 Receptor Antagonists; Animals; Behavior, Animal; Calcium Signaling; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Ganglia, Spinal; Hyperalgesia; Male; Membrane Potentials; Motor Activity; Norepinephrine; Pain Threshold; Pancreas; Pancreatitis, Chronic; Protein Kinase Inhibitors; Purinergic P2X Receptor Antagonists; Rats, Sprague-Dawley; Receptor Cross-Talk; Receptors, Adrenergic, beta-2; Receptors, Purinergic P2X3; Sensory Receptor Cells; Time Factors; Trinitrobenzenesulfonic Acid | 2015 |
P2X3 receptors mediate visceral hypersensitivity during acute chemically-induced colitis and in the post-inflammatory phase via different mechanisms of sensitization.
Topics: Adenosine Triphosphate; Animals; Colitis; Colon; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperalgesia; Inflammation; Male; Phenols; Polycyclic Compounds; Purinergic P2X Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2X3; Trinitrobenzenesulfonic Acid | 2015 |
Involvement of peripheral artemin signaling in tongue pain: possible mechanism in burning mouth syndrome.
Topics: Aged; Aged, 80 and over; Anilides; Animals; Antibodies, Neutralizing; Blotting, Western; Burning Mouth Syndrome; Cinnamates; Disease Models, Animal; Female; Glial Cell Line-Derived Neurotrophic Factor Receptors; Glossalgia; Hot Temperature; Humans; Hyperalgesia; Male; Mice; Middle Aged; Nerve Tissue Proteins; Neurons; Patch-Clamp Techniques; Real-Time Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tongue; Trigeminal Ganglion; Trinitrobenzenesulfonic Acid; TRPV Cation Channels | 2015 |
Activation of colo-rectal high-threshold afferent nerves by Interleukin-2 is tetrodotoxin-sensitive and upregulated in a mouse model of chronic visceral hypersensitivity.
Topics: Adaptive Immunity; Afferent Pathways; Animals; Colitis; Disease Models, Animal; Ganglia, Spinal; Hyperalgesia; Interleukin-2; Irritable Bowel Syndrome; Mice; NAV1.7 Voltage-Gated Sodium Channel; Neurons, Afferent; Peroxidase; Real-Time Polymerase Chain Reaction; Receptors, Interleukin-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium Channel Blockers; Tetrodotoxin; Trinitrobenzenesulfonic Acid; Visceral Pain | 2016 |
Elevated H2 O2 levels in trinitrobenzene sulfate-induced colitis rats contributes to visceral hyperalgesia through interaction with the transient receptor potential ankyrin 1 cation channel.
Topics: Abdominal Pain; Acetanilides; Acetylcysteine; Administration, Intravenous; Animals; Colitis; Colon; Disease Models, Animal; Free Radical Scavengers; Hydrogen Peroxide; Hyperalgesia; Male; Pain Threshold; Purines; Rats, Sprague-Dawley; Signal Transduction; Time Factors; Trinitrobenzenesulfonic Acid; TRPV Cation Channels; Up-Regulation; Visceral Pain | 2016 |
Gender-related differential effect of tachykinin NK2 receptor-mediated visceral hyperalgesia in guinea pig colon.
Topics: Animals; Colitis; Colon; Dipeptides; Disease Models, Animal; Female; Guinea Pigs; Hyperalgesia; Male; Receptors, Neurokinin-2; Sex Characteristics; Thiophenes; Trinitrobenzenesulfonic Acid; Visceral Pain | 2016 |
Transient receptor potential ankyrin-1 participates in visceral hyperalgesia following experimental colitis.
Topics: Animals; Ankyrins; Calcium Channels; Colitis; Colon; Disease Models, Animal; Electromyography; Gastrointestinal Motility; Hyperalgesia; Male; Oligodeoxyribonucleotides, Antisense; Pain Measurement; Pain Threshold; Rats; Rats, Wistar; Stimulation, Chemical; Trinitrobenzenesulfonic Acid; TRPA1 Cation Channel; TRPC Cation Channels; TRPV Cation Channels; Up-Regulation; Visceral Afferents | 2008 |
Inhibition of endothelial cell adhesion molecule expression improves colonic hyperalgaesia.
Topics: Animals; Cell Adhesion; Cell Adhesion Molecules; Colitis; Colon; Dilatation, Pathologic; E-Selectin; Endothelial Cells; Gastrointestinal Motility; Humans; Hyperalgesia; Intercellular Adhesion Molecule-1; Leukocytes; Male; Polyethylene Glycols; Purines; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; Restraint, Physical; Stress, Psychological; Trinitrobenzenesulfonic Acid; Zymosan | 2009 |
Peripheral anti-nociceptive effect of nociceptin/orphanin FQ in inflammation and stress-induced colonic hyperalgesia in rats.
