Page last updated: 2024-11-05

trimetrexate and Malaria

trimetrexate has been researched along with Malaria in 1 studies

Trimetrexate: A nonclassical folic acid inhibitor through its inhibition of the enzyme dihydrofolate reductase. It is being tested for efficacy as an antineoplastic agent and as an antiparasitic agent against PNEUMOCYSTIS PNEUMONIA in AIDS patients. Myelosuppression is its dose-limiting toxic effect.

Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nzila, A1
Okombo, J1
Becker, RP1
Chilengi, R1
Lang, T1
Niehues, T1

Other Studies

1 other study available for trimetrexate and Malaria

ArticleYear
Anticancer agents against malaria: time to revisit?
    Trends in parasitology, 2010, Volume: 26, Issue:3

    Topics: Antimalarials; Antineoplastic Agents; Humans; Malaria; Methotrexate; Trimetrexate

2010