trimethyloxamine has been researched along with Obesity in 35 studies
trimethyloxamine: used in manufacture of quaternary ammonium cpds; insect attractant; warming agent for gas; oxidant; structure
trimethylamine N-oxide : A tertiary amine oxide resulting from the oxidation of the amino group of trimethylamine.
Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Obesity has repeatedly been linked to reorganization of the gut microbiome, yet to this point obesity therapeutics have been targeted exclusively toward the human host." | 5.72 | Gut microbe-targeted choline trimethylamine lyase inhibition improves obesity via rewiring of host circadian rhythms. ( Allen, FM; Anderson, JT; Armstrong, AR; Banerjee, R; Brown, AL; Brown, JM; Buffa, JA; Burrows, A; Cook, K; Ferguson, D; Finney, C; Fung, KK; Garcia-Garcia, JC; Gliniak, CM; Goudarzi, M; Gromovsky, AD; Hazen, SL; Helsley, RN; Horak, A; Keshavarzian, A; Lusis, AJ; Mak, TD; Massey, W; McMillan, A; Mehrabian, M; Neumann, C; Orabi, D; Osborn, LJ; Sangwan, N; Schugar, RC; Swanson, G; Wang, Z; Willard, B, 2022) |
| "Our findings underscore the importance of changes in TMAO, choline and L-carnitine in improving insulin sensitivity during a weight-loss intervention for obese patients." | 5.30 | Gut microbiota metabolites, amino acid metabolites and improvements in insulin sensitivity and glucose metabolism: the POUNDS Lost trial. ( Bray, GA; DiDonato, JA; Heianza, Y; Li, X; Qi, L; Sacks, FM; Sun, D, 2019) |
| " We examined associations of weight loss diet-induced changes in a gut microbiota-related metabolite trimethylamine N-oxide (TMAO), and its precursors (choline and l-carnitine), with changes in bone mineral density (BMD) considering diabetes-related factors." | 5.30 | Circulating Gut Microbiota Metabolite Trimethylamine N-Oxide (TMAO) and Changes in Bone Density in Response to Weight Loss Diets: The POUNDS Lost Trial. ( Bray, GA; Chen, Y; DiDonato, JA; Heianza, Y; LeBoff, MS; Li, X; Pei, X; Qi, L; Sacks, FM; Sun, D; Zhou, T, 2019) |
| " We examined associations of 6-month changes in blood metabolites (TMAO, choline, and l-carnitine) with improvements in body weight (BW), waist circumference (WC), body fat composition, fat distribution, and resting energy expenditure (REE)." | 5.27 | Changes in Gut Microbiota-Related Metabolites and Long-term Successful Weight Loss in Response to Weight-Loss Diets: The POUNDS Lost Trial. ( Bray, GA; Heianza, Y; Qi, L; Sacks, FM; Smith, SR; Sun, D, 2018) |
| "Trimethylamine N-oxide (TMAO), choline and betaine serum levels have been associated with metabolic diseases including type 2 diabetes (T2D) and non-alcoholic fatty liver disease (NAFLD)." | 4.02 | Trimethylamine N-oxide levels are associated with NASH in obese subjects with type 2 diabetes. ( Aguilar-Salinas, C; Campos-Pérez, F; Canizales-Quinteros, S; Gómez-Pérez, F; González-González, I; Grandini-Rosales, P; Hazen, SL; Hernández-Pando, R; Huertas-Vazquez, A; Hui, ST; Larrieta-Carrasco, E; León-Mimila, P; Li, XS; López-Contreras, B; Lusis, AJ; Macías-Kauffer, L; Morán-Ramos, S; Ocampo-Medina, E; Olivares-Arevalo, M; Shih, DM; Villamil-Ramírez, H; Villarreal-Molina, T; Wang, Z, 2021) |
