trimethyloxamine has been researched along with Overweight in 7 studies
trimethyloxamine: used in manufacture of quaternary ammonium cpds; insect attractant; warming agent for gas; oxidant; structure
trimethylamine N-oxide : A tertiary amine oxide resulting from the oxidation of the amino group of trimethylamine.
Overweight: A status with BODY WEIGHT that is above certain standards. In the scale of BODY MASS INDEX, overweight is defined as having a BMI of 25.0-29.9 kg/m2. Overweight may or may not be due to increases in body fat (ADIPOSE TISSUE), hence overweight does not equal over fat.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our findings underscore the importance of changes in TMAO, choline and L-carnitine in improving insulin sensitivity during a weight-loss intervention for obese patients." | 5.30 | Gut microbiota metabolites, amino acid metabolites and improvements in insulin sensitivity and glucose metabolism: the POUNDS Lost trial. ( Bray, GA; DiDonato, JA; Heianza, Y; Li, X; Qi, L; Sacks, FM; Sun, D, 2019) |
| " We examined associations of weight loss diet-induced changes in a gut microbiota-related metabolite trimethylamine N-oxide (TMAO), and its precursors (choline and l-carnitine), with changes in bone mineral density (BMD) considering diabetes-related factors." | 5.30 | Circulating Gut Microbiota Metabolite Trimethylamine N-Oxide (TMAO) and Changes in Bone Density in Response to Weight Loss Diets: The POUNDS Lost Trial. ( Bray, GA; Chen, Y; DiDonato, JA; Heianza, Y; LeBoff, MS; Li, X; Pei, X; Qi, L; Sacks, FM; Sun, D; Zhou, T, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 4 (57.14) | 2.80 |
| Authors | Studies |
|---|---|
| Krishnan, S | 1 |
| Gertz, ER | 1 |
| Adams, SH | 1 |
| Newman, JW | 1 |
| Pedersen, TL | 1 |
| Keim, NL | 1 |
| Bennett, BJ | 1 |
| Rehman, A | 1 |
| Tyree, SM | 1 |
| Fehlbaum, S | 1 |
| DunnGalvin, G | 1 |
| Panagos, CG | 1 |
| Guy, B | 1 |
| Patel, S | 1 |
| Dinan, TG | 1 |
| Duttaroy, AK | 1 |
| Duss, R | 1 |
| Steinert, RE | 1 |
| Hagen, IV | 1 |
| Helland, A | 1 |
| Bratlie, M | 1 |
| Midttun, Ø | 1 |
| McCann, A | 1 |
| Sveier, H | 1 |
| Rosenlund, G | 1 |
| Mellgren, G | 1 |
| Ueland, PM | 1 |
| Gudbrandsen, OA | 1 |
| Zhu, C | 1 |
| Sawrey-Kubicek, L | 1 |
| Bardagjy, AS | 1 |
| Houts, H | 1 |
| Tang, X | 1 |
| Sacchi, R | 1 |
| Randolph, JM | 1 |
| Steinberg, FM | 1 |
| Zivkovic, AM | 1 |
| Heianza, Y | 2 |
| Sun, D | 2 |
| Li, X | 3 |
| DiDonato, JA | 2 |
| Bray, GA | 2 |
| Sacks, FM | 2 |
| Qi, L | 2 |
| Zhou, T | 1 |
| Chen, Y | 1 |
| Pei, X | 1 |
| LeBoff, MS | 1 |
| Bergeron, N | 1 |
| Williams, PT | 1 |
| Lamendella, R | 1 |
| Faghihnia, N | 1 |
| Grube, A | 1 |
| Wang, Z | 1 |
| Knight, R | 1 |
| Jansson, JK | 1 |
| Hazen, SL | 1 |
| Krauss, RM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Individual Metabolism and Physiology Signature Study[NCT02298725] | 52 participants (Actual) | Interventional | 2014-12-16 | Completed | |||
| Fiskespisestudiene 2011-2014. Spiseforsøk Med Fisk. Delstudie 2: Studie av Mulige Effekter av Fet og Mager Fisk på Glukosemetabolismen og inflammasjonsmarkører i Overvektige Voksne.[NCT02350595] | 76 participants (Actual) | Interventional | 2011-08-31 | Completed | |||
| Preventing Overweight Using Novel Dietary Strategies (Pounds Lost)[NCT00072995] | 811 participants | Interventional | 2003-09-30 | Completed | |||
| A Randomised, Double-blinded, Cross-over, Placebo- Controlled Pilot Study to Investigate the Effect of Tomato Extract on TMAO in Overweight or Obese Adults[NCT04160481] | 37 participants (Actual) | Interventional | 2019-11-12 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 trials available for trimethyloxamine and Overweight
| Article | Year |
|---|---|
Effects of a diet based on the Dietary Guidelines on vascular health and TMAO in women with cardiometabolic risk factors.
Topics: Cardiometabolic Risk Factors; Chromatography, Liquid; Diet; Female; Humans; Methylamines; Nutrition | 2022 |
A water-soluble tomato extract rich in secondary plant metabolites lowers trimethylamine-n-oxide and modulates gut microbiota: a randomized, double-blind, placebo-controlled cross-over study in overweight and obese adults.
Topics: Adult; Cross-Over Studies; Gastrointestinal Microbiome; Humans; Methylamines; Obesity; Overweight; O | 2023 |
TMAO, creatine and 1-methylhistidine in serum and urine are potential biomarkers of cod and salmon intake: a randomised clinical trial in adults with overweight or obesity.
Topics: Adult; Animals; Biomarkers; Creatine; Humans; Methylamines; Methylhistidines; Obesity; Overweight; S | 2020 |
Whole egg consumption increases plasma choline and betaine without affecting TMAO levels or gut microbiome in overweight postmenopausal women.
Topics: Aged; Bacteria; Betaine; Choline; Cross-Over Studies; Diet; Eggs; Feces; Female; Gastrointestinal Mi | 2020 |
Gut microbiota metabolites, amino acid metabolites and improvements in insulin sensitivity and glucose metabolism: the POUNDS Lost trial.
Topics: Adult; Amino Acids; Carnitine; Choline; Diet, Reducing; Female; Gastrointestinal Microbiome; Glucose | 2019 |
Circulating Gut Microbiota Metabolite Trimethylamine N-Oxide (TMAO) and Changes in Bone Density in Response to Weight Loss Diets: The POUNDS Lost Trial.
Topics: Absorptiometry, Photon; Adult; Bone Density; Carnitine; Choline; Diabetes Mellitus, Type 2; Diet, Re | 2019 |
Diets high in resistant starch increase plasma levels of trimethylamine-N-oxide, a gut microbiome metabolite associated with CVD risk.
Topics: Adult; Biomarkers; Body Mass Index; California; Cardiovascular Diseases; Cross-Over Studies; Diet, C | 2016 |