trimethyloxamine has been researched along with Kidney Failure, Chronic in 10 studies
trimethyloxamine: used in manufacture of quaternary ammonium cpds; insect attractant; warming agent for gas; oxidant; structure
trimethylamine N-oxide : A tertiary amine oxide resulting from the oxidation of the amino group of trimethylamine.
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The changes of intestinal bacteria in ESRD patients have contributed to the accumulation of gut-derived uremic toxins such as TMAO, indoxyl sulfate and indole-3-acetic acid." | 2.82 | [Gut-derived uremic toxin trimethylamine-N-oxide in cardiovascular disease under end-stage renal disease: an injury mechanism and therapeutic target]. ( Ren, Y; Wang, Z; Xue, J, 2022) |
| "L-Carnitine has important roles in intermediary metabolism and patients with end-stage renal disease who are undergoing hemodialysis may develop a secondary L-carnitine deficiency." | 2.72 | Oral L-carnitine: metabolite formation and hemodialysis. ( Bain, MA; Evans, AM; Faull, R; Milne, RW, 2006) |
| "In individuals with type 1 diabetes, higher concentrations of plasma TMAO were associated with mortality, CVD events, and poor renal outcome, independent of conventional risk factors." | 1.51 | Utility of Plasma Concentration of Trimethylamine N-Oxide in Predicting Cardiovascular and Renal Complications in Individuals With Type 1 Diabetes. ( Ahluwalia, TS; Hansen, TW; Hazen, SL; Jorsal, A; Parving, HH; Pedersen, O; Rossing, P; Tarnow, L; Theilade, S; Tofte, N; Wang, Z; Winther, SA; Øllgaard, JC, 2019) |
| "Thus TMAO levels in ESRD average about 40 fold those in NLS while BUN is 3 fold NLS." | 1.42 | Mechanism of Prominent Trimethylamine Oxide (TMAO) Accumulation in Hemodialysis Patients. ( DeOreo, P; Dobre, MA; Hai, X; Hostetter, TH; Landeras, V; Meyer, TW, 2015) |
| "Trimethylamine (TMA) is a short-chain tertiary aliphatic amine that is derived from the diet either directly from the consumption of foods high in TMA or by the intake of food high in precursors to TMA, such as trimethylamine-N-oxide (TMNO), choline and L-carnitine." | 1.33 | Accumulation of trimethylamine and trimethylamine-N-oxide in end-stage renal disease patients undergoing haemodialysis. ( Bain, MA; Evans, AM; Faull, R; Fornasini, G; Milne, RW, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 3 (30.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, D | 1 |
| Xu, X | 1 |
| Yang, Z | 1 |
| Ma, T | 1 |
| Nie, J | 1 |
| Dong, J | 1 |
| Ren, Y | 1 |
| Wang, Z | 2 |
| Xue, J | 1 |
| Zhang, P | 1 |
| Zou, JZ | 1 |
| Chen, J | 1 |
| Tan, X | 1 |
| Xiang, FF | 1 |
| Shen, B | 1 |
| Hu, JC | 1 |
| Wang, JL | 1 |
| Wang, YQ | 1 |
| Yu, JB | 1 |
| Nie, YX | 1 |
| Chen, XH | 1 |
| Yu, JW | 1 |
| Zhang, Z | 1 |
| Lv, WL | 1 |
| Xie, YQ | 1 |
| Cao, XS | 1 |
| Ding, XQ | 1 |
| Stubbs, JR | 1 |
| Stedman, MR | 1 |
| Liu, S | 1 |
| Long, J | 1 |
| Franchetti, Y | 1 |
| West, RE | 1 |
| Prokopienko, AJ | 1 |
| Mahnken, JD | 1 |
| Chertow, GM | 2 |
| Nolin, TD | 1 |
| Winther, SA | 1 |
| Øllgaard, JC | 1 |
| Tofte, N | 1 |
| Tarnow, L | 1 |
