Page last updated: 2024-10-20

trimethyloxamine and Kidney Failure

trimethyloxamine has been researched along with Kidney Failure in 8 studies

trimethyloxamine: used in manufacture of quaternary ammonium cpds; insect attractant; warming agent for gas; oxidant; structure
trimethylamine N-oxide : A tertiary amine oxide resulting from the oxidation of the amino group of trimethylamine.

Kidney Failure: A severe irreversible decline in the ability of kidneys to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism.

Research Excerpts

ExcerptRelevanceReference
"Trimethylamine (TMA) is a tertiary amine with a characteristic fishy odour."2.53The complex metabolism of trimethylamine in humans: endogenous and exogenous sources. ( Bhargava, B; Chhibber-Goel, J; Gaur, A; Parakh, N; Sharma, A; Singhal, V, 2016)
"In individuals with type 1 diabetes, higher concentrations of plasma TMAO were associated with mortality, CVD events, and poor renal outcome, independent of conventional risk factors."1.51Utility of Plasma Concentration of Trimethylamine N-Oxide in Predicting Cardiovascular and Renal Complications in Individuals With Type 1 Diabetes. ( Ahluwalia, TS; Hansen, TW; Hazen, SL; Jorsal, A; Parving, HH; Pedersen, O; Rossing, P; Tarnow, L; Theilade, S; Tofte, N; Wang, Z; Winther, SA; Øllgaard, JC, 2019)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (50.00)24.3611
2020's4 (50.00)2.80

Authors

AuthorsStudies
Mafra, D1
Kemp, JA1
Leal, VO1
Cardozo, L1
Borges, NA1
Alvarenga, L1
Teixeira, KTR1
Stenvinkel, P1
Wang, M1
Li, XS2
Wang, Z3
de Oliveira Otto, MC1
Lemaitre, RN1
Fretts, A1
Sotoodehnia, N1
Budoff, M1
Nemet, I1
DiDonato, JA1
Tang, WHW1
Psaty, BM1
Siscovick, DS1
Hazen, SL3
Mozaffarian, D1
Korytowska-Przybylska, N1
Michorowska, S1
Wyczałkowska-Tomasik, A1
Pączek, L1
Giebułtowicz, J1
Li, W1
Huang, A1
Zhu, H1
Liu, X1
Huang, X1
Huang, Y2
Cai, X1
Lu, J1
Winther, SA1
Øllgaard, JC1
Tofte, N1
Tarnow, L1
Ahluwalia, TS1
Jorsal, A1
Theilade, S1
Parving, HH1
Hansen, TW1
Pedersen, O1
Rossing, P1
Tang, WH1
Kennedy, DJ1
Wu, Y1
Buffa, JA1
Agatisa-Boyle, B1
Levison, BS1
Fogelman, AM1
Chhibber-Goel, J1
Gaur, A1
Singhal, V1
Parakh, N1
Bhargava, B1
Sharma, A1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of Sevelamer Carbonate on Serum Trimethylamine-n-Oxide (TMAO) Level in Patients With Chronic Kidney Disease (CKD) Stage 3b-4: a Protocol of a Randomized, Parallel, Controlled Trial[NCT03596749]Phase 380 participants (Anticipated)Interventional2018-09-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for trimethyloxamine and Kidney Failure

ArticleYear
Consumption of Fish in Chronic Kidney Disease - A Matter of Depth.
    Molecular nutrition & food research, 2023, Volume: 67, Issue:9

    Topics: Animals; Gastrointestinal Microbiome; Methylamines; Renal Insufficiency; Renal Insufficiency, Chroni

2023
Gut microbiota-derived trimethylamine N-oxide is associated with poor prognosis in patients with heart failure.
    The Medical journal of Australia, 2020, Volume: 213, Issue:8

    Topics: Cause of Death; Gastrointestinal Microbiome; Heart Failure; Heart Transplantation; Hospitalization;

2020
The complex metabolism of trimethylamine in humans: endogenous and exogenous sources.
    Expert reviews in molecular medicine, 2016, Apr-29, Volume: 18

    Topics: Air Pollutants; Animals; Atherosclerosis; Diet; Humans; Metabolism, Inborn Errors; Methylamines; Neo

2016

Other Studies

5 other studies available for trimethyloxamine and Kidney Failure

ArticleYear
Trimethylamine N-oxide is associated with long-term mortality risk: the multi-ethnic study of atherosclerosis.
    European heart journal, 2023, 05-07, Volume: 44, Issue:18

    Topics: Adult; Atherosclerosis; Biomarkers; Cardiovascular Diseases; Dementia; Humans; Methylamines; Neoplas

2023
Development of a novel method for the simultaneous detection of trimethylamine N-oxide and creatinine in the saliva of patients with chronic kidney disease - Its utility in saliva as an alternative to blood.
    Journal of pharmaceutical and biomedical analysis, 2023, Sep-20, Volume: 234

    Topics: Biomarkers; Creatinine; Humans; Methylamines; Renal Insufficiency; Renal Insufficiency, Chronic; Sal

2023
Utility of Plasma Concentration of Trimethylamine N-Oxide in Predicting Cardiovascular and Renal Complications in Individuals With Type 1 Diabetes.
    Diabetes care, 2019, Volume: 42, Issue:8

    Topics: Aged; Biomarkers; Diabetes Mellitus, Type 1; Diabetic Cardiomyopathies; Diabetic Nephropathies; Fema

2019
Gut microbiota-dependent trimethylamine N-oxide (TMAO) pathway contributes to both development of renal insufficiency and mortality risk in chronic kidney disease.
    Circulation research, 2015, Jan-30, Volume: 116, Issue:3

    Topics: Aged; Aged, 80 and over; Animals; Biomarkers; Case-Control Studies; Female; Humans; Intestines; Male

2015
TMAO is both a biomarker and a renal toxin.
    Circulation research, 2015, Jan-30, Volume: 116, Issue:3

    Topics: Animals; Female; Humans; Male; Methylamines; Microbiota; Renal Insufficiency; Renal Insufficiency, C

2015