trimethyloxamine has been researched along with Vascular Diseases in 10 studies
trimethyloxamine: used in manufacture of quaternary ammonium cpds; insect attractant; warming agent for gas; oxidant; structure
trimethylamine N-oxide : A tertiary amine oxide resulting from the oxidation of the amino group of trimethylamine.
Vascular Diseases: Pathological processes involving any of the BLOOD VESSELS in the cardiac or peripheral circulation. They include diseases of ARTERIES; VEINS; and rest of the vasculature system in the body.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Endothelial dysfunction is a critical initiating factor contributing to cardiovascular diseases, involving the gut microbiome-derived metabolite trimethylamine N-oxide (TMAO)." | 8.31 | Time-dependent specific molecular signatures of inflammation and remodelling are associated with trimethylamine-N-oxide (TMAO)-induced endothelial cell dysfunction. ( Bellanger, S; Cheong, KH; Chin, YL; Devasia, AG; Leo, CH; Ong, ES; Ramasamy, A; Shanmugham, M, 2023) |
| "Endothelial dysfunction is a critical initiating factor contributing to cardiovascular diseases, involving the gut microbiome-derived metabolite trimethylamine N-oxide (TMAO)." | 4.31 | Time-dependent specific molecular signatures of inflammation and remodelling are associated with trimethylamine-N-oxide (TMAO)-induced endothelial cell dysfunction. ( Bellanger, S; Cheong, KH; Chin, YL; Devasia, AG; Leo, CH; Ong, ES; Ramasamy, A; Shanmugham, M, 2023) |
| "Dysbiosis is associated with intestinal inflammation and reduced integrity of the gut barrier, which in turn increases circulating levels of bacterial structural components and microbial metabolites that may facilitate the development of CVD." | 2.58 | The gut microbiota as a novel regulator of cardiovascular function and disease. ( Battson, ML; Gentile, CL; Lee, DM; Weir, TL, 2018) |
| "Vascular dysfunction: develops progressively with ageing; increases the risk of cardiovascular diseases (CVD); and is characterized by endothelial dysfunction and arterial stiffening, which are primarily mediated by superoxide-driven oxidative stress and consequently reduced nitric oxide (NO) bioavailability and arterial structural changes." | 1.72 | Initiation of 3,3-dimethyl-1-butanol at midlife prevents endothelial dysfunction and attenuates in vivo aortic stiffening with ageing in mice. ( Brunt, VE; Casso, AG; Clayton, ZS; Davy, KP; Gioscia-Ryan, RA; Greenberg, NT; Hutton, DA; Neilson, AP; Seals, DR; VanDongen, NS; Ziemba, BP, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 6 (60.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jomard, A | 1 |
| Liberale, L | 1 |
| Doytcheva, P | 1 |
| Reiner, MF | 1 |
| Müller, D | 1 |
| Visentin, M | 1 |
| Bueter, M | 1 |
| Lüscher, TF | 1 |
| Vettor, R | 1 |
| Lutz, TA | 1 |
| Camici, GG | 1 |
| Osto, E | 1 |
| Casso, AG | 1 |
| VanDongen, NS | 1 |
| Gioscia-Ryan, RA | 1 |
| Clayton, ZS | 1 |
| Greenberg, NT | 1 |
| Ziemba, BP | 1 |
| Hutton, DA | 1 |
| Neilson, AP | 1 |
| Davy, KP | 1 |
| Seals, DR | 1 |
| Brunt, VE | 1 |
| Deng, Y | 3 |
| Zou, J | 3 |
| Hong, Y | 3 |
| Peng, Q | 3 |
| Fu, X | 3 |
| Duan, R | 3 |
| Chen, J | 3 |
| Chen, X | 3 |
| Querio, G | 1 |
| Antoniotti, S | 1 |
| Geddo, F | 1 |
| Levi, R | 1 |
| Gallo, MP | 1 |
| Shanmugham, M | 1 |
| Devasia, AG | 1 |
| Chin, YL | 1 |
| Cheong, KH | 1 |
| Ong, ES | 1 |
| Bellanger, S | 1 |
| Ramasamy, A | 1 |
| Leo, CH | 1 |
| Matsumoto, T | 1 |
| Kojima, M | 1 |
| Takayanagi, K | 1 |
| Taguchi, K | 1 |
| Kobayashi, T | 1 |
| Li, T | 1 |
| Gua, C | 1 |
| Wu, B | 1 |
| Chen, Y | 1 |
| Battson, ML | 1 |
| Lee, DM | 1 |
| Weir, TL | 1 |
| Gentile, CL | 1 |
| Yang, G | 1 |
| Lin, CC | 1 |
| Yang, Y | 1 |
| Yuan, L | 2 |
| Wang, P | 1 |
| Wen, X | 1 |
| Pan, MH | 1 |
| Zhao, H | 1 |
| Ho, CT | 1 |
| Li, S | 1 |
| Hu, Y | 1 |
| Zhao, Y | 1 |
| Yang, X | 1 |
3 reviews available for trimethyloxamine and Vascular Diseases
| Article | Year |
|---|---|
Modulation of Endothelial Function by TMAO, a Gut Microbiota-Derived Metabolite.