| "Previous studies suggested the potential associations of trimethylamine N-oxide (TMAO) and its metabolic precursor l-carnitine with obesity." | 3.96 | Systematic investigation of the relationships of trimethylamine ( Gao, X; Randell, E; Sun, G; Tian, Y; Zhou, H, 2020) |
| " In the current study, we summarized the evidence related to the association of circulating TMAO with the risk of obesity measurements, including body mass index (BMI), waist circumference (WC), and waist-to-hip ratio (WHR) in a two-class and dose-response meta-analysis of observational studies." | 2.66 | Gut microbiota-derived metabolite trimethylamine N-oxide (TMAO) potentially increases the risk of obesity in adults: An exploratory systematic review and dose-response meta- analysis. ( Asghari-Jafarabadi, M; Dehghan, P; Farhangi, MA; Nikniaz, L; Nikniaz, Z, 2020) |
| "Dysbiosis is associated with intestinal inflammation and reduced integrity of the gut barrier, which in turn increases circulating levels of bacterial structural components and microbial metabolites that may facilitate the development of CVD." | 2.58 | The gut microbiota as a novel regulator of cardiovascular function and disease. ( Battson, ML; Gentile, CL; Lee, DM; Weir, TL, 2018) |
| "Obesity has repeatedly been linked to reorganization of the gut microbiome, yet to this point obesity therapeutics have been targeted exclusively toward the human host." | 1.72 | Gut microbe-targeted choline trimethylamine lyase inhibition improves obesity via rewiring of host circadian rhythms. ( Allen, FM; Anderson, JT; Armstrong, AR; Banerjee, R; Brown, AL; Brown, JM; Buffa, JA; Burrows, A; Cook, K; Ferguson, D; Finney, C; Fung, KK; Garcia-Garcia, JC; Gliniak, CM; Goudarzi, M; Gromovsky, AD; Hazen, SL; Helsley, RN; Horak, A; Keshavarzian, A; Lusis, AJ; Mak, TD; Massey, W; McMillan, A; Mehrabian, M; Neumann, C; Orabi, D; Osborn, LJ; Sangwan, N; Schugar, RC; Swanson, G; Wang, Z; Willard, B, 2022) |
| "Obesity is a main contributing factor for the development of glucose intolerance and type 2 diabetes mellitus (T2D)." | 1.62 | Roux-en-Y Gastric Bypass Improved Insulin Resistance via Alteration of the Human Gut Microbiome and Alleviation of Endotoxemia. ( Li, D; Shi, Q; Wang, C; Wang, Q; Yang, H; Yin, Z; Yu, S; Zhong, H, 2021) |
| "Obesity is considered an important factor that increases the risk of colorectal cancer (CRC)." | 1.56 | Gut Microbiota-Mediated Inflammation and Gut Permeability in Patients with Obesity and Colorectal Cancer. ( Gómez-Millán, J; Laborda-Illanes, A; Medina, JA; Ordóñez, R; Otero, A; Plaza-Andrade, I; Queipo-Ortuño, MI; Ramos-Molina, B; Sánchez-Alcoholado, L, 2020) |
| "Childhood obesity has become a prevalent risk to health of children and teenagers." | 1.38 | Comparison of serum metabolite compositions between obese and lean growing pigs using an NMR-based metabonomic approach. ( Blachier, F; Hao, F; He, Q; Kong, X; Li, P; Ren, P; Tang, H; Wu, G; Wu, Y; Yin, Y, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 17 (48.57) | 24.3611 |
| 2020's | 18 (51.43) | 2.80 |
| Authors | Studies |
