trimipramine has been researched along with Neuroleptic Malignant Syndrome in 2 studies
Trimipramine: Tricyclic antidepressant similar to IMIPRAMINE, but with more antihistaminic and sedative properties.
trimipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)-2-methylpropyl group at the nitrogen atom. It is used as an antidepressant.
Neuroleptic Malignant Syndrome: A potentially fatal syndrome associated primarily with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS) which are in turn associated with dopaminergic receptor blockade (see RECEPTORS, DOPAMINE) in the BASAL GANGLIA and HYPOTHALAMUS, and sympathetic dysregulation. Clinical features include diffuse MUSCLE RIGIDITY; TREMOR; high FEVER; diaphoresis; labile blood pressure; cognitive dysfunction; and autonomic disturbances. Serum CPK level elevation and a leukocytosis may also be present. (From Adams et al., Principles of Neurology, 6th ed, p1199; Psychiatr Serv 1998 Sep;49(9):1163-72)
| Excerpt | Relevance | Reference |
|---|---|---|
| "A case of neuroleptic malignant syndrome (NMS) was induced by the antidepressant trimipramine in a 47-year-old woman with obsessive compulsive disorder and major depression." | 7.67 | Trimipramine-induced neuroleptic malignant syndrome after transient psychogenic polydipsia in one patient. ( Alarcon, RD; Langlow, JR, 1989) |
| "A case of neuroleptic malignant syndrome (NMS) was induced by the antidepressant trimipramine in a 47-year-old woman with obsessive compulsive disorder and major depression." | 3.67 | Trimipramine-induced neuroleptic malignant syndrome after transient psychogenic polydipsia in one patient. ( Alarcon, RD; Langlow, JR, 1989) |
| " We discuss a possible relation between serotonin syndrome and a highly dosed combination therapy with moclobemide." | 1.29 | [Depressive stupor--malignant neuroleptic syndrome--serotonin syndrome. A case contribution to a difficult differential diagnosis]. ( König, F; Löble, M; Wolfersdorf, M, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| König, F | 1 |
| Löble, M | 1 |
| Wolfersdorf, M | 1 |
| Langlow, JR | 1 |
| Alarcon, RD | 1 |
2 other studies available for trimipramine and Neuroleptic Malignant Syndrome
| Article | Year |
|---|---|
[Depressive stupor--malignant neuroleptic syndrome--serotonin syndrome. A case contribution to a difficult differential diagnosis].
Topics: Antidepressive Agents, Tricyclic; Antipsychotic Agents; Benzamides; Depressive Disorder; Diagnosis, | 1996 |
Trimipramine-induced neuroleptic malignant syndrome after transient psychogenic polydipsia in one patient.
Topics: Depressive Disorder; Dibenzazepines; Drinking Behavior; Female; Humans; Middle Aged; Neuroleptic Mal | 1989 |