| Ahluwalia, TS | 1 |
| Jorsal, A | 1 |
| Theilade, S | 1 |
| Parving, HH | 1 |
| Hansen, TW | 1 |
| Hazen, SL | 1 |
| Pedersen, O | 1 |
| Rossing, P | 1 |
| Kaysen, GA | 1 |
| Johansen, KL | 1 |
| Dalrymple, LS | 1 |
| Kornak, J | 1 |
| Grimes, B | 1 |
| Dwyer, T | 1 |
| Chassy, AW | 1 |
| Fiehn, O | 1 |
| Hai, X | 1 |
| Landeras, V | 1 |
| Dobre, MA | 1 |
| DeOreo, P | 1 |
| Meyer, TW | 1 |
| Hostetter, TH | 1 |
| Bain, MA | 2 |
| Faull, R | 2 |
| Fornasini, G | 1 |
| Milne, RW | 2 |
| Evans, AM | 2 |
| Bell, JD | 1 |
| Lee, JA | 1 |
| Lee, HA | 1 |
| Sadler, PJ | 1 |
| Wilkie, DR | 1 |
| Woodham, RH | 1 |
1 review available for trimethyloxamine and Kidney Failure, Chronic
| Article | Year |
|---|---|
[Gut-derived uremic toxin trimethylamine-N-oxide in cardiovascular disease under end-stage renal disease: an injury mechanism and therapeutic target].
Topics: Cardiovascular Diseases; Humans; Kidney Failure, Chronic; Methylamines; Oxides; Uremic Toxins | 2022 |
1 trial available for trimethyloxamine and Kidney Failure, Chronic
| Article | Year |
|---|---|
Oral L-carnitine: metabolite formation and hemodialysis.
Topics: Administration, Oral; Adult; Aged; Carnitine; Humans; Kidney Failure, Chronic; Male; Methylamines; M | 2006 |
8 other studies available for trimethyloxamine and Kidney Failure, Chronic
| Article | Year |
|---|---|
Trimethylamine-N-oxide (TMAO) and clinical outcomes in patients with end-stage kidney disease receiving peritoneal dialysis.
Topics: Biomarkers; Cardiovascular Diseases; Humans; Kidney Failure, Chronic; Oxides; Peritoneal Dialysis; P | 2022 |
Association of trimethylamine
Topics: Adult; Aged; Biomarkers; Cardiovascular Diseases; Cause of Death; China; Comorbidity; Female; Humans | 2020 |
Trimethylamine
Topics: Adult; Aged; Angina, Unstable; Calcimimetic Agents; Cardiovascular Diseases; Cinacalcet; Female; Hos | 2019 |
Utility of Plasma Concentration of Trimethylamine N-Oxide in Predicting Cardiovascular and Renal Complications in Individuals With Type 1 Diabetes.
Topics: Aged; Biomarkers; Diabetes Mellitus, Type 1; Diabetic Cardiomyopathies; Diabetic Nephropathies; Fema | 2019 |
Associations of Trimethylamine N-Oxide With Nutritional and Inflammatory Biomarkers and Cardiovascular Outcomes in Patients New to Dialysis.
Topics: Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Chromatography, Liquid; Cohort Studies; Com | 2015 |
Mechanism of Prominent Trimethylamine Oxide (TMAO) Accumulation in Hemodialysis Patients.
Topics: Adult; Biomarkers; Case-Control Studies; Creatinine; Female; Humans; Kidney Failure, Chronic; Male; | 2015 |
Accumulation of trimethylamine and trimethylamine-N-oxide in end-stage renal disease patients undergoing haemodialysis.
Topics: Adult; Biomarkers; Case-Control Studies; Disease Progression; Female; Follow-Up Studies; Humans; Kid | 2006 |
Nuclear magnetic resonance studies of blood plasma and urine from subjects with chronic renal failure: identification of trimethylamine-N-oxide.
Topics: Adult; Creatinine; Dimethylamines; Female; Humans; Kidney Failure, Chronic; Magnetic Resonance Spect | 1991 |