|---|---|
| Krishnan, S | 1 |
| Gertz, ER | 1 |
| Adams, SH | 1 |
| Newman, JW | 1 |
| Pedersen, TL | 1 |
| Keim, NL | 1 |
| Bennett, BJ | 2 |
| Schugar, RC | 2 |
| Gliniak, CM | 1 |
| Osborn, LJ | 1 |
| Massey, W | 1 |
| Sangwan, N | 1 |
| Horak, A | 1 |
| Banerjee, R | 1 |
| Orabi, D | 1 |
| Helsley, RN | 2 |
| Brown, AL | 2 |
| Burrows, A | 2 |
| Finney, C | 1 |
| Fung, KK | 1 |
| Allen, FM | 1 |
| Ferguson, D | 2 |
| Gromovsky, AD | 2 |
| Neumann, C | 1 |
| Cook, K | 1 |
| McMillan, A | 1 |
| Buffa, JA | 1 |
| Anderson, JT | 1 |
| Mehrabian, M | 1 |
| Goudarzi, M | 1 |
| Willard, B | 2 |
| Mak, TD | 1 |
| Armstrong, AR | 1 |
| Swanson, G | 1 |
| Keshavarzian, A | 1 |
| Garcia-Garcia, JC | 1 |
| Wang, Z | 5 |
| Lusis, AJ | 3 |
| Hazen, SL | 5 |
| Brown, JM | 3 |
| Rehman, A | 1 |
| Tyree, SM | 1 |
| Fehlbaum, S | 1 |
| DunnGalvin, G | 1 |
| Panagos, CG | 1 |
| Guy, B | 1 |
| Patel, S | 1 |
| Dinan, TG | 1 |
| Duttaroy, AK | 2 |
| Duss, R | 1 |
| Steinert, RE | 1 |
| Bi, SH | 1 |
| Su, C | 1 |
| Yang, P | 1 |
| Zhang, X | 1 |
| Wang, Y | 2 |
| Tang, W | 1 |
| Yang, W | 1 |
| He, L | 1 |
| Hagen, IV | 1 |
| Helland, A | 1 |
| Bratlie, M | 1 |
| Midttun, Ø | 1 |
| McCann, A | 1 |
| Sveier, H | 1 |
| Rosenlund, G | 1 |
| Mellgren, G | 1 |
| Ueland, PM | 1 |
| Gudbrandsen, OA | 1 |
| Eyupoglu, ND | 1 |
| Caliskan Guzelce, E | 1 |
| Acikgoz, A | 1 |
| Uyanik, E | 1 |
| Bjørndal, B | 1 |
| Berge, RK | 2 |
| Svardal, A | 2 |
| Yildiz, BO | 1 |
| Wu, T | 1 |
| Gao, Y | 1 |
| Hao, J | 1 |
| Geng, J | 1 |
| Zhang, J | 1 |
| Yin, J | 1 |
| Liu, R | 1 |
| Sui, W | 1 |
| Gong, L | 1 |
| Zhang, M | 1 |
| Dehghan, P | 1 |
| Farhangi, MA | 1 |
| Nikniaz, L | 1 |
| Nikniaz, Z | 1 |
| Asghari-Jafarabadi, M | 1 |
| Zhu, C | 1 |
| Sawrey-Kubicek, L | 1 |
| Bardagjy, AS | 1 |
| Houts, H | 1 |
| Tang, X | 1 |
| Sacchi, R | 1 |
| Randolph, JM | 1 |
| Steinberg, FM | 1 |
| Zivkovic, AM | 1 |
| León-Mimila, P | 1 |
| Villamil-Ramírez, H | 1 |
| Li, XS | 2 |
| Shih, DM | 2 |
| Hui, ST | 1 |
| Ocampo-Medina, E | 1 |
| López-Contreras, B | 1 |
| Morán-Ramos, S | 1 |
| Olivares-Arevalo, M | 1 |
| Grandini-Rosales, P | 1 |
| Macías-Kauffer, L | 1 |
| González-González, I | 1 |
| Hernández-Pando, R | 1 |
| Gómez-Pérez, F | 1 |
| Campos-Pérez, F | 1 |
| Aguilar-Salinas, C | 1 |
| Larrieta-Carrasco, E | 1 |
| Villarreal-Molina, T | 1 |
| Huertas-Vazquez, A | 1 |
| Canizales-Quinteros, S | 1 |
| Gao, X | 1 |
| Sun, G | 2 |
| Randell, E | 1 |
| Tian, Y | 1 |
| Zhou, H | 1 |
| Sánchez-Alcoholado, L | 1 |
| Ordóñez, R | 1 |
| Otero, A | 1 |
| Plaza-Andrade, I | 1 |
| Laborda-Illanes, A | 1 |
| Medina, JA | 1 |
| Ramos-Molina, B | 1 |
| Gómez-Millán, J | 1 |
| Queipo-Ortuño, MI | 1 |
| Sawicka, AK | 1 |
| Renzi, G | 1 |
| Olek, RA | 1 |
| Fikri, AM | 1 |
| Smyth, R | 1 |
| Kumar, V | 1 |
| Al-Abadla, Z | 1 |
| Abusnana, S | 1 |
| Munday, MR | 1 |
| Kwee, LC | 1 |
| Ilkayeva, O | 1 |
| Muehlbauer, MJ | 1 |
| Bihlmeyer, N | 1 |
| Wolfe, B | 1 |
| Purnell, JQ | 1 |
| Xavier Pi-Sunyer, F | 1 |
| Chen, H | 1 |
| Bahnson, J | 1 |
| Newgard, CB | 1 |
| Shah, SH | 1 |
| Laferrère, B | 1 |
| Argyridou, S | 1 |
