Page last updated: 2024-10-20

trimethyloxamine and Metabolic Syndrome

trimethyloxamine has been researched along with Metabolic Syndrome in 12 studies

trimethyloxamine: used in manufacture of quaternary ammonium cpds; insect attractant; warming agent for gas; oxidant; structure
trimethylamine N-oxide : A tertiary amine oxide resulting from the oxidation of the amino group of trimethylamine.

Metabolic Syndrome: A cluster of symptoms that are risk factors for CARDIOVASCULAR DISEASES and TYPE 2 DIABETES MELLITUS. The major components of metabolic syndrome include ABDOMINAL OBESITY; atherogenic DYSLIPIDEMIA; HYPERTENSION; HYPERGLYCEMIA; INSULIN RESISTANCE; a proinflammatory state; and a prothrombotic (THROMBOSIS) state.

Research Excerpts

ExcerptRelevanceReference
"Choline was not significantly altered in MetS."1.48Changes to trimethylamine-N-oxide and its precursors in nascent metabolic syndrome. ( Huet, B; Jialal, I; Lent-Schochet, D; McLaughlin, M; Silva, R, 2018)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's8 (66.67)24.3611
2020's4 (33.33)2.80

Authors

AuthorsStudies
Ringel, C1
Dittrich, J1
Gaudl, A1
Schellong, P1
Beuchel, CF1
Baber, R1
Beutner, F1
Teren, A1
Engel, C1
Wirkner, K1
Thiele, H1
Büttner, P1
Löffler, M1
Scholz, M1
Thiery, J1
Ceglarek, U1
Kuo, CH1
Liu, CH1
Wang, JH1
Hsu, BG1
Gao, X1
Sun, C1
Zhang, Y2
Hu, S1
Li, D1
Bestavashvili, A1
Glazachev, O1
Ibragimova, S1
Suvorov, A1
Bestavasvili, A1
Ibraimov, S1
Zhang, X1
Pavlov, C1
Syrkina, E1
Syrkin, A1
Kopylov, P1
Chen, S1
Henderson, A1
Petriello, MC1
Romano, KA1
Gearing, M1
Miao, J1
Schell, M1
Sandoval-Espinola, WJ1
Tao, J1
Sha, B1
Graham, M1
Crooke, R1
Kleinridders, A1
Balskus, EP1
Rey, FE1
Morris, AJ1
Biddinger, SB1
Org, E1
Blum, Y1
Kasela, S1
Mehrabian, M1
Kuusisto, J1
Kangas, AJ1
Soininen, P1
Wang, Z1
Ala-Korpela, M1
Hazen, SL1
Laakso, M1
Lusis, AJ1
Lent-Schochet, D1
Silva, R1
McLaughlin, M1
Huet, B1
Jialal, I1
Canyelles, M1
Tondo, M1
Cedó, L1
Farràs, M1
Escolà-Gil, JC1
Blanco-Vaca, F1
Barrea, L1
Annunziata, G1
Muscogiuri, G1
Di Somma, C1
Laudisio, D1
Maisto, M1
de Alteriis, G1
Tenore, GC1
Colao, A1
Savastano, S1
Joris, BR1
Gloor, GB1
Tripolt, NJ1
Leber, B1
Triebl, A1
Köfeler, H1
Stadlbauer, V1
Sourij, H1
Mueller, DM1
Allenspach, M1
Othman, A1
Saely, CH1
Muendlein, A1
Vonbank, A1
Drexel, H1
von Eckardstein, A1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Developmental Impacts of MicroPLastics Exposure in Early Life[NCT06107933]40 participants (Anticipated)Observational2023-10-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for trimethyloxamine and Metabolic Syndrome

ArticleYear
Trimethylamine
    International journal of molecular sciences, 2018, Oct-19, Volume: 19, Issue:10

    Topics: Animals; Cholesterol; Gastrointestinal Microbiome; Gluconeogenesis; Humans; Lipogenesis; Liver; Meta