Topics: Analgesics; Animals; Colitis; Colon; Disease Models, Animal; Drug Administration Routes; Drug Interactions; Electromyography; Gene Expression Regulation; Hyperalgesia; Nociceptin; Nociceptin Receptor; Opioid Peptides; Peroxidase; Physical Stimulation; Rats; Rats, Wistar; Receptors, Opioid; Restraint, Physical; Sensory Thresholds; Stress, Psychological; Trinitrobenzenesulfonic Acid | 2009 |
The ion channel TRPA1 is required for normal mechanosensation and is modulated by algesic stimuli.
Topics: Action Potentials; Afferent Pathways; Animals; Bradykinin; Capsaicin; Colitis; Colon; Disease Models, Animal; Female; Ganglia, Spinal; Hyperalgesia; Immunohistochemistry; In Situ Hybridization; Intestinal Mucosa; Male; Mechanotransduction, Cellular; Mice; Mice, Inbred C57BL; Mice, Knockout; Neuroanatomical Tract-Tracing Techniques; Nodose Ganglion; Pain Measurement; Pelvis; Pressure; Receptor, PAR-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Splanchnic Nerves; Stimulation, Chemical; Transient Receptor Potential Channels; Trinitrobenzenesulfonic Acid; TRPA1 Cation Channel | 2009 |
Guanylate cyclase C-mediated antinociceptive effects of linaclotide in rodent models of visceral pain.
Topics: Abdomen; Analysis of Variance; Animals; Colon; Electrodes, Implanted; Electromyography; Female; Guanylate Cyclase; Hyperalgesia; Inflammation; Male; Mice; Mice, Knockout; Muscle Contraction; Muscle, Smooth; Pain; Peptides; Rats; Rats, Wistar; Restraint, Physical; Statistics, Nonparametric; Stress, Physiological; Stress, Psychological; Trinitrobenzenesulfonic Acid | 2010 |
The role of brain-derived neurotrophic factor in experimental inflammation of mouse gut.
Topics: Analysis of Variance; Animals; Brain-Derived Neurotrophic Factor; Colitis; Colon; Enzyme-Linked Immunosorbent Assay; Ganglia, Spinal; Hyperalgesia; Inflammation; Male; Mice; Mice, Knockout; Physical Stimulation; Random Allocation; Trinitrobenzenesulfonic Acid; Up-Regulation; Urinary Bladder | 2010 |
Endothelins implicated in referred mechanical hyperalgesia associated with colitis induced by TNBS in mice.
Topics: Abdominal Pain; Animals; Atrasentan; Colitis; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelins; Foot; Hindlimb; Hyperalgesia; Male; Mice; Mice, Inbred BALB C; Morphine; Pain, Referred; Pyrrolidines; Touch; Trinitrobenzenesulfonic Acid | 2010 |
Modulation of visceral hypersensitivity by glial cell line-derived neurotrophic factor family receptor α-3 in colorectal afferents.
Topics: Animals; Colitis; Colon; Disease Models, Animal; Electromyography; Evoked Potentials; Ganglia, Spinal; Glial Cell Line-Derived Neurotrophic Factor Receptors; Hyperalgesia; Mechanotransduction, Cellular; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Tissue Proteins; Neurons, Afferent; Pressure; Rectum; Time Factors; Trinitrobenzenesulfonic Acid | 2011 |
Proteinase-activated receptor 2 mediates thermal hyperalgesia and is upregulated in a rat model of chronic pancreatitis.
Topics: Abdominal Pain; Analgesics; Animals; Behavior, Animal; Blotting, Western; Disease Models, Animal; Dose-Response Relationship, Drug; Fluorescent Antibody Technique; Ganglia, Spinal; Glycoproteins; Hyperalgesia; Male; Pain Measurement; Pain Threshold; Pancreatitis, Chronic; Rats; Rats, Sprague-Dawley; Reaction Time; Receptor, PAR-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Trinitrobenzenesulfonic Acid; TRPV Cation Channels; Up-Regulation | 2011 |
Nerve growth factor modulates TRPV1 expression and function and mediates pain in chronic pancreatitis.