| Davies, MJ | 1 |
| Biddle, GJH | 1 |
| Bernieh, D | 1 |
| Suzuki, T | 1 |
| Dawkins, NP | 1 |
| Rowlands, AV | 1 |
| Khunti, K | 1 |
| Smith, AC | 1 |
| Yates, T | 1 |
| Shi, Q | 1 |
| Wang, Q | 1 |
| Zhong, H | 1 |
| Li, D | 1 |
| Yu, S | 1 |
| Yang, H | 1 |
| Wang, C | 1 |
| Yin, Z | 2 |
| Yoo, W | 1 |
| Zieba, JK | 1 |
| Foegeding, NJ | 1 |
| Torres, TP | 1 |
| Shelton, CD | 1 |
| Shealy, NG | 1 |
| Byndloss, AJ | 1 |
| Cevallos, SA | 1 |
| Gertz, E | 1 |
| Tiffany, CR | 1 |
| Thomas, JD | 1 |
| Litvak, Y | 1 |
| Nguyen, H | 1 |
| Olsan, EE | 1 |
| Rathmell, JC | 1 |
| Major, AS | 1 |
| Bäumler, AJ | 1 |
| Byndloss, MX | 1 |
| Warrier, M | 1 |
| Heine, M | 1 |
| Chatterjee, A | 1 |
| Li, L | 1 |
| Meng, Y | 1 |
| Kim, H | 1 |
| Che, N | 1 |
| Pan, C | 1 |
| Lee, RG | 1 |
| Crooke, RM | 1 |
| Graham, MJ | 1 |
| Morton, RE | 1 |
| Langefeld, CD | 1 |
| Das, SK | 1 |
| Rudel, LL | 1 |
| Zein, N | 1 |
| McCullough, AJ | 1 |
| Dasarathy, S | 1 |
| Tang, WHW | 1 |
| Erokwu, BO | 1 |
| Flask, CA | 1 |
| Laakso, M | 1 |
| Civelek, M | 1 |
| Naga Prasad, SV | 1 |
| Heeren, J | 1 |
| Dumas, ME | 1 |
| Rothwell, AR | 1 |
| Hoyles, L | 1 |
| Aranias, T | 1 |
| Chilloux, J | 1 |
| Calderari, S | 1 |
| Noll, EM | 1 |
| Péan, N | 1 |
| Boulangé, CL | 1 |
| Blancher, C | 1 |
| Barton, RH | 1 |
| Gu, Q | 1 |
| Fearnside, JF | 1 |
| Deshayes, C | 1 |
| Hue, C | 1 |
| Scott, J | 1 |
| Nicholson, JK | 1 |
| Gauguier, D | 1 |
| Morris, A | 1 |
| Subramaniam, S | 1 |
| Fletcher, C | 1 |
| Liu, N | 1 |
| Bian, X | 1 |
| Yu, R | 1 |
| Su, X | 1 |
| Zhang, B | 1 |
| Heianza, Y | 3 |
| Sun, D | 3 |
| Smith, SR | 1 |
| Bray, GA | 3 |
| Sacks, FM | 3 |
| Qi, L | 3 |
| Battson, ML | 1 |
| Lee, DM | 1 |
| Weir, TL | 1 |
| Gentile, CL | 1 |
| Li, X | 3 |
| DiDonato, JA | 2 |
| Cash, JG | 1 |
| Konaniah, E | 1 |
| Hegde, N | 1 |
| Kuhel, DG | 1 |
| Watanabe, M | 1 |
| Romick-Rosendale, L | 1 |
| Hui, DY | 1 |
| Angiletta, CJ | 1 |
| Griffin, LE | 1 |
| Steele, CN | 1 |
| Baer, DJ | 1 |
| Novotny, JA | 1 |
| Davy, KP | 1 |
| Neilson, AP | 1 |
| Erickson, ML | 1 |
| Malin, SK | 1 |
| Kirwan, JP | 1 |
| Zhou, T | 1 |
| Chen, Y | 1 |
| Pei, X | 1 |
| LeBoff, MS | 1 |
| Trøseid, M | 1 |
| Hov, JR | 1 |
| Nestvold, TK | 1 |
| Thoresen, H | 1 |
| Lappegård, KT | 1 |
| Milani, C | 1 |
| Ferrario, C | 1 |
| Turroni, F | 1 |
| Duranti, S | 1 |
| Mangifesta, M | 1 |
| van Sinderen, D | 1 |
| Ventura, M | 1 |
| Bergeron, N | 1 |
| Williams, PT | 1 |
| Lamendella, R | 1 |
| Faghihnia, N | 1 |
| Grube, A | 1 |
| Knight, R | 1 |
| Jansson, JK | 1 |
| Krauss, RM | 1 |
| He, Q | 1 |
| Ren, P | 1 |
| Kong, X | 1 |
| Wu, Y | 1 |
| Wu, G | 1 |
| Li, P | 1 |
| Hao, F | 1 |
| Tang, H | 1 |
| Blachier, F | 1 |
| Yin, Y | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Individual Metabolism and Physiology Signature Study[NCT02298725] | 52 participants (Actual) | Interventional | 2014-12-16 | Completed | |||
| Fiskespisestudiene 2011-2014. Spiseforsøk Med Fisk. Delstudie 2: Studie av Mulige Effekter av Fet og Mager Fisk på Glukosemetabolismen og inflammasjonsmarkører i Overvektige Voksne.[NCT02350595] | 76 participants (Actual) | Interventional | 2011-08-31 | Completed | |||