2018
Unaccounted risk of cardiovascular disease: the role of the microbiome in lipid metabolism.
    Current opinion in lipidology, 2019, Volume: 30, Issue:2

    Topics: Animals; Atherosclerosis; Bile Acids and Salts; Carnitine; Choline; Energy Metabolism; Fatty Acids,

2019

Trials

2 trials available for trimethyloxamine and Metabolic Syndrome

ArticleYear
Impact of Hypoxia-Hyperoxia Exposures on Cardiometabolic Risk Factors and TMAO Levels in Patients with Metabolic Syndrome.
    International journal of molecular sciences, 2023, Sep-24, Volume: 24, Issue:19

    Topics: Cardiometabolic Risk Factors; Female; Humans; Hyperoxia; Hypoxia; Metabolic Syndrome; Methylamines;

2023
Effect of Lactobacillus casei Shirota supplementation on trimethylamine-N-oxide levels in patients with metabolic syndrome: An open-label, randomized study.
    Atherosclerosis, 2015, Volume: 242, Issue:1

    Topics: Adult; Austria; Biomarkers; Chromatography, Liquid; Female; Gastrointestinal Microbiome; Humans; Int

2015

Other Studies

8 other studies available for trimethyloxamine and Metabolic Syndrome

ArticleYear
Association of plasma trimethylamine N-oxide levels with atherosclerotic cardiovascular disease and factors of the metabolic syndrome.
    Atherosclerosis, 2021, Volume: 335

    Topics: Adult; Atherosclerosis; Biomarkers; Cardiovascular Diseases; Humans; Metabolic Syndrome; Methylamine

2021
Serum Trimethylamine N-Oxide Levels Correlate with Metabolic Syndrome in Coronary Artery Disease Patients.
    International journal of environmental research and public health, 2022, 07-18, Volume: 19, Issue:14

    Topics: Biomarkers; C-Reactive Protein; Coronary Artery Disease; Glucose; Humans; Metabolic Syndrome; Methyl

2022
Dietary supplementation of L-carnitine ameliorates metabolic syndrome independent of trimethylamine
    Food & function, 2022, Nov-28, Volume: 13, Issue:23

    Topics: Animals; Carnitine; Diet, High-Fat; Dietary Supplements; Gastrointestinal Microbiome; Humans; Metabo

2022
Trimethylamine N-Oxide Binds and Activates PERK to Promote Metabolic Dysfunction.
    Cell metabolism, 2019, 12-03, Volume: 30, Issue:6

    Topics: Animals; eIF-2 Kinase; Gastrointestinal Microbiome; HEK293 Cells; Hep G2 Cells; Humans; Indoles; Ins

2019
Relationships between gut microbiota, plasma metabolites, and metabolic syndrome traits in the METSIM cohort.
    Genome biology, 2017, 04-13, Volume: 18, Issue:1

    Topics: Aged; Amino Acids; Bacteria; Blood Glucose; Body Mass Index; Cohort Studies; Diabetes Mellitus, Type

2017
Changes to trimethylamine-N-oxide and its precursors in nascent metabolic syndrome.
    Hormone molecular biology and clinical investigation, 2018, Apr-18, Volume: 35, Issue:2

    Topics: Adult; Aged; Biomarkers; Carnitine; Choline; Female; Humans; Inflammation; Male; Metabolic Syndrome;

2018
Trimethylamine-N-oxide (TMAO) as Novel Potential Biomarker of Early Predictors of Metabolic Syndrome.
    Nutrients, 2018, Dec-13, Volume: 10, Issue:12

    Topics: Adult; Biomarkers; Body Mass Index; Cross-Sectional Studies; Female; Habits; Humans; Life Style; Lin

2018
Plasma levels of trimethylamine-N-oxide are confounded by impaired kidney function and poor metabolic control.
    Atherosclerosis, 2015, Volume: 243, Issue:2

    Topics: Aged; Betaine; Biomarkers; Blood Glucose; Choline; Chromatography, Liquid; Coronary Angiography; Cor

2015