trimetrexate has been researched along with Candida Infection in 1 studies
Trimetrexate: A nonclassical folic acid inhibitor through its inhibition of the enzyme dihydrofolate reductase. It is being tested for efficacy as an antineoplastic agent and as an antiparasitic agent against PNEUMOCYSTIS PNEUMONIA in AIDS patients. Myelosuppression is its dose-limiting toxic effect.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kuyper, LF | 1 |
| Baccanari, DP | 1 |
| Jones, ML | 1 |
| Hunter, RN | 1 |
| Tansik, RL | 1 |
| Joyner, SS | 1 |
| Boytos, CM | 1 |
| Rudolph, SK | 1 |
| Knick, V | 1 |
| Wilson, HR | 1 |
| Caddell, JM | 1 |
| Friedman, HS | 1 |
| Comley, JC | 1 |
| Stables, JN | 1 |
1 other study available for trimetrexate and Candida Infection
| Article | Year |
|---|---|
High-affinity inhibitors of dihydrofolate reductase: antimicrobial and anticancer activities of 7,8-dialkyl-1,3-diaminopyrrolo[3,2-f]quinazolines with small molecular size.
Topics: Animals; Anti-Infective Agents; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B | 1996 |