| The Effects of an 8-week Vegan Diet on Trimethylamine-N-Oxide (TMAO) Levels and Post-challenge Glucose Levels in Individuals With Dysglycaemia (The Plant Your Health Study)[NCT03315988] | 28 participants (Actual) | Interventional | 2017-10-04 | Completed | |||
| Analysis of MicroBial Metabolites After Eating Refined Food[NCT04308473] | 46 participants (Actual) | Interventional | 2020-09-01 | Active, not recruiting | |||
| Preventing Overweight Using Novel Dietary Strategies (Pounds Lost)[NCT00072995] | 811 participants | Interventional | 2003-09-30 | Completed | |||
| Longitudinal Profiling of Gut Microbiome in Overweight or Obese Participants on a Modified Atkins Diet: a Prospective Cohort Study[NCT04207879] | 75 participants (Actual) | Observational | 2020-01-01 | Active, not recruiting | |||
| A Randomised, Double-blinded, Cross-over, Placebo- Controlled Pilot Study to Investigate the Effect of Tomato Extract on TMAO in Overweight or Obese Adults[NCT04160481] | 37 participants (Actual) | Interventional | 2019-11-12 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for trimethyloxamine and Obesity
| Article | Year |
|---|---|
Gut microbiota-derived metabolite trimethylamine N-oxide (TMAO) potentially increases the risk of obesity in adults: An exploratory systematic review and dose-response meta- analysis.
Topics: Adult; Body Mass Index; Dose-Response Relationship, Drug; Gastrointestinal Microbiome; Humans; Methy | 2020 |
The bright and the dark sides of L-carnitine supplementation: a systematic review.
Topics: Age Factors; Body Composition; Carnitine; Cognition; Dietary Carbohydrates; Dietary Supplements; Ene | 2020 |
Role of Gut Microbiota and Their Metabolites on Atherosclerosis, Hypertension and Human Blood Platelet Function: A Review.
Topics: Animals; Atherosclerosis; Blood Platelets; Cardiovascular Diseases; Fatty Acids, Volatile; Gastroint | 2021 |
Trimethylamine N-oxide: breathe new life.
Topics: Animals; Brain Diseases; Heart Failure; Humans; Methylamines; Neoplasms; Obesity; Thrombosis | 2018 |
The gut microbiota as a novel regulator of cardiovascular function and disease.
Topics: Aging; Animals; Anti-Bacterial Agents; Atherosclerosis; Bile Acids and Salts; Cardiovascular Disease | 2018 |
12 trials available for trimethyloxamine and Obesity
| Article | Year |
|---|---|
Effects of a diet based on the Dietary Guidelines on vascular health and TMAO in women with cardiometabolic risk factors.
Topics: Cardiometabolic Risk Factors; Chromatography, Liquid; Diet; Female; Humans; Methylamines; Nutrition | 2022 |
A water-soluble tomato extract rich in secondary plant metabolites lowers trimethylamine-n-oxide and modulates gut microbiota: a randomized, double-blind, placebo-controlled cross-over study in overweight and obese adults.
Topics: Adult; Cross-Over Studies; Gastrointestinal Microbiome; Humans; Methylamines; Obesity; Overweight; O | 2023 |
TMAO, creatine and 1-methylhistidine in serum and urine are potential biomarkers of cod and salmon intake: a randomised clinical trial in adults with overweight or obesity.
