trimetrexate has been researched along with Recrudescence in 4 studies
Trimetrexate: A nonclassical folic acid inhibitor through its inhibition of the enzyme dihydrofolate reductase. It is being tested for efficacy as an antineoplastic agent and as an antiparasitic agent against PNEUMOCYSTIS PNEUMONIA in AIDS patients. Myelosuppression is its dose-limiting toxic effect.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pappo, A | 1 |
| Dubowy, R | 1 |
| Ravindranath, Y | 1 |
| Alvarado, C | 1 |
| Rao, S | 1 |
| Whitehead, VM | 1 |
| Vega, R | 1 |
| Kamen, B | 1 |
| Vietti, T | 1 |
| Faber, HJ | 1 |
| Sprenger, HG | 1 |
| Weits, J | 1 |
| Kovacs, JA | 1 |
| Masur, H | 1 |
1 review available for trimetrexate and Recrudescence
| Article | Year |
|---|---|
Pneumocystis carinii pneumonia: therapy and prophylaxis.
Topics: Acquired Immunodeficiency Syndrome; Anti-Bacterial Agents; Dapsone; Drug Combinations; Drug Therapy, | 1988 |
1 trial available for trimetrexate and Recrudescence
| Article | Year |
|---|---|
Phase II trial of trimetrexate in the treatment of recurrent childhood acute lymphoblastic leukemia: a Pediatric Oncology Group study.
Topics: Adolescent; Child; Child, Preschool; Drug Administration Schedule; Female; Humans; Infant; Infusions | 1990 |
2 other studies available for trimetrexate and Recrudescence
| Article | Year |
|---|---|
Relapse Pneumocystis carinii pneumonitis and adverse reaction to current therapy in patients with AIDS: trimetrexate as an alternative.
Topics: Acquired Immunodeficiency Syndrome; Adult; Folic Acid Antagonists; Humans; Male; Pneumonia, Pneumocy | 1990 |
Treatment of Pneumocystis carinii pneumonia.
Topics: Acquired Immunodeficiency Syndrome; Dapsone; Drug Combinations; Folic Acid Antagonists; Humans; Meth | 1987 |