Topics: Analgesics; Analysis of Variance; Animals; Antibodies; Disease Models, Animal; Down-Regulation; Hyperalgesia; Male; Membrane Potentials; Nerve Growth Factor; Pain; Pain Threshold; Pancreas; Pancreatitis, Chronic; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sensory Receptor Cells; Signal Transduction; Time Factors; Trinitrobenzenesulfonic Acid; TRPV Cation Channels | 2011 |
Spinal microglia initiate and maintain hyperalgesia in a rat model of chronic pancreatitis.
Topics: Animals; Blotting, Western; CD11 Antigens; Chemokine CX3CL1; Disease Models, Animal; Enzyme Activation; Hyperalgesia; Immunohistochemistry; Male; Microglia; Minocycline; p38 Mitogen-Activated Protein Kinases; Pain Measurement; Pain Threshold; Pancreatitis, Chronic; Phosphorylation; Rats; Rats, Sprague-Dawley; Spinal Cord; Thoracic Vertebrae; Time Factors; Trinitrobenzenesulfonic Acid | 2012 |
Proteinase-activated receptor-4 evoked colorectal analgesia in mice: an endogenously activated feed-back loop in visceral inflammatory pain.
Topics: Animals; Colon; Dilatation, Pathologic; Electromyography; Feedback, Physiological; Hyperalgesia; Inflammation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, SCID; Oligopeptides; Proto-Oncogene Proteins c-fos; Receptors, Thrombin; Rectum; Trinitrobenzenesulfonic Acid; Visceral Pain | 2012 |
Resolvin D1 reverses chronic pancreatitis-induced mechanical allodynia, phosphorylation of NMDA receptors, and cytokines expression in the thoracic spinal dorsal horn.
Topics: Abdominal Pain; Animals; Anti-Inflammatory Agents; Anxiety; Docosahexaenoic Acids; Exploratory Behavior; Hyperalgesia; Injections, Spinal; Interleukin-1beta; Interleukin-6; Locomotion; Male; Pancreatitis, Chronic; Phosphorylation; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha | 2012 |
A low dose of fermented soy germ alleviates gut barrier injury, hyperalgesia and faecal protease activity in a rat model of inflammatory bowel disease.
Topics: Animals; Cytokines; Disease Models, Animal; Enzyme Activation; Feces; Female; Glycine max; Humans; Hyperalgesia; Inflammatory Bowel Diseases; Intestinal Mucosa; Peptide Hydrolases; Permeability; Plant Extracts; Rats; Receptor, PAR-2; Trinitrobenzenesulfonic Acid; Weight Loss | 2012 |
Host immune response determines visceral hyperalgesia in a rat model of post-inflammatory irritable bowel syndrome.
Topics: Animals; Colitis; Colon; Disease Models, Animal; Hyperalgesia; Interleukin-2; Interleukin-6; Irritable Bowel Syndrome; Male; Rats; Rats, Inbred F344; Rats, Inbred Lew; Trinitrobenzenesulfonic Acid | 2013 |
Decrease in non-selective, non-sustained attention induced by a chronic visceral inflammatory state as a new pain evaluation in rats.
Topics: Acetaminophen; Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Attention; Behavior, Animal; Chronic Disease; Cognition Disorders; Colitis; Dose-Response Relationship, Drug; Hyperalgesia; Ibuprofen; Inflammation; Male; Morphine; Pain; Pain Measurement; Physical Stimulation; Rats; Rats, Sprague-Dawley; Trinitrobenzenesulfonic Acid; Visceral Afferents | 2004 |
A combination of peppermint oil and caraway oil attenuates the post-inflammatory visceral hyperalgesia in a rat model.
Topics: Administration, Rectal; Animals; Colon; Disease Models, Animal; Drug Therapy, Combination; Ethanol; Hyperalgesia; Male; Mentha piperita; Nociceptors; Oils, Volatile; Parasympatholytics; Plant Oils; Rats; Rats, Inbred Lew; Treatment Outcome; Trinitrobenzenesulfonic Acid; Viscera | 2006 |
Psychological stress and the severity of post-inflammatory visceral hyperalgesia.
Topics: Abdominal Muscles; Acute Disease; Animals; Avoidance Learning; Behavior, Animal; Colon; Dilatation; Disease Models, Animal; Drinking Behavior; Electromyography; Ethanol; Female; Hyperalgesia; Inflammation; Interleukin-2; Pain Threshold; Rats; Rats, Inbred Lew; Rectum; Severity of Illness Index; Solvents; Stress, Psychological; Trinitrobenzenesulfonic Acid; Viscera; Visceral Afferents | 2007 |
Severity of mucosal inflammation as a predictor for alterations of visceral sensory function in a rat model.