Topics: Adult; Animals; Biomarkers; Creatine; Humans; Methylamines; Methylhistidines; Obesity; Overweight; S | 2020 |
Whole egg consumption increases plasma choline and betaine without affecting TMAO levels or gut microbiome in overweight postmenopausal women.
Topics: Aged; Bacteria; Betaine; Choline; Cross-Over Studies; Diet; Eggs; Feces; Female; Gastrointestinal Mi | 2020 |
Metabolites and diabetes remission after weight loss.
Topics: Amino Acids, Branched-Chain; Bariatric Surgery; Betaine; Biomarkers; Choline; Diabetes Mellitus, Typ | 2021 |
Evaluation of an 8-Week Vegan Diet on Plasma Trimethylamine-N-Oxide and Postchallenge Glucose in Adults with Dysglycemia or Obesity.
Topics: Adult; Diet, Vegan; Female; Glucose; Humans; Male; Methylamines; Obesity; Oxides; Prospective Studie | 2021 |
Changes in Gut Microbiota-Related Metabolites and Long-term Successful Weight Loss in Response to Weight-Loss Diets: The POUNDS Lost Trial.
Topics: Adipose Tissue, White; Adiposity; Adult; Body Weight; Caloric Restriction; Carnitine; Choline; Diabe | 2018 |
Changes in Gut Microbiota-Related Metabolites and Long-term Successful Weight Loss in Response to Weight-Loss Diets: The POUNDS Lost Trial.
Topics: Adipose Tissue, White; Adiposity; Adult; Body Weight; Caloric Restriction; Carnitine; Choline; Diabe | 2018 |
Changes in Gut Microbiota-Related Metabolites and Long-term Successful Weight Loss in Response to Weight-Loss Diets: The POUNDS Lost Trial.
Topics: Adipose Tissue, White; Adiposity; Adult; Body Weight; Caloric Restriction; Carnitine; Choline; Diabe | 2018 |
Changes in Gut Microbiota-Related Metabolites and Long-term Successful Weight Loss in Response to Weight-Loss Diets: The POUNDS Lost Trial.
Topics: Adipose Tissue, White; Adiposity; Adult; Body Weight; Caloric Restriction; Carnitine; Choline; Diabe | 2018 |
Gut microbiota metabolites, amino acid metabolites and improvements in insulin sensitivity and glucose metabolism: the POUNDS Lost trial.
Topics: Adult; Amino Acids; Carnitine; Choline; Diet, Reducing; Female; Gastrointestinal Microbiome; Glucose | 2019 |
Impact of short-term flavanol supplementation on fasting plasma trimethylamine N-oxide concentrations in obese adults.
Topics: Adult; Body Mass Index; Chocolate; Fasting; Female; Flavonoids; Humans; Male; Methylamines; Middle A | 2018 |
Effects of Lifestyle Intervention on Plasma Trimethylamine N-Oxide in Obese Adults.
Topics: Adiposity; Aged; Blood Glucose; Body Composition; Body Mass Index; Caloric Restriction; Diet, Reduci | 2019 |
Circulating Gut Microbiota Metabolite Trimethylamine N-Oxide (TMAO) and Changes in Bone Density in Response to Weight Loss Diets: The POUNDS Lost Trial.
Topics: Absorptiometry, Photon; Adult; Bone Density; Carnitine; Choline; Diabetes Mellitus, Type 2; Diet, Re | 2019 |
Diets high in resistant starch increase plasma levels of trimethylamine-N-oxide, a gut microbiome metabolite associated with CVD risk.
Topics: Adult; Biomarkers; Body Mass Index; California; Cardiovascular Diseases; Cross-Over Studies; Diet, C | 2016 |
18 other studies available for trimethyloxamine and Obesity
| Article | Year |
|---|---|
Gut microbe-targeted choline trimethylamine lyase inhibition improves obesity via rewiring of host circadian rhythms.
Topics: Animals; Choline; Circadian Rhythm; Diet, High-Fat; Enzyme Inhibitors; Gastrointestinal Microbiome; | 2022 |
Higher serum trimethylamine N-oxide (TMAO) levels are associated with increased visceral fat in hemodialysis patients.