Topics: Gastrointestinal Microbiome; Humans; Methylamines; Vascular Diseases | 2023 |
Role of S-Equol, Indoxyl Sulfate, and Trimethylamine N-Oxide on Vascular Function.
Topics: Animals; Endothelial Cells; Endothelium, Vascular; Equol; Gastrointestinal Microbiome; Humans; Indic | 2020 |
The gut microbiota as a novel regulator of cardiovascular function and disease.
Topics: Aging; Animals; Anti-Bacterial Agents; Atherosclerosis; Bile Acids and Salts; Cardiovascular Disease | 2018 |
7 other studies available for trimethyloxamine and Vascular Diseases
| Article | Year |
|---|---|
Effects of acute administration of trimethylamine N-oxide on endothelial function: a translational study.
Topics: Animals; Endothelial Cells; Endothelium, Vascular; Humans; Methylamines; Mice; Rats; Vascular Diseas | 2022 |
Initiation of 3,3-dimethyl-1-butanol at midlife prevents endothelial dysfunction and attenuates in vivo aortic stiffening with ageing in mice.
Topics: Aging; Animals; Butanols; Cardiovascular Diseases; Drinking Water; Endothelium, Vascular; Humans; Mi | 2022 |
Higher Circulating Trimethylamine N-Oxide Aggravates Cognitive Impairment Probably via Downregulating Hippocampal SIRT1 in Vascular Dementia Rats.
Topics: Animals; Cognitive Dysfunction; Dementia, Vascular; Hippocampus; Inflammation; Rats; Sirtuin 1; Vasc | 2022 |
Higher Circulating Trimethylamine N-Oxide Aggravates Cognitive Impairment Probably via Downregulating Hippocampal SIRT1 in Vascular Dementia Rats.
Topics: Animals; Cognitive Dysfunction; Dementia, Vascular; Hippocampus; Inflammation; Rats; Sirtuin 1; Vasc | 2022 |
Higher Circulating Trimethylamine N-Oxide Aggravates Cognitive Impairment Probably via Downregulating Hippocampal SIRT1 in Vascular Dementia Rats.
Topics: Animals; Cognitive Dysfunction; Dementia, Vascular; Hippocampus; Inflammation; Rats; Sirtuin 1; Vasc | 2022 |
Higher Circulating Trimethylamine N-Oxide Aggravates Cognitive Impairment Probably via Downregulating Hippocampal SIRT1 in Vascular Dementia Rats.
Topics: Animals; Cognitive Dysfunction; Dementia, Vascular; Hippocampus; Inflammation; Rats; Sirtuin 1; Vasc | 2022 |
Higher Circulating Trimethylamine N-Oxide Aggravates Cognitive Impairment Probably via Downregulating Hippocampal SIRT1 in Vascular Dementia Rats.
Topics: Animals; Cognitive Dysfunction; Dementia, Vascular; Hippocampus; Inflammation; Rats; Sirtuin 1; Vasc | 2022 |
Higher Circulating Trimethylamine N-Oxide Aggravates Cognitive Impairment Probably via Downregulating Hippocampal SIRT1 in Vascular Dementia Rats.
Topics: Animals; Cognitive Dysfunction; Dementia, Vascular; Hippocampus; Inflammation; Rats; Sirtuin 1; Vasc | 2022 |
Higher Circulating Trimethylamine N-Oxide Aggravates Cognitive Impairment Probably via Downregulating Hippocampal SIRT1 in Vascular Dementia Rats.
Topics: Animals; Cognitive Dysfunction; Dementia, Vascular; Hippocampus; Inflammation; Rats; Sirtuin 1; Vasc | 2022 |
Higher Circulating Trimethylamine N-Oxide Aggravates Cognitive Impairment Probably via Downregulating Hippocampal SIRT1 in Vascular Dementia Rats.
Topics: Animals; Cognitive Dysfunction; Dementia, Vascular; Hippocampus; Inflammation; Rats; Sirtuin 1; Vasc | 2022 |
Higher Circulating Trimethylamine N-Oxide Aggravates Cognitive Impairment Probably via Downregulating Hippocampal SIRT1 in Vascular Dementia Rats.
Topics: Animals; Cognitive Dysfunction; Dementia, Vascular; Hippocampus; Inflammation; Rats; Sirtuin 1; Vasc | 2022 |
Time-dependent specific molecular signatures of inflammation and remodelling are associated with trimethylamine-N-oxide (TMAO)-induced endothelial cell dysfunction.
Topics: Endothelial Cells; Humans; Inflammation; Methylamines; Oxides; Vascular Diseases | 2023 |
Increased circulating trimethylamine N-oxide contributes to endothelial dysfunction in a rat model of chronic kidney disease.
Topics: Animals; Biomarkers; Cytokines; Endothelium, Vascular; Male; Methylamines; Rats; Rats, Sprague-Dawle | 2018 |
Nobiletin Prevents Trimethylamine Oxide-Induced Vascular Inflammation via Inhibition of the NF-κB/MAPK Pathways.
Topics: Animals; Aorta; Female; Flavones; Human Umbilical Vein Endothelial Cells; Humans; Liver; Male; Methy | 2019 |
Protective effects of tartary buckwheat flavonoids on high TMAO diet-induced vascular dysfunction and liver injury in mice.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Chemical and Drug Induced | 2015 |