trimetrexate has been researched along with Candidiasis in 1 studies
Trimetrexate: A nonclassical folic acid inhibitor through its inhibition of the enzyme dihydrofolate reductase. It is being tested for efficacy as an antineoplastic agent and as an antiparasitic agent against PNEUMOCYSTIS PNEUMONIA in AIDS patients. Myelosuppression is its dose-limiting toxic effect.
Candidiasis: Infection with a fungus of the genus CANDIDA. It is usually a superficial infection of the moist areas of the body and is generally caused by CANDIDA ALBICANS. (Dorland, 27th ed)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kuyper, LF | 1 |
| Baccanari, DP | 1 |
| Jones, ML | 1 |
| Hunter, RN | 1 |
| Tansik, RL | 1 |
| Joyner, SS | 1 |
| Boytos, CM | 1 |
| Rudolph, SK | 1 |
| Knick, V | 1 |
| Wilson, HR | 1 |
| Caddell, JM | 1 |
| Friedman, HS | 1 |
| Comley, JC | 1 |
| Stables, JN | 1 |
1 other study available for trimetrexate and Candidiasis
| Article | Year |
|---|---|
High-affinity inhibitors of dihydrofolate reductase: antimicrobial and anticancer activities of 7,8-dialkyl-1,3-diaminopyrrolo[3,2-f]quinazolines with small molecular size.
Topics: Animals; Anti-Infective Agents; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B | 1996 |