Topics: Atherosclerosis; Humans; Intra-Abdominal Fat; Methylamines; Obesity; Renal Dialysis | 2023 |
Circulating gut microbiota metabolite trimethylamine N-oxide and oral contraceptive use in polycystic ovary syndrome.
Topics: Adolescent; Adult; Betaine; Blood Glucose; Cardiovascular Diseases; Carnitine; Choline; Female; Gast | 2019 |
Capsanthin extract prevents obesity, reduces serum TMAO levels and modulates the gut microbiota composition in high-fat-diet induced obese C57BL/6J mice.
Topics: Animals; Diet, High-Fat; Disease Models, Animal; Gastrointestinal Microbiome; Male; Methylamines; Mi | 2020 |
Trimethylamine N-oxide levels are associated with NASH in obese subjects with type 2 diabetes.
Topics: Adult; Betaine; Bile Acids and Salts; Biomarkers; Biopsy; Choline; Diabetes Mellitus, Type 2; Female | 2021 |
Systematic investigation of the relationships of trimethylamine
Topics: Adipocytes; Adipose Tissue, White; Adult; Animals; Body Composition; Body Weight; Carnitine; Diet, H | 2020 |
Gut Microbiota-Mediated Inflammation and Gut Permeability in Patients with Obesity and Colorectal Cancer.
Topics: Aged; Bacteria; Biomarkers; Body Mass Index; Colorectal Neoplasms; Dysbiosis; Feces; Female; Gastroi | 2020 |
Pre-diagnostic biomarkers of type 2 diabetes identified in the UAE's obese national population using targeted metabolomics.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Amino Acids, Branched-Chain; Biomarkers; Chromatography, Liqu | 2020 |
Roux-en-Y Gastric Bypass Improved Insulin Resistance via Alteration of the Human Gut Microbiome and Alleviation of Endotoxemia.
Topics: Acute-Phase Proteins; Carrier Proteins; Down-Regulation; Endotoxemia; Gastric Bypass; Gastrointestin | 2021 |
High-fat diet-induced colonocyte dysfunction escalates microbiota-derived trimethylamine
Topics: Animals; Cell Hypoxia; Choline; Colon; Diet, High-Fat; Energy Metabolism; Epithelial Cells; Escheric | 2021 |
The TMAO-Producing Enzyme Flavin-Containing Monooxygenase 3 Regulates Obesity and the Beiging of White Adipose Tissue.
Topics: Adipocytes, Beige; Animals; Diabetes Mellitus, Type 2; Female; Gene Expression; Humans; Male; Methyl | 2017 |
Microbial-Host Co-metabolites Are Prodromal Markers Predicting Phenotypic Heterogeneity in Behavior, Obesity, and Impaired Glucose Tolerance.
Topics: Adipocytes; Animals; Anxiety; Biomarkers; Blood Glucose; Cell Line; Endoplasmic Reticulum Stress; Ga | 2017 |
Gut microbiota: Link between the gut and adipose tissues.
Topics: Adipose Tissue; Adipose Tissue, White; Gastrointestinal Microbiome; Humans; Methylamines; Obesity; O | 2017 |
Gut microbial metabolite TMAO contributes to renal dysfunction in a mouse model of diet-induced obesity.
Topics: Animals; Diet, High-Fat; Disease Models, Animal; Gastrointestinal Microbiome; Hemodynamics; Inflamma | 2017 |
Therapeutic reduction of lysophospholipids in the digestive tract recapitulates the metabolic benefits of bariatric surgery and promotes diabetes remission.
Topics: Animals; Biphenyl Compounds; Diabetes Mellitus; Diet, High-Fat; Dietary Carbohydrates; Female; Gastr | 2018 |
Major Increase in Microbiota-Dependent Proatherogenic Metabolite TMAO One Year After Bariatric Surgery.
Topics: Adult; Atherosclerosis; Bariatric Surgery; Betaine; Body Mass Index; Cardiovascular Diseases; Carnit | 2016 |
The human gut microbiota and its interactive connections to diet.
Topics: Animals; Autoimmune Diseases; Bile Acids and Salts; Diet, Healthy; Diet, Western; Dysbiosis; Fatty A | 2016 |
Comparison of serum metabolite compositions between obese and lean growing pigs using an NMR-based metabonomic approach.
Topics: Animals; Blood Glucose; Body Composition; Choline; Glucagon; Insulin; Lipid Metabolism; Lipoproteins | 2012 |