Topics: Abdominal Muscles; Acute Disease; Animals; Catheterization; Colitis; Colon; Dilatation, Pathologic; Disease Models, Animal; Electromyography; Enzyme-Linked Immunosorbent Assay; Hyperalgesia; Interleukin-2; Interleukin-6; Intestinal Mucosa; Irritable Bowel Syndrome; Male; Rats; Rats, Inbred Lew; Rectum; Sensation Disorders; Severity of Illness Index; Time Factors; Trinitrobenzenesulfonic Acid | 2006 |
Visceral and somatic hypersensitivity in a subset of rats following TNBS-induced colitis.
Topics: Animals; Colitis; Hot Temperature; Hyperalgesia; Male; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Somatosensory Disorders; Touch; Trinitrobenzenesulfonic Acid; Visceral Afferents | 2008 |
Transient receptor potential vanilloid 1 mediates hyperalgesia and is up-regulated in rats with chronic pancreatitis.
Topics: Anilides; Animals; Behavior, Animal; Capsaicin; Cinnamates; Disease Models, Animal; Electric Stimulation; Ganglia, Spinal; Hyperalgesia; Male; Membrane Potentials; Pain Measurement; Pain Threshold; Pancreas; Pancreatitis, Chronic; Rats; Rats, Sprague-Dawley; RNA, Messenger; Time Factors; Trinitrobenzenesulfonic Acid; TRPV Cation Channels; Up-Regulation | 2007 |
Visceral and somatic hypersensitivity in TNBS-induced colitis in rats.
Topics: Animals; Colitis; Disease Models, Animal; Hyperalgesia; Male; Rats; Rats, Sprague-Dawley; Touch; Trinitrobenzenesulfonic Acid; Viscera; Visceral Afferents | 2008 |
The role of transient receptor potential vanilloid 1 in mechanical and chemical visceral hyperalgesia following experimental colitis.
Topics: Animals; Capsaicin; Colitis; Disease Models, Animal; Drug Administration Schedule; Drug Interactions; Electromyography; Ganglia, Spinal; Gastrointestinal Motility; Hyperalgesia; Male; Neurons; Rats; Rats, Sprague-Dawley; Reflex, Abdominal; Sulfonamides; Thiourea; Time Factors; Trinitrobenzenesulfonic Acid; TRPV Cation Channels; Visceral Afferents | 2007 |
Effect of a new alpha 2 delta ligand PD-217014 on visceral hypersensitivity induced by 2,4,6-trinitrobenzene sulfonic acid in rats.
Topics: Analgesics; Animals; Binding Sites; Bridged Bicyclo Compounds; Calcium Channels; Calcium Channels, L-Type; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Hyperalgesia; Ligands; Male; Pain Measurement; Rats; Rats, Sprague-Dawley; Swine; Trinitrobenzenesulfonic Acid; Viscera | 2008 |
Hind paw incision in the rat produces long-lasting colon hypersensitivity.
Topics: Animals; Colitis; Disease Models, Animal; Hindlimb; Hyperalgesia; Male; Pain Measurement; Pain Threshold; Physical Stimulation; Rats; Rats, Sprague-Dawley; Reaction Time; Time Factors; Trinitrobenzenesulfonic Acid; Viscera | 2008 |
Abolishment of TNBS-induced visceral hypersensitivity in mast cell deficient rats.
Topics: Animals; Colon; Disease Models, Animal; Hyperalgesia; Inflammatory Bowel Diseases; Intestinal Mucosa; Male; Mast Cells; Necrosis; Pain Threshold; Peroxidase; Rats; Trinitrobenzenesulfonic Acid | 2008 |
Influence of trimebutine on inflammation- and stress-induced hyperalgesia to rectal distension in rats.
Topics: Animals; Anti-Inflammatory Agents; Colitis; Gastrointestinal Agents; Hyperalgesia; Male; Peritoneal Cavity; Proctitis; Rats; Rats, Wistar; Receptors, Opioid; Rectum; Restraint, Physical; Trimebutine; Trinitrobenzenesulfonic Acid | 1998 |
Role of tachykinin NK2 receptors in normal and altered rectal sensitivity in rats.
Topics: Animals; Colon; Compliance; Electromyography; Female; Hyperalgesia; In Vitro Techniques; Inflammation; Male; Peptides, Cyclic; Rats; Rats, Wistar; Receptors, Neurokinin-2; Rectum; Stress, Psychological; Trinitrobenzenesulfonic Acid | 2000 |